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Showing 1 to 12 of 657 entries
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Platelet-derived growth factor-C promotes human melanoma aggressiveness through activation of neuropilin-1.

Oncotarget

Ruffini F, Levati L, Graziani G, Caporali S, Atzori MG, D'Atri S, Lacal PM.
PMID: 28977999
Oncotarget. 2017 Jun 27;8(40):66833-66848. doi: 10.18632/oncotarget.18706. eCollection 2017 Sep 15.

Despite recent progress in advanced melanoma therapy, identification of signalling pathways involved in melanoma switch from proliferative to invasive states is still crucial to uncover new therapeutic targets for improving the outcome of metastatic disease. Neuropilin-1 (NRP-1), a co-receptor...

The expression of vasohibin-1 and its prognostic significance in bladder cancer.

Experimental and therapeutic medicine

Zhang B, Wu Z, Xie W, Tian D, Chen F, Qin C, Du Z, Tang G, Gao Q, Qiu X, Wu C, Tian J, Hu H.
PMID: 29042936
Exp Ther Med. 2017 Oct;14(4):3477-3484. doi: 10.3892/etm.2017.4969. Epub 2017 Aug 18.

Angiogenesis is important in the development of solid tumors. Vasohibin-1 (VASH-1) is an endothelium-derived protein that acts as an inhibitor of angiogenesis in many different types of cancer. However, the expression of VASH-1 and its clinical value in bladder...

Variations in inflammatory genes are associated with periodontitis.

Immunity & ageing : I & A

Ianni M, Bruzzesi G, Pugliese D, Porcellini E, Carbone I, Schiavone A, Licastro F.
PMID: 24274085
Immun Ageing. 2013 Oct 01;10(1):39. doi: 10.1186/1742-4933-10-39.

BACKGROUND: Periodontitis is a multi-factorial disease and several risk-factors such as infections, inflammatory responses, oral hygiene, smoke, aging and individual predisposition are involved in the disease. Pathogens trigger chronic inflammation with cytokines release which in turn leads to the...

Vascular endothelial growth factor receptor-1 expression in breast cancer and its correlation to vascular endothelial growth factor a.

International journal of breast cancer

Srabovic N, Mujagic Z, Mujanovic-Mustedanagic J, Softic A, Muminovic Z, Rifatbegovic A, Begic L.
PMID: 24416596
Int J Breast Cancer. 2013;2013:746749. doi: 10.1155/2013/746749. Epub 2013 Dec 12.

VEGF-A is the most potent angiogenic factor in tumour angiogenesis. Its effects are mediated via two receptors VEGFR-1 and VEGFR-2. Primary aim of our study was to examine the expression of VEGFR-1 in breast cancer and its correlation to...

Anti-vascular endothelial growth factor therapy for diabetic macular edema.

Therapeutic advances in endocrinology and metabolism

Boyer DS, Hopkins JJ, Sorof J, Ehrlich JS.
PMID: 24324855
Ther Adv Endocrinol Metab. 2013 Dec;4(6):151-69. doi: 10.1177/2042018813512360.

Diabetes mellitus is a serious health problem that affects over 350 million individuals worldwide. Diabetic retinopathy (DR), which is the most common microvascular complication of diabetes, is the leading cause of new cases of blindness in working-aged adults. Diabetic...

Differential expression of vascular endothelial growth factor-A, -C and -D for the diagnosis and prognosis of cancer patients with malignant effusions.

Oncology letters

Jia L, DU Y, Li T, Lv Y, Wang Y, Zhang Y, Zhou X, Liu W.
PMID: 26622551
Oncol Lett. 2015 Aug;10(2):667-674. doi: 10.3892/ol.2015.3305. Epub 2015 Jun 02.

Elevated levels of vascular endothelial growth factor (VEGF) contribute to angiogenesis and serous cavity effusions. The present study evaluated the diagnostic and prognostic values of VEGF-A, -C and -D proteins in the serum, supernatant fluid and exfoliated cells of...

Plasma growth differentiation factor 15 is associated with weight loss and mortality in cancer patients.

