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Showing 1 to 12 of 14 entries
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Comparative genomics of cryptosporidium.

International journal of genomics

Mazurie AJ, Alves JM, Ozaki LS, Zhou S, Schwartz DC, Buck GA.
PMID: 23738321
Int J Genomics. 2013;2013:832756. doi: 10.1155/2013/832756. Epub 2013 May 02.

Until recently, the apicomplexan parasites, Cryptosporidium hominis and C. parvum, were considered the same species. However, the two parasites, now considered distinct species, exhibit significant differences in host range, infectivity, and pathogenicity, and their sequenced genomes exhibit only 95-97%...

Characterization and functional properties of gastric tissue-resident memory T cells from children, adults, and the elderly.

Frontiers in immunology

Booth JS, Toapanta FR, Salerno-Goncalves R, Patil S, Kader HA, Safta AM, Czinn SJ, Greenwald BD, Sztein MB.
PMID: 24995010
Front Immunol. 2014 Jun 19;5:294. doi: 10.3389/fimmu.2014.00294. eCollection 2014.

T cells are the main orchestrators of protective immunity in the stomach; however, limited information on the presence and function of the gastric T subsets is available mainly due to the difficulty in recovering high numbers of viable cells...

Metal-Enhanced Fluorescence from Nanoparticulate Zinc Films.

The journal of physical chemistry. C, Nanomaterials and interfaces

Aslan K, Previte MJ, Zhang Y, Geddes CD.
PMID: 19946356
J Phys Chem C Nanomater Interfaces. 2008 Nov 27;112(47):18368-18375. doi: 10.1021/jp806790u.

A detailed study of metal-enhanced fluorescence (MEF) from fluorophores in the blue-to- red spectral region placed in close proximity to thermally evaporated zinc nanostructured films is reported. The zinc nanostructured films were deposited onto glass microscope slides as individual...

Bioinformatic and mass spectrometry identification of Anaplasma phagocytophilum proteins translocated into host cell nuclei.

Frontiers in microbiology

Sinclair SH, Garcia-Garcia JC, Dumler JS.
PMID: 25705208
Front Microbiol. 2015 Feb 06;6:55. doi: 10.3389/fmicb.2015.00055. eCollection 2015.

Obligate intracellular bacteria have an arsenal of proteins that alter host cells to establish and maintain a hospitable environment for replication. Anaplasma phagocytophilum secrets Ankyrin A (AnkA), via a type IV secretion system, which translocates to the nucleus of...

Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection.

Frontiers in immunology

Booth JS, Salerno-Goncalves R, Blanchard TG, Patil SA, Kader HA, Safta AM, Morningstar LM, Czinn SJ, Greenwald BD, Sztein MB.
PMID: 26441971
Front Immunol. 2015 Sep 17;6:466. doi: 10.3389/fimmu.2015.00466. eCollection 2015.

Mucosal-associated invariant T (MAIT) cells represent a class of antimicrobial innate-like T cells that have been characterized in human blood, liver, lungs, and intestine. Here, we investigated, for the first time, the presence of MAIT cells in the stomach...

Conversion of just-continuous metallic films to large particulate substrates for metal-enhanced fluorescence.

Journal of applied physics

Aslan K, Malyn SN, Zhang Y, Geddes CD.
PMID: 19479004
J Appl Phys. 2008 Apr 15;103(8):84307-843077. doi: 10.1063/1.2905319. Epub 2008 Apr 25.

We report the effects of thermally annealing, non-, just-, and thick continuous silver films for their potential applications in metal-enhanced fluorescence, a near-field concept which can alter the free-space absorption and emissive properties of close-proximity fluorophores (excited states). We...

Genomic profiling of host responses to Lassa virus: therapeutic potential from primate to man.

Future virology

Zapata JC, Salvato MS.
PMID: 25844088
Future Virol. 2015 Mar 13;10(3):233-256. doi: 10.2217/fvl.15.1.

Lassa virus infection elicits distinctive changes in host gene expression and metabolism. We focus on changes in host gene expression that may be biomarkers that discriminate individual pathogens or may help to provide a prognosis for disease. In addition...

Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, .

Journal of clinical & experimental cardiology

Qureshi AA, Khan DA, Mahjabeen W, Papasian CJ, Qureshi N.
PMID: 24319627
J Clin Exp Cardiolog. 2013 Mar 02;4(3). doi: 10.4172/2155-9880.1000238.

BACKGROUND: Age-associated altered redox imbalances and dysregulated immune function, contribute to the development of a variety of age associated diseases. Inflammatory markers and lipid profiles are useful prognostic indicators of a variety of age-associated and cardiovascular diseases. We have...

Directional, Broad, and Fixed Angle Surface Plasmon Coupled Fluorescence from Iron Thin Films.

The journal of physical chemistry. C, Nanomaterials and interfaces

Aslan K, Zhang Y, Geddes CD.
PMID: 20657700
J Phys Chem C Nanomater Interfaces. 2009 Nov 09;113(48):20535-20538. doi: 10.1021/jp907510m.

Fixed angle surface plasmon coupled fluorescence (SPCF) from iron thin films is demonstrated for the first time. The optimum thickness of the iron thin films was determined to be 15 nm using Fresnel calculations. The angles of minimum reflectivity...

Clostridium difficile contains plasmalogen species of phospholipids and glycolipids.

Biochimica et biophysica acta

Guan Z, Katzianer D, Zhu J, Goldfine H.
PMID: 24983203
Biochim Biophys Acta. 2014 Oct;1842(10):1353-9. doi: 10.1016/j.bbalip.2014.06.011. Epub 2014 Jun 28.

Analysis of the polar lipids of many pathogenic and non-pathogenic clostridia has revealed the presence of plasmalogens, alk-1'-enyl ether-containing phospholipids and glycolipids. An exception to this finding so far has been Clostridium difficile, an important human pathogen which is...

Bacterial superantigen toxins induce a lethal cytokine storm by enhancing B7-2/CD28 costimulatory receptor engagement, a critical immune checkpoint.

Receptors & clinical investigation

Kaempfer R, Popugailo A, Levy R, Arad G, Hillman D, Rotfogel Z.
PMID: 28286804
Receptors Clin Investig. 2017;4(1). Epub 2017 Jan 30.

Formation of the costimulatory axis between the B7-2 and CD28 coreceptors is critical for T-cell activation. Superantigens, Gram-positive bacterial virulence factors, cause toxic shock and sepsis by hyperinducing inflammatory cytokines. We report a novel role for costimulatory receptors CD28...

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections.

Viruses

Xiao Y, Isaacs SN.
PMID: 21197387
Viruses. 2010 Oct;2(10):2381-2403. doi: 10.3390/v2102381.

Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health. The current licensed live vaccinia virus-based smallpox vaccine is extremely effective as a prophylactic vaccine to...

Showing 1 to 12 of 14 entries