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Showing 1 to 12 of 43 entries
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Design of Experiment (DOE) Utilization to Develop a Simple and Robust Reversed-Phase HPLC Technique for Related Substances' Estimation of Omeprazole Formulations.

Scientia pharmaceutica

Manranjan VC, Yadav DS, Jogia HA, Chauhan PL.
PMID: 24482772
Sci Pharm. 2013 Aug 12;81(4):1043-56. doi: 10.3797/scipharm.1306-06. Print 2013.

A simple, fast, and sensitive reversed-phase HPLC method with UV detection was developed for the quantitation of omeprazole and its eleven related compounds (impurities) in pharmaceutical formulation using the Thermo Accucore C-18 (50 mm × 4.6 mm, 2.6 μm)...

Erratum to: CBP binding outside of promoters and enhancers in Drosophila melanogaster.

Epigenetics & chromatin

Philip P, Boija A, Vaid R, Churcher AM, Meyers DJ, Cole PA, Mannervik M, Stenberg P.
PMID: 27625704
Epigenetics Chromatin. 2016 Sep 12;9(1):38. doi: 10.1186/s13072-016-0088-y. eCollection 2016.

[This corrects the article DOI: 10.1186/s13072-015-0042-4.].

Colloidally Stable Monolayer Nanosheets with Colorimetric Responses.

Small (Weinheim an der Bergstrasse, Germany)

Hu B, Sun S, Wu B, Wu P.
PMID: 30589208
Small. 2019 Feb;15(5):e1804975. doi: 10.1002/smll.201804975. Epub 2018 Dec 27.

Despite the discovery of chromogenic-layered materials for decades of years, fabrication of colloidally stable monolayer organic 2D nanosheets in aqueous media with colorimetric responses is still challenging. Herein reported is the first solution synthesis of chromic monolayer nanosheets via...

A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.

Brain : a journal of neurology

Magusali N, Graham AC, Piers TM, Panichnantakul P, Yaman U, Shoai M, Reynolds RH, Botia JA, Brookes KJ, Guetta-Baranes T, Bellou E, Bayram S, Sokolova D, Ryten M, Sala Frigerio C, Escott-Price V, Morgan K, Pocock JM, Hardy J, Salih DA.
PMID: 34619763
Brain. 2021 Dec 31;144(12):3727-3741. doi: 10.1093/brain/awab337.

Recently, we reported oligoadenylate synthetase 1 (OAS1) contributed to the risk of Alzheimer's disease, by its enrichment in transcriptional networks expressed by microglia. However, the function of OAS1 within microglia was not known. Using genotyping from 1313 individuals with...

Comparison of Hemodynamic Visualization in Cerebral Arteries: Can Magnetic Resonance Imaging Replace Computational Fluid Dynamics?.

Journal of personalized medicine

Ngo MT, Lee UY, Ha H, Jin N, Chung GH, Kwak YG, Jung J, Kwak HS.
PMID: 33808514
J Pers Med. 2021 Mar 30;11(4). doi: 10.3390/jpm11040253.

A multimodality approach was applied using four-dimensional flow magnetic resonance imaging (4D flow MRI), time-of-flight magnetic resonance angiography (TOF-MRA) signal intensity gradient (SIG), and computational fluid dynamics (CFD) to investigate the 3D blood flow characteristics and wall shear stress...

Interfacial Activity of Lipoprotein (a) Isoforms with a Variable Number of Kringle IV Type 2 Repeats: A New Indicator of Cardiovascular Risk?.

Annals of clinical and laboratory science

Santonastaso A, Boria A, Paboeuf G, Beaufils S, Bolanos-Garcia VM, Vié V, Scotti C.
PMID: 34921033
Ann Clin Lab Sci. 2021 Nov;51(6):795-804.

OBJECTIVE: Lipoprotein (a) [Lp(a)] is an LDL-like particle constituted by lipids, apolipoprotein B100 and apolipoprotein (a) [apo(a)], a multidomain glycoprotein whose molecular mass is dependent on the genetically encoded number of Kringle IV type 2 (KIV-2) repeats. Because Lp(a)...

A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.

