Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 38 entries
Sorted by: Best Match Show Resources per page
Iodine Supplementation throughout Pregnancy Does Not Prevent the Drop in FT4 in the Second and Third Trimesters in Women with Normal Initial Thyroid Function.

European thyroid journal

Brucker-Davis F, Panaïa-Ferrari P, Gal J, Fénichel P, Hiéronimus S.
PMID: 24847452
Eur Thyroid J. 2013 Sep;2(3):187-94. doi: 10.1159/000350882. Epub 2013 Jul 16.

OBJECTIVES: The aim of the study was to determine the evolution of thyroid tests throughout pregnancy and postpartum in healthy women with and without iodine supplementation.METHODS: This was a prospective, randomized, interventional study of iodine supplementation (150 μg/day) from...

Total and free triiodothyronine in human serum.

The Journal of clinical investigation

Nauman JA, Nauman A, Werner SC.
PMID: 16695923
J Clin Invest. 1967 Aug;46(8):1346-55. doi: 10.1172/JCI105627.

A reliable method has been developed for the determination of total serum T3, dialyzable fraction (DFT3), and absolute concentration of free T3 (AFT3). Total T3 values (mean +/- SD) were: healthy euthyroid subjects, 0.33 +/- 0.07 mug per 100...

Molecular basis of inherited thyroxine-binding globulin defects.

Trends in endocrinology and metabolism: TEM

Janssen OE, Bertenshaw R, Takeda K, Weiss R, Refetoff S.
PMID: 18407078
Trends Endocrinol Metab. 1992 Mar;3(2):49-53. doi: 10.1016/1043-2760(92)90043-z.

Thyroxine-binding globulin (TBG) is a liver glycoprotein that transports thyroid hormones in serum. Inherited TBG defects appear as partial or complete deficiency and TBG excess. Sequencing of the TBG gene located on the X-chromosome has revealed nucleotide substitutions in...

A NOVEL MUTATION CAUSING COMPLETE THYROID BINDING GLOBULIN DEFICIENCY (TBG-CD MIA) IN A MALE WITH COEXISTING GRAVES DISEASE.

AACE clinical case reports

Berger HR, Creech MK, Hannoush Z, Watanabe Y, Kargi A, Weiss RE.
PMID: 28553659
AACE Clin Case Rep. 2017;3(2):e134-e139. doi: 10.4158/EP161421.CR.

OBJECTIVE: An asymptomatic male was found on screening to have a low serum TSH and total TMETHODS: The laboratory testing included total TRESULTS: A 35-year-old East Indian male was referred to endocrinology because of abnormal thyroid function tests (TFTs):...

Severe hypothyroidism associated with the degree of edema in a patient with nephrosis.

Clinics and practice

Kinoshita H, Ishii A, Hayakawa A, Yasuda M, Inoshita S, Yakushiji F.
PMID: 24765339
Clin Pract. 2011 Oct 13;1(3):e78. doi: 10.4081/cp.2011.e78. eCollection 2011 Jul 01.

We report the pleural fluid values of thyroid hormones and their carrier proteins in a patient who suffered from nephrotic syndrome with renal insufficiency and transient hypothyroidism. The pleural effusion was transudate. The concentrations of thyroxine-binding globulin (TBG), thyroxine-binding...

Effect of Albumin Polymorphism on Thyroid Hormones: A Case Report and Literature Review.

Cureus

Mahendhar R, Shahbaz A, Riaz M, Aninyei M, Reich DM, Sachmechi I.
PMID: 30197844
Cureus. 2018 Jul 01;10(7):e2903. doi: 10.7759/cureus.2903.

Familial dysalbuminemic hyperthyroxinemia (FDH) is the most common cause of the inherited increase of serum thyroxine in Caucasians. This disorder occurs due to a missense mutation in the human serum albumin, resulting in an increased affinity of thyroxine to...

Promoter CAG is more efficient than hepatocyte‑targeting TBG for transgene expression via rAAV8 in liver tissues.

