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Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride.

Saudi journal of biological sciences

Al-Rasheed NM, Al-Rasheed NM, Faddah LM, Mohamed AM, Mohammad RA, Al-Amin M.
PMID: 24955012
Saudi J Biol Sci. 2014 Jul;21(3):265-74. doi: 10.1016/j.sjbs.2013.09.006. Epub 2013 Sep 17.

The aim of this study was to investigate the effective role of silymarin either alone or in combination with chlorogenic acid and/or melatonin against the toxic impact of carbon tetrachloride (CCl4) induced cardiac infarction. CCl4 (l.2 ml/kg body weight)...

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Al-Rasheed NM, Al-Rasheed NM, Faddah LM, et al. Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride. Saudi J Biol Sci. 2013;21(3):265-74doi: 10.1016/j.sjbs.2013.09.006.
Al-Rasheed, N. M., Al-Rasheed, N. M., Faddah, L. M., Mohamed, A. M., Mohammad, R. A., & Al-Amin, M. (2014). Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride. Saudi journal of biological sciences, 21(3), 265-74. https://doi.org/10.1016/j.sjbs.2013.09.006
Al-Rasheed, Nouf M, et al. "Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride." Saudi journal of biological sciences vol. 21,3 (2014): 265-74. doi: https://doi.org/10.1016/j.sjbs.2013.09.006
Al-Rasheed NM, Al-Rasheed NM, Faddah LM, Mohamed AM, Mohammad RA, Al-Amin M. Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride. Saudi J Biol Sci. 2014 Jul;21(3):265-74. doi: 10.1016/j.sjbs.2013.09.006. Epub 2013 Sep 17. PMID: 24955012; PMCID: PMC4061402.
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Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats.

Food & nutrition research

Arbab AH, Parvez MK, Al-Dosari MS, Al-Rehaily AJ, Ibrahim KE, Alam P, Alsaid MS, Rafatullah S.
PMID: 27059702
Food Nutr Res. 2016 Apr 07;60:30864. doi: 10.3402/fnr.v60.30864. eCollection 2016.

BACKGROUND: Liver diseases, the fifth most common cause of global death, can be metabolic, toxin-induced, or infective. Though approximately 35 Saudi medicinal plants are traditionally used to treat liver disorders, the hepatoprotective potential of Aerva javanica has not been...

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Arbab AH, Parvez MK, Al-Dosari MS, et al. Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats. Food Nutr Res. 2016;60:30864doi: 10.3402/fnr.v60.30864.
Arbab, A. H., Parvez, M. K., Al-Dosari, M. S., Al-Rehaily, A. J., Ibrahim, K. E., Alam, P., Alsaid, M. S., & Rafatullah, S. (2016). Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats. Food & nutrition research, 6030864. https://doi.org/10.3402/fnr.v60.30864
Arbab, Ahmed H, et al. "Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats." Food & nutrition research vol. 60 (2016): 30864. doi: https://doi.org/10.3402/fnr.v60.30864
Arbab AH, Parvez MK, Al-Dosari MS, Al-Rehaily AJ, Ibrahim KE, Alam P, Alsaid MS, Rafatullah S. Therapeutic efficacy of ethanolic extract of Aerva javanica aerial parts in the amelioration of CCl4-induced hepatotoxicity and oxidative damage in rats. Food Nutr Res. 2016 Apr 07;60:30864. doi: 10.3402/fnr.v60.30864. eCollection 2016. PMID: 27059702; PMCID: PMC4826463.
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Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats.

Antioxidants (Basel, Switzerland)

Singh D, Arya PV, Aggarwal VP, Gupta RS.
PMID: 26785072
Antioxidants (Basel). 2014 Sep 02;3(3):569-91. doi: 10.3390/antiox3030569.

The antioxidant and hepatoprotective activities of the extract of Moringa oleifera leaves were investigated against CCl₄-induced hepatotoxicity in rats. Hepatotoxic rats were treated with ethanol extract of Moringa oleifera for a period of 60 days at the following three...

