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Showing 1 to 8 of 8 entries
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Nuclear expression of PG-21, SRC-1, and pCREB in regions of the lumbosacral spinal cord involved in pelvic innervation in young adult and aged rats.

Anatomy & cell biology

Ranson RN, Connelly JH, Santer RM, Watson AH.
PMID: 23301192
Anat Cell Biol. 2012 Dec;45(4):241-58. doi: 10.5115/acb.2012.45.4.241. Epub 2012 Dec 14.

In rats, ageing results in dysfunctional patterns of micturition and diminished sexual reflexes that may reflect degenerative changes within spinal circuitry. In both sexes the dorsal lateral nucleus and the spinal nucleus of the bulbospongiosus, which lie in the...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 21;55(24):16552-16562. doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Growth factor receptors and apoptosis regulators: signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer.

Breast cancer : basic and clinical research

Sarkar S, Mandal M.
PMID: 21556249
Breast Cancer (Auckl). 2009 Aug 17;3:47-60. doi: 10.4137/bcbcr.s2492.

Biomarkers of breast cancer are necessary for prognosis and prediction to chemotherapy. Prognostic biomarkers provide information regarding outcome irrespective of therapy, while predictive biomarkers provide information regarding response to therapy. Candidate prognostic biomarkers for breast cancers are growth factor...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 21;55(24):16552-16562. doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Inhalational Anesthesia for Near-fatal Pediatric Asthma Complicated by Malignant Hyperthermia.

Cureus

Pasrija D, Assioun J, Sallam M, Prout A.
PMID: 34824940
Cureus. 2021 Oct 25;13(10):e19032. doi: 10.7759/cureus.19032. eCollection 2021 Oct.

Acute severe asthma is a commonly encountered condition in the pediatric emergency room and the pediatric intensive care unit (PICU). Its treatment involves the use of bronchodilatory agents acting on different receptors, steroids to reduce ongoing inflammation, and non-invasive...

Distinct actions of ancestral vinclozolin and juvenile stress on neural gene expression in the male rat.

Frontiers in genetics

Gillette R, Miller-Crews I, Skinner MK, Crews D.
PMID: 25784924
Front Genet. 2015 Mar 02;6:56. doi: 10.3389/fgene.2015.00056. eCollection 2015.

Exposure to the endocrine disrupting chemical vinclozolin during gestation of an F0 generation and/or chronic restraint stress during adolescence of the F3 descendants affects behavior, physiology, and gene expression in the brain. Genes related to the networks of growth...

Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates peroxisome proliferator-activated receptor gamma in type 2 diabetic rats.

The Journal of pharmacy and pharmacology

Allam MAM, Khowailed AA, Elattar S, Mahmoud AM.
PMID: 34156072
J Pharm Pharmacol. 2021 Jun 22; doi: 10.1093/jpp/rgab083. Epub 2021 Jun 22.

OBJECTIVES: Diabetes mellitus (DM) is a chronic disease associated with serious complications, including male infertility. Umbelliferone (UMB) is a coumarin with promising antioxidant, anti-inflammatory and other beneficial effects. This study investigated the ameliorative effect of UMB against testicular injury,...

Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.

Environmental science & technology

Tan H, Chen Q, Hong H, Benfenati E, Gini GC, Zhang X, Yu H, Shi W.
PMID: 34859678
Environ Sci Technol. 2021 Dec 03; doi: 10.1021/acs.est.1c04997. Epub 2021 Dec 03.

Endocrine-disrupting chemicals (EDCs) can inadvertently interact with 12 classic nuclear receptors (NRs) that disrupt the endocrine system and cause adverse effects. There is no widely accepted understanding about what structural features make thousands of EDCs able to activate different...

Showing 1 to 8 of 8 entries