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Identifying an Allosteric Switch Region in Human SIRT1

Louis Stokes Alliances for Minority Participation AND Program Evaluation

[No authors listed]
GSID: zaYZh8hk3m4J
A Huynh, CA Amaya, S Montermoso… - The FASEB …, 2019 - Wiley Online Library

SIRT1 is an NAD+‐dependent lysine deacetylase that is implicated in age‐related diseases and is a potential therapeutic target for drug development. The N‐terminal domain is highly disordered and is usually removed prior to crystallization of the enzyme. However, it...

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Huynh, A., Amaya, C. A., Montermoso, S., Lustig, B., & Wang, N. (2019). Identifying an Allosteric Switch Region in Human SIRT1. The FASEB Journal, 33(S1), lb222-lb222.
Huynh, Angelina, et al. "Identifying an Allosteric Switch Region in Human SIRT1." The FASEB Journal 33.S1 (2019): lb222-lb222.
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Jasmonates elicit different sets of stilbenes in Vitis vinifera cv. Negramaro cell cultures.

SpringerPlus

Taurino M, Ingrosso I, D'amico L, De Domenico S, Nicoletti I, Corradini D, Santino A, Giovinazzo G.
PMID: 25674504
Springerplus. 2015 Feb 01;4:49. doi: 10.1186/s40064-015-0831-z. eCollection 2015.

The plant phenol trans-resveratrol, which is mainly found in grape, displays a wide range of biological effects. A cell suspension culture was developed from calli of grape leaves of Vitis vinifera cv. Negramaro in order to study the bioproduction...

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Taurino M, Ingrosso I, D'amico L, et al. Jasmonates elicit different sets of stilbenes in Vitis vinifera cv. Negramaro cell cultures. Springerplus. 2015;4:49doi: 10.1186/s40064-015-0831-z.
Taurino, M., Ingrosso, I., D'amico, L., De Domenico, S., Nicoletti, I., Corradini, D., Santino, A., & Giovinazzo, G. (2015). Jasmonates elicit different sets of stilbenes in Vitis vinifera cv. Negramaro cell cultures. SpringerPlus, 449. https://doi.org/10.1186/s40064-015-0831-z
Taurino, Marco, et al. "Jasmonates elicit different sets of stilbenes in Vitis vinifera cv. Negramaro cell cultures." SpringerPlus vol. 4 (2015): 49. doi: https://doi.org/10.1186/s40064-015-0831-z
Taurino M, Ingrosso I, D'amico L, De Domenico S, Nicoletti I, Corradini D, Santino A, Giovinazzo G. Jasmonates elicit different sets of stilbenes in Vitis vinifera cv. Negramaro cell cultures. Springerplus. 2015 Feb 01;4:49. doi: 10.1186/s40064-015-0831-z. eCollection 2015. PMID: 25674504; PMCID: PMC4320690.
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TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma.

Oncotarget

Piao L, Mukherjee S, Chang Q, Xie X, Li H, Castellanos MR, Banerjee P, Iqbal H, Ivancic R, Wang X, Teknos TN, Pan Q.
PMID: 28947951
Oncotarget. 2016 Jul 16;8(36):60025-60035. doi: 10.18632/oncotarget.10620. eCollection 2017 Sep 01.

Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide with about 600,000 new cases diagnosed in the last year. The incidence of human papillomavirus-positive head and neck squamous cell carcinoma (HPV-positive HNSCC) has rapidly...

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Piao L, Mukherjee S, Chang Q, et al. TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma. Oncotarget. 2016;8(36):60025-60035doi: 10.18632/oncotarget.10620.
Piao, L., Mukherjee, S., Chang, Q., Xie, X., Li, H., Castellanos, M. R., Banerjee, P., Iqbal, H., Ivancic, R., Wang, X., Teknos, T. N., & Pan, Q. (2017). TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma. Oncotarget, 8(36), 60025-60035. https://doi.org/10.18632/oncotarget.10620
Piao, Longzhu, et al. "TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma." Oncotarget vol. 8,36 (2017): 60025-60035. doi: https://doi.org/10.18632/oncotarget.10620
Piao L, Mukherjee S, Chang Q, Xie X, Li H, Castellanos MR, Banerjee P, Iqbal H, Ivancic R, Wang X, Teknos TN, Pan Q. TriCurin, a novel formulation of curcumin, epicatechin gallate, and resveratrol, inhibits the tumorigenicity of human papillomavirus-positive head and neck squamous cell carcinoma. Oncotarget. 2016 Jul 16;8(36):60025-60035. doi: 10.18632/oncotarget.10620. eCollection 2017 Sep 01. PMID: 28947951; PMCID: PMC5601119.
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Caragaphenol a induces reactive oxygen species related apoptosis in human gastric cancer cells.

