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Association between antipsychotic/antidepressant drug treatments and hospital admissions in schizophrenia assessed using a mental health case register.

NPJ schizophrenia

Cardinal RN, Savulich G, Mann LM, Fernández-Egea E.
PMID: 27336041
NPJ Schizophr. 2015 Oct 21;1:15035. doi: 10.1038/npjschz.2015.35. eCollection 2015.

BACKGROUND: The impact of psychotropic drug choice upon admissions for schizophrenia is not well understood.AIMS: To examine the association between antipsychotic/antidepressant use and time in hospital for patients with schizophrenia.METHODS: We conducted an observational study, using 8 years' admission...

The Charles Bonnet syndrome: symptomatic relief with atypical neuroleptics: a case series.

International journal of psychiatry in clinical practice

Barnes JJ.
PMID: 24931789
Int J Psychiatry Clin Pract. 2001;5(2):141-4. doi: 10.1080/136515001300374894.

We describe a consecutive case series of five patients who all fulfil published criteria for Charles Bonnet syndrome. Four of the five patients showed a good response to the atypical antipsychotic sulpiride. The nature of the Charles Bonnet syndrome...

Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

Citó MC, Silva MI, Santos LK, Fernandes ML, Melo FH, Aguiar JA, Lopes IS, Sousa PB, Vasconcelos SM, Macêdo DS, Sousa FC.
PMID: 25493384
Braz J Med Biol Res. 2015 Jan;48(1):57-64. doi: 10.1590/1414-431x20144215. Epub 2014 Nov 07.

Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the...

Effects of Sulpiride on True and False Memories of Thematically Related Pictures and Associated Words in Healthy Volunteers.

Frontiers in psychiatry

Guarnieri RV, Ribeiro RL, de Souza AA, Galduróz JC, Covolan L, Bueno OF.
PMID: 27047394
Front Psychiatry. 2016 Mar 18;7:28. doi: 10.3389/fpsyt.2016.00028. eCollection 2016.

Episodic memory, working memory, emotional memory, and attention are subject to dopaminergic modulation. However, the potential role of dopamine on the generation of false memories is unknown. This study defined the role of the dopamine D2 receptor on true...

Dual activation by lisuride of central serotonin 5-HT(1A) and dopamine D(2) receptor sites: drug discrimination and receptor binding studies.

Behavioural pharmacology

Kimura K, Akai T, Nakamura K, Yamaguchi M, Nakagawa H, Oshino N.
PMID: 11224054
Behav Pharmacol. 1991 Apr;2(2):105-112.

To investigate central serotonergic (5-HT) and dopaminergic (DA) actions of lisuride, the discriminative properties of lisuride (0.05mg/kg, i.p.) in rats were investigated, in addition to the radioligand binding of the compound to 5-HT and DA receptor subtypes. Lisuride was...

The role of monoamine uptake in the discriminative stimulus effects of cocaine and related compounds.

Behavioural pharmacology

Baker LE, Riddle EE, Saunders RB, Appel JB.
PMID: 11224173
Behav Pharmacol. 1993 Feb;4(1):69-79.

The involvement of monoamine neurotransmitter uptake in the discriminative stimulus effects of cocaine was examined in rats (n = 48) trained to discriminate 10mg/kg of this substance from saline in a two-level, water-reinforced (FR 20), drug discrimination situation. Compounds...

Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study.

Behavioural pharmacology

Muscat R, Patel J, Trout SJ, Wieczorek W, Kruk ZL.
PMID: 11224210
Behav Pharmacol. 1993;4(4):411-418.

Behavioural sensitization to the locomotor stimulant effect of (+)-amphetamine or quinpirole was induced in rats by intermittent drug administration. Once established, endogenous dopamine release (DA) was measured in slices containing nucleus accumbens using fast cyclic voltammetry. DA release induced...

Role of Dopaminergic D2 Receptors in the Regulation of Glutamic Acid Decarboxylase Messenger RNA in the Striatum of the Rat.

The European journal of neuroscience

Caboche J, Vernier P, Rogard M, Julien JF, Mallet J, Besson MJ.
PMID: 12106353
Eur J Neurosci. 1992;4(5):438-447. doi: 10.1111/j.1460-9568.1992.tb00894.x.

Levels of messenger RNA (mRNA) encoding glutamic acid decarboxylase (GAD) and preproenkephalin (PPE) were measured by Northern blot and in situ hybridization analyses in the striatum of the rat, after chronic injections of two neuroleptics, sulpiride and haloperidol. The...

Comparison of the effect of levodopa and bromocriptine on naloxone-precipitated morphine withdrawal symptoms in mice.

Human psychopharmacology

Samini M, Fakhrian R, Mohagheghi M, Dehpour AR.
PMID: 12404338
Hum Psychopharmacol. 2000 Mar;15(2):95-101. doi: 10.1002/(SICI)1099-1077(200003)15:2<95::AID-HUP148>3.0.CO;2-A.

In this study, the effect of l-dopa and bromocriptine on morphine withdrawal syndrome was compared. Both l-dopa (125, 250 mg/kg, i.p.) and low doses of bromocriptine (0.04, 0.08 mg/kg, i.p.) potentiated naloxone-induced morphine withdrawal symptoms such as jumping, climbing...

Discriminative stimulus effects of the optical isomers of 3,4-methylenedioxyamphetamine (MDA).

Behavioural pharmacology

Broadbent J, Appel JB, Michael EK, Ricker JH.
PMID: 11224147
Behav Pharmacol. 1992 Oct;3(5):443-454.

The isomers of 3,4-methylenedioxyamphetamine (MDA) functioned as discriminative stimuli in rats trained to discriminate either (-) MDA (1.25mg/kg) or (+) MDA (1.25mg/kg) from saline. Dose- and time-response curves indicated that drug lever selection occurred at doses of at least...

Enantioselective high-performance liquid chromatographic method for the determination of baclofen in human plasma.

Talanta

Hefnawy MM, Aboul-Enein HY.
PMID: 18969231
Talanta. 2003 Dec 04;61(5):667-73. doi: 10.1016/S0039-9140(03)00352-7.

A new analytical method for the separation and determination of R-(-)- and S-(+)- baclofen enantiomers in human plasma by high-performance liquid chromatography (HPLC) with UV detection was developed. Enantioselective resolution of the baclofen enantiomers was achieved by using teicoplanin...

Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain.

Archives of gerontology and geriatrics

Asanuma M, Ogawa N, Haba K, Hirata H, Mori A.
PMID: 15374420
Arch Gerontol Geriatr. 1991 Nov-Dec;13(3):271-8. doi: 10.1016/0167-4943(91)90049-v.

The calcium (Ca) antagonist flunarizine hydrochloride (FNZ) has been reported to induce parkinsonism, especially in the elderly. The effects of FNZ on dopamine receptors in rat striatal membranes, especially in aged rats, were studied using radiolabeled receptor assay. Similar...

Showing 1 to 12 of 170 entries