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Liu C, Zhou B, Geng Y, et al. A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K. Chem Sci. 2018;10(1):218-226doi: 10.1039/c8sc03813a.
Liu, C., Zhou, B., Geng, Y., Yan Tam, D., Feng, R., Miao, H., Xu, N., Shi, X., You, Y., Hong, Y., Tang, B. Z., Kwan Lo, P., Kuryavyi, V., & Zhu, G. (2019). A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K. Chemical science, 10(1), 218-226. https://doi.org/10.1039/c8sc03813a
Liu, Changdong, et al. "A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K." Chemical science vol. 10,1 (2019): 218-226. doi: https://doi.org/10.1039/c8sc03813a
Liu C, Zhou B, Geng Y, Yan Tam D, Feng R, Miao H, Xu N, Shi X, You Y, Hong Y, Tang BZ, Kwan Lo P, Kuryavyi V, Zhu G. A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K. Chem Sci. 2018 Oct 04;10(1):218-226. doi: 10.1039/c8sc03813a. eCollection 2019 Jan 07. PMID: 30713633; PMCID: PMC6330691.
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Chem Sci. 2018 Oct 04;10(1):218-226. doi: 10.1039/c8sc03813a. eCollection 2019 Jan 07.

A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K.

Chemical science

Changdong Liu, Bo Zhou, Yanyan Geng, Dick Yan Tam, Rui Feng, Haitao Miao, Naining Xu, Xiao Shi, Yingying You, Yuning Hong, Ben Zhong Tang, Pik Kwan Lo, Vitaly Kuryavyi, Guang Zhu

Affiliations

  1. Division of Life Science , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China . Email: [email protected].
  2. Institute for Advanced Study , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China.
  3. Department of Biology and Chemistry , City University of Hong Kong , 83 Tat Chee Avenue , Kowloon Tong , Hong Kong SAR , China.
  4. Department of Chemistry , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China.
  5. Structural Biology Program , Memorial Sloan-Kettering Cancer Center , New York , NY , USA . Email: [email protected].
  6. Institute for Advanced Study and State Key Laboratory of Molecular Neuroscience , The Hong Kong University of Science and Technology , Clear Water Bay , Kowloon , Hong Kong SAR , China.

PMID: 30713633 PMCID: PMC6330691 DOI: 10.1039/c8sc03813a

Abstract

Guanine tracts of human telomeric DNA sequences are known to fold into eight different four-stranded structures that vary by the conformation of guanine nucleotides arranged in the stack of G-tetrads in their core and by different kinds and orders of connecting loops, called G-quadruplexes. Here, we present a novel G-quadruplex structure formed in K

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