American journal of translational research

Peng QQ, Wang K, Cheng KJ, Yang HG, Qiu JG, Zhang WJ, Jiang QW, Yang Y, Zheng DW, Huang JR, Wei MN, Shi Z, Wang W.
PMID: 28861171
Am J Transl Res. 2017 Aug 15;9(8):3804-3815. eCollection 2017.

Caragaphenol A (CAA) is a novel resveratrol trimer isolated from the roots of Caraganastenophylla. However, the biological activity of CAA is still unknown. In the present study, we investigated the anticancer effects of CAA on gastric cancer cells. CAA...

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Peng QQ, Wang K, Cheng KJ, et al. Caragaphenol a induces reactive oxygen species related apoptosis in human gastric cancer cells. Am J Transl Res. 2017;9(8):3804-3815
Peng, Q. Q., Wang, K., Cheng, K. J., Yang, H. G., Qiu, J. G., Zhang, W. J., Jiang, Q. W., Yang, Y., Zheng, D. W., Huang, J. R., Wei, M. N., Shi, Z., & Wang, W. (2017). Caragaphenol a induces reactive oxygen species related apoptosis in human gastric cancer cells. American journal of translational research, 9(8), 3804-3815.
Peng, Qi-Qi, et al. "Caragaphenol a induces reactive oxygen species related apoptosis in human gastric cancer cells." American journal of translational research vol. 9,8 (2017): 3804-3815.
Peng QQ, Wang K, Cheng KJ, Yang HG, Qiu JG, Zhang WJ, Jiang QW, Yang Y, Zheng DW, Huang JR, Wei MN, Shi Z, Wang W. Caragaphenol a induces reactive oxygen species related apoptosis in human gastric cancer cells. Am J Transl Res. 2017 Aug 15;9(8):3804-3815. eCollection 2017. PMID: 28861171; PMCID: PMC5575194.
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Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.).

Endocrinology and metabolism (Seoul, Korea)

Ku CR, Lee EJ.
PMID: 27704742
Endocrinol Metab (Seoul). 2016 Sep;31(3):482-483. doi: 10.3803/EnM.2016.31.3.482.

No abstract available.

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Ku CR, Lee EJ. Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.). Endocrinol Metab (Seoul). 2016;31(3):482-483doi: 10.3803/EnM.2016.31.3.482.
Ku, C. R., & Lee, E. J. (2016). Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.). Endocrinology and metabolism (Seoul, Korea), 31(3), 482-483. https://doi.org/10.3803/EnM.2016.31.3.482
Ku, Cheol Ryong, and Lee, Eun Jig. "Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.)." Endocrinology and metabolism (Seoul, Korea) vol. 31,3 (2016): 482-483. doi: https://doi.org/10.3803/EnM.2016.31.3.482
Ku CR, Lee EJ. Response: The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes (Endocrinol Metab 2016;31:328-35, Cheol Ryong Ku et al.). Endocrinol Metab (Seoul). 2016 Sep;31(3):482-483. doi: 10.3803/EnM.2016.31.3.482. PMID: 27704742; PMCID: PMC5053064.
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Prostate cancer: Resveratrol inhibits the AR.

Nature reviews. Urology

Fenner A.
PMID: 28976500
Nat Rev Urol. 2017 Nov;14(11):642. doi: 10.1038/nrurol.2017.159. Epub 2017 Oct 04.

No abstract available.

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Fenner A. Prostate cancer: Resveratrol inhibits the AR. Nat Rev Urol. 2017;14(11):642doi: 10.1038/nrurol.2017.159.
Fenner, A. (2017). Prostate cancer: Resveratrol inhibits the AR. Nature reviews. Urology, 14(11), 642. https://doi.org/10.1038/nrurol.2017.159
Fenner, Annette. "Prostate cancer: Resveratrol inhibits the AR." Nature reviews. Urology vol. 14,11 (2017): 642. doi: https://doi.org/10.1038/nrurol.2017.159
Fenner A. Prostate cancer: Resveratrol inhibits the AR. Nat Rev Urol. 2017 Nov;14(11):642. doi: 10.1038/nrurol.2017.159. Epub 2017 Oct 04. PMID: 28976500.
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Synthesis of acid-degradable hyperbranched poly(resveratrol-co-ketal)-b-mPEG nanoparticles.

Journal of controlled release : official journal of the Controlled Release Society

Han B, Ma F, Zou X, Li Z.
PMID: 27005061
J Control Release. 2015 Sep 10;213:e12. doi: 10.1016/j.jconrel.2015.05.016. Epub 2015 Aug 19.

No abstract available.

