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Fragile X syndrome as a rare disease in China - Therapeutic challenges and opportunities.

Intractable & rare diseases research

Jin X, Chen L.
PMID: 25674387
Intractable Rare Dis Res. 2015 Feb;4(1):39-48. doi: 10.5582/irdr.2014.01037.

Recognized as the most common inherited from of intellectual disability (ID) and the most common known monogenic cause of autism spectrum disorders (ASD), Fragile X syndrome (FXS) is identified as an unmet medical need for the development of personalized...

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Jin X, Chen L. Fragile X syndrome as a rare disease in China - Therapeutic challenges and opportunities. Intractable Rare Dis Res. 2015;4(1):39-48doi: 10.5582/irdr.2014.01037.
Jin, X., & Chen, L. (2015). Fragile X syndrome as a rare disease in China - Therapeutic challenges and opportunities. Intractable & rare diseases research, 4(1), 39-48. https://doi.org/10.5582/irdr.2014.01037
Jin, Xiaowei, and Chen, Li. "Fragile X syndrome as a rare disease in China - Therapeutic challenges and opportunities." Intractable & rare diseases research vol. 4,1 (2015): 39-48. doi: https://doi.org/10.5582/irdr.2014.01037
Jin X, Chen L. Fragile X syndrome as a rare disease in China - Therapeutic challenges and opportunities. Intractable Rare Dis Res. 2015 Feb;4(1):39-48. doi: 10.5582/irdr.2014.01037. PMID: 25674387; PMCID: PMC4322594.
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Corrigendum: Observation of polar vortices in oxide superlattices.

Nature

Yadav AK, Nelson CT, Hsu SL, Hong Z, Clarkson JD, Schlepütz CM, Damodaran AR, Shafer P, Arenholz E, Dedon LR, Chen D, Vishwanath A, Minor AM, Chen LQ, Scott JF, Martin LW, Ramesh R.
PMID: 26934222
Nature. 2016 Jun 02;534(7605):138. doi: 10.1038/nature17420. Epub 2016 Mar 02.

No abstract available.

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Yadav AK, Nelson CT, Hsu SL, et al. Corrigendum: Observation of polar vortices in oxide superlattices. Nature. 2016;534(7605):138doi: 10.1038/nature17420.
Yadav, A. K., Nelson, C. T., Hsu, S. L., Hong, Z., Clarkson, J. D., Schlepütz, C. M., Damodaran, A. R., Shafer, P., Arenholz, E., Dedon, L. R., Chen, D., Vishwanath, A., Minor, A. M., Chen, L. Q., Scott, J. F., Martin, L. W., & Ramesh, R. (2016). Corrigendum: Observation of polar vortices in oxide superlattices. Nature, 534(7605), 138. https://doi.org/10.1038/nature17420
Yadav, A K, et al. "Corrigendum: Observation of polar vortices in oxide superlattices." Nature vol. 534,7605 (2016): 138. doi: https://doi.org/10.1038/nature17420
Yadav AK, Nelson CT, Hsu SL, Hong Z, Clarkson JD, Schlepütz CM, Damodaran AR, Shafer P, Arenholz E, Dedon LR, Chen D, Vishwanath A, Minor AM, Chen LQ, Scott JF, Martin LW, Ramesh R. Corrigendum: Observation of polar vortices in oxide superlattices. Nature. 2016 Jun 02;534(7605):138. doi: 10.1038/nature17420. Epub 2016 Mar 02. PMID: 26934222.
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Intermediates in the cation reactions in solution probed by an in situ surface enhanced Raman scattering method.

Scientific reports

Tan CS, Chen HY, Chen HS, Gwo S, Chen LJ.
PMID: 26333518
Sci Rep. 2015 Sep 03;5:13759. doi: 10.1038/srep13759.

For chemical reactions in liquid state, such as catalysis, understanding of dynamical changes is conducive to practical applications. Solvation of copper salts in aqueous solution has implications for life, the environment, and industry. In an ongoing research, the question...

