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Showing 1 to 12 of 21 entries
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Antagonism of miRNA in heart failure: first evidence in human.

European heart journal

Baker AH, Giacca M.
PMID: 33338200
Eur Heart J. 2021 Jan 07;42(2):189-191. doi: 10.1093/eurheartj/ehaa967.

No abstract available.

Genetic Contribution to Common Heart Failure-Not So Rare?.

JAMA cardiology

McNally EM, O'Donnell CJ.
PMID: 33325982
JAMA Cardiol. 2021 Apr 01;6(4):387. doi: 10.1001/jamacardio.2020.6508.

No abstract available.

Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study.

Diabetes care

Mordi IR, Lumbers RT, Palmer CNA, Pearson ER, Sattar N, Holmes MV, Lang CC.
PMID: 34088700
Diabetes Care. 2021 Jul;44(7):1699-1705. doi: 10.2337/dc20-2518. Epub 2021 Jun 04.

OBJECTIVE: The aim of this study was to use Mendelian randomization (MR) techniques to estimate the causal relationships between genetic liability to type 2 diabetes (T2D), glycemic traits, and risk of heart failure (HF).RESEARCH DESIGN AND METHODS: Summary-level data...

Rare Diseases in Cardiovascular Medicine II.

European heart journal

Majid Akhtar M, Elliott PM.
PMID: 30052875
Eur Heart J. 2017 Jun 01;38(21):1629-1631. doi: 10.1093/eurheartj/ehx242.

No abstract available.

Genomes, proteomes, and the central dogma.

Circulation. Cardiovascular genetics

Franklin S, Vondriska TM.
PMID: 22010165
Circ Cardiovasc Genet. 2011 Oct;4(5):576. doi: 10.1161/CIRCGENETICS.110.957795.

Systems biology, with its associated technologies of proteomics, genomics, and metabolomics, is driving the evolution of our understanding of cardiovascular physiology. Rather than studying individual molecules or even single reactions, a systems approach allows integration of orthogonal data sets...

Epigenetic Regulation of Heart Failure: Cell Type Matters.

Circulation research

Padula SL, Yutzey KE.
PMID: 34292781
Circ Res. 2021 Jul 23;129(3):414-416. doi: 10.1161/CIRCRESAHA.121.319642. Epub 2021 Jul 22.

No abstract available.

Race-based therapeutics: a discussion surrounding heart failure trials.

JAAPA : official journal of the American Academy of Physician Assistants

Schmitz N.
PMID: 17319388
JAAPA. 2007 Feb;20(2):24-8. doi: 10.1097/01720610-200702000-00014.

No abstract available.

Cardiac remodeling and failure: from molecules to man (Part I).

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology

Fedak PW, Verma S, Weisel RD, Li RK.
PMID: 15710285
Cardiovasc Pathol. 2005 Jan-Feb;14(1):1-11. doi: 10.1016/j.carpath.2004.12.002.

The process of heart failure appears to be a common and coordinated response to cardiac injury and dysfunction. The contemporary mechanistic viewpoint that predictable, shared, highly regulated events underlie the complex heart failure process implies that an improved understanding...

Systems biology and heart failure: concepts, methods, and potential research applications.

Heart failure reviews

Adams KF.
PMID: 19396630
Heart Fail Rev. 2010 Jul;15(4):371-98. doi: 10.1007/s10741-009-9138-x.

Dramatic advances in molecular biology dominated twentieth century biomedical science and delineated the function of individual genes and molecules in exquisite detail. However, biological processes cannot be fully understood based on the properties of individual genes and molecules alone,...

Preface. Genetic studies of primary forms of heart failure.

Heart failure clinics

MacRae CA.
PMID: 20347782
Heart Fail Clin. 2010 Apr;6(2):xv-xvi. doi: 10.1016/j.hfc.2009.12.006.

No abstract available.

Perspective on precision medicine in paediatric heart failure.

Clinical science (London, England : 1979)

Fridman MD, Mital S.
PMID: 28265035
Clin Sci (Lond). 2017 Mar 01;131(6):439-448. doi: 10.1042/CS20160414.

In 2015, President Obama launched the Precision Medicine Initiative (PMI), which introduced new funding to a method of research with the potential to study rare and complex diseases. Paediatric heart failure, a heterogeneous syndrome affecting approximately 1 in 100000...

Heart failure entails significant changes in human nucleocytoplasmic transport gene expression.

International journal of cardiology

Molina-Navarro MM, Roselló-Lletí E, Tarazón E, Ortega A, Sánchez-Izquierdo D, Lago F, González-Juanatey JR, García-Pavía P, Salvador A, Montero JA, Portolés M, Rivera M.
PMID: 23651824
Int J Cardiol. 2013 Oct 03;168(3):2837-43. doi: 10.1016/j.ijcard.2013.03.192. Epub 2013 May 04.

BACKGROUND: Heart failure (HF) induces alterations in nucleocytoplasmic transport, which is essential to the cardiomyocyte biology. The objective of this study was to analyze the changes in gene expression in human HF, particularly focusing on nucleocytoplasmic transport-related genes.METHODS AND...

Showing 1 to 12 of 21 entries