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Singh D, Arya PV, Aggarwal VP, et al. Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats. Antioxidants (Basel). 2014;3(3):569-91doi: 10.3390/antiox3030569.
Singh, D., Arya, P. V., Aggarwal, V. P., & Gupta, R. S. (2014). Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats. Antioxidants (Basel, Switzerland), 3(3), 569-91. https://doi.org/10.3390/antiox3030569
Singh, Dharmendra, et al. "Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats." Antioxidants (Basel, Switzerland) vol. 3,3 (2014): 569-91. doi: https://doi.org/10.3390/antiox3030569
Singh D, Arya PV, Aggarwal VP, Gupta RS. Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats. Antioxidants (Basel). 2014 Sep 02;3(3):569-91. doi: 10.3390/antiox3030569. PMID: 26785072; PMCID: PMC4665414.
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Evaluation of the effects of the hydroalcoholic extract of .

Avicenna journal of phytomedicine

Ahmadi-Naji R, Heidarian E, Ghatreh-Samani K.
PMID: 29062807
Avicenna J Phytomed. 2017 Sep-Oct;7(5):454-466.

OBJECTIVE: Diazinon causes oxidative stress and dysfunction of the liver. This study was undertaken to evaluate the effects of the hydroalcoholic extract of MATERIALS AND METHODS: Wistar rats were orally administered with 25 mg/kg body weight diazinon. Vehicle (distilled...

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Ahmadi-Naji R, Heidarian E, Ghatreh-Samani K. Evaluation of the effects of the hydroalcoholic extract of . Avicenna J Phytomed. 2017;7(5):454-466
Ahmadi-Naji, R., Heidarian, E., & Ghatreh-Samani, K. (2017). Evaluation of the effects of the hydroalcoholic extract of . Avicenna journal of phytomedicine, 7(5), 454-466.
Ahmadi-Naji, Raheleh, et al. "Evaluation of the effects of the hydroalcoholic extract of ." Avicenna journal of phytomedicine vol. 7,5 (2017): 454-466.
Ahmadi-Naji R, Heidarian E, Ghatreh-Samani K. Evaluation of the effects of the hydroalcoholic extract of . Avicenna J Phytomed. 2017 Sep-Oct;7(5):454-466. PMID: 29062807; PMCID: PMC5641420.
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Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro.

EXCLI journal

Zhao F, Li X.
PMID: 27152106
EXCLI J. 2015 Jul 27;14:861-74. doi: 10.17179/excli2015-257. eCollection 2015.

This study revealed the optimal conditions for the Ultrasonic-Assisted Enzymatic Extraction (UAEE) of silymarin, and include: the concentration of ethanol, 50 %; enzyme concentration, 30 U/mg; liquid-solid ratio, 6:1; an extraction time of 120 min; and the ultrasonic power...

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Zhao F, Li X. Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro. EXCLI J. 2015;14:861-74doi: 10.17179/excli2015-257.
Zhao, F., & Li, X. (2015). Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro. EXCLI journal, 14861-74. https://doi.org/10.17179/excli2015-257
Zhao, Fei, and Li, XinHua. "Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro." EXCLI journal vol. 14 (2015): 861-74. doi: https://doi.org/10.17179/excli2015-257
Zhao F, Li X. Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro. EXCLI J. 2015 Jul 27;14:861-74. doi: 10.17179/excli2015-257. eCollection 2015. PMID: 27152106; PMCID: PMC4849107.
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cis-trans Isomerization of silybins A and B.

Beilstein journal of organic chemistry

Novotná M, Gažák R, Biedermann D, Di Meo F, Marhol P, Kuzma M, Bednárová L, Fuksová K, Trouillas P, Křen V.
PMID: 24991256
Beilstein J Org Chem. 2014 May 08;10:1047-1063. doi: 10.3762/bjoc.10.105. eCollection 2014.