Journal of cachexia, sarcopenia and muscle

Lerner L, Hayes TG, Tao N, Krieger B, Feng B, Wu Z, Nicoletti R, Chiu MI, Gyuris J, Garcia JM.
PMID: 26672741
J Cachexia Sarcopenia Muscle. 2015 Dec;6(4):317-24. doi: 10.1002/jcsm.12033. Epub 2015 Apr 30.

BACKGROUND: Cancer-related weight loss is associated with increased inflammation and decreased survival. The novel inflammatory mediator growth differentiation factor (GDF)15 is associated with poor prognosis in cancer but its role in cancer-related weight loss (C-WL) remains unclear. Our objective...

Pharmacological treatment with diacerein combined with mechanical stimulation affects the expression of growth factors in human chondrocytes.

Biochemistry and biophysics reports

Steinecker-Frohnwieser B, Kaltenegger H, Weigl L, Mann A, Kullich W, Leithner A, Lohberger B.
PMID: 28955780
Biochem Biophys Rep. 2017 Jul 01;11:154-160. doi: 10.1016/j.bbrep.2017.06.006. eCollection 2017 Sep.

BACKGROUND: Osteoarthritis (OA) as the main chronic joint disease arises from a disturbed balance between anabolic and catabolic processes leading to destructions of articular cartilage of the joints. While mechanical stress can be disastrous for the metabolism of chondrocytes,...

Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways.

Oncogenesis

Yang X, Shi B, Li L, Xu Z, Ge Y, Shi J, Liu Y, Zheng D.
PMID: 26950598
Oncogenesis. 2016 Mar 07;5:e206. doi: 10.1038/oncsis.2016.9.

Although death receptor 6 (DR6) is aberrantly expressed in certain cancer cell lines, its function, signaling pathway and potential clinical significance in tumor progression are not well characterized. We report here that knocking down DR6 in the mouse B16...

Osteogenesis from Dental Pulp Derived Stem Cells: A Novel Conditioned Medium Including Melatonin within a Mixture of Hyaluronic, Butyric, and Retinoic Acids.

Stem cells international

Maioli M, Basoli V, Santaniello S, Cruciani S, Delitala AP, Pinna R, Milia E, Grillari-Voglauer R, Fontani V, Rinaldi S, Muggironi R, Pigliaru G, Ventura C.
PMID: 26880937
Stem Cells Int. 2016;2016:2056416. doi: 10.1155/2016/2056416. Epub 2016 Jan 10.

Human dental pulp stem cells (hDPSCs) have shown relevant potential for cell therapy in the orthopedic and odontoiatric fields. The optimization of their osteogenic potential is currently a major challenge. Vascular endothelial growth factor A (VEGF A) has been...

Sustained-released mixture of vascular endothelial growth factor 165 and fibrin glue strengthens healing of ileal anastomoses in a rabbit model with intraperitoneal infection.

Annals of surgical treatment and research

Li Z, Wang W, Wang X, Jiang L, Wang F, Liu Q.
PMID: 28932732
Ann Surg Treat Res. 2017 Sep;93(3):159-165. doi: 10.4174/astr.2017.93.3.159. Epub 2017 Aug 30.

PURPOSE: To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses.METHODS: One hundred twenty-eight male and female New Zealand white rabbits underwent intraperitoneal...

Is vascular endothelial growth factor a useful biomarker in giant cell arteritis?.

RMD open

Goodfellow N, Morlet J, Singh S, Sabokbar A, Hutchings A, Sharma V, Vaskova J, Masters S, Zarei A, Luqmani R.
PMID: 28405470
RMD Open. 2017 Mar 29;3(1):e000353. doi: 10.1136/rmdopen-2016-000353. eCollection 2017.

OBJECTIVES: To assess the performance of circulating vascular endothelial growth factor (VEGF) levels as a tool for diagnosing giant cell arteritis (GCA) in a cohort of patients referred for assessment of suspected GCA.METHODS: We selected 298 patients recruited to...

Showing 1 to 12 of 657 entries