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Showing 1 to 12 of 59 entries
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Avicenna Journal of Medicine: 5-year milestones.

Avicenna journal of medicine

Arabi M, Atassi B, Masrani A, Alahdab F, Al-Moujahed A, Arabi H.
PMID: 26955598
Avicenna J Med. 2016 Jan-Mar;6(1):1-2. doi: 10.4103/2231-0770.173582.

No abstract available.

Systematic reviews with language restrictions and no author contact have lower overall credibility: a methodology study.

Clinical epidemiology

Wang Z, Brito JP, Tsapas A, Griebeler ML, Alahdab F, Murad MH.
PMID: 25878512
Clin Epidemiol. 2015 Mar 31;7:243-7. doi: 10.2147/CLEP.S78879. eCollection 2015.

BACKGROUND: High-quality systematic reviews (SRs) require rigorous approaches to identify, appraise, select, and synthesize research evidence relevant to a specific question. In this study, we evaluated the association between two steps in the conduct of an SR - restricting...

Is extended-field concurrent chemoradiation an option for radiologic negative paraaortic lymph node, locally advanced cervical cancer?.

Cancer management and research

Asiri MA, Tunio MA, Mohamed R, Bayoumi Y, Alhadab A, Saleh RM, AlArifi MS, Alobaid A.
PMID: 25228820
Cancer Manag Res. 2014 Sep 09;6:339-48. doi: 10.2147/CMAR.S68262. eCollection 2014.

BACKGROUND: The aim was to evaluate whether extended-field concurrent chemoradiation (EF-CCRT) leads to results better than those obtained by standard whole-pelvis concurrent chemoradiation (WP-CCRT) in locally advanced cervical cancer with radiologic negative paraaortic lymph nodes (PALNs).PATIENTS AND METHODS: A...

Erratum to: Adjuvant Radioactive iodine 131 ablation in papillary microcarcinoma of thyroid: Saudi Arabian experience.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

AL-Qahtani KH, Al Asiri M, Tunio MA, Aljohani NJ, Bayoumi Y, Fatani H, AlHadab A.
PMID: 26830172
J Otolaryngol Head Neck Surg. 2016 Jan 29;45:6. doi: 10.1186/s40463-016-0122-x.

No abstract available.

Up-regulation of miR-210 induced by a hypoxic microenvironment promotes breast cancer stem cells metastasis, proliferation, and self-renewal by targeting E-cadherin.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Tang T, Yang Z, Zhu Q, Wu Y, Sun K, Alahdal M, Zhang Y, Xing Y, Shen Y, Xia T, Xi T, Pan Y, Jin L.
PMID: 30188754
FASEB J. 2018 Sep 06;fj201801013R. doi: 10.1096/fj.201801013R. Epub 2018 Sep 06.

Breast cancer stem cells (BCSCs), a small subset of breast cancer cells with stem cell-like properties, are essential in tumor formation, metastasis, resistance to anticancer therapies, and cancer recurrence. MicroRNAs (miRNAs) are involved in tumorigenicity by regulating specific oncogenes...

Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study.

JMIR formative research

Zainel AA, Qotba H, Al-Maadeed A, Al-Kohji S, Al Mujalli H, Ali A, Al Mannai L, Aladab A, AlSaadi H, AlKarbi KA, Al-Baghdadi T.
PMID: 33851577
JMIR Form Res. 2021 Apr 27;5(4):e24760. doi: 10.2196/24760.

BACKGROUND: In December 2019, a novel coronavirus called SARS-CoV-2 was identified as the cause of a cluster of pneumonia cases in Wuhan, China. It rapidly spread due to human-to-human transmission, resulting in a global pandemic. Nearly every country, including...

Gastroenterologists Adherence to Tumor Necrosis Factor Antagonist Combination Therapy in Inflammatory Bowel Disease.

Frontiers in medicine

Abdullah I, Alhendi G, Alhadab A, Alasfour H, Shehab M.
PMID: 34660635
Front Med (Lausanne). 2021 Sep 29;8:725512. doi: 10.3389/fmed.2021.725512. eCollection 2021.

