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Using Association Rule Mining to Uncover Rarely Occurring Relationships in Two University Online STEM Courses: A Comparative Analysis

STEM and underrepresentation

Bosch N.
GSID: idunJgCbZ3sJ
H Valdiviejas, N Bosch - Grantee Submission, 2020 - ERIC

… The troubling underrepresentation of certain groups of people in STEM majors and careers … to the underrepresentation of certain students in STEM, specifically through online STEM …

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Valdiviejas, H., & Bosch, N. (2020). Using Association Rule Mining to Uncover Rarely Occurring Relationships in Two University Online STEM Courses: A Comparative Analysis. Grantee Submission.
Valdiviejas, Hannah, and Nigel Bosch. "Using Association Rule Mining to Uncover Rarely Occurring Relationships in Two University Online STEM Courses: A Comparative Analysis." Grantee Submission (2020).
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Bone response to zinalco implants.

Journal of applied biomaterials & biomechanics : JABB

Pina MC, Villareal E, Martin S, Leon B, Torres-Villasenor G, Bosch P.
PMID: 20803445
J Appl Biomater Biomech. 2004 May-Aug;2(2):112-9.

The evolution of dog femur bone implanted in vivo with either steel or with a metal alloy (zinalco), was compared at different time-periods inverted exclamation markU9 months. Bone behavior was studied by radiology, scanning electron microscopy (SEM), thermo-gravimetric analysis...

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Pina MC, Villareal E, Martin S, et al. Bone response to zinalco implants. J Appl Biomater Biomech. 2004;2(2):112-9
Pina, M. C., Villareal, E., Martin, S., Leon, B., Torres-Villasenor, G., & Bosch, P. (2004). Bone response to zinalco implants. Journal of applied biomaterials & biomechanics : JABB, 2(2), 112-9.
Pina, Ma C, et al. "Bone response to zinalco implants." Journal of applied biomaterials & biomechanics : JABB vol. 2,2 (2004): 112-9.
Pina MC, Villareal E, Martin S, Leon B, Torres-Villasenor G, Bosch P. Bone response to zinalco implants. J Appl Biomater Biomech. 2004 May-Aug;2(2):112-9. PMID: 20803445.
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Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H...O hydrogen bonds between the components.

Acta crystallographica. Section C, Structural chemistry

Bosch E.
PMID: 27703122
Acta Crystallogr C Struct Chem. 2016 Oct 01;72:748-752. doi: 10.1107/S2053229616014972. Epub 2016 Sep 26.

Weak interactions between organic molecules are important in solid-state structures where the sum of the weaker interactions support the overall three-dimensional crystal structure. The sp-C-H...N hydrogen-bonding interaction is strong enough to promote the deliberate cocrystallization of a series of...

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Bosch E. Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H...O hydrogen bonds between the components. Acta Crystallogr C Struct Chem. 2016;72:748-752doi: 10.1107/S2053229616014972.
Bosch, E. (2016). Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H...O hydrogen bonds between the components. Acta crystallographica. Section C, Structural chemistry, 72748-752. https://doi.org/10.1107/S2053229616014972
Bosch, Eric. "Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H...O hydrogen bonds between the components." Acta crystallographica. Section C, Structural chemistry vol. 72 (2016): 748-752. doi: https://doi.org/10.1107/S2053229616014972
Bosch E. Cocrystals of 1,4-diethynylbenzene with 1,3-diacetylbenzene and benzene-1,4-dicarbaldehyde exhibiting strong nonconventional alkyne-carbonyl C-H...O hydrogen bonds between the components. Acta Crystallogr C Struct Chem. 2016 Oct 01;72:748-752. doi: 10.1107/S2053229616014972. Epub 2016 Sep 26. PMID: 27703122.
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Dynamic acousto-elastic testing applied to a highly dispersive medium and evidence of shell buckling of lipid-coated gas microbubbles.

The Journal of the Acoustical Society of America

Renaud G, Bosch JG, van der Steen AF, de Jong N.
PMID: 26627744
J Acoust Soc Am. 2015 Nov;138(5):2668-77. doi: 10.1121/1.4932587.