Methods were developed and optimized for the preparation of the 2,3-cis- and the 10,11-cis-isomers of silybin by the Lewis acid catalyzed (BF3∙OEt2) isomerization of silybins A (1a) and B (1b) (trans-isomers). The absolute configuration of all optically pure compounds...

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Novotná M, Gažák R, Biedermann D, et al. cis-trans Isomerization of silybins A and B. Beilstein J Org Chem. 2014;10:1047-1063doi: 10.3762/bjoc.10.105.
Novotná, M., Gažák, R., Biedermann, D., Di Meo, F., Marhol, P., Kuzma, M., Bednárová, L., Fuksová, K., Trouillas, P., & Křen, V. (2014). cis-trans Isomerization of silybins A and B. Beilstein journal of organic chemistry, 101047-1063. https://doi.org/10.3762/bjoc.10.105
Novotná, Michaela, et al. "cis-trans Isomerization of silybins A and B." Beilstein journal of organic chemistry vol. 10 (2014): 1047-1063. doi: https://doi.org/10.3762/bjoc.10.105
Novotná M, Gažák R, Biedermann D, Di Meo F, Marhol P, Kuzma M, Bednárová L, Fuksová K, Trouillas P, Křen V. cis-trans Isomerization of silybins A and B. Beilstein J Org Chem. 2014 May 08;10:1047-1063. doi: 10.3762/bjoc.10.105. eCollection 2014. PMID: 24991256; PMCID: PMC4077359.
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Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Kim EJ, Lee MY, Jeon YJ.
PMID: 25954125
Korean J Physiol Pharmacol. 2015 May;19(3):211-8. doi: 10.4196/kjpp.2015.19.3.211. Epub 2015 Apr 30.

The present study showed that silymarin, a polyphenolic flavonoid isolated from milk thistle (Silybum marianum), inhibited lipopolysaccharide (LPS)-induced morphological changes in the mouse RAW264.7 macrophage cell line. We also showed that silymarin inhibited the nuclear translocation and transactivation activities...

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Kim EJ, Lee MY, Jeon YJ. Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway. Korean J Physiol Pharmacol. 2015;19(3):211-8doi: 10.4196/kjpp.2015.19.3.211.
Kim, E. J., Lee, M. Y., & Jeon, Y. J. (2015). Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 19(3), 211-8. https://doi.org/10.4196/kjpp.2015.19.3.211
Kim, Eun Jeong, et al. "Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 19,3 (2015): 211-8. doi: https://doi.org/10.4196/kjpp.2015.19.3.211
Kim EJ, Lee MY, Jeon YJ. Silymarin Inhibits Morphological Changes in LPS-Stimulated Macrophages by Blocking NF-κB Pathway. Korean J Physiol Pharmacol. 2015 May;19(3):211-8. doi: 10.4196/kjpp.2015.19.3.211. Epub 2015 Apr 30. PMID: 25954125; PMCID: PMC4422960.
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Re: "Protective Role of Silymarin and Deferoxamine against Iron Dextran-Induced Renal Iron Deposition in Male Rats," and "Co-Administration of Silymarin and Deferoxamine against Kidney, Liver and Heart Iron Deposition in Male Iron Overload Rat Model".

International journal of preventive medicine

Mazaheri S, Moaeidi BA, Nematbakhsh M.
PMID: 25013703
Int J Prev Med. 2014 Jun;5(6):800-1.

No abstract available.