No abstract available.

Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study.

JAMA neurology

, Feigin VL, Vos T, Alahdab F, Amit AML, Bärnighausen TW, Beghi E, Beheshti M, Chavan PP, Criqui MH, Desai R, Dhamminda Dharmaratne S, Dorsey ER, Wilder Eagan A, Elgendy IY, Filip I, Giampaoli S, Giussani G, Hafezi-Nejad N, Hole MK, Ikeda T, Owens Johnson C, Kalani R, Khatab K, Khubchandani J, Kim D, Koroshetz WJ, Krishnamoorthy V, Krishnamurthi RV, Liu X, Lo WD, Logroscino G, Mensah GA, Miller TR, Mohammed S, Mokdad AH, Moradi-Lakeh M, Morrison SD, Shivamurthy VKN, Naghavi M, Nichols E, Norrving B, Odell CM, Pupillo E, Radfar A, Roth GA, Shafieesabet A, Sheikh A, Sheikhbahaei S, Shin JI, Singh JA, Steiner TJ, Stovner LJ, Wallin MT, Weiss J, Wu C, Zunt JR, Adelson JD, Murray CJL.
PMID: 33136137
JAMA Neurol. 2021 Feb 01;78(2):165-176. doi: 10.1001/jamaneurol.2020.4152.

IMPORTANCE: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported...

High expression of MAPK-14 promoting the death of chondrocytes is an important signal of osteoarthritis process.

PeerJ

Deng Z, Hu X, Alahdal M, Liu J, Zhao Z, Chen X, Xie J, Duan L, Wang D, Li W.
PMID: 33520453
PeerJ. 2021 Jan 15;9:e10656. doi: 10.7717/peerj.10656. eCollection 2021.

BACKGROUND: Osteoarthritis (OA) is one of the most common degenerative diseases worldwide. Many researchers are studying the pathogenesis of OA, however, it is still unclear.METHODS: Screening and validation of OA relevant hub genes are an important part of exploring...

4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects.

FEBS open bio

Birus R, El-Awaad E, Ballentin L, Alchab F, Aichele D, Ettouati L, Götz C, Le Borgne M, Jose J.
PMID: 34873879
FEBS Open Bio. 2021 Dec 06; doi: 10.1002/2211-5463.13346. Epub 2021 Dec 06.

Highly pleiotropic and constitutively active protein kinase CK2 is a key target in cancer therapy, but only one small-molecule inhibitor has reached clinical trials-CX-4945. In this study, we present the indeno[1,2-b]indole derivative 5-isopropyl-4-methoxy-7-methyl-5,6,7,8-tetrahydroindeno[1,2-b]indole-9,10-dione (5a-2) that decreased the intracellular CK2...

Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model.

Frontiers in immunology

Alahdal M, Huang R, Duan L, Zhiqin D, Hongwei O, Li W, Wang D.
PMID: 34956209
Front Immunol. 2021 Dec 08;12:781185. doi: 10.3389/fimmu.2021.781185. eCollection 2021.

Osteoarthritis (OA) is a serious joint inflammation that leads to cartilage degeneration and joint dysfunction. Mesenchymal stem cells (MSCs) are used as a cell-based therapy that showed promising results in promoting cartilage repair. However, recent studies and clinical trials...

Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model.

Frontiers in immunology

Alahdal M, Huang R, Duan L, Zhiqin D, Hongwei O, Li W, Wang D.
PMID: 34956209
Front Immunol. 2021 Dec 08;12:781185. doi: 10.3389/fimmu.2021.781185. eCollection 2021.

Osteoarthritis (OA) is a serious joint inflammation that leads to cartilage degeneration and joint dysfunction. Mesenchymal stem cells (MSCs) are used as a cell-based therapy that showed promising results in promoting cartilage repair. However, recent studies and clinical trials...

Showing 1 to 12 of 59 entries