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Showing 1 to 12 of 492 entries
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Cancer incidence attributable to excess body weight in Alberta in 2012.

CMAJ open

Brenner DR, Poirier AE, Grundy A, Khandwala F, McFadden A, Friedenreich CM.
PMID: 28455439
CMAJ Open. 2017 Apr 28;5(2):E330-E336. doi: 10.9778/cmajo.20160039.

BACKGROUND: Excess body weight has been consistently associated with colorectal, breast, endometrial, esophageal, gall bladder, pancreatic and kidney cancers. The objective of this analysis was to estimate the proportion of total and site-specific cancers attributable to excess body weight...

Radar plots: A novel modality for displaying disparate data on the efficacy of eluxadoline for the treatment of irritable bowel syndrome with diarrhea.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

Brenner DM, Dove LS, Andrae DA, Covington PS, Gutman C, Chey WD.
PMID: 29575372
Neurogastroenterol Motil. 2018 Mar 25;e13331. doi: 10.1111/nmo.13331. Epub 2018 Mar 25.

BACKGROUND: Patients with irritable bowel syndrome with diarrhea (IBS-D) experience a range of abdominal and bowel symptoms; successful management requires alleviation of this constellation of symptoms. Eluxadoline, a locally active mixed μ- and κ-opioid receptor agonist and δ-opioid receptor...

A simple add-on microfluidic appliance for accurately sorting small populations of cells with high fidelity.

Journal of micromechanics and microengineering : structures, devices, and systems

Grad M, Young EF, Smilenov L, Brenner DJ, Attinger D.
PMID: 24409041
J Micromech Microeng. 2013;23(11). doi: 10.1088/0960-1317/23/11/117003.

Current advances in single cell sequencing, gene expression and proteomics require the isolation of single cells, frequently from a very small source population. In this work we describe the design and characterization of a manually operated microfluidic cell sorter...

Fecal DNA-Based Detection of Colorectal Neoplasia.

Current colorectal cancer reports

Turgeon DK, Brenner DE.
PMID: 26078729
Curr Colorectal Cancer Rep. 2007 Oct;3(4):171-177. doi: 10.1007/s11888-007-0027-1.

Human DNA fragments, as well a as whole colonocytes, can be found in stool and interrogated for mutations associated with carcinogenesis. Multiplexed panels of point mutations in fecal DNA improved the sensitivity of cancer detection (51.6%; 95% CI, 34.8%-68%)...

A Bead-Based Microfluidic Approach to Integrated Single-Cell Gene Expression Analysis by Quantitative RT-PCR.

RSC advances

Sun H, Olsen T, Zhu J, Tao J, Ponnaiya B, Amundson SA, Brenner DJ, Lin Q.
PMID: 25883782
RSC Adv. 2015 Jan 01;5(7):4886-4893. doi: 10.1039/C4RA13356K.

Gene expression analysis at the single-cell level is critical to understanding variations among cells in heterogeneous populations. Microfluidic reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is well suited to gene expression assays of single cells. We present a...

A Mechanically Tunable Microfluidic Cell-Trapping Device.

Sensors and actuators. A, Physical

Zhu J, Shang J, Olsen T, Liu K, Brenner D, Lin Q.
PMID: 25821347
Sens Actuators A Phys. 2014 Aug 15;215:197-203. doi: 10.1016/j.sna.2013.10.016.

Controlled manipulation, such as isolation, positioning and trapping of cells, is important in basic biological research and clinical diagnostics. Micro/nanotechnologies have been enabling more effective and efficient cell trapping than possible with conventional platforms. Currently available micro/nanoscale methods for...

Correction: High Throughput Measurement of γH2AX DSB Repair Kinetics in a Healthy Human Population.

PloS one

Sharma PM, Ponnaiya B, Taveras M, Shuryak I, Turner H, Brenner DJ.
PMID: 26098318
PLoS One. 2015 Jun 22;10(6):e0131620. doi: 10.1371/journal.pone.0131620. eCollection 2015.

No abstract available.

Half-life measurement for the rp-process waiting point nuclide 80Zr.

Physical review letters

Ressler JJ, Piechaczek A, Walters WB, Aprahamian A, Wiescher M, Batchelder JC, Bingham CR, Brenner DS, Ginter TN, Gross CJ, Grzywacz R, Kulp D, MacDonald B, Reviol W, Rikovska J, Rykaczewski K, Winger JA, Zganjar EF.
PMID: 11017219
Phys Rev Lett. 2000 Mar 06;84(10):2104-7. doi: 10.1103/PhysRevLett.84.2104.

X-ray bursts have been suggested as a possible site for the astrophysical rp-process. The time scale for the process is governed by beta-decay half-lives of several even-even N = Z waiting point nuclei, in particular, N = Z =...

Dinoflagellates from marine algal blooms produce neurotoxic compounds: effects on free calcium levels in neuronal cells and synaptosomes.

Environmental toxicology and pharmacology

Perovic S, Tretter L, Brümmer F, Wetzler C, Brenner J, Donner G, Schröder HC, Müller WE.
PMID: 10867367
Environ Toxicol Pharmacol. 2000 Jan 01;8(2):83-94. doi: 10.1016/s1382-6689(99)00035-6.

In this report, evidence is presented that the marine unicellular eukaryotic dinoflagellates can cause neurotoxicity very likely by an increase in intracellular free calcium ions ([Ca(2+)](i)). Determinations of the effects of culture supernatants from different clones of the dinoflagellate...

Practical scheme for quantum computation with any two-qubit entangling gate.

Physical review letters

Bremner MJ, Dawson CM, Dodd JL, Gilchrist A, Harrow AW, Mortimer D, Nielsen MA, Osborne TJ.
PMID: 12484981
Phys Rev Lett. 2002 Dec 09;89(24):247902. doi: 10.1103/PhysRevLett.89.247902. Epub 2002 Nov 25.

Which gates are universal for quantum computation? Although it is well known that certain gates on two-level quantum systems (qubits), such as the controlled-not, are universal when assisted by arbitrary one-qubit gates, it has only recently become clear precisely...

Research in medical education.

JAMA

Brauner DJ.
PMID: 12517225
JAMA. 2003 Jan 08;289(2):176; author reply 176. doi: 10.1001/jama.289.2.176-b.

No abstract available.

A combined manipulandum-reinforcement arrangement.

Journal of the experimental analysis of behavior

BREMNER FJ, TROWILL JA.
PMID: 13872796
J Exp Anal Behav. 1962 Jul;5:339-40. doi: 10.1901/jeab.1962.5-339.

No abstract available.

Showing 1 to 12 of 492 entries