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Showing 1 to 12 of 114 entries
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Early Implementation of THAM for ICP Control: Therapeutic Hypothermia Avoidance and Reduction in Hypertonics/Hyperosmotics.

Case reports in critical care

Zeiler FA, Gillman LM, Teitelbaum J, West M.
PMID: 25544901
Case Rep Crit Care. 2014;2014:139342. doi: 10.1155/2014/139342. Epub 2014 Dec 04.

Background. Tromethamine (THAM) has been demonstrated to reduce intracranial pressure (ICP). Early consideration for THAM may reduce the need for other measures for ICP control. Objective. To describe 4 cases of early THAM therapy for ICP control and highlight...

Formulation and evaluation of controlled porosity osmotic pump for oral delivery of ketorolac.

Journal of basic and clinical pharmacy

Dasankoppa FS, Ningangowdar M, Sholapur H.
PMID: 24808662
J Basic Clin Pharm. 2012 Dec;4(1):2-9. doi: 10.4103/0976-0105.109398.

BACKGROUND: The osmotic drug delivery systems suitable for oral administration typically consist of a compressed tablet core that is coated with a semipermeable membrane that has an orifice drilled on it by means of a laser beam or mechanical...

Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery.

Indian journal of pharmaceutical sciences

Paliwal SK, Chauhan R, Sharma V, Majumdar DK, Paliwal S.
PMID: 20376226
Indian J Pharm Sci. 2009 Nov;71(6):687-91. doi: 10.4103/0250-474X.59555.

The most common method for applying a drug in to the eye is to formulate the drug in the form of an eye drop, but this method is not considered ideal for ocular delivery of drug because of poor...

Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery.

Clinical ophthalmology (Auckland, N.Z.)

Elsawy MF, Badawi N, Khairy HA.
PMID: 23836953
Clin Ophthalmol. 2013;7:1245-9. doi: 10.2147/OPTH.S39188. Epub 2013 Jun 24.

OBJECTIVE: To evaluate the prophylactic role of topical non-steroidal anti-inflammatory drugs in reducing the incidence of central macular edema (CME) in diabetic eyes post-cataract surgery.PATIENTS AND METHODS: This study included 86 eyes (70 patients) with high risk characteristics for...

Ketorolac tromethamine and ketoprofen suppositories: release profiles and bioavailability of a cocoa butter base formula in rabbits.

International journal of pharmaceutical compounding

Zia H, Rashed SF, Quadir M, Needham TE, Squillante E.
PMID: 23989705
Int J Pharm Compd. 1998 Sep-Oct;2(5):390-3.

Ketorolac tromethamine suppositories (30 mg) and ketoprofen suppositories (50 mg) were made by the fusion method with various bases such as cocoa butter, Witepsol H15, Witepsol W25, Witepsol W35, Witepsol E75, Suppocire AML and Hydrokote AP5-1. Also, ketorolac tromethamine...

Soft tissue injections in the athlete.

Sports health

Nepple JJ, Matava MJ.
PMID: 23015899
Sports Health. 2009 Sep;1(5):396-404. doi: 10.1177/1941738109343159.

BACKGROUND: Injections into or adjacent to soft tissue structures, including muscle, tendon, bursa, and fascia, for pain relief and an earlier return to play have become common in the field of sports medicine.STUDY DESIGN: Clinical review.RESULTS: Corticosteroids, local anesthetics,...

Analgesic properties of dexketoprofen trometamol.

Pain management

Walczak JS.
PMID: 24645708
Pain Manag. 2011 Sep;1(5):409-16. doi: 10.2217/pmt.11.42.

SUMMARY Dexketoprofen trometamol is the dextrorotary enantiomer of the NSAID ketoprofen formulated as a tromethamine salt. The purpose of administering 50% of the racemic mixture is to keep the same analgesic and anti-inflammatory effect while reducing the adverse events...

Novel in-situ gel for intravesical administration of ketorolac.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Sherif AY, Mahrous GM, Alanazi FK.
PMID: 30202226
Saudi Pharm J. 2018 Sep;26(6):845-851. doi: 10.1016/j.jsps.2018.03.014. Epub 2018 Mar 27.

The urinary bladder stores urine until the time of urination. Systemic administration of drugs to treat bladder diseases faces several limitations. Therefore, intravesical drug delivery is a promising alternative route of administration. An in-situ gel is used to form...

Is it melanoma-associated retinopathy or drug toxicity? Bilateral cystoid macular edema posing a diagnostic and therapeutic dilemma.

American journal of ophthalmology case reports

Patel SR, Moysidis SN, Koulisis N, Storey PP, Kashani AH, Rao NA, Rodger DC.
PMID: 29780921
Am J Ophthalmol Case Rep. 2018 Jan 31;10:77-80. doi: 10.1016/j.ajoc.2018.01.030. eCollection 2018 Jun.

PURPOSE: To report the clinical presentation, multimodal imaging, and management of a patient with metastatic melanoma who presented with cystoid macular edema (CME).OBSERVATIONS: We report a case of a 71-year-old Caucasian male with metastatic melanoma who presented with bilateral...

Medications Used for Prevention and Treatment of Postoperative Endodontic Pain: A Systematic Review.

European endodontic journal

Santini M, Da Rosa RA, Ferreira MB, Barletta F, Longo do Nascimento A, Weissheimer T, Estrela C, So MV.
PMID: 33609020
Eur Endod J. 2021 Apr;6(1):15-24. doi: 10.14744/eej.2020.85856. Epub 2021 Feb 02.

OBJECTIVE: Prevention and management of postoperative endodontic pain is a common challenge for the endodontists. This systematic review was conducted to evaluate the efficacy and safety of medicament therapeutic protocols in the prevention and management of endodontic pain.METHODS: A...

[Allergic reactions to COVID-19 vaccines: evidence and practice-oriented approach].

Der Internist

Klimek L, Eckrich J, Hagemann J, Casper I, Huppertz J.
PMID: 33580823
Internist (Berl). 2021 Mar;62(3):326-332. doi: 10.1007/s00108-021-00959-5. Epub 2021 Feb 13.

Less than a year after the first detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), vaccines have been approved for routine use in numerous countries and have already been used in mass vaccination programs. Vaccines include the mRNA...

Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial.

JAMA ophthalmology

Erichsen JH, Holm LM, Forslund Jacobsen M, Forman JL, Kessel L.
PMID: 34383010
JAMA Ophthalmol. 2021 Oct 01;139(10):1062-1070. doi: 10.1001/jamaophthalmol.2021.2976.

IMPORTANCE: The choice of anti-inflammatory prophylaxis parallel to cataract surgery is important for patient safety and successful outcome of surgery, but which regimen to choose is contested.OBJECTIVES: To determine whether a combination of prednisolone and nonsteroidal anti-inflammatory drug (NSAID)...

Showing 1 to 12 of 114 entries