Brain : a journal of neurology

Magusali N, Graham AC, Piers TM, Panichnantakul P, Yaman U, Shoai M, Reynolds RH, Botia JA, Brookes KJ, Guetta-Baranes T, Bellou E, Bayram S, Sokolova D, Ryten M, Sala Frigerio C, Escott-Price V, Morgan K, Pocock JM, Hardy J, Salih DA.
PMID: 34619763
Brain. 2021 Oct 07; doi: 10.1093/brain/awab337. Epub 2021 Oct 07.

Recently, we reported oligoadenylate synthetase 1 (OAS1) contributed to the risk of Alzheimer's disease, by its enrichment in transcriptional networks expressed by microglia. However, the function of OAS1 within microglia was not known. Using genotyping from 1313 individuals with...

Extraction of Essential Oils of .

TheScientificWorldJournal

Elyemni M, Louaste B, Nechad I, Elkamli T, Bouia A, Taleb M, Chaouch M, Eloutassi N.
PMID: 31057339
ScientificWorldJournal. 2019 Apr 01;2019:3659432. doi: 10.1155/2019/3659432. eCollection 2019.

The extraction of essential oils is generally carried out by two main techniques: azeotropic distillation (hydrodistillation, hydrodiffusion, and steam distillation) and extraction with solvents. However, these traditional methods are a bit expensive, especially since they are extremely energy and...

Pituitary dysfunction and association with fatigue in stroke and other acute brain injury.

Endocrine connections

Booij HA, Gaykema WDC, Kuijpers KAJ, Pouwels MJM, den Hertog HM.
PMID: 29748174
Endocr Connect. 2018 Jun;7(6):R223-R237. doi: 10.1530/EC-18-0147. Epub 2018 May 10.

BACKGROUND: Poststroke fatigue (PSF) is a highly prevalent and debilitating condition. However, the etiology remains incompletely understood. Literature suggests the co-prevalence of pituitary dysfunction (PD) with stroke, and the question raises whether this could be a contributing factor to...

CBP binding outside of promoters and enhancers in Drosophila melanogaster.

Epigenetics & chromatin

Philip P, Boija A, Vaid R, Churcher AM, Meyers DJ, Cole PA, Mannervik M, Stenberg P.
PMID: 26604986
Epigenetics Chromatin. 2015 Nov 24;8:48. doi: 10.1186/s13072-015-0042-4. eCollection 2015.

BACKGROUND: CREB-binding protein (CBP, also known as nejire) is a transcriptional co-activator that is conserved in metazoans. CBP plays an important role in embryonic development and cell differentiation and mutations in CBP can lead to various diseases in humans....

Multicenter, Prospective, Randomized Study of Dexamethasone Intravitreal Implant in Patients with Center-Involved Diabetic Macular Edema in the Asia-Pacific Region.

Clinical ophthalmology (Auckland, N.Z.)

Wei W, Chen Y, Hu B, Zhao M, Han M, Dai H, Uy HS, Chen MY, Wang K, Jiao J, Lou J, Li XY.
PMID: 34675477
Clin Ophthalmol. 2021 Oct 13;15:4097-4108. doi: 10.2147/OPTH.S325618. eCollection 2021.

PURPOSE: To evaluate the safety and efficacy of dexamethasone intravitreal implant 0.7 mg (DEX) compared with laser photocoagulation in patients with diabetic macular edema (DME).PATIENTS AND METHODS: This Phase 3, multicenter, randomized, efficacy evaluator-masked, parallel-group, 12-month clinical study enrolled...

Frontiers in bioengineering and biotechnology

Ha H, Huh HK, Park KJ, Dyverfeldt P, Ebbers T, Kim DH, Yang DH.
PMID: 34950643
Front Bioeng Biotechnol. 2021 Dec 07;9:774954. doi: 10.3389/fbioe.2021.774954. eCollection 2021.

Imaging hemodynamics play an important role in the diagnosis of abnormal blood flow due to vascular and valvular diseases as well as in monitoring the recovery of normal blood flow after surgical or interventional treatment. Recently, characterization of turbulent...

Showing 1 to 12 of 43 entries