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The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable.

Interface focus

Nickerson D, Atalag K, de Bono B, Geiger J, Goble C, Hollmann S, Lonien J, Müller W, Regierer B, Stanford NJ, Golebiewski M, Hunter P.
PMID: 27051515
Interface Focus. 2016 Apr 06;6(2):20150103. doi: 10.1098/rsfs.2015.0103.

Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level through to whole populations of individuals must be integrated, then personalized. This requires interoperability...

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Nickerson D, Atalag K, de Bono B, et al. The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable. Interface Focus. 2016;6(2):20150103doi: 10.1098/rsfs.2015.0103.
Nickerson, D., Atalag, K., de Bono, B., Geiger, J., Goble, C., Hollmann, S., Lonien, J., Müller, W., Regierer, B., Stanford, N. J., Golebiewski, M., & Hunter, P. (2016). The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable. Interface focus, 6(2), 20150103. https://doi.org/10.1098/rsfs.2015.0103
Nickerson, David, et al. "The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable." Interface focus vol. 6,2 (2016): 20150103. doi: https://doi.org/10.1098/rsfs.2015.0103
Nickerson D, Atalag K, de Bono B, Geiger J, Goble C, Hollmann S, Lonien J, Müller W, Regierer B, Stanford NJ, Golebiewski M, Hunter P. The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable. Interface Focus. 2016 Apr 06;6(2):20150103. doi: 10.1098/rsfs.2015.0103. PMID: 27051515; PMCID: PMC4759754.
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Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated vs. non-stimulated Glossina palpalis gambiensis flies.

Frontiers in microbiology

Geiger A, Hamidou Soumana I, Tchicaya B, Rofidal V, Decourcelle M, Santoni V, Hem S.
PMID: 26029185
Front Microbiol. 2015 May 12;6:444. doi: 10.3389/fmicb.2015.00444. eCollection 2015.

The unicellular pathogenic protozoan Trypanosoma brucei gambiense is responsible for the chronic form of sleeping sickness. This vector-borne disease is transmitted to humans by the tsetse fly of the group Glossina palpalis, including the subspecies G. p. gambiensis, in...

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Geiger A, Hamidou Soumana I, Tchicaya B, et al. Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated vs. non-stimulated Glossina palpalis gambiensis flies. Front Microbiol. 2015;6:444doi: 10.3389/fmicb.2015.00444.
Geiger, A., Hamidou Soumana, I., Tchicaya, B., Rofidal, V., Decourcelle, M., Santoni, V., & Hem, S. (2015). Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated vs. non-stimulated Glossina palpalis gambiensis flies. Frontiers in microbiology, 6444. https://doi.org/10.3389/fmicb.2015.00444
Geiger, Anne, et al. "Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated vs. non-stimulated Glossina palpalis gambiensis flies." Frontiers in microbiology vol. 6 (2015): 444. doi: https://doi.org/10.3389/fmicb.2015.00444
Geiger A, Hamidou Soumana I, Tchicaya B, Rofidal V, Decourcelle M, Santoni V, Hem S. Differential expression of midgut proteins in Trypanosoma brucei gambiense-stimulated vs. non-stimulated Glossina palpalis gambiensis flies. Front Microbiol. 2015 May 12;6:444. doi: 10.3389/fmicb.2015.00444. eCollection 2015. PMID: 26029185; PMCID: PMC4428205.
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Mapping search terms to review goals is essential.

BMJ quality & safety

Geiger F, Clayman ML, Scholl I, Liethmann K, Kasper J.
PMID: 26621914
BMJ Qual Saf. 2016 Feb;25(2):130. doi: 10.1136/bmjqs-2015-004994. Epub 2015 Nov 30.

No abstract available.

