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Platzer B, Elpek KG, Cremasco V, et al. IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses. Cell Rep. 2015;10(9):1487-1495doi: 10.1016/j.celrep.2015.02.015.
Platzer, B., Elpek, K. G., Cremasco, V., Baker, K., Stout, M. M., Schultz, C., Dehlink, E., Shade, K. C., Anthony, R. M., Blumberg, R. S., Turley, S. J., & Fiebiger, E. (2015). IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses. Cell reports, 10(9), 1487-1495. https://doi.org/10.1016/j.celrep.2015.02.015
Platzer, Barbara, et al. "IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses." Cell reports vol. 10,9 (2015): 1487-1495. doi: https://doi.org/10.1016/j.celrep.2015.02.015
Platzer B, Elpek KG, Cremasco V, Baker K, Stout MM, Schultz C, Dehlink E, Shade KC, Anthony RM, Blumberg RS, Turley SJ, Fiebiger E. IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses. Cell Rep. 2015 Mar 10;10(9):1487-1495. doi: 10.1016/j.celrep.2015.02.015. Epub 2015 Mar 05. PMID: 25753415; PMCID: PMC4559493.
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Cell Rep. 2015 Mar 10;10(9):1487-1495. doi: 10.1016/j.celrep.2015.02.015. Epub 2015 Mar 05.

IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses.

Cell reports

Barbara Platzer, Kutlu G Elpek, Viviana Cremasco, Kristi Baker, Madeleine M Stout, Cornelia Schultz, Eleonora Dehlink, Kai-Ting C Shade, Robert M Anthony, Richard S Blumberg, Shannon J Turley, Edda Fiebiger

Affiliations

  1. Division of Gastroenterology and Nutrition, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
  2. Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  3. Division of Gastroenterology, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  4. Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.
  5. Division of Gastroenterology and Nutrition, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: [email protected].

PMID: 25753415 PMCID: PMC4559493 DOI: 10.1016/j.celrep.2015.02.015

Abstract

Epidemiologic studies discovered an inverse association between immunoglobulin E (IgE)-mediated allergies and cancer, implying tumor-protective properties of IgE. However, the underlying immunologic mechanisms remain poorly understood. Antigen cross-presentation by dendritic cells (DCs) is of key importance for anti-tumor immunity because it induces the generation of cytotoxic CD8

Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

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