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Showing 1 to 12 of 347 entries
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Ultrasound-triggered local anaesthesia.

Nature biomedical engineering

Rwei AY, Paris JL, Wang B, Wang W, Axon CD, Vallet-Regí M, Langer R, Kohane DS.
PMID: 29152410
Nat Biomed Eng. 2017;1:644-653. doi: 10.1038/s41551-017-0117-6. Epub 2017 Aug 09.

On-demand relief of local pain would allow patients to control the timing, intensity and duration of nerve block in a safe and non-invasive manner. Ultrasound would be a suitable trigger for such a system, as it is in common...

Acute cocaine exposure elicits rises in calcium in arousal-related laterodorsal tegmental neurons.

Pharmacology research & perspectives

Lambert MØ, Ipsen TH, Kohlmeier KA.
PMID: 28596834
Pharmacol Res Perspect. 2016 Dec 23;5(1):e00282. doi: 10.1002/prp2.282. eCollection 2017 Feb.

Cocaine has strong reinforcing properties, which underlie its high addiction potential. Reinforcement of use of addictive drugs is associated with rises in dopamine (DA) in mesoaccumbal circuitry. Excitatory afferent input to mesoaccumbal circuitry sources from the laterodorsal tegmental nucleus...

Neurophysiological mechanisms of bradykinin-evoked mucosal chloride secretion in guinea pig small intestine.

World journal of gastrointestinal pathophysiology

Qu MH, Ji WS, Zhao TK, Fang CY, Mao SM, Gao ZQ.
PMID: 26909238
World J Gastrointest Pathophysiol. 2016 Feb 15;7(1):150-9. doi: 10.4291/wjgp.v7.i1.150.

AIM: To investigate the mechanism for bradykinin (BK) to stimulate intestinal secretomotor neurons and intestinal chloride secretion.METHODS: Muscle-stripped guinea pig ileal preparations were mounted in Ussing flux chambers for the recording of short-circuit current (Isc). Basal Isc and Isc...

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats.

Iranian journal of medical sciences

Yuan C, Zhang Y, Zhang Y, Cao S, Wang Y, Fu B, Yu T.
PMID: 27365548
Iran J Med Sci. 2016 Jul;41(4):275-82.

BACKGROUND: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown. We aimed to elucidate the effects of different concentrations of ketamine...

Transient Sensitivity of Rat Cerebellar Purkinje Cells to N-methyl-D-aspartate during Development. A Voltage Clamp Study in in vitro Slices.

The European journal of neuroscience

Krupa M, Crepel F.
PMID: 12106038
Eur J Neurosci. 1990;2(4):312-316. doi: 10.1111/j.1460-9568.1990.tb00423.x.

In vitro sagittal slices of immature rat cerebellum were used to study the development of the sensitivity of Purkinje cells (PC) to L-glutamate (Glu) and N-methyl-D-aspartate (NMDA). In 8-day-old animals, all PCs recorded in magnesium-free medium responded to iontophoretic...

Sites of [3H]taurine Uptake in the Rat Substantia Nigra in Relation to the Release of Taurine from the Striatonigral Pathway.

The European journal of neuroscience

Della Corte L, Bolam JP, Clarke DJ, Parry DM, Smith AD.
PMID: 12106102
Eur J Neurosci. 1990 Jan;2(1):50-61. doi: 10.1111/j.1460-9568.1990.tb00380.x.

The autoradiographic localization of radiolabelled taurine taken up in the rat substantia nigra in vivo together with conditions of release of the [3H]taurine taken up into brain slices were studied to determine whether they are consistent with the hypothesis...

Development of Neurons and Glial Cells in Cerebral Cortex, Cultured in the Presence or Absence of Bioelectric Activity: Morphological Observations.

The European journal of neuroscience

Ramakers GJ, Raadsheer FC, Corner MA, Ramaekers FC, Van Leeuwen FW.
PMID: 12106212
Eur J Neurosci. 1991;3(2):140-153. doi: 10.1111/j.1460-9568.1991.tb00074.x.

Chronic blockade of bioelectric activity (BEA) has been shown to increase neuronal cell death in tissue culture, but the effects of this treatment on non-neuronal cells have not been investigated. To determine which cell types are affected by chronic...

Climbing Fibres as a Source of Nitric Oxide in the Cerebellum.

The European journal of neuroscience

Southam E, Garthwaite J.
PMID: 12106196
Eur J Neurosci. 1991;3(4):379-382. doi: 10.1111/j.1460-9568.1991.tb00825.x.

Exposure of adult rat cerebellar slices to a moderately raised K+ concentration (15 mM) caused a large (30-fold) rise in the levels of cyclic GMP. Excitatory amino acid antagonists failed to inhibit this response, nor could it be mimicked...

Inhibition of the Sodium Channel by SK&F 96365, an Inhibitor of the Receptor-Operated Calcium Channel, in Mouse Diaphragm.

Journal of biomedical science

Hong SJ, Lin WW, Chang CC.
PMID: 11725023
J Biomed Sci. 1994 Jun;1(3):172-178. doi: 10.1007/BF02253347.

The effects of SK&F 96365, a blocker of the receptor-operated Ca(2+) channel, on contractilities and the Na(+) channel of mouse diaphragm were studied. SK&F 96365 (10-50 &mgr;M) reversibly inhibited twitches, tetanic contractions and muscle and nerve action potentials. The...

Astrocyte activation of presynaptic metabotropic glutamate receptors modulates hippocampal inhibitory synaptic transmission.

Neuron glia biology

Liu QS, Xu Q, Kang J, Nedergaard M.
PMID: 16755304
Neuron Glia Biol. 2004 Nov;1(4):307-16. doi: 10.1017/S1740925X05000190.

In the CNS, fine processes of astrocytes often wrap around dendrites, axons and synapses, which provides an interface where neurons and astrocytes might interact. We have reported previously that selective Ca(2+) elevation in astrocytes, by photolysis of caged Ca(2+)...

Rapid Correlation between the Leaves of Spinach and the Photocontrol of a Peroxidase Activity.

Plant physiology

Karege F, Penel C, Greppin H.
PMID: 16662225
Plant Physiol. 1982 Feb;69(2):437-41. doi: 10.1104/pp.69.2.437.

The activity of a basic peroxidase extracted at high pH from spinach (Spinacia oleracea) leaves is modified by an irradiation with 2-minute red light or 2-minute far red light. This fast response, apparently mediated by phytochrome, is also detected...

Tetrodotoxin: comments on effects on squid axons.

Science (New York, N.Y.)

Moore JW, Narahashi T, Anderson NC, Blaustein MP, Watanabe A, Tasaki I, Singer I, Lerman L.
PMID: 17806275
Science. 1967 Jul 14;157(3785):220-1. doi: 10.1126/science.157.3785.220-a.

No abstract available.

Showing 1 to 12 of 347 entries