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Kluth LA, Rink M, Ahyai SA, et al. Vorzeitiger Abbruch randomisierter kontrollierter Studien : Vorteilsbedingter Therapieeffekt. [Randomized controlled trials terminated prematurely: beneficial therapy effects]. Urologe A. 2013;52(8):1080-3doi: 10.1007/s00120-013-3144-2.
Kluth, L. A., Rink, M., Ahyai, S. A., Fisch, M., Shariat, S. F., & Dahm, P. (2013). Vorzeitiger Abbruch randomisierter kontrollierter Studien : Vorteilsbedingter Therapieeffekt. [Randomized controlled trials terminated prematurely: beneficial therapy effects]. Der Urologe. Ausg. A, 52(8), 1080-3. https://doi.org/10.1007/s00120-013-3144-2
Kluth, L A, et al. "Vorzeitiger Abbruch randomisierter kontrollierter Studien : Vorteilsbedingter Therapieeffekt." [Randomized controlled trials terminated prematurely: beneficial therapy effects]. Der Urologe. Ausg. A vol. 52,8 (2013): 1080-3. doi: https://doi.org/10.1007/s00120-013-3144-2
Kluth LA, Rink M, Ahyai SA, Fisch M, Shariat SF, Dahm P. Vorzeitiger Abbruch randomisierter kontrollierter Studien : Vorteilsbedingter Therapieeffekt. [Randomized controlled trials terminated prematurely: beneficial therapy effects]. Urologe A. 2013 Aug;52(8):1080-3. doi: 10.1007/s00120-013-3144-2. German. PMID: 23712423.
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Urologe A. 2013 Aug;52(8):1080-3. doi: 10.1007/s00120-013-3144-2.

[Randomized controlled trials terminated prematurely: beneficial therapy effects].

Der Urologe. Ausg. A

[Article in German]
L A Kluth, M Rink, S A Ahyai, M Fisch, S F Shariat, P Dahm

Affiliations

  1. Klinik für Urologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

PMID: 23712423 DOI: 10.1007/s00120-013-3144-2

Abstract

Randomized controlled trials (RCTs) stopped prematurely for beneficial therapy effects are becoming increasingly more prevalent in the urological literature and often receive great attention in the public and medical media. Urologists who practice evidence-based medicine should be aware of the potential bias and the different reasons why and how early termination of RCTs can and will affect the results. This review provides insights into the challenges clinical urologists face by interpreting the results of prematurely terminated RCTs.

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