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Showing 1 to 12 of 38 entries
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Effect of particle emissions from biofuel combustion on surface activity of model and therapeutic pulmonary surfactants.

Environmental toxicology and pharmacology

Kanishtha T, Banerjee R, Venkataraman C.
PMID: 21783727
Environ Toxicol Pharmacol. 2006 Nov;22(3):325-33. doi: 10.1016/j.etap.2006.05.003. Epub 2006 May 19.

This study was designed to determine the effects of particle emissions from biofuel combustion in household cooking devices, commonly used in rural India, on surface activity of model lung surfactants using Langmuir monolayers. The effect of wood and dried...

Transient intubation for surfactant administration in the treatment of respiratory distress syndrome in extremely premature infants.

Korean journal of pediatrics

Koh JW, Kim JW, Chang YP.
PMID: 30304909
Korean J Pediatr. 2018 Oct;61(10):315-321. doi: 10.3345/kjp.2018.06296. Epub 2018 Sep 16.

PURPOSE: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants.METHODS:...

Assessment of intrahepatic cholestasis in pregnancy and the effect of disease severity on transient tachypnea in the newborn in uncomplicated fetuses.

Journal of perinatal medicine

Madendağ Y, Sahin E, Col Madendag I, Eraslan Sahin M.
PMID: 34280960
J Perinat Med. 2021 Jul 20;50(1):87-92. doi: 10.1515/jpm-2021-0003. Print 2022 Jan 27.

OBJECTIVES: Considering the effects of bile-acid levels on fetal lungs and pulmonary surfactants, we hypothesized that in the presence of intrahepatic pregnancy cholestasis (ICP), poor neonatal respiratory problems are observed in relation to the severity of the disease. Delivery...

mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury.

JCI insight

Lee H, Fei Q, Streicher A, Zhang W, Isabelle C, Patel P, Lam HC, Arciniegas-Rubio A, Pinilla-Vera M, Amador-Munoz DP, Barragan-Bradford D, Higuera-Moreno A, Putman RK, Sholl LM, Henske EP, Bobba CM, Higuita-Castro N, Shalosky EM, Hite RD, Christman JW, Ghadiali SN, Baron RM, Englert JA.
PMID: 34138757
JCI Insight. 2021 Jul 22;6(14). doi: 10.1172/jci.insight.137708.

The acute respiratory distress syndrome (ARDS) is a highly lethal condition that impairs lung function and causes respiratory failure. Mechanical ventilation (MV) maintains gas exchange in patients with ARDS but exposes lung cells to physical forces that exacerbate injury....

The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19.

Frontiers in pharmacology

Wang S, Li Z, Wang X, Zhang S, Gao P, Shi Z.
PMID: 34267664
Front Pharmacol. 2021 Jun 29;12:698905. doi: 10.3389/fphar.2021.698905. eCollection 2021.

Lung alveolar type-II (AT-II) cells produce pulmonary surfactant (PS), consisting of proteins and lipids. The lipids in PS are primarily responsible for reducing the air-fluid surface tension inside the alveoli of the lungs and to prevent atelectasis. The proteins...

GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.

Science China. Life sciences

Pang Q, Liu C, Qiao Y, Zhao J, Lam SM, Mei M, Shui G, Bao S, Li Q.
PMID: 33740186
Sci China Life Sci. 2022 Jan;65(1):193-205. doi: 10.1007/s11427-020-1875-x. Epub 2021 Mar 16.

Pulmonary surfactant is a lipid-protein complex secreted by alveolar type II epithelial cells and is essential for the maintenance of the delicate structure of mammalian alveoli to promote efficient gas exchange across the air-liquid barrier. The Golgi apparatus plays...

Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome.

