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Showing 1 to 12 of 30 entries
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Add-on histamine receptor-3 antagonist for allergic rhinitis: a double blind randomized crossover trial using the environmental exposure unit.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

North ML, Walker TJ, Steacy LM, Hobsbawn BG, Allan RJ, Hackman F, Sun X, Day AG, Ellis AK.
PMID: 25024716
Allergy Asthma Clin Immunol. 2014 Jul 03;10(1):33. doi: 10.1186/1710-1492-10-33. eCollection 2014.

BACKGROUND: Oral antihistamines that target the histamine receptor-1, such as fexofenadine, offer suboptimal relief of allergic rhinitis-associated nasal congestion. Combinations with oral sympathomimetics, such as pseudoephedrine, relieve congestion but produce side effects. Previous animal and human studies with histamine...

Early Extracorporeal Membrane Oxygenation Support for 5-Fluorouracil-induced Acute Heart Failure with Cardiogenic Shock.

Heart views : the official journal of the Gulf Heart Association

Höllriegel R, Fischer J, Schuler G.
PMID: 24949186
Heart Views. 2014 Jan;15(1):26-8. doi: 10.4103/1995-705X.132144.

A 50-year-old man with no previous history of cardiovascular disease or risk factors was admitted for syncope and orthopnea. Importantly, he underwent recent chemotherapy with 5-fluorouracil (5-FU) until 1 day before his acute presentation. In the emergency room, patient...

Motion sickness: an overview.

Drugs in context

Leung AK, Hon KL.
PMID: 32158479
Drugs Context. 2019 Dec 13;8. doi: 10.7573/dic.2019-9-4. eCollection 2019.

BACKGROUND: Motion sickness is a common phenomenon that affects almost everybody at some point in their lifetime. Clinicians should be familiar with the proper management of this condition.OBJECTIVE: To provide an update on the current understanding of the pathophysiology...

Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice.

Journal of cachexia, sarcopenia and muscle

Rodrigues ACZ, Messi ML, Wang ZM, Bonilla HJ, Freeman WM, Delbono O.
PMID: 34546662
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1908-1924. doi: 10.1002/jcsm.12790. Epub 2021 Sep 21.

BACKGROUND: The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has serious side effects...

Severe maculopapular eruption due to pseudoephedrine in a combination drug, with cross-reactivity to phenylephrine.

Contact dermatitis

Gratacós Gómez AR, González Jimenez OM, Palacios Cañas A, Moreno Lozano L, Juan Cencerrado M, Gómez Torrijos E.
PMID: 34313328
Contact Dermatitis. 2021 Dec;85(6):716-717. doi: 10.1111/cod.13951. Epub 2021 Aug 09.

No abstract available.

Acute Stress Cardiomyopathy: Heart of pheochromocytoma.

Annales d'endocrinologie

Cornu E, Motiejunaite J, Belmihoub I, Vidal-Petiot E, Mirabel M, Amar L.
PMID: 32988608
Ann Endocrinol (Paris). 2021 Jun;82(3):201-205. doi: 10.1016/j.ando.2020.03.011. Epub 2020 Mar 18.

Stress cardiomyopathy (SCM) is a syndrome characterized by transient regional systolic dysfunction of the left ventricle in the absence of angiographic evidence of coronaropathy. This abnormality is associated with high levels of catecholamines. Stress cardiomyopathy is also called Takotsubo...

Pediatrician's cough and cold medication prescription for hypothetical cases - A cross-sectional multi-centric study.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Chandelia S, Dhankar M, Salhan M.
PMID: 27013910
Saudi Pharm J. 2016 Mar;24(2):176-81. doi: 10.1016/j.jsps.2015.02.011. Epub 2015 Mar 19.

BACKGROUND: Concerns over inappropriate use of cough and cold medication (CCM) in children have been raised. In addition to being ineffective, these are now considered toxic for young children. Despite this fact studies from some regions have shown high...

Bronchial asthma: diagnosis and long-term treatment in adults.

Deutsches Arzteblatt international

Ukena D, Fishman L, Niebling WB.
PMID: 19626179
Dtsch Arztebl Int. 2008 May;105(21):385-94. doi: 10.3238/arztebl.2008.0385. Epub 2008 May 23.

INTRODUCTION: Bronchial asthma is a serious global health problem. 5% to 10% of persons of all ages suffer from this chronic airway disorder. This review article presents important considerations of diagnosis and treatment in view of the current national...

QSPR analysis of some agonists and antagonists of α-adrenergic receptors.

Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents

Kawczak P, Bober L, Bączek T.
PMID: 25589825
Med Chem Res. 2015;24:372-382. doi: 10.1007/s00044-014-1130-x. Epub 2014 Jul 15.

Thirty-three compounds belonging to the sympatholytics and sympathomimetics were analyzed during the study. The biological activity data for the parameters of binding affinity to the α

Long-term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice.

Journal of cachexia, sarcopenia and muscle

Rodrigues ACZ, Messi ML, Wang ZM, Bonilla HJ, Freeman WM, Delbono O.
PMID: 34546662
J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):1908-1924. doi: 10.1002/jcsm.12790. Epub 2021 Sep 21.

BACKGROUND: The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has serious side effects...

Acetazolamide increases locomotion, exploratory behavior, and weight loss following social stress: .

Metabolism open

Woodman R, Student J, Malcolm T, Miller C, Lockette W.
PMID: 32812910
Metabol Open. 2020 Jan 13;5:100023. doi: 10.1016/j.metop.2020.100023. eCollection 2020 Mar.

Sympathomimetics are effective, centrally acting drugs that induce weight loss through their potent anorexic and locomotor properties. We reported that sympathomimetics antagonize catecholamine-dependent, alpha-2 adrenergic receptor-dependent signal transduction mediated by chloride/bicarbonate transport. We posit that other drugs that target...

Sex Differences in Substance Use and Misuse: A Toxicology Investigators' Consortium (ToxIC) Registry Analysis.

Substance abuse and rehabilitation

Beauchamp GA, Carey JL, Hurwitz MB, Tully BN, Cook MD, Cannon RD, Katz KD, Koons AL, Kincaid H, Greenberg MR.
PMID: 33061740
Subst Abuse Rehabil. 2020 Sep 29;11:23-31. doi: 10.2147/SAR.S263165. eCollection 2020.

BACKGROUND: Variations between male and female populations are previously reported in classes of harmfully used/misused drugs, severity of substance use disorder and risk of relapse. The aim of this study was to provide a review of bedside medical toxicologist...

Showing 1 to 12 of 30 entries