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Yuan J, Tan T, Geng M, et al. Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis. Front Physiol. 2017;8:1014doi: 10.3389/fphys.2017.01014.
Yuan, J., Tan, T., Geng, M., Tan, G., Chheda, C., & Pandol, S. J. (2017). Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis. Frontiers in physiology, 81014. https://doi.org/10.3389/fphys.2017.01014
Yuan, Jingzhen, et al. "Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis." Frontiers in physiology vol. 8 (2017): 1014. doi: https://doi.org/10.3389/fphys.2017.01014
Yuan J, Tan T, Geng M, Tan G, Chheda C, Pandol SJ. Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis. Front Physiol. 2017 Dec 07;8:1014. doi: 10.3389/fphys.2017.01014. eCollection 2017. PMID: 29270134; PMCID: PMC5725929.
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Front Physiol. 2017 Dec 07;8:1014. doi: 10.3389/fphys.2017.01014. eCollection 2017.

Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis.

Frontiers in physiology

Jingzhen Yuan, Tanya Tan, Meng Geng, Grace Tan, Chintan Chheda, Stephen J Pandol

Affiliations

  1. Cedars-Sinai Medical Center, Los Angeles, CA, United States.
  2. Veterans Affairs Greater Los Angeles Healthcare System, Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
  3. Georgetown University Medical Center, Washington, DC, United States.
  4. Frank Netter H. School of Medicine at Quinnipiac University, Hamden, CT, United States.
  5. Vanderbilt University, Nashville, TN, United States.

PMID: 29270134 PMCID: PMC5725929 DOI: 10.3389/fphys.2017.01014

Abstract

Nuclear factor-kappa B (NF-κB) activation is a key early signal regulating inflammatory and cell death responses in acute pancreatitis. Our previous

Keywords: NF-κB; PKD inhibitors; pancreatitis; protein kinase D

References

  1. Am J Physiol Cell Physiol. 2000 Dec;279(6):C1993-2003 - PubMed
  2. Am J Physiol Cell Physiol. 2014 May 15;306(10 ):C961-71 - PubMed
  3. J Biol Chem. 2006 Feb 10;281(6):3370-81 - PubMed
  4. Gastroenterology. 2002 Feb;122(2):448-57 - PubMed
  5. Am J Physiol Gastrointest Liver Physiol. 2011 Jan;300(1):G120-9 - PubMed
  6. Biochim Biophys Acta. 2007 Apr;1773(4):483-501 - PubMed
  7. Am J Physiol Gastrointest Liver Physiol. 2004 Sep;287(3):G582-91 - PubMed
  8. Acta Haematol. 2004;111(1-2):56-66 - PubMed
  9. Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G68-79 - PubMed
  10. J Gastroenterol. 2016 Jul;51(7):651-9 - PubMed
  11. Biochem Biophys Res Commun. 2002 Mar 1;291(3):444-52 - PubMed
  12. Exp Cell Res. 2009 Jul 1;315(11):1975-89 - PubMed
  13. J Biol Chem. 2009 Jan 23;284(4):2459-71 - PubMed
  14. Gastroenterology. 1997 Dec;113(6):1966-75 - PubMed
  15. Gastroenterology. 1999 Sep;117(3):706-16 - PubMed
  16. Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1197-208 - PubMed
  17. J Leukoc Biol. 1999 Mar;65(3):291-8 - PubMed
  18. Oncogene. 2002 Mar 28;21(14):2154-60 - PubMed
  19. Eur J Immunol. 1997 May;27(5):1091-7 - PubMed
  20. J Biol Chem. 2008 May 9;283(19):12877-87 - PubMed
  21. J Biol Chem. 2008 Feb 1;283(5):2614-21 - PubMed
  22. Gastroenterology. 1999 Mar;116(3):694-701 - PubMed
  23. Mol Cancer Ther. 2010 May;9(5):1136-46 - PubMed
  24. J Cell Biochem. 2008 Feb 1;103(2):648-62 - PubMed
  25. Mol Pharmacol. 2004 Oct;66(4):870-9 - PubMed
  26. Mol Cell Biol. 2006 Feb;26(4):1569-77 - PubMed
  27. J Biol Chem. 2008 Nov 28;283(48):33516-26 - PubMed
  28. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1190-201 - PubMed
  29. Curr Opin Gastroenterol. 2006 Sep;22(5):481-6 - PubMed
  30. J Cell Biol. 2007 Jul 2;178(1):15-22 - PubMed
  31. Gut. 2005 Dec;54(12):1759-67 - PubMed
  32. Gut. 1999 Feb;44(2):253-8 - PubMed
  33. J Biol Chem. 2005 Apr 8;280(14):13205-8 - PubMed
  34. Am J Physiol Gastrointest Liver Physiol. 2005 Jun;288(6):G1259-65 - PubMed
  35. J Clin Invest. 2001 Jan;107(1):7-11 - PubMed
  36. Oncogene. 2003 Dec 4;22(55):8939-47 - PubMed
  37. J Pathol. 2000 Feb;190(2):117-25 - PubMed
  38. Gut. 1990 Oct;31(10):1138-43 - PubMed
  39. Am J Physiol Cell Physiol. 2007 Feb;292(2):C767-77 - PubMed
  40. J Immunol. 2005 Sep 15;175(6):3463-8 - PubMed
  41. Front Physiol. 2012 Mar 27;3:60 - PubMed
  42. J Biol Chem. 1998 Aug 28;273(35):22201-8 - PubMed
  43. Pancreatology. 2007;7(2-3):105-14 - PubMed
  44. J Biol Chem. 2007 May 18;282(20):14777-87 - PubMed
  45. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3059-63 - PubMed
  46. Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G85-95 - PubMed
  47. J Biol Chem. 2003 Feb 14;278(7):4882-91 - PubMed
  48. Physiology (Bethesda). 2011 Feb;26(1):23-33 - PubMed
  49. Am J Physiol. 1998 Dec;275(6 Pt 1):G1402-14 - PubMed
  50. Gastroenterology. 2002 Apr;122(4):974-84 - PubMed
  51. Mol Cell Biol. 2004 Apr;24(7):2614-26 - PubMed
  52. J Biol Chem. 1995 May 19;270(20):11703-6 - PubMed

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