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Ruparelia AA, McKaige EA, Williams C, et al. Metformin rescues muscle function in BAG3 myofibrillar myopathy models. Autophagy. 2020;17(9):2494-2510doi: 10.1080/15548627.2020.1833500.
Ruparelia, A. A., McKaige, E. A., Williams, C., Schulze, K. E., Fuchs, M., Oorschot, V., Lacene, E., Meregalli, M., Lee, C., Serrano, R. J., Baxter, E. C., Monro, K., Torrente, Y., Ramm, G., Stojkovic, T., Lavoie, J. N., & Bryson-Richardson, R. J. (2021). Metformin rescues muscle function in BAG3 myofibrillar myopathy models. Autophagy, 17(9), 2494-2510. https://doi.org/10.1080/15548627.2020.1833500
Ruparelia, Avnika A, et al. "Metformin rescues muscle function in BAG3 myofibrillar myopathy models." Autophagy vol. 17,9 (2021): 2494-2510. doi: https://doi.org/10.1080/15548627.2020.1833500
Ruparelia AA, McKaige EA, Williams C, Schulze KE, Fuchs M, Oorschot V, Lacene E, Meregalli M, Lee C, Serrano RJ, Baxter EC, Monro K, Torrente Y, Ramm G, Stojkovic T, Lavoie JN, Bryson-Richardson RJ. Metformin rescues muscle function in BAG3 myofibrillar myopathy models. Autophagy. 2021 Sep;17(9):2494-2510. doi: 10.1080/15548627.2020.1833500. Epub 2020 Oct 19. PMID: 33030392; PMCID: PMC8496720.
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Autophagy. 2021 Sep;17(9):2494-2510. doi: 10.1080/15548627.2020.1833500. Epub 2020 Oct 19.

Metformin rescues muscle function in BAG3 myofibrillar myopathy models.

Autophagy

Avnika A Ruparelia, Emily A McKaige, Caitlin Williams, Keith E Schulze, Margit Fuchs, Viola Oorschot, Emmanuelle Lacene, Mirella Meregalli, Clara Lee, Rita J Serrano, Emily C Baxter, Keyne Monro, Yvan Torrente, Georg Ramm, Tanya Stojkovic, Josée N Lavoie, Robert J Bryson-Richardson

Affiliations

  1. School of Biological Sciences, Monash University, Melbourne, Australia.
  2. Monash Micro Imaging, Monash University, Melbourne, Australia.
  3. Centre de Recherche Sur le Cancer de l'Université Laval, Ville de Québec, Canada.
  4. Oncologie, Centre de Recherche du Centre Hospitalier Universitaire (CHU) de Québec-Université Laval, Ville de Québec, Canada.
  5. Monash Ramaciotti Centre for Structural Cryo-Electron Microscopy, Monash University, Melbourne, Australia.
  6. Institut de Myologie, Laboratoire de Pathologie Risler, APHP, Centre de Référence de Pathologie Neuromusculaire Nord/Est/Ile-de-France, Paris, France.
  7. Stem Cell Laboratory, Department of Pathophysiology and Transplantation, Università Degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Centro Dino Ferrari, Milan, Italy.
  8. Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, Australia.
  9. Institut de Myologie, Centre de Référence des Maladies Neuromusculaires, Hôpital Pitié-Salpétrière, Assistance-Publique Hôpitaux de Paris, Sorbonne Université, Paris, France.
  10. Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Université Laval, Ville de Québec, Canada.

PMID: 33030392 PMCID: PMC8496720 DOI: 10.1080/15548627.2020.1833500

Abstract

Dominant

Keywords: Autophagy; BAG3; metformin; muscle; myofibrillar myopathy; zebrafish

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