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Showing 1 to 12 of 1123 entries
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Age-related differences in fibrinolytic parameters in patients with acute traumatic brain injury.

Surgical neurology international

Nakae R, Yokobori S, Takayama Y, Kuwamoto K, Naoe Y, Yokota H.
PMID: 28966820
Surg Neurol Int. 2017 Sep 06;8:214. doi: 10.4103/sni.sni_56_17. eCollection 2017.

BACKGROUND: Coagulopathy and old age have been associated with poor outcomes in traumatic brain injury (TBI) patients; however, the relationships of coagulopathy and age with the acute phase of TBI remain unclear. We hypothesized that coagulation/fibrinolytic abnormalities are more...

Evaluation of clotting factor activities early after severe multiple trauma and their correlation with coagulation tests and clinical data.

World journal of emergency surgery : WJES

Burggraf M, Payas A, Kauther MD, Schoeneberg C, Lendemans S.
PMID: 26396589
World J Emerg Surg. 2015 Sep 22;10:43. doi: 10.1186/s13017-015-0038-1. eCollection 2015.

INTRODUCTION: Traumatic injuries are amongst the leading causes of death worldwide, frequently as a result of uncontrolled hemorrhage. Critical deficiencies in clotting factors have been noted in trauma-induced coagulopathy. However, the exact underlying conditions that result in devastating coagulopathies...

Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants.

Iranian biomedical journal

Alikhani Pour M, Sardari S, Eslamifar A, Azhar A, Rezvani M, Nazari M.
PMID: 28454485
Iran Biomed J. 2017 Nov;21(6):400-5. doi: 10.18869/acadpub.ibj.21.6.400. Epub 2017 Apr 29.

BACKGROUNG: Medicinal plants, as a complementary medicine, have been used to treat various diseases since ancient times. These plants have numerous beneficial applications and are the source of certain conventional drugs. In diseases such as stroke and ischemia, which...

Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?.

Journal of blood medicine

Korte W.
PMID: 25031548
J Blood Med. 2014 Jul 09;5:107-13. doi: 10.2147/JBM.S35395. eCollection 2014.

Circulating factor XIII (FXIII) consists of two active (A) and two carrier (B) subunits in tetrameric form. Congenital FXIII deficiency is a rare autosomal-recessive trait that mostly results from an FXIII A-subunit deficiency. Classic coagulation assays, such as prothrombin...

Study of Basic Coagulation Parameters among HIV Patients in Correlation to CD4 Counts and ART Status.

Journal of clinical and diagnostic research : JCDR

Thulasi Raman R, Manimaran D, Rachakatla P, Bharathi K, Afroz T, Sagar R.
PMID: 27437222
J Clin Diagn Res. 2016 May;10(5):EC04-6. doi: 10.7860/JCDR/2016/17459.7718. Epub 2016 May 01.

INTRODUCTION: HIV infection is known to cause coagulation abnormalities by various mechanism, especially during its late course.AIM: The objective of this study was to analyse platelet count, prothrombin time and activated partial thromboplastin time among HIV infected patients and...

The Results of Proximal Femoral Nail for Intertrochanteric Fracture in Hemodialysis Patient.

Hip & pelvis

Song KS, Yoon SP, Lee SK, Lee SH, Yang BS, Park BM, Yang IH, Lee BS, Yeom JU.
PMID: 28316963
Hip Pelvis. 2017 Mar;29(1):54-61. doi: 10.5371/hp.2017.29.1.54. Epub 2017 Mar 06.

PURPOSE: Hip fractures in hemodialysis patients are accompanied by high rates of complications and morbidities. Previous studies have mainly reported on nonunion and avascular necrosis of femoral neck fractures in this patient group. In this study the complication and...

Pathologic rupture of the spleen in a patient with acute myelogenous leukemia and leukostasis.

Revista brasileira de hematologia e hemoterapia

De Santis GC, Oliveira LC, Ramos AF, da Silva ND, Falcão RP.
PMID: 25031169
Rev Bras Hematol Hemoter. 2014 Jul-Aug;36(4):290-2. doi: 10.1016/j.bjhh.2014.05.006. Epub 2014 May 28.

Rupture of the spleen can be classified as spontaneous, traumatic, or pathologic. Pathologic rupture has been reported in infectious diseases such as infectious mononucleosis, and hematologic malignancies such as acute and chronic leukemias. Splenomegaly is considered the most relevant...

Acquired factor VIII deficiency: two case reports and a review of literature.

Experimental hematology & oncology

Mo L, Bao GC.
PMID: 28352491
Exp Hematol Oncol. 2017 Mar 24;6:8. doi: 10.1186/s40164-017-0068-3. eCollection 2017.

BACKGROUND: Acquired factor VIII (FVIII) deficiency, or acquired hemophilia A (AHA), is a rare autoimmune disorder involving antibody-mediated depletion of coagulation FVIII, leading to severe, life-threatening bleeding. The condition is often associated with other autoimmune disorders, and its treatment...

Thrombin generation measured as thrombin-antithrombin complexes predicts clinical outcomes in patients with cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Kalambokis GN, Oikonomou A, Baltayiannis G, Christou L, Kolaitis NI, Tsianos EV.
PMID: 25847196
Hepatol Res. 2016 Mar;46(3):E36-44. doi: 10.1111/hepr.12520. Epub 2015 May 22.

AIM: Hypercoagulability has been detected in patients with cirrhosis yet its clinical significance remains unclear. We investigated the association of hypercoagulability with clinical outcomes in patients with cirrhosis.METHODS: Thrombin-antithrombin (TAT) complexes as thrombin generation (TG) marker, D-dimer, antithrombin (AT),...

Prevalence and Resolution of Lupus Anticoagulant in Children.

The Ochsner journal

Kallanagowdar C, Chauhan A, Puertolas MV, Warrier R.
PMID: 27303229
Ochsner J. 2016;16(2):172-5.

BACKGROUND: Lupus anticoagulant (LA) is an autoantibody that inhibits phospholipid-dependent reactions. Studies on the incidence and prevalence of LA in the pediatric population are lacking. The objective of our study was to determine the incidence and potential risk of...

Lupus anticoagulant and anticardiolipin antibodies in SLE with secondary Antiphospholipid Antibody Syndrome.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Garg S, Kurien A.
PMID: 27263620
Turk J Haematol. 2007 Jun 05;24(2):69-74.

Thirty patients with systemic lupus erythematosus (SLE) and suspected secondary antiphospholipid antibody syndrome (APLAS) were evaluated in the study based on their clinical manifestations. The aim was to study the prevalence of various antiphospholipid antibodies, compare the tests used...

Plasma levels of thrombin activatable fibrinolysis inhibitor antigen in active and inactive inflammatory bowel disease.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Özcan MA, Akarsu M, Demirkan F, Akpınar H, Yüksel F, Özsan GH, Ündar B, Pişkin Ö, Alacacıoğlu İ.
PMID: 27265290
Turk J Haematol. 2006 Jun 05;23(2):94-9.

BACKGROUND: The clinical course of patients with inflammatory bowel disease (IBD) is frequently complicated by thromboembolic events and may involve the arterial and venous systems. Although not uniformly documented, several studies document substantial alterations in markers of coagulation and...

Showing 1 to 12 of 1123 entries