Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 227 entries
Sorted by: Best Match Show Resources per page
Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques.

Vaccines

Borggren M, Vinner L, Andresen BS, Grevstad B, Repits J, Melchers M, Elvang TL, Sanders RW, Martinon F, Dereuddre-Bosquet N, Bowles EJ, Stewart-Jones G, Biswas P, Scarlatti G, Jansson M, Heyndrickx L, Grand RL, Fomsgaard A.
PMID: 26344115
Vaccines (Basel). 2013 Jul 19;1(3):305-27. doi: 10.3390/vaccines1030305.

HIV-1 DNA vaccines have many advantageous features. Evaluation of HIV-1 vaccine candidates often starts in small animal models before macaque and human trials. Here, we selected and optimized DNA vaccine candidates through systematic testing in rabbits for the induction...

Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection.

Scientific reports

Feger BJ, Thompson JW, Dubois LG, Kommaddi RP, Foster MW, Mishra R, Shenoy SK, Shibata Y, Kidane YH, Moseley MA, Carnell LS, Bowles DE.
PMID: 27670941
Sci Rep. 2016 Sep 27;6:34091. doi: 10.1038/srep34091.

On Earth, biological systems have evolved in response to environmental stressors, interactions dictated by physical forces that include gravity. The absence of gravity is an extreme stressor and the impact of its absence on biological systems is ill-defined. Astronauts...

Characterization of a Murine Pressure Ulcer Model to Assess Efficacy of Adipose-derived Stromal Cells.

Plastic and reconstructive surgery. Global open

Strong AL, Bowles AC, MacCrimmon CP, Lee SJ, Frazier TP, Katz AJ, Gawronska-Kozak B, Bunnell BA, Gimble JM.
PMID: 25878945
Plast Reconstr Surg Glob Open. 2015 Apr 07;3(3):e334. doi: 10.1097/GOX.0000000000000260. eCollection 2015 Mar.

BACKGROUND: As the world's population lives longer, the number of individuals at risk for pressure ulcers will increase considerably in the coming decades. In developed countries, up to 18% of nursing home residents suffer from pressure ulcers and the...

Liposomal delivery of a phosphodiesterase 3 inhibitor rescues low oxygen-induced ATP release from erythrocytes of humans with type 2 diabetes.

Biochemistry and biophysics reports

Dergunov SA, Bowles EA, Gordon W, Green M, Bierman A, Ellsworth ML, Pinkhassik E, Sprague RS.
PMID: 29124155
Biochem Biophys Rep. 2015 May 30;2:137-142. doi: 10.1016/j.bbrep.2015.05.011. eCollection 2015 Jul.

ATP release from erythrocytes in response to low oxygen tension requires an increase in cAMP, the level of which is regulated by phosphodiesterase 3 (PDE3). Such release is defective in erythrocytes of humans with type 2 diabetes (DM2). This...

A History of Falls is Associated with a Significant Increase in Acute Mortality in Women after Stroke.

Journal of clinical neurology (Seoul, Korea)

Foster EJ, Barlas RS, Wood AD, Bettencourt-Silva JH, Clark AB, Metcalf AK, Bowles KM, Potter JF, Myint PK.
PMID: 29057634
J Clin Neurol. 2017 Oct;13(4):411-421. doi: 10.3988/jcn.2017.13.4.411.

BACKGROUND AND PURPOSE: The risks of falls and fractures increase after stroke. Little is known about the prognostic significance of previous falls and fractures after stroke. This study examined whether having a history of either event is associated with...

Changes in the levels of wheat- and barley-germ agglutinin during embryogenesis in vivo, in vitro and during germination.

Planta

Morris PC, Maddock SE, Jones MG, Bowles DJ.
PMID: 24241525
Planta. 1985 Nov;166(3):407-13. doi: 10.1007/BF00401180.

Radioimmunoassay has been used to measure levels of wheat-germ agglutinin and barley-germ agglutinin during embryogenesis and germination. The two lectins exhibited similar patterns of accumulation during grain maturation in vivo and both decreased to low levels after imbibition of...

Prospects for gene therapy for inherited cardiomyopathies.

Progress in pediatric cardiology

Bowles NE, Bowles K, Towbin JA.
PMID: 11114553
Prog Pediatr Cardiol. 2000 Nov 04;12(1):133-145. doi: 10.1016/s1058-9813(00)00065-5.

Over the last few years the genes responsible for a number of genetic diseases of the cardiovascular system have been identified. These have included X-linked and autosomal dominant dilated cardiomyopathy, and hypertrophic cardiomyopathy. Genetic heterogeneity has been described in...

Signal transduction in plants.

Trends in cell biology

Bowles DJ.
PMID: 14732065
Trends Cell Biol. 1995 Oct;5(10):404-8. doi: 10.1016/s0962-8924(00)89090-x.

No abstract available.

Direct measure of the hydration number of aqueous methane.

Journal of the American Chemical Society

Dec SF, Bowler KE, Stadterman LL, Koh CA, Sloan ED.
PMID: 16402820
J Am Chem Soc. 2006 Jan 18;128(2):414-5. doi: 10.1021/ja055283f.

A hydration number of 20 has been measured for aqueous CH4 in the temperature range 273-298 K on the basis of the simultaneous observation of the 13C isotropic resonance lines of CH4 in both aqueous solution and the dodecahedral...

UNUSUAL ABUNDANCE OF THE GROSBEAK IN EASTERN MASSACHUSETTS.

Science (New York, N.Y.)

Bowles JH.
PMID: 17744198
Science. 1893 Jan 13;21(519):19. doi: 10.1126/science.ns-21.519.19.

No abstract available.

Some properties of carbohydrate-binding proteins (lectins) solubilized from cell walls of Phaseolus aureus.

Planta

Kauss H, Bowles DJ.
PMID: 24424594
Planta. 1976 Jan;130(2):169-74. doi: 10.1007/BF00384415.

From the cell walls of nongrowing segments of mung bean hypocotyls two protein fractions can be solubilized which show carbohydrate binding properties as measured with the hemagglutination assay. The extracts show appreciable binding activity only if the walls are...

First do no harm: interventions during childbirth.

The Journal of perinatal education

Jansen L, Gibson M, Bowles BC, Leach J.
PMID: 24421601
J Perinat Educ. 2013;22(2):83-92. doi: 10.1891/1058-1243.22.2.83.

Although medical and technological advances in maternity care have drastically reduced maternal and infant mortality, these interventions have become commonplace if not routine. Used appropriately, they can be life-saving procedures. Routine use, without valid indications, can transform childbirth from...

Showing 1 to 12 of 227 entries