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Mazaheri S, Moaeidi BA, Nematbakhsh M. Re: "Protective Role of Silymarin and Deferoxamine against Iron Dextran-Induced Renal Iron Deposition in Male Rats," and "Co-Administration of Silymarin and Deferoxamine against Kidney, Liver and Heart Iron Deposition in Male Iron Overload Rat Model". Int J Prev Med. 2014;5(6):800-1
Mazaheri, S., Moaeidi, B. A., & Nematbakhsh, M. (2014). Re: "Protective Role of Silymarin and Deferoxamine against Iron Dextran-Induced Renal Iron Deposition in Male Rats," and "Co-Administration of Silymarin and Deferoxamine against Kidney, Liver and Heart Iron Deposition in Male Iron Overload Rat Model". International journal of preventive medicine, 5(6), 800-1.
Mazaheri, Safoora, et al. "Re: "Protective Role of Silymarin and Deferoxamine against Iron Dextran-Induced Renal Iron Deposition in Male Rats," and "Co-Administration of Silymarin and Deferoxamine against Kidney, Liver and Heart Iron Deposition in Male Iron Overload Rat Model"." International journal of preventive medicine vol. 5,6 (2014): 800-1.
Mazaheri S, Moaeidi BA, Nematbakhsh M. Re: "Protective Role of Silymarin and Deferoxamine against Iron Dextran-Induced Renal Iron Deposition in Male Rats," and "Co-Administration of Silymarin and Deferoxamine against Kidney, Liver and Heart Iron Deposition in Male Iron Overload Rat Model". Int J Prev Med. 2014 Jun;5(6):800-1. PMID: 25013703; PMCID: PMC4085936.
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Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral mitochondria isolated from hypoxia-exposed rats in vitro.

Neural regeneration research

Yan W, Liu J.
PMID: 25558222
Neural Regen Res. 2012 Sep 25;7(27):2099-106. doi: 10.3969/j.issn.1673-5374.2012.27.003.

Mitochondrial dysfunction is the key pathogenic mechanism of cerebral injury induced by high-altitude hypoxia. Some Chinese herbal monomers may exert anti-hypoxic effects through enhancing the efficiency of oxidative phosphorylation. In this study, effects of 10 kinds of Chinese herbal...

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Yan W, Liu J. Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral mitochondria isolated from hypoxia-exposed rats in vitro. Neural Regen Res. 2012;7(27):2099-106doi: 10.3969/j.issn.1673-5374.2012.27.003.
Yan, W., & Liu, J. (2012). Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral mitochondria isolated from hypoxia-exposed rats in vitro. Neural regeneration research, 7(27), 2099-106. https://doi.org/10.3969/j.issn.1673-5374.2012.27.003
Yan, Weihua, and Liu, Junze. "Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral mitochondria isolated from hypoxia-exposed rats in vitro." Neural regeneration research vol. 7,27 (2012): 2099-106. doi: https://doi.org/10.3969/j.issn.1673-5374.2012.27.003
Yan W, Liu J. Effects of Chinese herbal monomers on oxidative phosphorylation and membrane potential in cerebral mitochondria isolated from hypoxia-exposed rats in vitro. Neural Regen Res. 2012 Sep 25;7(27):2099-106. doi: 10.3969/j.issn.1673-5374.2012.27.003. PMID: 25558222; PMCID: PMC4281410.
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Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant.

Journal of pharmacy & bioallied sciences

Parveen R, Baboota S, Ali J, Ahuja A, Ahmad S.
PMID: 26681893
J Pharm Bioallied Sci. 2015 Oct-Dec;7(4):321-4. doi: 10.4103/0975-7406.168037.

BACKGROUND: Silymarin, a flavonolignan from "milk thistle" (Silybum marianum) plant is used almost exclusively for hepatoprotection. Because of its low bioavailability, it was incorporated into a nanoemulsion formulation. The aim of the present study was to check the stability...

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Parveen R, Baboota S, Ali J, et al. Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant. J Pharm Bioallied Sci. 2015;7(4):321-4doi: 10.4103/0975-7406.168037.
Parveen, R., Baboota, S., Ali, J., Ahuja, A., & Ahmad, S. (2015). Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant. Journal of pharmacy & bioallied sciences, 7(4), 321-4. https://doi.org/10.4103/0975-7406.168037
Parveen, Rabea, et al. "Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant." Journal of pharmacy & bioallied sciences vol. 7,4 (2015): 321-4. doi: https://doi.org/10.4103/0975-7406.168037
Parveen R, Baboota S, Ali J, Ahuja A, Ahmad S. Stability studies of silymarin nanoemulsion containing Tween 80 as a surfactant. J Pharm Bioallied Sci. 2015 Oct-Dec;7(4):321-4. doi: 10.4103/0975-7406.168037. PMID: 26681893; PMCID: PMC4678981.
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Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats.

