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Humphreys IR, Pei J, Baek M, et al. Computed structures of core eukaryotic protein complexes. Science. 2021;374(6573):eabm4805doi: 10.1126/science.abm4805.
Humphreys, I. R., Pei, J., Baek, M., Krishnakumar, A., Anishchenko, I., Ovchinnikov, S., Zhang, J., Ness, T. J., Banjade, S., Bagde, S. R., Stancheva, V. G., Li, X. H., Liu, K., Zheng, Z., Barrero, D. J., Roy, U., Kuper, J., Fernández, I. S., Szakal, B., Branzei, D., Rizo, J., Kisker, C., Greene, E. C., Biggins, S., Keeney, S., Miller, E. A., Fromme, J. C., Hendrickson, T. L., Cong, Q., & Baker, D. (2021). Computed structures of core eukaryotic protein complexes. Science (New York, N.Y.), 374(6573), eabm4805. https://doi.org/10.1126/science.abm4805
Humphreys, Ian R, et al. "Computed structures of core eukaryotic protein complexes." Science (New York, N.Y.) vol. 374,6573 (2021): eabm4805. doi: https://doi.org/10.1126/science.abm4805
Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D. Computed structures of core eukaryotic protein complexes. Science. 2021 Dec 10;374(6573):eabm4805. doi: 10.1126/science.abm4805. Epub 2021 Dec 10. PMID: 34762488.
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Science. 2021 Dec 10;374(6573):eabm4805. doi: 10.1126/science.abm4805. Epub 2021 Dec 10.

Computed structures of core eukaryotic protein complexes.

Science (New York, N.Y.)

Ian R Humphreys, Jimin Pei, Minkyung Baek, Aditya Krishnakumar, Ivan Anishchenko, Sergey Ovchinnikov, Jing Zhang, Travis J Ness, Sudeep Banjade, Saket R Bagde, Viktoriya G Stancheva, Xiao-Han Li, Kaixian Liu, Zhi Zheng, Daniel J Barrero, Upasana Roy, Jochen Kuper, Israel S Fernández, Barnabas Szakal, Dana Branzei, Josep Rizo, Caroline Kisker, Eric C Greene, Sue Biggins, Scott Keeney, Elizabeth A Miller, J Christopher Fromme, Tamara L Hendrickson, Qian Cong, David Baker

Affiliations

  1. Department of Biochemistry, University of Washington, Seattle, WA, USA.
  2. Institute for Protein Design, University of Washington, Seattle, WA, USA.
  3. Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  4. Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  5. Faculty of Arts and Sciences, Division of Science, Harvard University, Cambridge, MA, USA.
  6. John Harvard Distinguished Science Fellowship Program, Harvard University, Cambridge, MA, USA.
  7. Department of Chemistry, Wayne State University, Detroit, MI, USA.
  8. Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA.
  9. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
  10. Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  11. Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY, USA.
  12. Howard Hughes Medical Institute, Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  13. Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
  14. Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
  15. Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA.
  16. IFOM, the FIRC Institute of Molecular Oncology, Via Adamello 16, 20139, Milan, Italy.
  17. Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (IGM-CNR), Via Abbiategrasso 207, 27100, Pavia, Italy.
  18. Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  19. Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  20. Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  21. Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.

PMID: 34762488 DOI: 10.1126/science.abm4805

Abstract

[Figure: see text].

Publication Types

Grant support