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Showing 1 to 12 of 488 entries
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Future developments in the pharmacotherapy of lung disease.

Pharmaceutisch weekblad. Scientific edition

Van der Kuy A.
PMID: 1437503
Pharm Weekbl Sci. 1992 Aug 21;14(4):221-3. doi: 10.1007/BF01962543.

Future advances in the pharmacotherapy of lung disease will occur mainly in the treatment of asthma, and will include the development of new long-acting beta 2-agonists, long-acting parasympatholytics, phosphodiesterase inhibitors, corticosteroids with fewer systemic side-effects, and other antiinflammatory drugs....

Systemic inflammation in COPD in relation to smoking status.

Multidisciplinary respiratory medicine

Serapinas D, Narbekovas A, Juskevicius J, Sakalauskas R.
PMID: 22958407
Multidiscip Respir Med. 2011 Aug 31;6(4):214-9. doi: 10.1186/2049-6958-6-4-214.

BACKGROUND AND AIMS: Smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) that has been recently defined as a systemic pulmonary inflammatory disease. However, the impact of smoking itself on systemic inflammation in...

Two single nucleotide polymorphisms sites in .

Journal of biological research (Thessalonike, Greece)

Guo XF, Hu WP, Lang XZ, Li QL, Wang XY, Di R, Liu QY, Liu XL, An YF, Chu MX.
PMID: 28413783
J Biol Res (Thessalon). 2017 Apr 13;24:8. doi: 10.1186/s40709-017-0065-z. eCollection 2017 Dec.

BACKGROUND: Alpha 1-antitrypsin (α1-AT) may affect the susceptibility of mastitis in dairy cattle for its possible role in the protection of lactoferrin from proteolytic degradation in the mammary. Milk somatic cell score (SCS) is a logarithmic transformation of the...

Alpha-1 Antitrypsin Prevents the Development of Preeclampsia Through Suppression of Oxidative Stress.

Frontiers in physiology

Feng Y, Xu J, Zhou Q, Wang R, Liu N, Wu Y, Yuan H, Che H.
PMID: 27303303
Front Physiol. 2016 May 24;7:176. doi: 10.3389/fphys.2016.00176. eCollection 2016.

Preeclampsia (PE) and its complications have become the leading cause of maternal and fetal morbidity and mortality in the world. And the development of PE is still barely predictable and thus challenging to prevent and manage clinically. Oxidative stress...

Emphysema and COPD in a young woman.

Respiratory medicine case reports

Conroy K, Miller G, Shipley M.
PMID: 26029541
Respir Med Case Rep. 2014 Apr 26;12:50-1. doi: 10.1016/j.rmcr.2014.03.003. eCollection 2014.

A 28-year old woman presented with a progressive cough and breathlessness. She had a family history of early onset COPD. Spirometry demonstrated airflow obstruction with no reversibility. An HRCT showed extensive centrolobular emphysema with an upper lobe predominance. Blood...

Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry.

Laboratory animal research

Ahn JY, Kim IY, Oh SJ, Hwang HS, Yi SS, Kim YN, Shin JH, Yoon YS, Seong JK.
PMID: 24999358
Lab Anim Res. 2014 Jun;30(2):45-53. doi: 10.5625/lar.2014.30.2.45. Epub 2014 Jun 23.

Pig pancreas may be a therapeutic resource for human diabetic patients. However, this potential is hindered by a lack of knowledge of the molecular events of pig pancreas development. In this study, the embryonic day 60, neonate and 6-month...

Images in COPD: Alpha-1 Antitrypsin Deficiency and Bronchiectasis.

Chronic obstructive pulmonary diseases (Miami, Fla.)

Simpson S, Kueppers F, Steiner RM.
PMID: 28848885
Chronic Obstr Pulm Dis. 2016 Apr 07;3(2):601-604. doi: 10.15326/jcopdf.3.2.2016.0143.

No abstract available.

Current and Emerging Treatments for Alpha-1 Antitrypsin Deficiency.

Gastroenterology & hepatology

Perlmutter DH.
PMID: 27489528
Gastroenterol Hepatol (N Y). 2016 Jul;12(7):446-8.

No abstract available.

A panel of glycoproteins as candidate biomarkers for early diagnosis and treatment evaluation of B-cell acute lymphoblastic leukemia.

Biomarker research

Cavalcante Mde S, Torres-Romero JC, Lobo MD, Moreno FB, Bezerra LP, Lima DS, Matos JC, Moreira Rde A, Monteiro-Moreira AC.
PMID: 26823978
Biomark Res. 2016 Jan 27;4:1. doi: 10.1186/s40364-016-0055-6. eCollection 2016.

BACKGROUND: Acute lymphoblastic leukemia is the most common malignant cancer in childhood. The signs and symptoms of childhood cancer are difficult to recognize, as it is not the first diagnosis to be considered for nonspecific complaints, leading to potential...

Alpha 1 antitrypsin deficiency in infants with neonatal cholestasis.

Iranian journal of pediatrics

Monajemzadeh M, Shahsiah R, Vasei M, Tanzifi P, Rezaei N, Najafi M, Soleimanifar N, Eghbali M.
PMID: 24800007
Iran J Pediatr. 2013 Oct;23(5):501-7.

OBJECTIVE: Alpha1-antitrypsin deficiency (A1ATD) is the most important indication for liver transplantation in children. The gene frequencies vary in different ethnic groups. In the present study, we attempt to determine the frequencies of the most common defective alleles, Z...

The use of cytochemistry, immunophenotyping, flow cytometry, and in vitro differentiation to determine the ontogeny of a canine monoblastic leukemia.

Veterinary clinical pathology

Modiano JF, Smith R, Wojcieszyn J, Thomas JS, Rosenbaum BA, Ball C, Nicholds EA, Anthony MA, Barton CL.
PMID: 12075547
Vet Clin Pathol. 1998;27(2):40-49. doi: 10.1111/j.1939-165x.1998.tb01014.x.

We evaluated the utility of cytochemistry, immunophenotyping, flow cytometry, and in vitro culture with forced differentiation of leukemic cells as diagnostic aids to identify the malignant cell ontogeny in a dog with leukemia. A tentative diagnosis of monoblastic leukemia...

Increased prevalence of intestinal inflammation in patients with liver cirrhosis.

World journal of gastroenterology

Saitoh O, Sugi K, Lojima K, Matsumoto H, Nakagawa K, Kayazawa M, Tanaka S, Teranishi T, Hirata I, Katsu Ki.
PMID: 11819475
World J Gastroenterol. 1999 Oct;5(5):391-396. doi: 10.3748/wjg.v5.i5.391.

AIM:To investigate the pathophysiology of the digestive tract in patients with liver cirrhosis.METHODS:In 42 cirrhotic patients and 20 control subjects, the following fecal proteins were measured by enzyme-linked immunosorbent assay: albumin (Alb), transferrin (Tf), and alpha(1)antitrypsin (alpha(1)-AT) as a...

Showing 1 to 12 of 488 entries