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Showing 1 to 12 of 32 entries
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Expression of estrogen receptor, progesterone receptor, and Ki67 in normal breast tissue in relation to subsequent risk of breast cancer.

NPJ breast cancer

Oh H, Eliassen AH, Wang M, Smith-Warner SA, Beck AH, Schnitt SJ, Collins LC, Connolly JL, Montaser-Kouhsari L, Polyak K, Tamimi RM.
PMID: 28111631
NPJ Breast Cancer. 2016;2. doi: 10.1038/npjbcancer.2016.32. Epub 2016 Oct 26.

Although expression of estrogen receptor (ER), progesterone receptor (PR), and cell proliferation marker Ki67 serve as predictive and prognostic factors in breast cancers, little is known about their roles in normal breast tissue. Here in a nested case-control study...

Evidence of differential effects of vitamin d receptor variants on epithelial ovarian cancer risk by predicted vitamin d status.

Frontiers in oncology

Prescott J, Bertrand KA, Reid BM, Permuth-Wey J, De Vivo I, Cramer DW, Terry KL, Tworoger SS.
PMID: 25368842
Front Oncol. 2014 Oct 20;4:286. doi: 10.3389/fonc.2014.00286. eCollection 2014.

INTRODUCTION: Experimental studies suggest vitamin D inhibits ovarian carcinogenesis. Yet, epidemiologic studies of ovarian cancer risk and lifestyle correlates of vitamin D status, plasma 25-hydroxyvitamin D [25(OH)D], or vitamin D receptor (VDR) variants have been inconsistent.OBJECTIVE: To evaluate VDR...

Commentary on "A meta-analysis but not a systematic review: an evaluation of the Global BMI Mortality Collaboration".

Journal of clinical epidemiology

Bhupathiraju SN, Di Angelantonio E, Danesh J, Hu FB.
PMID: 28411079
J Clin Epidemiol. 2017 Aug;88:30-32. doi: 10.1016/j.jclinepi.2017.04.006. Epub 2017 Apr 12.

No abstract available.

Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women.

NPJ breast cancer

Zeleznik OA, Balasubramanian R, Zhao Y, Frueh L, Jeanfavre S, Avila-Pacheco J, Clish CB, Tworoger SS, Eliassen AH.
PMID: 34006878
NPJ Breast Cancer. 2021 May 18;7(1):54. doi: 10.1038/s41523-021-00262-4.

Known modifiable risk factors account for a small fraction of premenopausal breast cancers. We investigated associations between pre-diagnostic circulating amino acid and amino acid-related metabolites (N = 207) and risk of breast cancer among predominantly premenopausal women of the...

Central Adiposity and Subsequent Risk of Breast Cancer by Menopause Status.

Journal of the National Cancer Institute

Houghton SC, Eliassen H, Tamimi RM, Willett WC, Rosner BA, Hankinson SE.
PMID: 33367714
J Natl Cancer Inst. 2021 Jul 01;113(7):900-908. doi: 10.1093/jnci/djaa197.

BACKGROUND: Increased body mass index (BMI) is associated with higher postmenopausal breast cancer risk and lower premenopausal breast cancer risk. Less is known about the central adiposity-breast cancer risk association, particularly for tumor subtypes.METHODS: We used prospective waist (WC)...

Contribution of socioeconomic and environmental factors to geographic disparities in breast cancer risk in the Nurses' Health Study II.

Environmental epidemiology (Philadelphia, Pa.)

Vieira VM, VoPham T, Bertrand KA, James P, DuPré N, Tamimi RM, Laden F, Hart JE.
PMID: 33344878
Environ Epidemiol. 2020 Feb;4(1). doi: 10.1097/ee9.0000000000000080. Epub 2019 Dec 12.

BACKGROUND: Evidence of geographic disparities in breast cancer incidence within the U.S. and spatial analyses can provide insight into the potential contribution of environmental exposures or other geographically-varying factors to these disparities.METHODS: We applied generalized additive models (GAMs) to...

Discovery and Features of an Alkylating Signature in Colorectal Cancer.