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Han B, Ma F, Zou X, et al. Synthesis of acid-degradable hyperbranched poly(resveratrol-co-ketal)-b-mPEG nanoparticles. J Control Release. 2015;213:e12doi: 10.1016/j.jconrel.2015.05.016.
Han, B., Ma, F., Zou, X., & Li, Z. (2015). Synthesis of acid-degradable hyperbranched poly(resveratrol-co-ketal)-b-mPEG nanoparticles. Journal of controlled release : official journal of the Controlled Release Society, 213e12. https://doi.org/10.1016/j.jconrel.2015.05.016
Han, Bo, et al. "Synthesis of acid-degradable hyperbranched poly(resveratrol-co-ketal)-b-mPEG nanoparticles." Journal of controlled release : official journal of the Controlled Release Society vol. 213 (2015): e12. doi: https://doi.org/10.1016/j.jconrel.2015.05.016
Han B, Ma F, Zou X, Li Z. Synthesis of acid-degradable hyperbranched poly(resveratrol-co-ketal)-b-mPEG nanoparticles. J Control Release. 2015 Sep 10;213:e12. doi: 10.1016/j.jconrel.2015.05.016. Epub 2015 Aug 19. PMID: 27005061.
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Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells.

International journal of oncology

Mikami S, Ota I, Masui T, Itaya-Hironaka A, Shobatake R, Okamoto H, Takasawa S, Kitahara T.
PMID: 27633858
Int J Oncol. 2016 Oct;49(4):1553-1560. doi: 10.3892/ijo.2016.3664. Epub 2016 Aug 19.

Identification of reliable markers of chemo- and radiosensitivity and the key molecules that enhance the susceptibility of head and neck squamous cell carcinoma (HNSCC) to anticancer treatments is highly desirable. Previously, we have reported that regenerating gene (REG) Ⅲ...

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Mikami S, Ota I, Masui T, et al. Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells. Int J Oncol. 2016;49(4):1553-1560doi: 10.3892/ijo.2016.3664.
Mikami, S., Ota, I., Masui, T., Itaya-Hironaka, A., Shobatake, R., Okamoto, H., Takasawa, S., & Kitahara, T. (2016). Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells. International journal of oncology, 49(4), 1553-1560. https://doi.org/10.3892/ijo.2016.3664
Mikami, Shinji, et al. "Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells." International journal of oncology vol. 49,4 (2016): 1553-1560. doi: https://doi.org/10.3892/ijo.2016.3664
Mikami S, Ota I, Masui T, Itaya-Hironaka A, Shobatake R, Okamoto H, Takasawa S, Kitahara T. Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells. Int J Oncol. 2016 Oct;49(4):1553-1560. doi: 10.3892/ijo.2016.3664. Epub 2016 Aug 19. PMID: 27633858.
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The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice.

Gastroenterology research and practice

Zhou Y, Chen K, He L, Xia Y, Dai W, Wang F, Li J, Li S, Liu T, Zheng Y, Wang J, Lu W, Yin Q, Zhou Y, Lu J, Teng H, Guo C.
PMID: 26089871
Gastroenterol Res Pract. 2015;2015:506390. doi: 10.1155/2015/506390. Epub 2015 May 24.

Pharmacologic Relevance. Resveratrol, an antioxidant derived from grapes, has been reported to modulate the inflammatory process. In this study, we investigated the effects of resveratrol and its mechanism of protection on concanavalin-A- (ConA-) induced liver injury in mice. Materials...

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Zhou Y, Chen K, He L, et al. The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice. Gastroenterol Res Pract. 2015;2015:506390doi: 10.1155/2015/506390.
Zhou, Y., Chen, K., He, L., Xia, Y., Dai, W., Wang, F., Li, J., Li, S., Liu, T., Zheng, Y., Wang, J., Lu, W., Yin, Q., Zhou, Y., Lu, J., Teng, H., & Guo, C. (2015). The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice. Gastroenterology research and practice, 2015506390. https://doi.org/10.1155/2015/506390
Zhou, Yingqun, et al. "The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice." Gastroenterology research and practice vol. 2015 (2015): 506390. doi: https://doi.org/10.1155/2015/506390
Zhou Y, Chen K, He L, Xia Y, Dai W, Wang F, Li J, Li S, Liu T, Zheng Y, Wang J, Lu W, Yin Q, Zhou Y, Lu J, Teng H, Guo C. The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice. Gastroenterol Res Pract. 2015;2015:506390. doi: 10.1155/2015/506390. Epub 2015 May 24. PMID: 26089871; PMCID: PMC4458299.
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Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures.

Beilstein journal of organic chemistry

Trollope L, Cruickshank DL, Noonan T, Bourne SA, Sorrenti M, Catenacci L, Caira MR.
PMID: 25670983
Beilstein J Org Chem. 2014 Dec 29;10:3136-51. doi: 10.3762/bjoc.10.331. eCollection 2014.