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Tan CS, Chen HY, Chen HS, et al. Intermediates in the cation reactions in solution probed by an in situ surface enhanced Raman scattering method. Sci Rep. 2015;5:13759doi: 10.1038/srep13759.
Tan, C. S., Chen, H. Y., Chen, H. S., Gwo, S., & Chen, L. J. (2015). Intermediates in the cation reactions in solution probed by an in situ surface enhanced Raman scattering method. Scientific reports, 513759. https://doi.org/10.1038/srep13759
Tan, Chih-Shan, et al. "Intermediates in the cation reactions in solution probed by an in situ surface enhanced Raman scattering method." Scientific reports vol. 5 (2015): 13759. doi: https://doi.org/10.1038/srep13759
Tan CS, Chen HY, Chen HS, Gwo S, Chen LJ. Intermediates in the cation reactions in solution probed by an in situ surface enhanced Raman scattering method. Sci Rep. 2015 Sep 03;5:13759. doi: 10.1038/srep13759. PMID: 26333518; PMCID: PMC4558718.
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Synthesis, structure, ultrafast kinetics, and light-induced dynamics of CuHETPHEN chromophores.

Dalton transactions (Cambridge, England : 2003)

Kohler L, Hayes D, Hong J, Carter TJ, Shelby ML, Fransted KA, Chen LX, Mulfort KL.
PMID: 26924711
Dalton Trans. 2016 Jun 14;45(24):9871-83. doi: 10.1039/c6dt00324a.

Five heteroleptic Cu(i)bis(phenanthroline) chromophores with distinct variation in the steric bulk at the 2,9-phenanthroline position were synthesized using the HETPHEN method, and their ground and excited state properties are described. Analysis of the crystal structures reveals a significant distortion...

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Kohler L, Hayes D, Hong J, et al. Synthesis, structure, ultrafast kinetics, and light-induced dynamics of CuHETPHEN chromophores. Dalton Trans. 2016;45(24):9871-83doi: 10.1039/c6dt00324a.
Kohler, L., Hayes, D., Hong, J., Carter, T. J., Shelby, M. L., Fransted, K. A., Chen, L. X., & Mulfort, K. L. (2016). Synthesis, structure, ultrafast kinetics, and light-induced dynamics of CuHETPHEN chromophores. Dalton transactions (Cambridge, England : 2003), 45(24), 9871-83. https://doi.org/10.1039/c6dt00324a
Kohler, Lars, et al. "Synthesis, structure, ultrafast kinetics, and light-induced dynamics of CuHETPHEN chromophores." Dalton transactions (Cambridge, England : 2003) vol. 45,24 (2016): 9871-83. doi: https://doi.org/10.1039/c6dt00324a
Kohler L, Hayes D, Hong J, Carter TJ, Shelby ML, Fransted KA, Chen LX, Mulfort KL. Synthesis, structure, ultrafast kinetics, and light-induced dynamics of CuHETPHEN chromophores. Dalton Trans. 2016 Jun 14;45(24):9871-83. doi: 10.1039/c6dt00324a. PMID: 26924711.
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Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations.

Journal of physics. Condensed matter : an Institute of Physics journal

Jafri HM, Ma X, Zhao C, Liang D, Huang H, Liu Z, Chen LQ.
PMID: 28925380
J Phys Condens Matter. 2017 Dec 20;29(50):505701. doi: 10.1088/1361-648X/aa8d82.

Time-dependent Ginzburg-Landau equations were solved by the finite difference scheme for a superconducting sample in steady and oscillating magnetic fields for 3D geometry. The dynamic behaviour of penetrating and leaving magnetic vortices in superconductor with the oscillating magnetic field...