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Geiger F, Clayman ML, Scholl I, et al. Mapping search terms to review goals is essential. BMJ Qual Saf. 2015;25(2):130doi: 10.1136/bmjqs-2015-004994.
Geiger, F., Clayman, M. L., Scholl, I., Liethmann, K., & Kasper, J. (2016). Mapping search terms to review goals is essential. BMJ quality & safety, 25(2), 130. https://doi.org/10.1136/bmjqs-2015-004994
Geiger, Friedemann, et al. "Mapping search terms to review goals is essential." BMJ quality & safety vol. 25,2 (2016): 130. doi: https://doi.org/10.1136/bmjqs-2015-004994
Geiger F, Clayman ML, Scholl I, Liethmann K, Kasper J. Mapping search terms to review goals is essential. BMJ Qual Saf. 2016 Feb;25(2):130. doi: 10.1136/bmjqs-2015-004994. Epub 2015 Nov 30. PMID: 26621914.
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RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies.

Frontiers in microbiology

Hamidou Soumana I, Klopp C, Ravel S, Nabihoudine I, Tchicaya B, Parrinello H, Abate L, Rialle S, Geiger A.
PMID: 26617594
Front Microbiol. 2015 Nov 13;6:1259. doi: 10.3389/fmicb.2015.01259. eCollection 2015.

Trypanosoma brucei gambiense (Tbg), causing the sleeping sickness chronic form, completes its developmental cycle within the tsetse fly vector Glossina palpalis gambiensis (Gpg) before its transmission to humans. Within the framework of an anti-vector disease control strategy, a global...

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Hamidou Soumana I, Klopp C, Ravel S, et al. RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies. Front Microbiol. 2015;6:1259doi: 10.3389/fmicb.2015.01259.
Hamidou Soumana, I., Klopp, C., Ravel, S., Nabihoudine, I., Tchicaya, B., Parrinello, H., Abate, L., Rialle, S., & Geiger, A. (2015). RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies. Frontiers in microbiology, 61259. https://doi.org/10.3389/fmicb.2015.01259
Hamidou Soumana, Illiassou, et al. "RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies." Frontiers in microbiology vol. 6 (2015): 1259. doi: https://doi.org/10.3389/fmicb.2015.01259
Hamidou Soumana I, Klopp C, Ravel S, Nabihoudine I, Tchicaya B, Parrinello H, Abate L, Rialle S, Geiger A. RNA-seq de novo Assembly Reveals Differential Gene Expression in Glossina palpalis gambiensis Infected with Trypanosoma brucei gambiense vs. Non-Infected and Self-Cured Flies. Front Microbiol. 2015 Nov 13;6:1259. doi: 10.3389/fmicb.2015.01259. eCollection 2015. PMID: 26617594; PMCID: PMC4643127.
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A comparative approach to testing hypotheses for the evolution of sex-biased dispersal in bean beetles.

Ecology and evolution

Downey MH, Searle R, Bellur S, Geiger A, Maitner BS, Ohm JR, Tuda M, Miller TE.
PMID: 26640662
Ecol Evol. 2015 Oct 08;5(21):4819-28. doi: 10.1002/ece3.1753. eCollection 2015 Nov.

Understanding the selective forces that shape dispersal strategies is a fundamental goal of evolutionary ecology and is increasingly important in changing, human-altered environments. Sex-biased dispersal (SBD) is common in dioecious taxa, and understanding variation in the direction and magnitude...

