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Endogenous viruses: Connecting recent and ancient viral evolution.

Virology

Aiewsakun P, Katzourakis A.
PMID: 25771486
Virology. 2015 May;479:26-37. doi: 10.1016/j.virol.2015.02.011. Epub 2015 Mar 12.

The rapid rates of viral evolution allow us to reconstruct the recent history of viruses in great detail. This feature, however, also results in rapid erosion of evolutionary signal within viral molecular data, impeding studies of their deep history....

Microarray-based sketches of the HERV transcriptome landscape.

PloS one

Pérot P, Mugnier N, Montgiraud C, Gimenez J, Jaillard M, Bonnaud B, Mallet F.
PMID: 22761958
PLoS One. 2012;7(6):e40194. doi: 10.1371/journal.pone.0040194. Epub 2012 Jun 28.

Human endogenous retroviruses (HERVs) are spread throughout the genome and their long terminal repeats (LTRs) constitute a wide collection of putative regulatory sequences. Phylogenetic similarities and the profusion of integration sites, two inherent characteristics of transposable elements, make it...

Unfixed endogenous retroviral insertions in the human population.

Journal of virology

Marchi E, Kanapin A, Magiorkinis G, Belshaw R.
PMID: 24920817
J Virol. 2014 Sep 01;88(17):9529-37. doi: 10.1128/JVI.00919-14. Epub 2014 Jun 11.

UNLABELLED: One lineage of human endogenous retroviruses (HERVs), HERV-K(HML2), is upregulated in many cancers, some autoimmune/inflammatory diseases, and HIV-infected cells. Despite 3 decades of research, it is not known if these viruses play a causal role in disease, and...

Showing 1 to 3 of 3 entries