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Jafri HM, Ma X, Zhao C, et al. Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations. J Phys Condens Matter. 2017;29(50):505701doi: 10.1088/1361-648X/aa8d82.
Jafri, H. M., Ma, X., Zhao, C., Liang, D., Huang, H., Liu, Z., & Chen, L. Q. (2017). Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations. Journal of physics. Condensed matter : an Institute of Physics journal, 29(50), 505701. https://doi.org/10.1088/1361-648X/aa8d82
Jafri, Hasnain Mehdi, et al. "Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations." Journal of physics. Condensed matter : an Institute of Physics journal vol. 29,50 (2017): 505701. doi: https://doi.org/10.1088/1361-648X/aa8d82
Jafri HM, Ma X, Zhao C, Liang D, Huang H, Liu Z, Chen LQ. Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations. J Phys Condens Matter. 2017 Dec 20;29(50):505701. doi: 10.1088/1361-648X/aa8d82. PMID: 28925380.
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SOCS molecules: the growing players in macrophage polarization and function.

Oncotarget

Zhou D, Chen L, Yang K, Jiang H, Xu W, Luan J.
PMID: 28948005
Oncotarget. 2017 Aug 04;8(36):60710-60722. doi: 10.18632/oncotarget.19940. eCollection 2017 Sep 01.

The concept of macrophage polarization is defined in terms of macrophage phenotypic heterogeneity and functional diversity. Cytokines signals are thought to be required for the polarization of macrophage populations toward different phenotypes at different stages in development, homeostasis and...

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Zhou D, Chen L, Yang K, et al. SOCS molecules: the growing players in macrophage polarization and function. Oncotarget. 2017;8(36):60710-60722doi: 10.18632/oncotarget.19940.
Zhou, D., Chen, L., Yang, K., Jiang, H., Xu, W., & Luan, J. (2017). SOCS molecules: the growing players in macrophage polarization and function. Oncotarget, 8(36), 60710-60722. https://doi.org/10.18632/oncotarget.19940
Zhou, Dexi, et al. "SOCS molecules: the growing players in macrophage polarization and function." Oncotarget vol. 8,36 (2017): 60710-60722. doi: https://doi.org/10.18632/oncotarget.19940
Zhou D, Chen L, Yang K, Jiang H, Xu W, Luan J. SOCS molecules: the growing players in macrophage polarization and function. Oncotarget. 2017 Aug 04;8(36):60710-60722. doi: 10.18632/oncotarget.19940. eCollection 2017 Sep 01. PMID: 28948005; PMCID: PMC5601173.
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[Clinical analysis of thromboembolism associated with lenalidomide-based regimens for multiple myeloma patients].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

Gu Y, Chen LJ, Qu XY, Lu RN, Li J, Lu H, Li JY.
PMID: 27033766
Zhonghua Xue Ye Xue Za Zhi. 2016 Mar;37(3):245-7. doi: 10.3760/cma.j.issn.0253-2727.2016.03.015.

No abstract available.

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Gu Y, Chen LJ, Qu XY, et al. [Clinical analysis of thromboembolism associated with lenalidomide-based regimens for multiple myeloma patients]. Zhonghua Xue Ye Xue Za Zhi. 2016;37(3):245-7doi: 10.3760/cma.j.issn.0253-2727.2016.03.015.
Gu, Y., Chen, L. J., Qu, X. Y., Lu, R. N., Li, J., Lu, H., & Li, J. Y. (2016). [Clinical analysis of thromboembolism associated with lenalidomide-based regimens for multiple myeloma patients]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 37(3), 245-7. https://doi.org/10.3760/cma.j.issn.0253-2727.2016.03.015
Gu, Y, et al. "[Clinical analysis of thromboembolism associated with lenalidomide-based regimens for multiple myeloma patients]." Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi vol. 37,3 (2016): 245-7. doi: https://doi.org/10.3760/cma.j.issn.0253-2727.2016.03.015
Gu Y, Chen LJ, Qu XY, Lu RN, Li J, Lu H, Li JY. [Clinical analysis of thromboembolism associated with lenalidomide-based regimens for multiple myeloma patients]. Zhonghua Xue Ye Xue Za Zhi. 2016 Mar;37(3):245-7. doi: 10.3760/cma.j.issn.0253-2727.2016.03.015. Chinese. PMID: 27033766; PMCID: PMC7342955.
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lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer.

Molecular therapy. Nucleic acids

Li P, Zhang X, Wang L, Du L, Yang Y, Liu T, Li C, Wang C.
PMID: 28918035
Mol Ther Nucleic Acids. 2017 Sep 15;8:356-369. doi: 10.1016/j.omtn.2017.07.007. Epub 2017 Jul 08.

