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Showing 13 to 24 of 1123 entries
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Natural regulatory anticoagulants proteins among Sudanese patients with dengue virus infection.

International journal of health sciences

Bashir BA, Saeed OKA.
PMID: 28539856
Int J Health Sci (Qassim). 2017 Apr-Jun;11(2):3-8.

THE COAGULATION SYSTEM: Abnormalities in natural physiologic anticoagulants are observed in dengue infection. Laboratory values such as protein C (PC), protein S (PS), and antithrombin (AT) indicate this problem on the coagulation system in dengue. Recently, an interrelationship between...

Establishing the heparin therapeutic range using aPTT and anti-Xa measurements for monitoring unfractionated heparin therapy.

Blood research

Byun JH, Jang IS, Kim JW, Koh EH.
PMID: 27722127
Blood Res. 2016 Sep;51(3):171-174. doi: 10.5045/br.2016.51.3.171. Epub 2016 Sep 23.

BACKGROUND: Unfractionated heparin (UFH) has unstable pharmacokinetics and requires close monitoring. The activated partial thromboplastin time (aPTT) test has been used to monitor UFH therapy for decades in Korea, but its results can be affected by numerous variables. We...

Pharmacokinetic and Pharmacodynamic Interaction Between Tolvaptan and Warfarin in Healthy Subjects.

Clinical pharmacology in drug development

Shoaf SE, Mallikaarjun S.
PMID: 27121221
Clin Pharmacol Drug Dev. 2012 Apr;1(2):67-75. doi: 10.1177/2160763X12439702.

PURPOSE: Tolvaptan, a nonpeptide V2 receptor antagonist approved in Japan and in the United States, is likely to be co-administered with warfarin in patients with heart failure (HF). Therefore, the effect of tolvaptan on warfarin pharmacokinetics, pharmacodynamics, and protein...

Clinical significance of coagulation factors in operable colorectal cancer.

Oncology letters

Lee S, Huh SJ, Oh SY, Koh MS, Kim SH, Lee JH, Han JY, Choi HJ, Kim SJ, Kim HJ.
PMID: 28599468
Oncol Lett. 2017 Jun;13(6):4669-4674. doi: 10.3892/ol.2017.6058. Epub 2017 Apr 20.

Abnormal hemostasis in cancer patients has prev iously been studied. The primary objective of the present study was to evaluate the association between preoperative hemostasis markers and clinicopathological parameters, and to identify a hemostasis marker affecting survival in patients...

Hemodialysis for removal of dabigatran in a patient with gastric hemorrhage.

Acute medicine & surgery

Kashiura M, Fujita H, Sugiyama K, Akashi A, Hamabe Y.
PMID: 29123765
Acute Med Surg. 2015 Jun 30;3(2):132-134. doi: 10.1002/ams2.123. eCollection 2016 Apr.

CASE: An 82-year-old man taking dabigatran was admitted with syncope. Computed tomography showed extravasation from the stomach. Laboratory data revealed renal insufficiency and prolonged activated partial thromboplastin time. The gastric endoscopy showed a gastric ulcer with an exposed vessel....

What should be the laboratory approach against isolated prolongation of a activated partial thromboplastin time?.

Journal of clinical laboratory analysis

Falay M, Senes M, Yücel D, Turhan T, Dagdaş S, Pekin M, Nazaroglu NK, Özet G.
PMID: 29484705
J Clin Lab Anal. 2018 Jul;32(6):e22415. doi: 10.1002/jcla.22415. Epub 2018 Feb 27.

BACKGROUND: This study is a retrospective evaluation of patients who were subject to mixing study in our laboratory due to prolonged APTT. The preliminary diagnoses, clinical manifestations, and results of additional ordered tests were reviewed. The study aims to...

Spontaneous mesenteric hematoma of the sigmoid colon associated with rivaroxaban: A case report.

International journal of surgery case reports

Hirano K, Bando T, Osawa S, Shimizu T, Okumura T, Fujii T.
PMID: 29475168
Int J Surg Case Rep. 2018;44:33-37. doi: 10.1016/j.ijscr.2018.02.008. Epub 2018 Feb 10.

INTRODUCTION: Mesenteric hematoma is a rare condition caused by bleeding localized in the mesenteric vascular tree. This is a first report of spontaneous mesenteric hematoma caused by rivaroxaban.PRESENTATION OF CASE: The patient was a 71-year-old man who had taken...

Acquired Von Willebrand's Syndrome in Systemic Lupus Erythematosus.

Case reports in hematology

Taveras Alam S, Alexis K, Sridharan A, Strakhan M, Elrafei T, Gralla RJ, Reed LJ.
PMID: 25544909
Case Rep Hematol. 2014;2014:208597. doi: 10.1155/2014/208597. Epub 2014 Dec 07.

Acquired von Willebrand syndrome (AVWS) is an uncommon, underdiagnosed, and heterogeneous disease which is increasingly recognized as a cause of bleeding diatheses. Systemic lupus erythematosus (SLE) is an infrequent cause of AVWS. Herein, we report a case of AVWS...

Anticoagulant Activity of Polyphenolic-Polysaccharides Isolated from Melastoma malabathricum L.

Evidence-based complementary and alternative medicine : eCAM

Khoo LT, Abas F, Abdullah JO, Mohd Tohit ER, Hamid M.
PMID: 24987430
Evid Based Complement Alternat Med. 2014;2014:614273. doi: 10.1155/2014/614273. Epub 2014 May 20.

Melastoma malabathricum Linn. is a perennial traditional medicine plants that grows abundantly throughout Asian countries. In this study, M. malabathricum Linn. leaf hot water crude extract with anticoagulant activity was purified through solid phase extraction cartridge and examined for...

The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'.

The journal of trauma and acute care surgery

Pape HC, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, Lichte P, Josten C, Bouillon B, Schmucker U, Stahel P, Giannoudis P, Balogh Z.
PMID: 25494433
J Trauma Acute Care Surg. 2014 Nov;77(5):780-786. doi: 10.1097/TA.0000000000000453.

BACKGROUND: The nomenclature for patients with multiple injuries with high mortality rates is highly variable, and there is a lack of a uniform definition of the term polytrauma. A consensus process was therefore initiated by a panel of international...

Anticoagulation therapy in patients with chronic obstructive pulmonary disease in the acute exacerbation stage.

Experimental and therapeutic medicine

Shi X, Li H.
PMID: 23737881
Exp Ther Med. 2013 May;5(5):1367-1370. doi: 10.3892/etm.2013.1001. Epub 2013 Mar 12.

This aim of this study was to investigate the effects of intervention with low-molecular-weight heparin calcium on the pulmonary function and blood coagulation function of patients with chronic obstructive pulmonary disease (COPD) in the acute exacerbation stage. A total...

Retrospective study of Heparin Administration for Ischemic Stroke when there is an IV-tPA Contraindication.

Surgical neurology international

Hakma Z, Stofko DL, Binning MJ, Liebman K, Veznedaroglu E.
PMID: 24991465
Surg Neurol Int. 2014 May 06;5:62. doi: 10.4103/2152-7806.132032. eCollection 2014.

BACKGROUND: The majority of patients presenting with an ischemic stroke arrive after the 3-4.5 h time window allowed for intravenous tissue plasminogen activator (IV tPA) administration. Most of the literature on heparin use in acute ischemic stroke does not...

Showing 13 to 24 of 1123 entries