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Downey MH, Searle R, Bellur S, et al. A comparative approach to testing hypotheses for the evolution of sex-biased dispersal in bean beetles. Ecol Evol. 2015;5(21):4819-28doi: 10.1002/ece3.1753.
Downey, M. H., Searle, R., Bellur, S., Geiger, A., Maitner, B. S., Ohm, J. R., Tuda, M., & Miller, T. E. (2015). A comparative approach to testing hypotheses for the evolution of sex-biased dispersal in bean beetles. Ecology and evolution, 5(21), 4819-28. https://doi.org/10.1002/ece3.1753
Downey, Michelle H, et al. "A comparative approach to testing hypotheses for the evolution of sex-biased dispersal in bean beetles." Ecology and evolution vol. 5,21 (2015): 4819-28. doi: https://doi.org/10.1002/ece3.1753
Downey MH, Searle R, Bellur S, Geiger A, Maitner BS, Ohm JR, Tuda M, Miller TE. A comparative approach to testing hypotheses for the evolution of sex-biased dispersal in bean beetles. Ecol Evol. 2015 Oct 08;5(21):4819-28. doi: 10.1002/ece3.1753. eCollection 2015 Nov. PMID: 26640662; PMCID: PMC4662329.
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Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR.

Journal of the American Chemical Society

Geiger Y, Gottlieb HE, Akbey Ü, Oschkinat H, Goobes G.
PMID: 26451953
J Am Chem Soc. 2016 May 04;138(17):5561-7. doi: 10.1021/jacs.5b07809. Epub 2016 Apr 20.

Smart materials are created in nature at interfaces between biomolecules and solid materials. The ability to probe the structure of functional peptides that engineer biogenic materials at this heterogeneous setting can be facilitated tremendously by use of DNP-enhanced solid-state...

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Geiger Y, Gottlieb HE, Akbey Ü, et al. Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR. J Am Chem Soc. 2016;138(17):5561-7doi: 10.1021/jacs.5b07809.
Geiger, Y., Gottlieb, H. E., Akbey, �. �., Oschkinat, H., & Goobes, G. (2016). Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR. Journal of the American Chemical Society, 138(17), 5561-7. https://doi.org/10.1021/jacs.5b07809
Geiger, Yasmin, et al. "Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR." Journal of the American Chemical Society vol. 138,17 (2016): 5561-7. doi: https://doi.org/10.1021/jacs.5b07809
Geiger Y, Gottlieb HE, Akbey Ü, Oschkinat H, Goobes G. Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR. J Am Chem Soc. 2016 May 04;138(17):5561-7. doi: 10.1021/jacs.5b07809. Epub 2016 Apr 20. PMID: 26451953.
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Detection of Cyclo-N.

Angewandte Chemie (International ed. in English)

Bazanov B, Geiger U, Carmieli R, Grinstein D, Welner S, Haas Y.
PMID: 27385080
Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13233-13235. doi: 10.1002/anie.201605400.

Compelling evidence has been found for the formation and direct detection of the cyclopentazole anion (cyclo-N

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Bazanov B, Geiger U, Carmieli R, et al. Detection of Cyclo-N. Angew Chem Int Ed Engl. 2016;55(42):13233-13235doi: 10.1002/anie.201605400.
Bazanov, B., Geiger, U., Carmieli, R., Grinstein, D., Welner, S., & Haas, Y. (2016). Detection of Cyclo-N. Angewandte Chemie (International ed. in English), 55(42), 13233-13235. https://doi.org/10.1002/anie.201605400
Bazanov, Boris, et al. "Detection of Cyclo-N." Angewandte Chemie (International ed. in English) vol. 55,42 (2016): 13233-13235. doi: https://doi.org/10.1002/anie.201605400
Bazanov B, Geiger U, Carmieli R, Grinstein D, Welner S, Haas Y. Detection of Cyclo-N. Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13233-13235. doi: 10.1002/anie.201605400. PMID: 27385080.
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Experimental observation of a generalized Gibbs ensemble.

Science (New York, N.Y.)

Langen T, Erne S, Geiger R, Rauer B, Schweigler T, Kuhnert M, Rohringer W, Mazets IE, Gasenzer T, Schmiedmayer J.
PMID: 25859041
Science. 2015 Apr 10;348(6231):207-11. doi: 10.1126/science.1257026.

The description of the non-equilibrium dynamics of isolated quantum many-body systems within the framework of statistical mechanics is a fundamental open question. Conventional thermodynamical ensembles fail to describe the large class of systems that exhibit nontrivial conserved quantities, and...