One major reason for the failure of advanced colorectal cancer (CRC) treatment is the occurrence of chemoresistance to fluoropyrimidine (FU)-based chemotherapy. Long non-coding RNA HOTAIR has been considered as a pro-oncogene in multiple cancers. However, the precise functional mechanism...

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Li P, Zhang X, Wang L, et al. lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer. Mol Ther Nucleic Acids. 2017;8:356-369doi: 10.1016/j.omtn.2017.07.007.
Li, P., Zhang, X., Wang, L., Du, L., Yang, Y., Liu, T., Li, C., & Wang, C. (2017). lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer. Molecular therapy. Nucleic acids, 8356-369. https://doi.org/10.1016/j.omtn.2017.07.007
Li, Peilong, et al. "lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer." Molecular therapy. Nucleic acids vol. 8 (2017): 356-369. doi: https://doi.org/10.1016/j.omtn.2017.07.007
Li P, Zhang X, Wang L, Du L, Yang Y, Liu T, Li C, Wang C. lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer. Mol Ther Nucleic Acids. 2017 Sep 15;8:356-369. doi: 10.1016/j.omtn.2017.07.007. Epub 2017 Jul 08. PMID: 28918035; PMCID: PMC5537205.
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Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene.

Oncology letters

Wang X, Chen L, Xiao Z, Wang Y, Liu T, Zhang T, Zhang Y.
PMID: 27698813
Oncol Lett. 2016 Oct;12(4):2457-2462. doi: 10.3892/ol.2016.4966. Epub 2016 Aug 05.

Cluster of differentiation (CD)133 is an important cell surface marker of glioma stem cells (GSCs). The transcription of the CD133 gene is controlled by five alternative promoters (P1, P2, P3, P4 and P5), which are expressed in a tissue-specific...

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Wang X, Chen L, Xiao Z, et al. Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene. Oncol Lett. 2016;12(4):2457-2462doi: 10.3892/ol.2016.4966.
Wang, X., Chen, L., Xiao, Z., Wang, Y., Liu, T., Zhang, T., & Zhang, Y. (2016). Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene. Oncology letters, 12(4), 2457-2462. https://doi.org/10.3892/ol.2016.4966
Wang, Xiaofeng, et al. "Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene." Oncology letters vol. 12,4 (2016): 2457-2462. doi: https://doi.org/10.3892/ol.2016.4966
Wang X, Chen L, Xiao Z, Wang Y, Liu T, Zhang T, Zhang Y. Screening glioma stem cells in U251 cells based on the P1 promoter of the CD133 gene. Oncol Lett. 2016 Oct;12(4):2457-2462. doi: 10.3892/ol.2016.4966. Epub 2016 Aug 05. PMID: 27698813; PMCID: PMC5038209.
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Six new species of the spider genus Spiricoelotes species (Araneae, Agelenidae) from caves in Jiangxi, China.

ZooKeys

Chen L, Zhao Z, Li S.
PMID: 27006612
Zookeys. 2016 Feb 08;(561):1-19. doi: 10.3897/zookeys.561.6965. eCollection 2016.

Six new species of the spider genus Spiricoelotes Wang, 2002 are described, Spiricoelotes anshiensis Chen & Li, sp. n. (♂♀), Spiricoelotes chufengensis Chen & Li, sp. n. (♂♀), Spiricoelotes nansheensis Chen & Li, sp. n. (♂♀), Spiricoelotes taipingensis Chen...