Molecular medicine reports

Kang J, Huang L, Zheng W, Luo J, Zhang X, Song Y, Liu A.
PMID: 34779500
Mol Med Rep. 2022 Jan;25(1). doi: 10.3892/mmr.2021.12532. Epub 2021 Nov 15.

The recombinant adeno‑associated virus 8 (rAAV8) vector is a widely used tool in basic research and clinical trials. The cytomegalovirus immediate‑early enhancer/chicken β‑actin (CAG) promoter is a synthetic promoter used in adenoviral constructs with a wide spectrum and notable...

Familial dysalbuminemic hyperthyroxinemia confounding management of coexistent autoimmune thyroid disease.

Endocrinology, diabetes & metabolism case reports

Khoo S, Lyons G, Solomon A, Oddy S, Halsall D, Chatterjee K, Moran C.
PMID: 32101523
Endocrinol Diabetes Metab Case Rep. 2020 Feb 26;2020. doi: 10.1530/EDM-19-0161. Epub 2020 Feb 26.

SUMMARY: Familial dysalbuminemic hyperthyroxinemia (FDH) is a cause of discordant thyroid function tests (TFTs), due to interference in free T4 assays, caused by the mutant albumin. The coexistence of thyroid disease and FDH can further complicate diagnosis and potentially...

Histone variant macroH2A1 deletion in mice causes female-specific steatosis.

Epigenetics & chromatin

Boulard M, Storck S, Cong R, Pinto R, Delage H, Bouvet P.
PMID: 20359320
Epigenetics Chromatin. 2010 Apr 01;3(1):8. doi: 10.1186/1756-8935-3-8.

BACKGROUND: Vertebrate heterochromatin contains a non-allelic variant of the histone H2A called macroH2A1, which has the characteristic of being three times the size of the canonical H2A. The macroH2A1 C-terminal extension can recruit onto chromatin the poly-ADP-ribose polymerase (PARP)1,...

Improving the Dutch Newborn Screening for Central Congenital Hypothyroidism by Using 95% Reference Intervals for Thyroxine-Binding Globulin.

European thyroid journal

Stroek K, Heijboer AC, van Veen-Sijne M, Bosch AM, van der Ploeg CPB, Zwaveling-Soonawala N, de Jonge R, van Trotsenburg ASP, Boelen A.
PMID: 34178708
Eur Thyroid J. 2021 Jun;10(3):222-229. doi: 10.1159/000513516. Epub 2021 Mar 05.

INTRODUCTION: Newborn screening (NBS) for congenital hypothyroidism (CH) in the Netherlands consists of thyroxine (T4), thyroid-stimulating hormone (TSH), and T4-binding globulin (TBG) measurements to detect thyroidal CH and central CH (CH-C). CH-C is detected by T4 or a calculated...

Qualitative and semiquantitative assessment of thyroid hormone binding proteins in greyhounds and other dog breeds.

Domestic animal endocrinology

Shiel RE, Nolan CM, Nally JE, Refsal KR, Mooney CT.
PMID: 33774426
Domest Anim Endocrinol. 2021 Jul;76:106623. doi: 10.1016/j.domaniend.2021.106623. Epub 2021 Feb 23.

Total thyroxine (T4) concentrations are lower in healthy greyhounds compared to most other non-sighthound breeds. In humans, variations in the structure or concentration of the major thyroid hormone binding proteins are responsible for most reported differences between total T4...

The effect of specific binding proteins on immunoassay measurements of total and free thyroid hormones and cortisol.

Therapeutic advances in endocrinology and metabolism

Gant Kanegusuku A, Araque KA, Nguyen H, Wei B, Hosseini S, Soldin SJ.
PMID: 33552466
Ther Adv Endocrinol Metab. 2021 Jan 27;12:2042018821989240. doi: 10.1177/2042018821989240. eCollection 2021.

BACKGROUND: Immunoassay (IA) measurements of thyroid hormones have previously given inaccurate results of triiodothyronine (T3), free triiodothyronine (FT3), and free thyroxine (FT4) when concentrations of TBG are low. We evaluate the hypothesis that abnormal concentrations of specific binding proteins...

Showing 1 to 12 of 38 entries