Veterinary world

Reddy MK, Reddy AG, Kumar BK, Madhuri D, Boobalan G, Reddy MA.
PMID: 28246450
Vet World. 2017 Jan;10(1):74-80. doi: 10.14202/vetworld.2017.74-80. Epub 2017 Jan 19.

AIM: The aim of this study is to evaluate the hepatoprotective effect of rutin (RTN) in comparison to silymarin (SLM) against acetaminophen (APAP)-induced hepatotoxicity in rats.MATERIALS AND METHODS: Male Wistar albino rats (n=24) of 3 months age were equally...

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Reddy MK, Reddy AG, Kumar BK, et al. Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats. Vet World. 2017;10(1):74-80doi: 10.14202/vetworld.2017.74-80.
Reddy, M. K., Reddy, A. G., Kumar, B. K., Madhuri, D., Boobalan, G., & Reddy, M. A. (2017). Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats. Veterinary world, 10(1), 74-80. https://doi.org/10.14202/vetworld.2017.74-80
Reddy, M Kasi, et al. "Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats." Veterinary world vol. 10,1 (2017): 74-80. doi: https://doi.org/10.14202/vetworld.2017.74-80
Reddy MK, Reddy AG, Kumar BK, Madhuri D, Boobalan G, Reddy MA. Protective effect of rutin in comparison to silymarin against induced hepatotoxicity in rats. Vet World. 2017 Jan;10(1):74-80. doi: 10.14202/vetworld.2017.74-80. Epub 2017 Jan 19. PMID: 28246450; PMCID: PMC5301182.
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Effects of gamma rays on rat testis tissue according to the morphological parameters and immunohistochemistry: radioprotective role of silymarin.

Electronic physician

Marzban M, Anjamshoa M, Jafari P, Masoumi H, Ahadi R, Fatehi D.
PMID: 28848626
Electron Physician. 2017 Jun 25;9(6):4524-4532. doi: 10.19082/4524. eCollection 2017 Jun.

OBJECTIVE: To determine the radioprotective effects of Silymarin in adult male Sprague-Dawley rats irradiated with γ-rays.METHODS: The present experimental study was performed in Tehran University of Medical Sciences, Tehran, Iran from December 2009 to March 2010. The study was...

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Marzban M, Anjamshoa M, Jafari P, et al. Effects of gamma rays on rat testis tissue according to the morphological parameters and immunohistochemistry: radioprotective role of silymarin. Electron Physician. 2017;9(6):4524-4532doi: 10.19082/4524.
Marzban, M., Anjamshoa, M., Jafari, P., Masoumi, H., Ahadi, R., & Fatehi, D. (2017). Effects of gamma rays on rat testis tissue according to the morphological parameters and immunohistochemistry: radioprotective role of silymarin. Electronic physician, 9(6), 4524-4532. https://doi.org/10.19082/4524
Marzban, Mohsen, et al. "Effects of gamma rays on rat testis tissue according to the morphological parameters and immunohistochemistry: radioprotective role of silymarin." Electronic physician vol. 9,6 (2017): 4524-4532. doi: https://doi.org/10.19082/4524
Marzban M, Anjamshoa M, Jafari P, Masoumi H, Ahadi R, Fatehi D. Effects of gamma rays on rat testis tissue according to the morphological parameters and immunohistochemistry: radioprotective role of silymarin. Electron Physician. 2017 Jun 25;9(6):4524-4532. doi: 10.19082/4524. eCollection 2017 Jun. PMID: 28848626; PMCID: PMC5557131.
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Showing 1 to 12 of 512 entries