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Showing 1 to 12 of 167 entries
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Toxic metal(loid) speciation during weathering of iron sulfide mine tailings under semi-arid climate.

Applied geochemistry : journal of the International Association of Geochemistry and Cosmochemistry

Root RA, Hayes SM, Hammond CM, Maier RM, Chorover J.
PMID: 26549929
Appl Geochem. 2015 Nov 01;62:131-149. doi: 10.1016/j.apgeochem.2015.01.005. Epub 2015 Feb 07.

Toxic metalliferous mine-tailings pose a significant health risk to ecosystems and neighboring communities from wind and water dispersion of particulates containing high concentrations of toxic metal(loid)s (e.g., Pb, As, Zn). Tailings are particularly vulnerable to erosion before vegetative cover...

Home Water Treatment Habits and Effectiveness in a Rural Arizona Community.

Water

Lothrop N, Wilkinson ST, Verhougstraete M, Sugeng A, Loh MM, Klimecki W, Beamer PI.
PMID: 26120482
Water (Basel). 2015;7(3):1217-1231. doi: 10.3390/w7031217.

Drinking water quality in the United States (US) is among the safest in the world. However, many residents, often in rural areas, rely on unregulated private wells or small municipal utilities for water needs. These utilities may violate the...

Adjusting for Urinary Creatinine Overestimates Arsenic Concentrations in Diabetics.

Cardiorenal medicine

Yassine H, Kimzey MJ, Galligan MA, Gandolfi AJ, Stump CS, Lau SS.
PMID: 22493600
Cardiorenal Med. 2012 Feb;2(1):26-32. doi: 10.1159/000334225. Epub 2011 Dec 23.

BACKGROUND/AIMS: Arsenic (As) is linked to insulin resistance in animal studies, but the effect of low-level As exposure on the prevalence of diabetes in humans is uncertain. An optimal method to report inorganic As in humans has not been...

Comparison of paired human nasal and bronchial airway epithelial cell responses to rhinovirus infection and IL-13 treatment.

Clinical and translational medicine

Roberts N, Al Mubarak R, Francisco D, Kraft M, Chu HW.
PMID: 29721720
Clin Transl Med. 2018 May 02;7(1):13. doi: 10.1186/s40169-018-0189-2.

BACKGROUND: Because of its advantage as a minimally invasive procedure, nasal brushings have been increasingly used and proposed as a valuable approach to study lower airway diseases in lieu of bronchial epithelial cells. However, there is limited or conflicting...

Efficacy of a proactive health and safety risk management system in the fire service.

Injury epidemiology

Poplin GS, Griffin S, Pollack Porter K, Mallett J, Hu C, Day-Nash V, Burgess JL.
PMID: 29658098
Inj Epidemiol. 2018 Apr 16;5(1):18. doi: 10.1186/s40621-018-0148-9.

BACKGROUND: This study evaluated the efficacy of a fire department proactive risk management program aimed at reducing firefighter injuries and their associated costs.METHODS: Injury data were collected for the intervention fire department and a contemporary control department. Workers' compensation...

Oxidative weathering decreases bioaccessibility of toxic metal(loid)s in PM.

GeoHealth

Thomas AN, Root RA, Lantz RC, Sáez AE, Chorover J.
PMID: 30338309
Geohealth. 2018 Apr;2(4):118-138. doi: 10.1002/2017GH000118. Epub 2018 Mar 22.

Environmental contamination from legacy mine-waste deposits is a persistent problem due to the long history of hard-rock mining. Sulfide ore deposits can contain elevated levels of toxic metal(loid)s that, when mobilized by weathering upon O

Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy.

Frontiers in neuroscience

Teves JMY, Bhargava V, Kirwan KR, Corenblum MJ, Justiniano R, Wondrak GT, Anandhan A, Flores AJ, Schipper DA, Khalpey Z, Sligh JE, Curiel-Lewandrowski C, Sherman SJ, Madhavan L.
PMID: 29379409
Front Neurosci. 2018 Jan 12;11:737. doi: 10.3389/fnins.2017.00737. eCollection 2017.

The discovery of biomarkers for Parkinson's disease (PD) is challenging due to the heterogeneous nature of this disorder, and a poor correlation between the underlying pathology and the clinically expressed phenotype. An ideal biomarker would inform on PD-relevant pathological...

Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series).

Pulmonary circulation

Ranchoux B, Harvey LD, Ayon RJ, Babicheva A, Bonnet S, Chan SY, Yuan JX, Perez VJ.
PMID: 29283043
Pulm Circ. 2018 Jan-Mar;8(1):2045893217752912. doi: 10.1177/2045893217752912. Epub 2017 Dec 28.

Endothelial dysfunction is a major player in the development and progression of vascular pathology in pulmonary arterial hypertension (PAH), a disease associated with small vessel loss and obstructive vasculopathy that leads to increased pulmonary vascular resistance, subsequent right heart...

Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.

Annals of the American Thoracic Society

Burkes RM, Gassett AJ, Ceppe AS, Anderson W, O'Neal WK, Woodruff PG, Krishnan JA, Barr RG, Han MK, Martinez FJ, Comellas AP, Lambert AA, Kaufman JD, Dransfield MT, Wells JM, Kanner RE, Paine R, Bleecker ER, Paulin LM, Hansel NN, Drummond MB.
PMID: 29584453
Ann Am Thorac Soc. 2018 Jul;15(7):808-816. doi: 10.1513/AnnalsATS.201710-837OC.

No abstract available.

Epigenetic Silencing of .

Journal of breast cancer

Vrba L, Futscher BW.
PMID: 28690657
J Breast Cancer. 2017 Jun;20(2):198-202. doi: 10.4048/jbc.2017.20.2.198. Epub 2017 Jun 26.

Immortality is an essential characteristic of cancer cells; a recent transcriptomic study of epithelial cell immortalization has linked epigenetic silencing of the long noncoding RNA

EXPRESS: Surfing the Right Ventricular Pressure Waveform: Methods to assess Global, Systolic and Diastolic RV Function from a Clinical Right Heart Catheterization.

Pulmonary circulation

Vanderpool RR, Puri R, Osorio A, Wickstrom K, Desai A, Black S, Garcia JGN, Yuan J, Rischard F.
PMID: 31032737
Pulm Circ. 2019 Apr 29;2045894019850993. doi: 10.1177/2045894019850993. Epub 2019 Apr 29.

No abstract available.

NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice.

Aging and disease

Anandhan A, Nguyen N, Syal A, Dreher LA, Dodson M, Zhang DD, Madhavan L.
PMID: 34221542
Aging Dis. 2021 Jul 01;12(4):964-982. doi: 10.14336/AD.2021.0511. eCollection 2021 Jul.

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a central regulator of cellular stress responses and its transcriptional activation promotes multiple cellular defense and survival mechanisms. The loss of NRF2 has been shown to increase oxidative and proteotoxic stress, two...

Showing 1 to 12 of 167 entries