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Showing 25 to 36 of 3113 entries
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Effect of Comorbidity on Postoperative Survival Outcomes in Patients with Solid Cancers: A 6-Year Multicenter Study in Taiwan.

Journal of Cancer

Chou WC, Chang PH, Lu CH, Liu KH, Hung YS, Hung CY, Liu CT, Yeh KY, Lin YC, Yeh TS.
PMID: 27162545
J Cancer. 2016 Apr 28;7(7):854-61. doi: 10.7150/jca.14777. eCollection 2016.

PURPOSE: Patients with comorbidities are more likely to experience treatment-related toxicities and death. Our aim was to examine the effect of comorbidity on postoperative survival outcomes in patients with solid cancers.METHODS: In total, 37,288 patients who underwent potentially curative...

Quantitative control of CaCO.

The Analyst

Wu C, Sun Z, Liu LS.
PMID: 28612068
Analyst. 2017 Jul 10;142(14):2547-2551. doi: 10.1039/c7an00335h.

The surface crystallization of CaCO

Subcutaneous injection-induced cellulites.

BioMedicine

Cheng KC, Huang PT, Liu CS, Lin WY.
PMID: 28612712
Biomedicine (Taipei). 2017 Jun;7(2):14. doi: 10.1051/bmdcn/2017070206. Epub 2017 Jun 14.

In the hospice ward where patients are in the terminal stages of cancer, it is common practice to give them a subcutaneous injection of pain relievers to reduce their pain and make them more comfortable. Most of these patients...

Cardiovascular Toxicity of Molecular Targeted Therapy in Cancer Patients: A Double-Edged Sword.

Acta Cardiologica Sinica

Liu KL, Chen JS, Chen SC, Chu PH.
PMID: 27122721
Acta Cardiol Sin. 2013 Jul;29(4):295-303.

UNLABELLED: The annual incidence of cancer has increased over the past 20 years, yet the 5-year relative survival rate for cancer has improved with the increasing availability of advanced therapies, including molecular targeted therapy. Cardiovascular toxicity can develop with...

When and How Does Psychological Voice Climate Influence Individual Change Readiness? The Mediating Role of Normative Commitment and the Moderating Role of Work Engagement.

Frontiers in psychology

Lee CH, Wang ML, Liu MS.
PMID: 29062294
Front Psychol. 2017 Oct 09;8:1737. doi: 10.3389/fpsyg.2017.01737. eCollection 2017.

This research explores the linking mechanisms and conditional processes underlying the relationship between psychological voice climate and individual change readiness. In accordance with the social identity theory, we argued that normative commitment would mediate the relationship between psychological voice...

Synthetic approaches to the 2014 new drugs.

Bioorganic & medicinal chemistry

Flick AC, Ding HX, Leverett CA, Kyne RE, Liu KK, Fink SJ, O'Donnell CJ.
PMID: 27020685
Bioorg Med Chem. 2016 May 01;24(9):1937-80. doi: 10.1016/j.bmc.2016.03.004. Epub 2016 Mar 09.

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers...

Measurement of complex refractive index of turbid media by scanning focused refractive index.

Optics letters

Sun TQ, Ye Q, Liu SK, Wang XW, Wang J, Deng ZC, Mei JC, Zhou WY, Zhang CP, Tian JG.
PMID: 27519084
Opt Lett. 2016 Aug 15;41(16):3767-70. doi: 10.1364/OL.41.003767.

We present the application of scanning focused refractive index microscopy in the complex refractive index measurement of turbid media. An extra standard scattering layer is placed in front of the detector to perform scattering transformation on the reflected light....

Chiglitazar Preferentially Regulates Gene Expression via Configuration-Restricted Binding and Phosphorylation Inhibition of PPAR.

PPAR research

Pan DS, Wang W, Liu NS, Yang QJ, Zhang K, Zhu JZ, Shan S, Li ZB, Ning ZQ, Huang L, Lu XP.
PMID: 29056962
PPAR Res. 2017;2017:4313561. doi: 10.1155/2017/4313561. Epub 2017 Sep 19.

Type 2 diabetes mellitus is often treated with insulin-sensitizing drugs called thiazolidinediones (TZD), which improve insulin resistance and glycemic control. Despite their effectiveness in treating diabetes, these drugs provide little protection from eminent cardiovascular disease associated with diabetes. Here...

Applying Thienyl Side Chains and Different π-Bridge to Aromatic Side-Chain Substituted Indacenodithiophene-Based Small Molecule Donors for High-Performance Organic Solar Cells.

ACS applied materials & interfaces

Wang JL, Liu KK, Liu S, Liu F, Wu HB, Cao Y, Russell TP.
PMID: 28535032
ACS Appl Mater Interfaces. 2017 Jun 14;9(23):19998-20009. doi: 10.1021/acsami.7b03771. Epub 2017 Jun 01.

A pair of linear tetrafluorinated small molecular donors, named as ThIDTTh4F and ThIDTSe4F, which are with tetrathienyl-substituted IDT as electron-rich central core, electron-deficient difluorobenzothiadiazole as acceptor units, and donor end-capping groups, but having differences in the π-bridge (thiophene and...

Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.

JCI insight

McKinley ET, Sui Y, Al-Kofahi Y, Millis BA, Tyska MJ, Roland JT, Santamaria-Pang A, Ohland CL, Jobin C, Franklin JL, Lau KS, Gerdes MJ, Coffey RJ.
PMID: 28570279
JCI Insight. 2017 Jun 02;2(11). doi: 10.1172/jci.insight.93487. eCollection 2017 Jun 02.

Intestinal tuft cells are a rare, poorly understood cell type recently shown to be a critical mediator of type 2 immune response to helminth infection. Here, we present advances in segmentation algorithms and analytical tools for multiplex immunofluorescence (MxIF),...

Ligand-Accelerated Direct C-H Arylation of BINOL: A Rapid One-Step Synthesis of Racemic 3,3'-Diaryl BINOLs.

Angewandte Chemie (International ed. in English)

Yang JF, Wang RH, Wang YX, Yao WW, Liu QS, Ye M.
PMID: 27726256
Angew Chem Int Ed Engl. 2016 Nov 02;55(45):14116-14120. doi: 10.1002/anie.201607893. Epub 2016 Oct 11.

An ortho-selective rhodium-catalyzed direct C-H arylation of 1,1'-bi-2-naphthol (BINOL), to deliver the widely used but not easily available 3,3'-diaryl BINOL, has been developed. This highly efficient one-step synthetic approach is the shortest route to date and is greatly facilitated...

Inhibiting system x.

Molecular & cellular oncology

Clemons NJ, Liu DS, Duong CP, Phillips WA.
PMID: 29057306
Mol Cell Oncol. 2017 Jul 05;4(5):e1344757. doi: 10.1080/23723556.2017.1344757. eCollection 2017.

Effective therapeutic strategies to target mutant tumor protein p53 (TP53, best known as p53) cancers remain an unmet medical need. We found that mutant p53 impairs the function of nuclear factor (erythroid-derived 2)-like 2 (NFE2L2, commonly known as NRF2),...

Showing 25 to 36 of 3113 entries