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Showing 1 to 12 of 512 entries
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[Cytotoxic effects of local anesthesia through lidocaine/ropivacaine on human melanoma cell lines].

Revista brasileira de anestesiologia

Kang DK, Zhao LY, Wang HL.
PMID: 27639508
Rev Bras Anestesiol. 2016 Nov - Dec;66(6):594-602. doi: 10.1016/j.bjan.2016.08.002. Epub 2016 Sep 14.

BACKGROUND: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has been reported for several local anesthetics used in humans, which is not well investigated. In the present study, the cytotoxicity of lidocaine, ropivacaine and the combination of...

The Prevalence and Management of Systemic Amyloidosis in Western Countries.

Kidney diseases (Basel, Switzerland)

Nienhuis HL, Bijzet J, Hazenberg BP.
PMID: 27536687
Kidney Dis (Basel). 2016 Apr;2(1):10-9. doi: 10.1159/000444206. Epub 2016 Feb 25.

BACKGROUND: Amyloidosis has been a mystery for centuries, but research of the last decennia has clarified many of the secrets of this group of diseases. A protein-based classification of amyloidosis helps to understand problems that were part of the...

Isolated limb infusion chemotherapy with or without hemofiltration for recurrent limb melanoma.

World journal of clinical oncology

Cecchini S, Sarti D, Ricci S, Vergini LD, Sallei M, Serresi S, Ricotti G, Mulazzani L, Lattanzio F, Fiorentini G.
PMID: 26266102
World J Clin Oncol. 2015 Aug 10;6(4):57-63. doi: 10.5306/wjco.v6.i4.57.

AIM: To better define the efficacy and the safety of intra-arterial infusion performed with or without hemofiltration for recurrent limb melanoma.METHODS: Patients with the following characteristics were included in the study: recurrent limb melanoma not indicated for surgical resection,...

Can BuCyE conditioning regimen be an alternative treatment to BEAM at autologous transplantation in malignant lymphoma patients?: a single center experience.

International journal of clinical and experimental medicine

Berber I, Erkurt MA, Nizam I, Koroglu M, Kaya E, Kuku I, Bag HG.
PMID: 26629149
Int J Clin Exp Med. 2015 Sep 15;8(9):16308-14. eCollection 2015.

High-dose chemotherapy (HDC) applied together with autologous stem cell transplantation (ASCT) is a commonly used treatment modality in patients with malignant lymphoma. At present, there is a limited number of studies which compare toxicity and efficacy of various high-dose...

Clinical characteristics of critically ill cancer patients who are undergoing isolated limb perfusion.

Molecular and clinical oncology

Ñamendys-Silva SA, Ruiz-Beltran AM, Barragán-Dessavre M, Bautista-Ocampo AR, Meneses-García A, González-Chon O, Herrera-Gómez A.
PMID: 29142747
Mol Clin Oncol. 2017 Nov;7(5):747-750. doi: 10.3892/mco.2017.1401. Epub 2017 Aug 31.

The aim of the present study was to investigate the incidence of organ dysfunction, and to describe the clinical characteristics and intensive care unit (ICU) outcomes of critically ill cancer patients who were admitted to an oncological ICU during...

Bone-Specific Alkaline Phosphatase Levels among Patients with Multiple Myeloma Receiving Various Therapy Options.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Çetin G, Eşkazan AE, Ar MC, Aydın ŞÖ, Ferhanoğlu B, Soysal T, Başlar Z, Aydın Y.
PMID: 25541654
Turk J Haematol. 2014 Dec 05;31(4):374-80. doi: 10.4274/tjh.2013.0004.

OBJECTIVE: This study aimed to investigate the impact of the different therapy regimens used in multiple myeloma (MM) on bone-specific alkaline phosphatase (BALP) levels.MATERIALS AND METHODS: One hundred and thirteen patients with MM were included in the study. Patients...

Unknown primary nasopharyngeal melanoma presenting as severe recurrent epistaxis and hearing loss following treatment and remission of metastatic disease: A case report and literature review.

International journal of surgery case reports

Azoury SC, Crompton JG, Straughan DM, Klemen ND, Reardon ES, Beresnev TH, Hughes MS.
PMID: 25898283
Int J Surg Case Rep. 2015;10:232-5. doi: 10.1016/j.ijscr.2015.03.053. Epub 2015 Apr 01.

INTRODUCTION: Primary nasopharyngeal melanoma is an exceedingly rare pathology with unclear etiology and oftentimes obscure clinical presentation. Despite improved diagnostic capabilities, these lesions are often diagnosed at an advanced stage and associated prognosis is poor, partly due to high...

Different types of cell cycle- and apoptosis-related gene expressions alter in corticosteroid-, vincristine-, and melphalan-resistant u-266 multiple myeloma cell lines.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Mutlu P, Ural AU, Gündüz U.
PMID: 25330516
Turk J Haematol. 2014 Sep 05;31(3):231-8. doi: 10.4274/tjh.2013.0231.

OBJECTIVE: Hemophilia B is caused by coagulation defects in the factor IX gene located in Xq27.1 on the X chromosome. A wide range of mutations, showing extensive molecular heterogeneity, have been described in hemophilia B patients. Our study was...

A man with a fracture from minor trauma.

World journal of emergency medicine

Yang SM, Lo CM.
PMID: 25548606
World J Emerg Med. 2014;5(4):306-9. doi: 10.5847/wjem.j.issn.1920-8642.2014.04.011.

BACKGROUND: We commonly encounter fractures secondary to trauma on and off in our daily practice. While it is not uncommon to see fractures due to underlying pathology, we need to be on the alert when patients present atypically because...

Influence of PJ34 on the genotoxicity induced by melphalan in human multiple myeloma cells.

Archives of medical science : AMS

Xiong T, Chen X, Wei H, Xiao H.
PMID: 25995744
Arch Med Sci. 2015 Apr 25;11(2):301-6. doi: 10.5114/aoms.2014.43164. Epub 2015 Apr 23.

INTRODUCTION: The aim of this study was to evaluate the potential biological activity of N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride (PJ34) on the genotoxicity induced by melphalan in human multiple myeloma cells.MATERIAL AND METHODS: The inhibitory effects of the drugs on the growth...

Leukemia cells are sensitized to temozolomide, carmustine and melphalan by the inhibition of O.

Oncology letters

Arai H, Yamauchi T, Uzui K, Ueda T.
PMID: 26622581
Oncol Lett. 2015 Aug;10(2):845-849. doi: 10.3892/ol.2015.3307. Epub 2015 Jun 02.

The cytotoxicity of the monofunctional alkylator, temozolomide (TMZ), is known to be mediated by mismatch repair (MMR) triggered by O

Therapy-related acute promyelocytic leukemia in plasma cell myeloma treated with melphalan: a case report and literature review.

Blood research

Gu H, Kim YJ, Lee WI, Lee J, Yoon HJ, Park TS.
PMID: 28401104
Blood Res. 2017 Mar;52(1):62-64. doi: 10.5045/br.2017.52.1.62. Epub 2017 Mar 27.

No abstract available.

Showing 1 to 12 of 512 entries