Dynamic acousto-elastic testing is applied to a mixture of lipid-coated microbubbles in water. A dynamic change of ambient pressure is produced by a 16 kHz pressure wave having a peak pressure amplitude of 28 kPa. The induced changes of...

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Renaud G, Bosch JG, van der Steen AF, et al. Dynamic acousto-elastic testing applied to a highly dispersive medium and evidence of shell buckling of lipid-coated gas microbubbles. J Acoust Soc Am. 2015;138(5):2668-77doi: 10.1121/1.4932587.
Renaud, G., Bosch, J. G., van der Steen, A. F., & de Jong, N. (2015). Dynamic acousto-elastic testing applied to a highly dispersive medium and evidence of shell buckling of lipid-coated gas microbubbles. The Journal of the Acoustical Society of America, 138(5), 2668-77. https://doi.org/10.1121/1.4932587
Renaud, Guillaume, et al. "Dynamic acousto-elastic testing applied to a highly dispersive medium and evidence of shell buckling of lipid-coated gas microbubbles." The Journal of the Acoustical Society of America vol. 138,5 (2015): 2668-77. doi: https://doi.org/10.1121/1.4932587
Renaud G, Bosch JG, van der Steen AF, de Jong N. Dynamic acousto-elastic testing applied to a highly dispersive medium and evidence of shell buckling of lipid-coated gas microbubbles. J Acoust Soc Am. 2015 Nov;138(5):2668-77. doi: 10.1121/1.4932587. PMID: 26627744.
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Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

Sánchez-Mora C, Richarte V, Garcia-Martínez I, Pagerols M, Corrales M, Bosch R, Vidal R, Viladevall L, Casas M, Cormand B, Ramos-Quiroga JA, Ribasés M.
PMID: 26174753
Am J Med Genet B Neuropsychiatr Genet. 2015 Sep;168(6):480-491. doi: 10.1002/ajmg.b.32340. Epub 2015 Jul 14.

We performed a case-control association study in persistent ADHD considering eight candidate genes (DRD4, DAT1/SLC6A3, COMT, ADRA2A, CES1, CYP2D6, LPHN3, and OPRM1) and found additional evidence for the involvement of the Dup 120bp and VNTR 48bp functional variants within...

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Sánchez-Mora C, Richarte V, Garcia-Martínez I, et al. Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2015;168(6):480-491doi: 10.1002/ajmg.b.32340.
Sánchez-Mora, C., Richarte, V., Garcia-Martínez, I., Pagerols, M., Corrales, M., Bosch, R., Vidal, R., Viladevall, L., Casas, M., Cormand, B., Ramos-Quiroga, J. A., & Ribasés, M. (2015). Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 168(6), 480-491. https://doi.org/10.1002/ajmg.b.32340
Sánchez-Mora, Cristina, et al. "Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder." American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics vol. 168,6 (2015): 480-491. doi: https://doi.org/10.1002/ajmg.b.32340
Sánchez-Mora C, Richarte V, Garcia-Martínez I, Pagerols M, Corrales M, Bosch R, Vidal R, Viladevall L, Casas M, Cormand B, Ramos-Quiroga JA, Ribasés M. Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2015 Sep;168(6):480-491. doi: 10.1002/ajmg.b.32340. Epub 2015 Jul 14. PMID: 26174753.
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Large Group Exposure Treatment: A Feasibility Study of Exposure Combined with Diaphragmatic Breathing in Highly Dental Fearful Individuals.

Frontiers in psychology

Wannemueller A, Jöhren HP, Borgstädt A, Bosch J, Meyers M, Völse M, Scholten S, Margraf J.
PMID: 28111556
Front Psychol. 2017 Jan 06;7:2007. doi: 10.3389/fpsyg.2016.02007. eCollection 2016.

A large-group one session treatment (LG-OST) combining exposure and diaphragmatic breathing as a bodily coping element was carried out to investigate its feasibility and effectiveness in a sample of 43 highly dental fearful individuals treated simultaneously. We assessed subjective...