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Langen T, Erne S, Geiger R, et al. Experimental observation of a generalized Gibbs ensemble. Science. 2015;348(6231):207-11doi: 10.1126/science.1257026.
Langen, T., Erne, S., Geiger, R., Rauer, B., Schweigler, T., Kuhnert, M., Rohringer, W., Mazets, I. E., Gasenzer, T., & Schmiedmayer, J. (2015). Experimental observation of a generalized Gibbs ensemble. Science (New York, N.Y.), 348(6231), 207-11. https://doi.org/10.1126/science.1257026
Langen, Tim, et al. "Experimental observation of a generalized Gibbs ensemble." Science (New York, N.Y.) vol. 348,6231 (2015): 207-11. doi: https://doi.org/10.1126/science.1257026
Langen T, Erne S, Geiger R, Rauer B, Schweigler T, Kuhnert M, Rohringer W, Mazets IE, Gasenzer T, Schmiedmayer J. Experimental observation of a generalized Gibbs ensemble. Science. 2015 Apr 10;348(6231):207-11. doi: 10.1126/science.1257026. PMID: 25859041.
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Cooling of a One-Dimensional Bose Gas.

Physical review letters

Rauer B, Grišins P, Mazets IE, Schweigler T, Rohringer W, Geiger R, Langen T, Schmiedmayer J.
PMID: 26849577
Phys Rev Lett. 2016 Jan 22;116(3):030402. doi: 10.1103/PhysRevLett.116.030402. Epub 2016 Jan 22.

We experimentally study the dynamics of a degenerate one-dimensional Bose gas that is subject to a continuous outcoupling of atoms. Although standard evaporative cooling is rendered ineffective by the absence of thermalizing collisions in this system, we observe substantial...

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Rauer B, Grišins P, Mazets IE, et al. Cooling of a One-Dimensional Bose Gas. Phys Rev Lett. 2016;116(3):030402doi: 10.1103/PhysRevLett.116.030402.
Rauer, B., Grišins, P., Mazets, I. E., Schweigler, T., Rohringer, W., Geiger, R., Langen, T., & Schmiedmayer, J. (2016). Cooling of a One-Dimensional Bose Gas. Physical review letters, 116(3), 030402. https://doi.org/10.1103/PhysRevLett.116.030402
Rauer, B, et al. "Cooling of a One-Dimensional Bose Gas." Physical review letters vol. 116,3 (2016): 030402. doi: https://doi.org/10.1103/PhysRevLett.116.030402
Rauer B, Grišins P, Mazets IE, Schweigler T, Rohringer W, Geiger R, Langen T, Schmiedmayer J. Cooling of a One-Dimensional Bose Gas. Phys Rev Lett. 2016 Jan 22;116(3):030402. doi: 10.1103/PhysRevLett.116.030402. Epub 2016 Jan 22. PMID: 26849577.
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Lumbar facet joint arthritis is associated with more coronal orientation of the facet joints at the upper lumbar spine.

Radiology research and practice

Jentzsch T, Geiger J, Zimmermann SM, Slankamenac K, Nguyen-Kim TD, Werner CM.
PMID: 24260713
Radiol Res Pract. 2013;2013:693971. doi: 10.1155/2013/693971. Epub 2013 Oct 23.

We retrospectively analyzed CT scans of 620 individuals, who presented to our traumatology department between 2008 and 2010. Facet joint (FJ) arthritis was present in 308 (49.7%) individuals with a mean grade of 1. It was seen in 27%...

