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Showing 1 to 12 of 270 entries
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Distinct patterns of corticogeniculate feedback to different layers of the lateral geniculate nucleus.

Eye and brain

Ichida JM, Mavity-Hudson JA, Casagrande VA.
PMID: 25892906
Eye Brain. 2014 Sep;2014(6):57-73. doi: 10.2147/EB.S64281.

In primates, feedforward visual pathways from retina to lateral geniculate nucleus (LGN) are segregated to different layers. These layers also receive strong reciprocal feedback pathways from cortex. The degree to which feedforward streams in primates are segregated from feedback...

Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men.

Health promotion practice

Cornish EK, McKissic SA, Dean DAL, Griffith DM.
PMID: 26637233
Health Promot Pract. 2017 Jan;18(1):102-109. doi: 10.1177/1524839915614800. Epub 2016 Jul 10.

African American men are less likely than White men to meet physical activity recommendations, and few physical activity interventions have focused on the unique needs of African American men. Because health is not more important to men than fulfilling...

Correction to differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.

Biochemistry

Szulik MW, Pallan PS, Nocek B, Voehler M, Banerjee S, Brooks S, Joachimiak A, Egli M, Eichman BF, Stone MP.
PMID: 25860080
Biochemistry. 2015 Apr 21;54(15):2550. doi: 10.1021/acs.biochem.5b00344. Epub 2015 Apr 10.

No abstract available.

Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH.

BMC endocrine disorders

Gunawardana SC, Rocheleau JV, Head WS, Piston DW.
PMID: 15193158
BMC Endocr Disord. 2004 Jun 11;4(1):1. doi: 10.1186/1472-6823-4-1.

BACKGROUND: Many mechanistic steps underlying nutrient-stimulated insulin secretion (NSIS) are poorly understood. The influence of intracellular pH (pHi) on insulin secretion is widely documented, and can be used as an investigative tool. This study demonstrates previously unknown effects of...

An Integrative Pathway-based Clinical-genomic Model for Cancer Survival Prediction.

Statistics & probability letters

Chen X, Wang L, Ishwaran H.
PMID: 21731150
Stat Probab Lett. 2010 Sep 07;80(17):1313-1319. doi: 10.1016/j.spl.2010.04.011.

Prediction models that use gene expression levels are now being proposed for personalized treatment of cancer, but building accurate models that are easy to interpret remains a challenge. In this paper, we describe an integrative clinical-genomic approach that combines...

Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine.

Tetrahedron letters

Christov PP, Hawkins EK, Kett NR, Rizzo CJ.
PMID: 23935223
Tetrahedron Lett. 2013 Aug 07;54(32):4289-4291. doi: 10.1016/j.tetlet.2013.06.004.

We previously reported the synthesis of the 1,

Statistical strategies for microRNAseq batch effect reduction.

Translational cancer research

Guo Y, Zhao S, Su PF, Li CI, Ye F, Flynn CR, Shyr Y.
PMID: 25258704
Transl Cancer Res. 2014 Jun 01;3(3):260-265. doi: 10.3978/j.issn.2218-676X.2014.06.05.

RNAseq technology is replacing microarray technology as the tool of choice for gene expression profiling. While providing much richer data than microarray, analysis of RNAseq data has been much more challenging. Among the many difficulties of RNAseq analysis, correctly...

Analyzing Spatial Heterogeneity in DCE- and DW-MRI Parametric Maps to Optimize Prediction of Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer.

Translational oncology

Li X, Kang H, Arlinghaus LR, Abramson RG, Chakravarthy AB, Abramson VG, Farley J, Sanders M, Yankeelov TE.
PMID: 24772203
Transl Oncol. 2014 Feb 01;7(1):14-22. doi: 10.1593/tlo.13748. eCollection 2014 Feb.

The purpose of this study is to investigate the ability of multivariate analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted MRI (DW-MRI) parametric maps, obtained early in the course of therapy, to predict which patients will achieve...

Emerging targets in pancreatic cancer: epithelial-mesenchymal transition and cancer stem cells.

OncoTargets and therapy

Castellanos JA, Merchant NB, Nagathihalli NS.
PMID: 24049451
Onco Targets Ther. 2013 Sep 13;6:1261-7. doi: 10.2147/OTT.S34670.

Pancreatic ductal adenocarcinoma is one of the most aggressive solid malignancies and is characterized by poor response to current therapy and a dismal survival rate. Recent insights regarding the role of cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT)...

Loss of ACVRIB leads to increased squamous cell carcinoma aggressiveness through alterations in cell-cell and cell-matrix adhesion proteins.

American journal of cancer research

Loomans HA, Arnold SA, Hebron K, Taylor CJ, Zijlstra A, Andl CD.
PMID: 29312797
Am J Cancer Res. 2017 Dec 01;7(12):2422-2437. eCollection 2017.

Squamous cell carcinomas of the head and neck (HNSCC) and esophagus (ESCC) pose a global public health issue due to high mortality rates. Unfortunately, little progress has been made in improving patient outcomes. This is partially a result of...

Integrating Foundational Sciences in a Clinical Context in the Post-Clerkship Curriculum.

Medical science educator

Dahlman KB, Weinger MB, Lomis KD, Nanney L, Osheroff N, Moore DE, Estrada L, Cutrer WB.
PMID: 29632705
Med Sci Educ. 2018 Mar;28(1):145-154. Epub 2018 Jan 02.

PURPOSE: To design, implement, and launch courses that integrate foundational science learning and clinical application in a post-clerkship undergraduate medical school curriculum.METHOD: In Academic Year (AY) 15-16, as part of a comprehensive curricular revision, Vanderbilt University School of Medicine...

Clinical cancer research : an official journal of the American Association for Cancer Research

Croessmann S, Sheehan JH, Lee KM, Sliwoski G, He J, Nagy R, Riddle D, Mayer IA, Balko JM, Lanman R, Miller VA, Cantley LC, Meiler J, Arteaga CL.
PMID: 29284706
Clin Cancer Res. 2018 Mar 15;24(6):1426-1435. doi: 10.1158/1078-0432.CCR-17-2141. Epub 2017 Dec 28.

No abstract available.

Showing 1 to 12 of 270 entries