Display options
Cite
Ravichandran G, Lakshmanan DK, Arunachalam A, et al. Food obesogens as emerging metabolic disruptors; A toxicological insight. J Steroid Biochem Mol Biol. 2021;217:106042doi: 10.1016/j.jsbmb.2021.106042.
Ravichandran, G., Lakshmanan, D. K., Arunachalam, A., & Thilagar, S. (2021). Food obesogens as emerging metabolic disruptors; A toxicological insight. The Journal of steroid biochemistry and molecular biology, 217106042. https://doi.org/10.1016/j.jsbmb.2021.106042
Ravichandran, Guna, et al. "Food obesogens as emerging metabolic disruptors; A toxicological insight." The Journal of steroid biochemistry and molecular biology vol. 217 (2021): 106042. doi: https://doi.org/10.1016/j.jsbmb.2021.106042
Ravichandran G, Lakshmanan DK, Arunachalam A, Thilagar S. Food obesogens as emerging metabolic disruptors; A toxicological insight. J Steroid Biochem Mol Biol. 2021 Dec 07;217:106042. doi: 10.1016/j.jsbmb.2021.106042. Epub 2021 Dec 07. PMID: 34890825.
Copy Download .nbib Format: NLM
Share it on

J Steroid Biochem Mol Biol. 2021 Dec 07;217:106042. doi: 10.1016/j.jsbmb.2021.106042. Epub 2021 Dec 07.

Food obesogens as emerging metabolic disruptors; A toxicological insight.

The Journal of steroid biochemistry and molecular biology

Guna Ravichandran, Dinesh Kumar Lakshmanan, Abirami Arunachalam, Sivasudha Thilagar

Affiliations

  1. Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, India.
  2. Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, India; Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam, Erode, India.
  3. Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, India. Electronic address: [email protected].

PMID: 34890825 DOI: 10.1016/j.jsbmb.2021.106042

Abstract

Human food is composed of loads of chemicals derived naturally as well as unintentionally through environmental sources. Food additives added purposefully, play an important role in the palatability of foods. Most additives are synthetic whose essentiality in food processing is well-known however their health risks are not overlooked. The palatability of food should not only stimulate our eating desire alone but, also assure sufficient quality and safety. Application of food additives varies from region to region due to cultural or ethnic differences and the local food availability. There are about more than ten thousand chemicals allowed in food whereas due to weak enforcement, it becomes onerous for regulatory bodies identifying chemicals that are inadequately or not tested at all for safety. The hiking population and urbanization in many industrialized and developing countries resulted in life-style changes including culinary and eating choices. Particularly, the modern way of this globalised life demands ready-to-cook or ready-made foods, snacks, sweets, soft drinks, desserts, confectionery and so on. These sorts of food would be most uninteresting unless processed with additives. This puts food industries under demand to robustly supply foods that are either partially, fully or ultra-processed using plenty of additives. Recent research warns consuming food additives may result in serious health risks, not only for children but also for adults. Growing body of studies on food additives in various experimental animals, cell cultures, and human population suggest elevation of number of obesity and diabetes risk factors i.e. adiposity, dyslipidemia, weight gain, hyperglycaemia, insulin resistance, glucose intolerance, energy imbalance, hormonal intervention etc. Hence, it is important to identify and explore food obesogens or obesogenic food additives posing potential impact. Based on the recent toxicological findings, the review aspires to establish the association between exposure of food obesogen and metabolic disruption which may help filling knowledge gaps and distributing more knowledge, awareness and effective measures to implement treatment and preventive strategies for metabolic syndrome.

Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords: Diabetes; Food additives; Food processing; Insulin resistance; Metabolic disruption; Obesity; Obesogen

Publication Types