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Showing 1 to 12 of 348 entries
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Evaluation of TLR2 and 4 in Chronic Periodontitis.

Journal of clinical and diagnostic research : JCDR

Ilango P, Mahalingam A, Parthasarathy H, Katamreddy V, Subbareddy V.
PMID: 27504418
J Clin Diagn Res. 2016 Jun;10(6):ZC86-9. doi: 10.7860/JCDR/2016/18353.8027. Epub 2016 Jun 01.

INTRODUCTION: Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection due to oral bacteria. Members of Toll-Like Receptor (TLR) family recognize conserved microbial structures, such as bacterial...

The effect of interleukin 17 and Toll-like receptor 2 on CD11b expression and apoptosis of neutrophils in zymosaninduced arthritis and paw oedema.

Central-European journal of immunology

Milanova V, Ivanovska N, Dimitrova P.
PMID: 26155114
Cent Eur J Immunol. 2014;39(2):131-41. doi: 10.5114/ceji.2014.43712. Epub 2014 Jun 27.

We investigated the effect of interleukin (IL)-17 on Ly6G(+) cell apoptosis in zymosan-induced arthritis (ZIA) and oedema (ZIO). Zymosan injection at the ankle joint caused swelling and coincided with histological joint alterations and IL-17A expression in areas with cell...

Toll-like receptor 2 agonist exacerbates renal injury in diabetic mice.

Experimental and therapeutic medicine

Li F, Zhang N, Li Z, Deng L, Zhang J, Zhou Y.
PMID: 28352321
Exp Ther Med. 2017 Feb;13(2):495-502. doi: 10.3892/etm.2017.4031. Epub 2017 Jan 05.

Inflammation is implicated in the pathogenesis of diabetic nephropathy (DN). Toll-like receptor 2 (TLR2) is a ligand-activated membrane-bound receptor, which induces an inflammatory response, thus serving a crucial role in the pathogenesis of DN. The present study aimed to...

Spontaneous bacterial peritonitis: The clinical challenge of a leaky gut and a cirrhotic liver.

World journal of hepatology

Lutz P, Nischalke HD, Strassburg CP, Spengler U.
PMID: 25848460
World J Hepatol. 2015 Mar 27;7(3):304-14. doi: 10.4254/wjh.v7.i3.304.

Spontaneous bacterial peritonitis (SBP) is a frequent, life-threatening bacterial infection in patients with liver cirrhosis and ascites. Portal hypertension leads to increased bacterial translocation from the intestine. Failure to eliminate invading pathogens due to immune defects associated with advanced...

Modulation of Toll Like Receptor-2 on sebaceous gland by the treatment of adult female acne.

Dermato-endocrinology

Rocha MAD, Guadanhim LRS, Sanudo A, Bagatin E.
PMID: 29484093
Dermatoendocrinol. 2017 Oct 04;9(1):e1361570. doi: 10.1080/19381980.2017.1361570. eCollection 2017.

Adult female acne is a chronic inflammatory, immune-mediated disease that affects the pilosebaceous unit in women in their 20s to 40s, and is considered different from acne vulgaris.

Toll-like receptor 2 promotes neurogenesis from the dentate gyrus after photothrombotic cerebral ischemia in mice.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Seong KJ, Kim HJ, Cai B, Kook MS, Jung JY, Kim WJ.
PMID: 29520167
Korean J Physiol Pharmacol. 2018 Mar;22(2):145-153. doi: 10.4196/kjpp.2018.22.2.145. Epub 2018 Feb 23.

The subgranular zone (SGZ) of hippocampal dentate gyrus (HDG) is a primary site of adult neurogenesis. Toll-like receptors (TLRs), are involved in neural system development of

Estrogen receptor-alpha mediates Toll-like receptor-2 agonist-induced monocyte chemoattractant protein-1 production in mesangial cells.

Results in immunology

Dasgupta S, Eudaly J.
PMID: 24371584
Results Immunol. 2012 Nov 10;2:196-203. doi: 10.1016/j.rinim.2012.10.002. eCollection 2012.

TLR2 agonists are well known for inducing NF-kB activation and inflammation, while estrogen receptor-alpha (ER-α) is a regulator of estrogen-mediated anti-inflammatory responses. In the present work, we determined the role of ER-α and phosphorylated ER-α in TLR2 agonist-induced MCP1...

A new Vitreoscilla filiformis extract grown on spa water-enriched medium activates endogenous cutaneous antioxidant and antimicrobial defenses through a potential Toll-like receptor 2/protein kinase C, zeta transduction pathway.

Clinical, cosmetic and investigational dermatology

Mahe YF, Perez MJ, Tacheau C, Fanchon C, Martin R, Rousset F, Seite S.
PMID: 24039440
Clin Cosmet Investig Dermatol. 2013 Aug 30;6:191-6. doi: 10.2147/CCID.S47324. eCollection 2013.

Vitreoscilla filiformis (VF) biomass (VFB) has been widely used in cosmetic preparations and shown to modulate the major inducible free-radical scavenger mitochondrial superoxide dismutase in skin cells. By adding La Roche-Posay (LRP) thermal spring water to the VF culture...

Interactions between alveolar epithelial cells and neutrophils under pro-inflammatory conditions.

European clinical respiratory journal

von Schéele I, Larsson K, Palmberg L.
PMID: 26557246
Eur Clin Respir J. 2014 Sep 25;1. doi: 10.3402/ecrj.v1.24545. eCollection 2014.

BACKGROUND: Intercellular communication is essential for defense and survival of the organism. The aim of the study was to find out whether there is an active crosstalk between airway cells constituting the first line of defense, alveolar epithelial cells...

Sequence analysis of the Toll-like receptor 2 gene of old world camels.

Journal of advanced research

Dahiya SS, Nagarajan G, Bharti VK, Swami SK, Mehta SC, Tuteja FC, Narnaware SD, Patil N.
PMID: 25685538
J Adv Res. 2014 Nov;5(6):695-704. doi: 10.1016/j.jare.2013.09.001. Epub 2013 Sep 10.

The Toll-like receptor 2 (TLR2) gene of old world camels (Camelus dromedarius and Camelus bactrianus) was cloned and sequenced. The TLR2 gene of the dromedary camel had the highest nucleotide and amino acid identity with pig, i.e., 66.8% and...

Penehyclidine ameliorates acute lung injury by inhibiting Toll-like receptor 2/4 expression and nuclear factor-κB activation.

Experimental and therapeutic medicine

Wang NA, Su Y, Che XM, Zheng H, Shi ZG.
PMID: 27168812
Exp Ther Med. 2016 May;11(5):1827-1832. doi: 10.3892/etm.2016.3154. Epub 2016 Mar 11.

The aim of the present study was to investigate the effect of penehyclidine (PHC) on endotoxin-induced acute lung injury (ALI), as well as to examine the mechanism underlying this effect. A total of 60 rats were randomly divided into...

Fungal cell wall agents and bacterial lipopolysaccharide in organic dust as possible risk factors for pulmonary sarcoidosis.

Journal of occupational medicine and toxicology (London, England)

Stopinšek S, Ihan A, Salobir B, Terčelj M, Simčič S.
PMID: 27688795
J Occup Med Toxicol. 2016 Sep 21;11:46. doi: 10.1186/s12995-016-0135-4. eCollection 2016.

BACKGROUND: Composition of organic dust is very complex, involving particles of microbial, animal and plant origin. Several environmental exposure studies associate microbial cell wall agents in organic dust with various respiratory symptoms and diseases. The aim of the present...

Showing 1 to 12 of 348 entries