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Wannemueller A, Jöhren HP, Borgstädt A, et al. Large Group Exposure Treatment: A Feasibility Study of Exposure Combined with Diaphragmatic Breathing in Highly Dental Fearful Individuals. Front Psychol. 2017;7:2007doi: 10.3389/fpsyg.2016.02007.
Wannemueller, A., Jöhren, H. P., Borgstädt, A., Bosch, J., Meyers, M., Völse, M., Scholten, S., & Margraf, J. (2016). Large Group Exposure Treatment: A Feasibility Study of Exposure Combined with Diaphragmatic Breathing in Highly Dental Fearful Individuals. Frontiers in psychology, 72007. https://doi.org/10.3389/fpsyg.2016.02007
Wannemueller, André, et al. "Large Group Exposure Treatment: A Feasibility Study of Exposure Combined with Diaphragmatic Breathing in Highly Dental Fearful Individuals." Frontiers in psychology vol. 7 (2016): 2007. doi: https://doi.org/10.3389/fpsyg.2016.02007
Wannemueller A, Jöhren HP, Borgstädt A, Bosch J, Meyers M, Völse M, Scholten S, Margraf J. Large Group Exposure Treatment: A Feasibility Study of Exposure Combined with Diaphragmatic Breathing in Highly Dental Fearful Individuals. Front Psychol. 2017 Jan 06;7:2007. doi: 10.3389/fpsyg.2016.02007. eCollection 2016. PMID: 28111556; PMCID: PMC5216840.
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Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs.

Molecular therapy. Methods & clinical development

Jaén ML, Vilà L, Elias I, Jimenez V, Rodó J, Maggioni L, Ruiz-de Gopegui R, Garcia M, Muñoz S, Callejas D, Ayuso E, Ferré T, Grifoll I, Andaluz A, Ruberte J, Haurigot V, Bosch F.
PMID: 28626777
Mol Ther Methods Clin Dev. 2017 Apr 05;6:1-7. doi: 10.1016/j.omtm.2017.03.008. eCollection 2017 Sep 15.

Diabetes is a complex metabolic disease that exposes patients to the deleterious effects of hyperglycemia on various organs. Achievement of normoglycemia with exogenous insulin treatment requires the use of high doses of hormone, which increases the risk of life-threatening...

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Jaén ML, Vilà L, Elias I, et al. Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs. Mol Ther Methods Clin Dev. 2017;6:1-7doi: 10.1016/j.omtm.2017.03.008.
Jaén, M. L., Vilà, L., Elias, I., Jimenez, V., Rodó, J., Maggioni, L., Ruiz-de Gopegui, R., Garcia, M., Muñoz, S., Callejas, D., Ayuso, E., Ferré, T., Grifoll, I., Andaluz, A., Ruberte, J., Haurigot, V., & Bosch, F. (2017). Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs. Molecular therapy. Methods & clinical development, 61-7. https://doi.org/10.1016/j.omtm.2017.03.008
Jaén, Maria Luisa, et al. "Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs." Molecular therapy. Methods & clinical development vol. 6 (2017): 1-7. doi: https://doi.org/10.1016/j.omtm.2017.03.008
Jaén ML, Vilà L, Elias I, Jimenez V, Rodó J, Maggioni L, Ruiz-de Gopegui R, Garcia M, Muñoz S, Callejas D, Ayuso E, Ferré T, Grifoll I, Andaluz A, Ruberte J, Haurigot V, Bosch F. Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs. Mol Ther Methods Clin Dev. 2017 Apr 05;6:1-7. doi: 10.1016/j.omtm.2017.03.008. eCollection 2017 Sep 15. PMID: 28626777; PMCID: PMC5466581.
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AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease.

Molecular therapy. Methods & clinical development

Vilà L, Elias I, Roca C, Ribera A, Ferré T, Casellas A, Lage R, Franckhauser S, Bosch F.
PMID: 26015978
Mol Ther Methods Clin Dev. 2014 Oct 01;1:14039. doi: 10.1038/mtm.2014.39. eCollection 2014.

Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disease worldwide, and evidence suggests that it promotes insulin resistance and type 2 diabetes. Caloric restriction (CR) is the only available strategy for NAFLD treatment. The protein deacetylase Sirtuin1...

