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Showing 1 to 12 of 235 entries
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Global DNA Methylation, Measured by the Luminometric Methylation Assay (LUMA), Associates with Postmenopausal Breast Cancer in Non-Obese and Physically Active Women.

Journal of Cancer

McCullough LE, Chen J, White AJ, Xu X, Cho YH, Bradshaw PT, Eng SM, Teitelbaum SL, Terry MB, Garbowski G, Neugut AI, Hibshoosh H, Santella RM, Gammon MD.
PMID: 26000047
J Cancer. 2015 May 01;6(6):548-54. doi: 10.7150/jca.11359. eCollection 2015.

INTRODUCTION: Little is known about how modifiable lifestyle factors interact with the epigenome to influence disease. Body mass index (BMI, weight kg/height m2) and physical activity are associated with postmenopausal breast cancer, but the mechanisms are not well-understood. We...

Lactational Exposure to Polybrominated Diphenyl Ethers and Its Relation to Early Childhood Anthropometric Measurements.

Environmental health perspectives

Hoffman K, Mendez M, Siega-Riz AM, Herring AH, Sjödin A, Daniels JL.
PMID: 27153456
Environ Health Perspect. 2016 Oct;124(10):1656-1661. doi: 10.1289/EHP201. Epub 2016 May 06.

BACKGROUND: Polybrominated diphenyl ethers (PBDEs) are ubiquitous environmental contaminants that may influence growth and development.OBJECTIVE: We investigated the association between exposure to PBDEs via breast milk and anthropometric measurements in early childhood.METHODS: The Pregnancy Infection and Nutrition (PIN) Babies...

Fluxomics of the eastern oyster for environmental stress studies.

Metabolites

Tikunov AP, Stoskopf MK, Macdonald JM.
PMID: 24958387
Metabolites. 2014 Jan 07;4(1):53-70. doi: 10.3390/metabo4010053.

The metabolism of 2-13C/15N-glycine and U-13C-glucose was determined in four tissue blocks (adductor muscle, stomach and digestive gland, mantle, and gills) of the Eastern oyster (Crassostrea virginica) using proton (1H) and carbon-13 (13C) nuclear magnetic resonance (NMR) spectroscopy. The...

Regionalized PM2.5 Community Multiscale Air Quality model performance evaluation across a continuous spatiotemporal domain.

Atmospheric environment (Oxford, England : 1994)

Reyes JM, Xu Y, Vizuete W, Serre ML.
PMID: 28848374
Atmos Environ (1994). 2017 Jan;148:258-265. doi: 10.1016/j.atmosenv.2016.10.048.

The regulatory Community Multiscale Air Quality (CMAQ) model is a means to understanding the sources, concentrations and regulatory attainment of air pollutants within a model's domain. Substantial resources are allocated to the evaluation of model performance. The Regionalized Air...

On negative outcome control of unobserved confounding as a generalization of difference-in-differences.

Statistical science : a review journal of the Institute of Mathematical Statistics

Sofer T, Richardson DB, Colicino E, Schwartz J, Tchetgen Tchetgen EJ.
PMID: 28239233
Stat Sci. 2016;31(3):348-361. doi: 10.1214/16-STS558. Epub 2016 Sep 27.

The

Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury.

Genes

Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC.
PMID: 24921406
Genes (Basel). 2014 Jun 11;5(2):477-96. doi: 10.3390/genes5020477.

Imprinted genes defy rules of Mendelian genetics with their expression tied to the parent from whom each allele was inherited. They are known to play a role in various diseases/disorders including fetal growth disruption, lower birth weight, obesity, and...

Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss.

Gastrointestinal cancer : targets and therapy

Sendor AB, Hacker KE, Chen S, Corona AL, Sen O, Chiang DY, Snavely A, Rogers AB, Montgomery SA, Rathmell WK, McRee AJ.
PMID: 25844041
Gastrointest Cancer. 2015 Feb 01;5:61-71. doi: 10.2147/GICTT.S72274.

No abstract available.

Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive Breast Cancer Associates with Postmenopausal Body Size and Recreational Physical Activity.

International journal of cancer and clinical research

McCullough LE, Chen J, White AJ, Xu X, Cho YH, Bradshaw PT, Eng SM, Teitelbaum SL, Terry MB, Garbowski G, Neugut AI, Hibshoosh H, Santella RM, Gammon MD.
PMID: 26005715
Int J Cancer Clin Res. 2015;2(1). doi: 10.23937/2378-3419/2/1/1013.

INTRODUCTION: Breast cancer, the leading cancer diagnosis among American women, is positively associated with postmenopausal obesity and little or no recreational physical activity (RPA). However, the underlying mechanisms of these associations remain unresolved. Aberrant changes in DNA methylation may...

Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS).

BMC bioinformatics

Staab JM, O'Connell TM, Gomez SM.
PMID: 20214818
BMC Bioinformatics. 2010 Mar 09;11:123. doi: 10.1186/1471-2105-11-123.

BACKGROUND: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentrations or profiles in response to perturbation through disease, toxicants or drugs. The spectra...

Developing measures on the perceptions of the built environment for physical activity: a confirmatory analysis.

The international journal of behavioral nutrition and physical activity

Gay JL, Evenson KR, Smith J.
PMID: 20929571
Int J Behav Nutr Phys Act. 2010 Oct 07;7:72. doi: 10.1186/1479-5868-7-72.

BACKGROUND: Minimal validity evidence exists for scales assessing the built environment for physical activity. The purpose of this study was to assess the test-retest reliability and invariance of a three-factor model (Neighborhood Characteristics, Safety/Crime, and Access to Physical Activity...

Penalized Estimating Functions and Variable Selection in Semiparametric Regression Models.

Journal of the American Statistical Association

Johnson BA, Lin DY, Zeng D.
PMID: 20376193
J Am Stat Assoc. 2008 Jun 01;103(482):672-680. doi: 10.1198/016214508000000184.

We propose a general strategy for variable selection in semiparametric regression models by penalizing appropriate estimating functions. Important applications include semiparametric linear regression with censored responses and semiparametric regression with missing predictors. Unlike the existing penalized maximum likelihood estimators,...

The case-only independence assumption: associations between genetic polymorphisms and smoking among controls in two population-based studies.

International journal of molecular epidemiology and genetics

Hodgson ME, Olshan AF, North KE, Poole CL, Zeng D, Tse CK, Keku TO, Galanko J, Sandler R, Millikan RC.
PMID: 23205185
Int J Mol Epidemiol Genet. 2012;3(4):333-60. Epub 2012 Nov 15.

The independence assumption for a case-only analysis of statistical interaction, i. e. that genetic (G) and environmental exposures (E) are not associated in the source population, is often checked in surrogate populations. Few studies have examined G-E association in...

Showing 1 to 12 of 235 entries