Cancer discovery

Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, Fuchs CS, Wu K, Ogino S, Giannakis M.
PMID: 34140290
Cancer Discov. 2021 Oct;11(10):2446-2455. doi: 10.1158/2159-8290.CD-20-1656. Epub 2021 Jun 17.

Several risk factors have been established for colorectal cancer, yet their direct mutagenic effects in patients' tumors remain to be elucidated. Here, we leveraged whole-exome sequencing data from 900 colorectal cancer cases that had occurred in three U.S.-wide prospective...

Androgen receptor expression in normal breast tissue and subsequent breast cancer risk.

NPJ breast cancer

Kensler KH, Beca F, Baker GM, Heng YJ, Beck AH, Schnitt SJ, Hazra A, Rosner BA, Eliassen AH, Hankinson SE, Brown M, Tamimi RM.
PMID: 30276234
NPJ Breast Cancer. 2018 Sep 21;4:33. doi: 10.1038/s41523-018-0085-3. eCollection 2018.

Sex steroid hormone signaling is critical in the development of breast cancers, although the role of the androgen receptor remains unclear. This study evaluated androgen receptor (AR) expression in normal breast tissue as a potential marker of breast cancer...

Diet, lifestyle, and genetic risk factors for type 2 diabetes: a review from the Nurses' Health Study, Nurses' Health Study 2, and Health Professionals' Follow-up Study.

Current nutrition reports

Ardisson Korat AV, Willett WC, Hu FB.
PMID: 25599007
Curr Nutr Rep. 2014 Dec 01;3(4):345-354. doi: 10.1007/s13668-014-0103-5.

The epidemiological evidence collected from three large US cohorts (Nurses' Health Study, Nurses' Health Study 2, and Health Professionals' Follow-up Study) has yielded important information regarding the roles of overall diet, individual foods and nutrients, physical activity and other...

Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Fortner RT, Rice MS, Knutsen SF, Orlich MJ, Visvanathan K, Patel AV, Gaudet MM, Tjønneland A, Kvaskoff M, Kaaks R, Trichopolou A, Pala V, Onland-Moret NC, Gram IT, Amiano P, Idahl A, Allen NE, Weiderpass E, Poynter JN, Robien K, Giles GG, Milne RL, Setiawan VW, Merritt MA, van den Brandt PA, Zeleniuch-Jacquotte A, Arslan AA, O'Brien KM, Sandler DP, Wolk A, Håkansson N, Harris HR, Trabert B, Wentzensen N, Tworoger SS, Schouten LJ.
PMID: 32732252
Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):2010-2018. doi: 10.1158/1055-9965.EPI-20-0354. Epub 2020 Jul 30.

BACKGROUND: Epithelial ovarian, fallopian tube, and primary peritoneal cancers have shared developmental pathways. Few studies have prospectively examined heterogeneity in risk factor associations across these three anatomic sites.METHODS: We identified 3,738 ovarian, 337 peritoneal, and 176 fallopian tube incident...

Changes in nut consumption influence long-term weight change in US men and women.

BMJ nutrition, prevention & health

Liu X, Li Y, Guasch-Ferré M, Willett WC, Drouin-Chartier JP, Bhupathiraju SN, Tobias DK.
PMID: 33235963
BMJ Nutr Prev Health. 2019 Sep 23;2(2):90-99. doi: 10.1136/bmjnph-2019-000034. eCollection 2019.

BACKGROUND: Nut consumption has increased in the US but little evidence exists on the association between changes in nut consumption and weight change. We aimed to evaluate the association between changes in total consumption of nuts and intakes of...

Development and validation of empirical indices to assess the insulinaemic potential of diet and lifestyle.

The British journal of nutrition

Tabung FK, Wang W, Fung TT, Hu FB, Smith-Warner SA, Chavarro JE, Fuchs CS, Willett WC, Giovannucci EL.
PMID: 27821188
Br J Nutr. 2016 Nov 08;1-12. doi: 10.1017/S0007114516003755. Epub 2016 Nov 08.

The glycaemic and insulin indices assess postprandial glycaemic and insulin response to foods, respectively, which may not reflect the long-term effects of diet on insulin response. We developed and evaluated the validity of four empirical indices to assess the...

Showing 1 to 12 of 32 entries