Display options
Share it on

Front Endocrinol (Lausanne). 2021 Oct 28;12:735132. doi: 10.3389/fendo.2021.735132. eCollection 2021.

Case Report: Successful Outcome for Refractory Diabetic Peripheral Neuropathy in Patients With Ultrasound-Guided Injection Treatment.

Frontiers in endocrinology

Hua Qiong Hu, Hailun Huang, Jing Huang, Ji Cui Leng, Mi Li, Chao Tang, Yan Li, Shan Wu

Affiliations

  1. Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.

PMID: 34777245 PMCID: PMC8581352 DOI: 10.3389/fendo.2021.735132

Abstract

Diabetic peripheral neuropathy is the most prevalent chronic complication of diabetes and is based on sensory and autonomic nerve symptoms. Generally, intensive glucose control and nerve nourishment are the main treatments. However, it is difficult to improve the symptoms for some patients; such cases are defined as refractory diabetic peripheral neuropathy (RDPN). In this paper, we present five patients treated with saline and mecobalamin by ultrasound-guided injection. The Visual Analog Scale and Toronto Clinical Scoring System were used to evaluate the symptoms, and the neuro-ultrasound scoring system and electrophysiological severity scale were evaluated by ultrasound and electrophysiological examination. In brief, ultrasound-guided hydrodissection may be a safe way to treat RDPN.

Copyright © 2021 Hu, Huang, Huang, Leng, Li, Tang, Li and Wu.

Keywords: electrophysiological; hydrodissection; peripheral nerve compression; refractory diabetic peripheral neuropathy; the scoring system of ultrasound

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. Acta Biomater. 2017 Apr 15;53:250-259 - PubMed
  2. Can J Urol. 2008 Apr;15(2):4000-3 - PubMed
  3. J Pain Res. 2020 Aug 04;13:1957-1968 - PubMed
  4. J Ultrasound Med. 2008 Oct;27(10):1485-90 - PubMed
  5. Orthopedics. 2015 Nov;38(11):e1046-50 - PubMed
  6. Clin Ther. 1987;9(2):183-92 - PubMed
  7. Hand (N Y). 2019 May;14(3):413-421 - PubMed
  8. Medicine (Baltimore). 2014 Dec;93(29):e350 - PubMed
  9. Aust N Z J Surg. 1997 Sep;67(9):643-4 - PubMed
  10. J Diabetes Res. 2014;2014:927069 - PubMed
  11. Clin Rheumatol. 2011 Jun;30(6):805-13 - PubMed
  12. Curr Sports Med Rep. 2016 Jan-Feb;15(1):20-2 - PubMed
  13. Scand J Plast Reconstr Surg. 1976;10(1):3-8 - PubMed
  14. Muscle Nerve. 2019 Feb;59(2):174-180 - PubMed

Publication Types