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Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System.

ACS central science

Lössl P, Brunner AM, Liu F, Leney AC, Yamashita M, Scheltema RA, Heck AJ.
PMID: 27504491
ACS Cent Sci. 2016 Jul 27;2(7):445-55. doi: 10.1021/acscentsci.6b00053. Epub 2016 Jun 10.

Multisite phosphorylation is a common pathway to regulate protein function, activity, and interaction pattern in vivo, but routine biochemical analysis is often insufficient to identify the number and order of individual phosphorylation reactions and their mechanistic impact on the...

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Lössl P, Brunner AM, Liu F, et al. Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System. ACS Cent Sci. 2016;2(7):445-55doi: 10.1021/acscentsci.6b00053.
Lössl, P., Brunner, A. M., Liu, F., Leney, A. C., Yamashita, M., Scheltema, R. A., & Heck, A. J. (2016). Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System. ACS central science, 2(7), 445-55. https://doi.org/10.1021/acscentsci.6b00053
Lössl, Philip, et al. "Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System." ACS central science vol. 2,7 (2016): 445-55. doi: https://doi.org/10.1021/acscentsci.6b00053
Lössl P, Brunner AM, Liu F, Leney AC, Yamashita M, Scheltema RA, Heck AJ. Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System. ACS Cent Sci. 2016 Jul 27;2(7):445-55. doi: 10.1021/acscentsci.6b00053. Epub 2016 Jun 10. PMID: 27504491; PMCID: PMC4965854.
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Pure White Cell Aplasia and Necrotizing Myositis.

Case reports in hematology

Kim PG, Suh J, Adelman MW, Oduro K, Williams E, Brunner AM, Kuter DJ.
PMID: 27073704
Case Rep Hematol. 2016;2016:4161679. doi: 10.1155/2016/4161679. Epub 2016 Mar 17.

Pure white cell aplasia (PWCA) is a rare hematologic disorder characterized by the absence of neutrophil lineages in the bone marrow with intact megakaryopoiesis and erythropoiesis. PWCA has been associated with autoimmune, drug-induced, and viral exposures. Here, we report...

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Kim PG, Suh J, Adelman MW, et al. Pure White Cell Aplasia and Necrotizing Myositis. Case Rep Hematol. 2016;2016:4161679doi: 10.1155/2016/4161679.
Kim, P. G., Suh, J., Adelman, M. W., Oduro, K., Williams, E., Brunner, A. M., & Kuter, D. J. (2016). Pure White Cell Aplasia and Necrotizing Myositis. Case reports in hematology, 20164161679. https://doi.org/10.1155/2016/4161679
Kim, Peter Geon, et al. "Pure White Cell Aplasia and Necrotizing Myositis." Case reports in hematology vol. 2016 (2016): 4161679. doi: https://doi.org/10.1155/2016/4161679
Kim PG, Suh J, Adelman MW, Oduro K, Williams E, Brunner AM, Kuter DJ. Pure White Cell Aplasia and Necrotizing Myositis. Case Rep Hematol. 2016;2016:4161679. doi: 10.1155/2016/4161679. Epub 2016 Mar 17. PMID: 27073704; PMCID: PMC4814688.
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Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on .

Geophysical research letters

Atreya SK, Trainer MG, Franz HB, Wong MH, Manning HL, Malespin CA, Mahaffy PR, Conrad PG, Brunner AE, Leshin LA, Jones JH, Webster CR, Owen TC, Pepin RO, Navarro-González R.
PMID: 25821261
Geophys Res Lett. 2013 Nov 16;40(21):5605-5609. doi: 10.1002/2013GL057763. Epub 2013 Nov 06.

[1] The quadrupole mass spectrometer of the Sample Analysis at Mars (SAM) instrument on

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Atreya SK, Trainer MG, Franz HB, et al. Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on . Geophys Res Lett. 2013;40(21):5605-5609doi: 10.1002/2013GL057763.
Atreya, S. K., Trainer, M. G., Franz, H. B., Wong, M. H., Manning, H. L., Malespin, C. A., Mahaffy, P. R., Conrad, P. G., Brunner, A. E., Leshin, L. A., Jones, J. H., Webster, C. R., Owen, T. C., Pepin, R. O., & Navarro-González, R. (2013). Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on . Geophysical research letters, 40(21), 5605-5609. https://doi.org/10.1002/2013GL057763
Atreya, Sushil K, et al. "Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on ." Geophysical research letters vol. 40,21 (2013): 5605-5609. doi: https://doi.org/10.1002/2013GL057763
Atreya SK, Trainer MG, Franz HB, Wong MH, Manning HL, Malespin CA, Mahaffy PR, Conrad PG, Brunner AE, Leshin LA, Jones JH, Webster CR, Owen TC, Pepin RO, Navarro-González R. Primordial argon isotope fractionation in the atmosphere of Mars measured by the SAM instrument on . Geophys Res Lett. 2013 Nov 16;40(21):5605-5609. doi: 10.1002/2013GL057763. Epub 2013 Nov 06. PMID: 25821261; PMCID: PMC4373143.
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Turbidite Megabeds in an Oceanic Rift Valley Recording Jökulhlaups of Late Pleistocene Glacial Lakes of the Western United States.

The Journal of geology

Zuffa GG, Normark WR, Serra F, Brunner CA.
PMID: 10769156
J Geol. 2000 May;108(3):253-274. doi: 10.1086/314404.

Escanaba Trough is the southernmost segment of the Gorda Ridge and is filled by sandy turbidites locally exceeding 500 m in thickness. New results from Ocean Drilling Program (ODP) Sites 1037 and 1038 that include accelerator mass spectrometry (AMS)...