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Chen L, Zhao Z, Li S. Six new species of the spider genus Spiricoelotes species (Araneae, Agelenidae) from caves in Jiangxi, China. Zookeys. 2016;(561):1-19doi: 10.3897/zookeys.561.6965.
Chen, L., Zhao, Z., & Li, S. (2016). Six new species of the spider genus Spiricoelotes species (Araneae, Agelenidae) from caves in Jiangxi, China. ZooKeys, (561), 1-19. https://doi.org/10.3897/zookeys.561.6965
Chen, Lu, et al. "Six new species of the spider genus Spiricoelotes species (Araneae, Agelenidae) from caves in Jiangxi, China." ZooKeys vol. ,561 (2016): 1-19. doi: https://doi.org/10.3897/zookeys.561.6965
Chen L, Zhao Z, Li S. Six new species of the spider genus Spiricoelotes species (Araneae, Agelenidae) from caves in Jiangxi, China. Zookeys. 2016 Feb 08;(561):1-19. doi: 10.3897/zookeys.561.6965. eCollection 2016. PMID: 27006612; PMCID: PMC4768362.
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Demonstration of self-truncated ionization injection for GeV electron beams.

Scientific reports

Mirzaie M, Li S, Zeng M, Hafz NA, Chen M, Li GY, Zhu QJ, Liao H, Sokollik T, Liu F, Ma YY, Chen LM, Sheng ZM, Zhang J.
PMID: 26423136
Sci Rep. 2015 Oct 01;5:14659. doi: 10.1038/srep14659.

Ionization-induced injection mechanism was introduced in 2010 to reduce the laser intensity threshold for controllable electron trapping in laser wakefield accelerators (LWFA). However, usually it generates electron beams with continuous energy spectra. Subsequently, a dual-stage target separating the injection...

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Mirzaie M, Li S, Zeng M, et al. Demonstration of self-truncated ionization injection for GeV electron beams. Sci Rep. 2015;5:14659doi: 10.1038/srep14659.
Mirzaie, M., Li, S., Zeng, M., Hafz, N. A., Chen, M., Li, G. Y., Zhu, Q. J., Liao, H., Sokollik, T., Liu, F., Ma, Y. Y., Chen, L. M., Sheng, Z. M., & Zhang, J. (2015). Demonstration of self-truncated ionization injection for GeV electron beams. Scientific reports, 514659. https://doi.org/10.1038/srep14659
Mirzaie, M, et al. "Demonstration of self-truncated ionization injection for GeV electron beams." Scientific reports vol. 5 (2015): 14659. doi: https://doi.org/10.1038/srep14659
Mirzaie M, Li S, Zeng M, Hafz NA, Chen M, Li GY, Zhu QJ, Liao H, Sokollik T, Liu F, Ma YY, Chen LM, Sheng ZM, Zhang J. Demonstration of self-truncated ionization injection for GeV electron beams. Sci Rep. 2015 Oct 01;5:14659. doi: 10.1038/srep14659. PMID: 26423136; PMCID: PMC4589762.
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N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles.

The Journal of organic chemistry

Zhu LL, Xu XQ, Shi JW, Chen BL, Chen Z.
PMID: 27031001
J Org Chem. 2016 May 06;81(9):3568-75. doi: 10.1021/acs.joc.6b00185. Epub 2016 Apr 08.

A new method was developed to synthesize N(2)-alkyl-substituted 1,2,3-triazole through N-iodosuccinimide (NIS) mediated iodofuctionalization reaction of the alkene group with bi-, mono-, and unsubstituted NH-1,2,3-triazoles. The favored N-1 type hydrogen bond between the iodonium ion intermediate and 1,2,3-triazole was...

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Zhu LL, Xu XQ, Shi JW, et al. N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles. J Org Chem. 2016;81(9):3568-75doi: 10.1021/acs.joc.6b00185.
Zhu, L. L., Xu, X. Q., Shi, J. W., Chen, B. L., & Chen, Z. (2016). N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles. The Journal of organic chemistry, 81(9), 3568-75. https://doi.org/10.1021/acs.joc.6b00185
Zhu, Li-Li, et al. "N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles." The Journal of organic chemistry vol. 81,9 (2016): 3568-75. doi: https://doi.org/10.1021/acs.joc.6b00185
Zhu LL, Xu XQ, Shi JW, Chen BL, Chen Z. N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles. J Org Chem. 2016 May 06;81(9):3568-75. doi: 10.1021/acs.joc.6b00185. Epub 2016 Apr 08. PMID: 27031001.
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Showing 13 to 24 of 7081 entries