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Li S, Wang L, Zhao S, et al. Preparation of phenyl-functionalized magnetic mesoporous silica microspheres for the fast separation and selective enrichment of phenyl-containing peptides. J Sep Sci. 2015;38(22):3954-3960doi: 10.1002/jssc.201500876.
Li, S., Wang, L., Zhao, S., Lin, J., Zheng, J., & Lin, Z. (2015). Preparation of phenyl-functionalized magnetic mesoporous silica microspheres for the fast separation and selective enrichment of phenyl-containing peptides. Journal of separation science, 38(22), 3954-3960. https://doi.org/10.1002/jssc.201500876
Li, Shihua, et al. "Preparation of phenyl-functionalized magnetic mesoporous silica microspheres for the fast separation and selective enrichment of phenyl-containing peptides." Journal of separation science vol. 38,22 (2015): 3954-3960. doi: https://doi.org/10.1002/jssc.201500876
Li S, Wang L, Zhao S, Lin J, Zheng J, Lin Z. Preparation of phenyl-functionalized magnetic mesoporous silica microspheres for the fast separation and selective enrichment of phenyl-containing peptides. J Sep Sci. 2015 Nov;38(22):3954-3960. doi: 10.1002/jssc.201500876. Epub 2015 Oct 14. PMID: 26377040.
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J Sep Sci. 2015 Nov;38(22):3954-3960. doi: 10.1002/jssc.201500876. Epub 2015 Oct 14.

Preparation of phenyl-functionalized magnetic mesoporous silica microspheres for the fast separation and selective enrichment of phenyl-containing peptides.

Journal of separation science

Shihua Li, Ling Wang, Sen Zhao, Jinjin Lin, Jiangnan Zheng, Zian Lin

Affiliations

  1. Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, China.

PMID: 26377040 DOI: 10.1002/jssc.201500876

Abstract

Peptide enrichment before mass spectrometry analysis is essential for large-scale peptidomic studies, but challenges still remain. Herein, magnetic mesoporous silica microspheres with phenyl group modified interior pore walls were prepared by a facile sol-gel coating strategy, and were successfully applied for selective enrichment of phenyl-containing peptides in complex biological samples. The newly prepared nanomaterials possessed abundant silanol groups in the exterior surface and numerous phenyl groups in the interior pore walls, as well as a large surface area (592.6 m

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords: Magnetic separation; Mesoporous microspheres; Peptides; Sample preparation

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