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Jentzsch T, Geiger J, Zimmermann SM, et al. Lumbar facet joint arthritis is associated with more coronal orientation of the facet joints at the upper lumbar spine. Radiol Res Pract. 2013;2013:693971doi: 10.1155/2013/693971.
Jentzsch, T., Geiger, J., Zimmermann, S. M., Slankamenac, K., Nguyen-Kim, T. D., & Werner, C. M. (2013). Lumbar facet joint arthritis is associated with more coronal orientation of the facet joints at the upper lumbar spine. Radiology research and practice, 2013693971. https://doi.org/10.1155/2013/693971
Jentzsch, Thorsten, et al. "Lumbar facet joint arthritis is associated with more coronal orientation of the facet joints at the upper lumbar spine." Radiology research and practice vol. 2013 (2013): 693971. doi: https://doi.org/10.1155/2013/693971
Jentzsch T, Geiger J, Zimmermann SM, Slankamenac K, Nguyen-Kim TD, Werner CM. Lumbar facet joint arthritis is associated with more coronal orientation of the facet joints at the upper lumbar spine. Radiol Res Pract. 2013;2013:693971. doi: 10.1155/2013/693971. Epub 2013 Oct 23. PMID: 24260713; PMCID: PMC3821951.
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Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies.

Frontiers in microbiology

Hamidou Soumana I, Tchicaya B, Simo G, Geiger A.
PMID: 25452752
Front Microbiol. 2014 Nov 17;5:620. doi: 10.3389/fmicb.2014.00620. eCollection 2014.

Tsetse flies (Glossina sp.) that transmit trypanosomes causing human (and animal) African trypanosomiasis (HAT and AAT, respectively) harbor symbiotic microorganisms, including the obligate primary symbiont Wigglesworthia glossinidia. A relationship between Wigglesworthia and tsetse fly infection by trypanosomes has been...

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Hamidou Soumana I, Tchicaya B, Simo G, et al. Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies. Front Microbiol. 2014;5:620doi: 10.3389/fmicb.2014.00620.
Hamidou Soumana, I., Tchicaya, B., Simo, G., & Geiger, A. (2014). Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies. Frontiers in microbiology, 5620. https://doi.org/10.3389/fmicb.2014.00620
Hamidou Soumana, Illiassou, et al. "Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies." Frontiers in microbiology vol. 5 (2014): 620. doi: https://doi.org/10.3389/fmicb.2014.00620
Hamidou Soumana I, Tchicaya B, Simo G, Geiger A. Comparative gene expression of Wigglesworthia inhabiting non-infected and Trypanosoma brucei gambiense-infected Glossina palpalis gambiensis flies. Front Microbiol. 2014 Nov 17;5:620. doi: 10.3389/fmicb.2014.00620. eCollection 2014. PMID: 25452752; PMCID: PMC4233935.
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[The year 1989. A turning point for pathology at the University of Leipzig?].

Der Pathologe

Geiler G.
PMID: 11490936
Pathologe. 2001 Jul;22(4):235-40. doi: 10.1007/s002920000450.

No abstract available.

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Geiler G. Das Jahr 1989. Eine Wende auch für die Pathologie an der Universität Leipzig? [The year 1989. A turning point for pathology at the University of Leipzig?]. Pathologe. 2001;22(4):235-40doi: 10.1007/s002920000450.
Geiler, G. (2001). Das Jahr 1989. Eine Wende auch für die Pathologie an der Universität Leipzig? [The year 1989. A turning point for pathology at the University of Leipzig?]. Der Pathologe, 22(4), 235-40. https://doi.org/10.1007/s002920000450
Geiler, G. "Das Jahr 1989. Eine Wende auch für die Pathologie an der Universität Leipzig?" [The year 1989. A turning point for pathology at the University of Leipzig?]. Der Pathologe vol. 22,4 (2001): 235-40. doi: https://doi.org/10.1007/s002920000450
Geiler G. Das Jahr 1989. Eine Wende auch für die Pathologie an der Universität Leipzig? [The year 1989. A turning point for pathology at the University of Leipzig?]. Pathologe. 2001 Jul;22(4):235-40. doi: 10.1007/s002920000450. German. PMID: 11490936.
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Showing 13 to 24 of 626 entries