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Yang JC, Sun Y, Xu CX, et al. Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study. Exp Ther Med. 2014;9(1):137-142doi: 10.3892/etm.2014.2068.
Yang, J. C., Sun, Y., Xu, C. X., Dang, Q. L., Li, L., Xu, Y. G., Song, Y. J., & Yan, H. (2015). Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study. Experimental and therapeutic medicine, 9(1), 137-142. https://doi.org/10.3892/etm.2014.2068
Yang, Jiang-Cun, et al. "Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study." Experimental and therapeutic medicine vol. 9,1 (2015): 137-142. doi: https://doi.org/10.3892/etm.2014.2068
Yang JC, Sun Y, Xu CX, Dang QL, Li L, Xu YG, Song YJ, Yan H. Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study. Exp Ther Med. 2015 Jan;9(1):137-142. doi: 10.3892/etm.2014.2068. Epub 2014 Nov 12. PMID: 25452789; PMCID: PMC4247322.
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Exp Ther Med. 2015 Jan;9(1):137-142. doi: 10.3892/etm.2014.2068. Epub 2014 Nov 12.

Correlation between red blood cell transfusion volume and mortality in patients with massive blood transfusion: A large multicenter retrospective study.

Experimental and therapeutic medicine

Jiang-Cun Yang, Yang Sun, Cui-Xiang Xu, Qian-Li Dang, Ling Li, Yong-Gang Xu, Yao-Jun Song, Hong Yan

Affiliations

  1. Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
  2. Shaanxi Provincial Center for Clinical Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
  3. Department of Dermatology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
  4. Department of Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
  5. Department of Urology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.
  6. Department of Epidemiology and Health Statistics, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

PMID: 25452789 PMCID: PMC4247322 DOI: 10.3892/etm.2014.2068

Abstract

This study aimed to explore the correlation between red blood cell (RBC) transfusion volume and patient mortality in massive blood transfusion. A multicenter retrospective study was carried out on 1,601 surgical inpatients who received massive blood transfusion in 20 large comprehensive hospitals in China. According to RBC transfusion volume and duration, the patients were divided into groups as follows: 0-4, 5-9, 10-14, 15-19, 20-24, 25-29, 30-39 and ≥40 units within 24 or 72 h. Mortality in patients with different RBC transfusion volumes was analyzed. It was found that patient mortality increased with the increase in the volume of RBC transfusion when the total RBC transfusion volume was ≥10 units within 24 or 72 h. Survival analysis revealed significant differences in mortality according to the RBC transfusion volume (χ

Keywords: massive blood transfusion; mortality; multicenter; red blood cell; retrospective analysis

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