JCI insight

Rizzo AN, Haeger SM, Oshima K, Yang Y, Wallbank AM, Jin Y, Lettau M, McCaig LA, Wickersham NE, McNeil JB, Zakharevich I, McMurtry SA, Langouët-Astrié CJ, Kopf KW, Voelker DR, Hansen KC, Shaver CM, Kerchberger VE, Peterson RA, Kuebler WM, Ochs M, Veldhuizen RA, Smith BJ, Ware LB, Bastarache JA, Schmidt EP.
PMID: 34874923
JCI Insight. 2021 Dec 07; doi: 10.1172/jci.insight.154573. Epub 2021 Dec 07.

Acute Respiratory Distress Syndrome (ARDS) is a common cause of respiratory failure yet has few pharmacologic therapies, reflecting the mechanistic heterogeneity of lung injury. We hypothesized that damage to the alveolar epithelial glycocalyx, a layer of glycosaminoglycans interposed between...

Laryngeal Mask Airway for Surfactant Administration Versus Standard Treatment Methods in Preterm Neonates with Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis.

American journal of perinatology

Al Ali RA, Gautam B, Miller MR, Coulson S, Yuen D.
PMID: 33517565
Am J Perinatol. 2021 Jan 31; doi: 10.1055/s-0041-1722953. Epub 2021 Jan 31.

OBJECTIVE:  Laryngeal mask airway (LMA) has emerged as an alternative surfactant delivery method. The effectiveness of this method for the delivery of surfactant is uncertain. A meta-analysis of randomized control trials (RCTs) comparing LMA with standard methods of surfactant...

Hypoxia-mediated alterations in pulmonary surfactant protein expressions: Beneficial effects of quercetin prophylaxis.

Respiratory physiology & neurobiology

Tripathi A, Kumar B, Sagi SSK.
PMID: 34052411
Respir Physiol Neurobiol. 2021 Sep;291:103695. doi: 10.1016/j.resp.2021.103695. Epub 2021 May 27.

We have compared the prophylactic efficacies of quercetin and salbutamol in preventing pulmonary surfactants oxidation under hypoxia. Male SD rats supplemented orally with quercetin (50 mg/Kg BW) and salbutamol (2 mg/Kg BW) were exposed to hypobaric hypoxia (7,620 m...

Drug Meets Monolayer: Understanding the Interactions of Sterol Drugs with Models of the Lung Surfactant Monolayer Using Molecular Dynamics Simulations.

Methods in molecular biology (Clifton, N.J.)

Hossain SI, Islam MZ, Saha SC, Deplazes E.
PMID: 34854039
Methods Mol Biol. 2022;2402:103-121. doi: 10.1007/978-1-0716-1843-1_9.

The lung surfactant monolayer (LSM) is a thin layer of lipids and proteins that forms the air/water interface of the alveoli. The primary function of the LSM is to reduce the surface tension at the air/water interface during breathing....

Assessment of intrahepatic cholestasis in pregnancy and the effect of disease severity on transient tachypnea in the newborn in uncomplicated fetuses.

Journal of perinatal medicine

Madendağ Y, Sahin E, Col Madendag I, Eraslan Sahin M.
PMID: 34280960
J Perinat Med. 2021 Jul 20; doi: 10.1515/jpm-2021-0003. Epub 2021 Jul 20.

OBJECTIVES: Considering the effects of bile-acid levels on fetal lungs and pulmonary surfactants, we hypothesized that in the presence of intrahepatic pregnancy cholestasis (ICP), poor neonatal respiratory problems are observed in relation to the severity of the disease. Delivery...

High Flow Nasal Cannulae versus Nasal Continuous Positive Airway Pressure in Neonates with Respiratory Distress Syndrome Managed with INSURE Method: A Randomized Clinical Trial.

Iranian journal of medical sciences

Kadivar M, Mosayebi Z, Razi N, Nariman S, Sangsari R.
PMID: 27853329
Iran J Med Sci. 2016 Nov;41(6):494-500.

BACKGROUND: In recent years, various noninvasive respiratory support (NRS) of ventilation has been provided more in neonates. The aim of this study was to compare the effect of HFNC with NCPAP in post-extubation of preterm infants with RDS after...

Showing 1 to 12 of 38 entries