The phytoalexin trans-resveratrol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, is a well-known, potent antioxidant having a variety of possible biomedical applications. However, its adverse physicochemical properties (low stability, poor aqueous solubility) limit such applications and its inclusion in cyclodextrins (CDs) has potential for addressing...

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Trollope L, Cruickshank DL, Noonan T, et al. Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures. Beilstein J Org Chem. 2014;10:3136-51doi: 10.3762/bjoc.10.331.
Trollope, L., Cruickshank, D. L., Noonan, T., Bourne, S. A., Sorrenti, M., Catenacci, L., & Caira, M. R. (2014). Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures. Beilstein journal of organic chemistry, 103136-51. https://doi.org/10.3762/bjoc.10.331
Trollope, Lee, et al. "Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures." Beilstein journal of organic chemistry vol. 10 (2014): 3136-51. doi: https://doi.org/10.3762/bjoc.10.331
Trollope L, Cruickshank DL, Noonan T, Bourne SA, Sorrenti M, Catenacci L, Caira MR. Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures. Beilstein J Org Chem. 2014 Dec 29;10:3136-51. doi: 10.3762/bjoc.10.331. eCollection 2014. PMID: 25670983; PMCID: PMC4311586.
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Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats.

Journal of pharmacy & bioallied sciences

Chakraborty S, Pujani M, Haque SE.
PMID: 26229360
J Pharm Bioallied Sci. 2015 Jul-Sep;7(3):233-8. doi: 10.4103/0975-7406.160037.

INTRODUCTION: Resveratrol is a natural polyphenol present mainly in grapes. It has been shown to offer strong cardio protection in animal models due to its ability to correct lipid peroxidation and maintain antioxidants level. Atorvastatin, a HMG-CoA reductase inhibitor,...

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Chakraborty S, Pujani M, Haque SE. Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats. J Pharm Bioallied Sci. 2015;7(3):233-8doi: 10.4103/0975-7406.160037.
Chakraborty, S., Pujani, M., & Haque, S. E. (2015). Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats. Journal of pharmacy & bioallied sciences, 7(3), 233-8. https://doi.org/10.4103/0975-7406.160037
Chakraborty, Songjukta, et al. "Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats." Journal of pharmacy & bioallied sciences vol. 7,3 (2015): 233-8. doi: https://doi.org/10.4103/0975-7406.160037
Chakraborty S, Pujani M, Haque SE. Combinational effect of resveratrol and atorvastatin on isoproterenol-induced cardiac hypertrophy in rats. J Pharm Bioallied Sci. 2015 Jul-Sep;7(3):233-8. doi: 10.4103/0975-7406.160037. PMID: 26229360; PMCID: PMC4517328.
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The effects of either resveratrol or exercise on macrophage infiltration and switching from M1 to M2 in high fat diet mice.

Journal of exercise nutrition & biochemistry

Jeong JH, Lee YR, Park HG, Lee WL.
PMID: 26244124
J Exerc Nutrition Biochem. 2015 Jun;19(2):65-72. doi: 10.5717/jenb.2015.15060203. Epub 2015 Jun 30.

PURPOSE: The aim of this study was to compare the effectiveness of either resveratrol supplementation or exercise training on macrophage infiltration and switching from M1 to M2 kupffer cells in high fat diet mice.METHODS: C57BL/6 mice were separated into...

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Jeong JH, Lee YR, Park HG, et al. The effects of either resveratrol or exercise on macrophage infiltration and switching from M1 to M2 in high fat diet mice. J Exerc Nutrition Biochem. 2015;19(2):65-72doi: 10.5717/jenb.2015.15060203.
Jeong, J. H., Lee, Y. R., Park, H. G., & Lee, W. L. (2015). The effects of either resveratrol or exercise on macrophage infiltration and switching from M1 to M2 in high fat diet mice. Journal of exercise nutrition & biochemistry, 19(2), 65-72. https://doi.org/10.5717/jenb.2015.15060203
Jeong, Jun Hyun, et al. "The effects of either resveratrol or exercise on macrophage infiltration and switching from M1 to M2 in high fat diet mice." Journal of exercise nutrition & biochemistry vol. 19,2 (2015): 65-72. doi: https://doi.org/10.5717/jenb.2015.15060203
Jeong JH, Lee YR, Park HG, Lee WL. The effects of either resveratrol or exercise on macrophage infiltration and switching from M1 to M2 in high fat diet mice. J Exerc Nutrition Biochem. 2015 Jun;19(2):65-72. doi: 10.5717/jenb.2015.15060203. Epub 2015 Jun 30. PMID: 26244124; PMCID: PMC4523807.
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Showing 1 to 12 of 2382 entries