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Vilà L, Elias I, Roca C, et al. AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease. Mol Ther Methods Clin Dev. 2014;1:14039doi: 10.1038/mtm.2014.39.
Vilà, L., Elias, I., Roca, C., Ribera, A., Ferré, T., Casellas, A., Lage, R., Franckhauser, S., & Bosch, F. (2014). AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease. Molecular therapy. Methods & clinical development, 114039. https://doi.org/10.1038/mtm.2014.39
Vilà, Laia, et al. "AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease." Molecular therapy. Methods & clinical development vol. 1 (2014): 14039. doi: https://doi.org/10.1038/mtm.2014.39
Vilà L, Elias I, Roca C, Ribera A, Ferré T, Casellas A, Lage R, Franckhauser S, Bosch F. AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease. Mol Ther Methods Clin Dev. 2014 Oct 01;1:14039. doi: 10.1038/mtm.2014.39. eCollection 2014. PMID: 26015978; PMCID: PMC4362360.
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Chromatographic Hydrophobicity Index (CHI).

Advances in chromatography

Rosés M, Bosch E, Ràfols C, Fuguet E.
PMID: 26437516
Adv Chromatogr. 2012;50:377-414. doi: 10.1201/b11636-9.

No abstract available.

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Rosés M, Bosch E, Ràfols C, et al. Chromatographic Hydrophobicity Index (CHI). Adv Chromatogr. 2012;50:377-414doi: 10.1201/b11636-9.
Rosés, M., Bosch, E., Ràfols, C., & Fuguet, E. (2012). Chromatographic Hydrophobicity Index (CHI). Advances in chromatography, 50377-414. https://doi.org/10.1201/b11636-9
Rosés, Martí, et al. "Chromatographic Hydrophobicity Index (CHI)." Advances in chromatography vol. 50 (2012): 377-414. doi: https://doi.org/10.1201/b11636-9
Rosés M, Bosch E, Ràfols C, Fuguet E. Chromatographic Hydrophobicity Index (CHI). Adv Chromatogr. 2012;50:377-414. doi: 10.1201/b11636-9. PMID: 26437516.
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Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway.

Diabetes, metabolic syndrome and obesity : targets and therapy

Civantos E, Bosch E, Ramirez E, Zhenyukh O, Egido J, Lorenzo O, Mas S.
PMID: 28652790
Diabetes Metab Syndr Obes. 2017 Jun 07;10:207-222. doi: 10.2147/DMSO.S132537. eCollection 2017.

BACKGROUND: Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used in type 2 diabetes therapy, has demonstrated protective effects in diabetic chronic kidney disease, in part due to its pleiotropic actions. However, its potential direct effects on the kidney are still...

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Civantos E, Bosch E, Ramirez E, et al. Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway. Diabetes Metab Syndr Obes. 2017;10:207-222doi: 10.2147/DMSO.S132537.
Civantos, E., Bosch, E., Ramirez, E., Zhenyukh, O., Egido, J., Lorenzo, O., & Mas, S. (2017). Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway. Diabetes, metabolic syndrome and obesity : targets and therapy, 10207-222. https://doi.org/10.2147/DMSO.S132537
Civantos, Esther, et al. "Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway." Diabetes, metabolic syndrome and obesity : targets and therapy vol. 10 (2017): 207-222. doi: https://doi.org/10.2147/DMSO.S132537
Civantos E, Bosch E, Ramirez E, Zhenyukh O, Egido J, Lorenzo O, Mas S. Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway. Diabetes Metab Syndr Obes. 2017 Jun 07;10:207-222. doi: 10.2147/DMSO.S132537. eCollection 2017. PMID: 28652790; PMCID: PMC5473486.
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Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of .

Oncotarget

Puiggros A, Collado R, Calasanz MJ, Ortega M, Ruiz-Xivillé N, Rivas-Delgado A, Luño E, González T, Navarro B, García-Malo M, Valiente A, Hernández JÁ, Ardanaz MT, Piñan MÁ, Blanco ML, Hernández-Sánchez M, Batlle-López A, Salgado R, Salido M, Ferrer A, Abrisqueta P, Gimeno E, Abella E, Ferrá C, Terol MJ, Ortuño F, Costa D, Moreno C, Carbonell F, Bosch F, Delgado J, Espinet B.
PMID: 28903342
Oncotarget. 2017 Apr 21;8(33):54297-54303. doi: 10.18632/oncotarget.17350. eCollection 2017 Aug 15.

Genomic complexity identified by chromosome banding analysis (CBA) predicts a worse clinical outcome in CLL patients treated either with standard or new treatments. Herein, we analyzed the clinical impact of complex karyotypes (CK) with or without high-risk FISH deletions...

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Puiggros A, Collado R, Calasanz MJ, et al. Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of . Oncotarget. 2017;8(33):54297-54303doi: 10.18632/oncotarget.17350.
Puiggros, A., Collado, R., Calasanz, M. J., Ortega, M., Ruiz-Xivillé, N., Rivas-Delgado, A., Luño, E., González, T., Navarro, B., García-Malo, M., Valiente, A., Hernández, J. �. �., Ardanaz, M. T., Piñan, M. �. �., Blanco, M. L., Hernández-Sánchez, M., Batlle-López, A., Salgado, R., Salido, M., Ferrer, A., Abrisqueta, P., Gimeno, E., Abella, E., Ferrá, C., Terol, M. J., Ortuño, F., Costa, D., Moreno, C., Carbonell, F., Bosch, F., Delgado, J., & Espinet, B. (2017). Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of . Oncotarget, 8(33), 54297-54303. https://doi.org/10.18632/oncotarget.17350
Puiggros, Anna, et al. "Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of ." Oncotarget vol. 8,33 (2017): 54297-54303. doi: https://doi.org/10.18632/oncotarget.17350
Puiggros A, Collado R, Calasanz MJ, Ortega M, Ruiz-Xivillé N, Rivas-Delgado A, Luño E, González T, Navarro B, García-Malo M, Valiente A, Hernández JÁ, Ardanaz MT, Piñan MÁ, Blanco ML, Hernández-Sánchez M, Batlle-López A, Salgado R, Salido M, Ferrer A, Abrisqueta P, Gimeno E, Abella E, Ferrá C, Terol MJ, Ortuño F, Costa D, Moreno C, Carbonell F, Bosch F, Delgado J, Espinet B. Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of . Oncotarget. 2017 Apr 21;8(33):54297-54303. doi: 10.18632/oncotarget.17350. eCollection 2017 Aug 15. PMID: 28903342; PMCID: PMC5589581.
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Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment.

Molecular & cellular oncology

Castel P, Toska E, Zumsteg ZS, Carmona FJ, Elkabets M, Bosch A, Scaltriti M.
PMID: 27308344
Mol Cell Oncol. 2014 Oct 29;1(3):e963447. doi: 10.4161/23723548.2014.963447. eCollection 2014.

The PI3K/AKT/mTOR signaling is important for cell proliferation, survival, and metabolism. Hyperactivation of this pathway is one of the most common signaling abnormalities observed in cancer and a substantial effort has recently been made to develop molecules targeting this...

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Castel P, Toska E, Zumsteg ZS, et al. Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment. Mol Cell Oncol. 2014;1(3):e963447doi: 10.4161/23723548.2014.963447.
Castel, P., Toska, E., Zumsteg, Z. S., Carmona, F. J., Elkabets, M., Bosch, A., & Scaltriti, M. (2014). Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment. Molecular & cellular oncology, 1(3), e963447. https://doi.org/10.4161/23723548.2014.963447
Castel, Pau, et al. "Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment." Molecular & cellular oncology vol. 1,3 (2014): e963447. doi: https://doi.org/10.4161/23723548.2014.963447
Castel P, Toska E, Zumsteg ZS, Carmona FJ, Elkabets M, Bosch A, Scaltriti M. Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment. Mol Cell Oncol. 2014 Oct 29;1(3):e963447. doi: 10.4161/23723548.2014.963447. eCollection 2014. PMID: 27308344; PMCID: PMC4904898.
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