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Zuffa GG, Normark WR, Serra F, et al. Turbidite Megabeds in an Oceanic Rift Valley Recording Jökulhlaups of Late Pleistocene Glacial Lakes of the Western United States. J Geol. 2000;108(3):253-274doi: 10.1086/314404.
Zuffa, G. G., Normark, W. R., Serra, F., & Brunner, C. A. (2000). Turbidite Megabeds in an Oceanic Rift Valley Recording Jökulhlaups of Late Pleistocene Glacial Lakes of the Western United States. The Journal of geology, 108(3), 253-274. https://doi.org/10.1086/314404
Zuffa, et al. "Turbidite Megabeds in an Oceanic Rift Valley Recording Jökulhlaups of Late Pleistocene Glacial Lakes of the Western United States." The Journal of geology vol. 108,3 (2000): 253-274. doi: https://doi.org/10.1086/314404
Zuffa GG, Normark WR, Serra F, Brunner CA. Turbidite Megabeds in an Oceanic Rift Valley Recording Jökulhlaups of Late Pleistocene Glacial Lakes of the Western United States. J Geol. 2000 May;108(3):253-274. doi: 10.1086/314404. PMID: 10769156.
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Determination of the quantitative relationship of outer and inner membrane proteins in rat liver mitochondria by means of enzymology and electron microscopy.

FEBS letters

Brunner G, Bücher T.
PMID: 11947350
FEBS Lett. 1970 Jan 26;6(2):105-108. doi: 10.1016/0014-5793(70)80013-8.

No abstract available.

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Brunner G, Bücher T. Determination of the quantitative relationship of outer and inner membrane proteins in rat liver mitochondria by means of enzymology and electron microscopy. FEBS Lett. 1970;6(2):105-108doi: 10.1016/0014-5793(70)80013-8.
Brunner, G., & Bücher, T. (1970). Determination of the quantitative relationship of outer and inner membrane proteins in rat liver mitochondria by means of enzymology and electron microscopy. FEBS letters, 6(2), 105-108. https://doi.org/10.1016/0014-5793(70)80013-8
Brunner, G, and Bücher, T. "Determination of the quantitative relationship of outer and inner membrane proteins in rat liver mitochondria by means of enzymology and electron microscopy." FEBS letters vol. 6,2 (1970): 105-108. doi: https://doi.org/10.1016/0014-5793(70)80013-8
Brunner G, Bücher T. Determination of the quantitative relationship of outer and inner membrane proteins in rat liver mitochondria by means of enzymology and electron microscopy. FEBS Lett. 1970 Jan 26;6(2):105-108. doi: 10.1016/0014-5793(70)80013-8. PMID: 11947350.
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Why Objective Monitoring of Compliance is Important in the Management of Hypertension.

Journal of clinical hypertension (Greenwich, Conn.)

Bertholet N, Favrat B, Fallab-Stubi CL, Brunner HR, Burnier M.
PMID: 11416658
J Clin Hypertens (Greenwich). 2000 Jul;2(4):258-262.

Hypertensive patients often experience poor adherence to treatment, a frequent cause of uncontrolled blood pressure. In this study, we have evaluated whether or not the use of electronic monitoring for drug adherence is a useful approach to identify and...

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Bertholet N, Favrat B, Fallab-Stubi CL, et al. Why Objective Monitoring of Compliance is Important in the Management of Hypertension. J Clin Hypertens (Greenwich). 2000;2(4):258-262
Bertholet, N., Favrat, B., Fallab-Stubi, C. L., Brunner, H. R., & Burnier, M. (2000). Why Objective Monitoring of Compliance is Important in the Management of Hypertension. Journal of clinical hypertension (Greenwich, Conn.), 2(4), 258-262.
Bertholet, Nicolas, et al. "Why Objective Monitoring of Compliance is Important in the Management of Hypertension." Journal of clinical hypertension (Greenwich, Conn.) vol. 2,4 (2000): 258-262.
Bertholet N, Favrat B, Fallab-Stubi CL, Brunner HR, Burnier M. Why Objective Monitoring of Compliance is Important in the Management of Hypertension. J Clin Hypertens (Greenwich). 2000 Jul;2(4):258-262. PMID: 11416658.
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Rapid Site-Directed Mutagenesis Using Two-PCR-Generated DNA Fragments Reproducing the Plasmid Template.

Journal of biomedicine & biotechnology

Allemandou F, Nussberger J, Brunner HR, Brakch N.
PMID: 12975535
J Biomed Biotechnol. 2003;2003(3):202-207. doi: 10.1155/S1110724303209141.

We describe a new rapid and efficient polymerase chain reaction (PCR)-based site-directed mutagenesis method. This procedure is effective with any plasmid and it employs four oligonucleotide primers. One primer contains the desired mutation, the second is oriented in the...

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Allemandou F, Nussberger J, Brunner HR, et al. Rapid Site-Directed Mutagenesis Using Two-PCR-Generated DNA Fragments Reproducing the Plasmid Template. J Biomed Biotechnol. 2003;2003(3):202-207doi: 10.1155/S1110724303209141.
Allemandou, F., Nussberger, J., Brunner, H. R., & Brakch, N. (2003). Rapid Site-Directed Mutagenesis Using Two-PCR-Generated DNA Fragments Reproducing the Plasmid Template. Journal of biomedicine & biotechnology, 2003(3), 202-207. https://doi.org/10.1155/S1110724303209141
Allemandou, Flore, et al. "Rapid Site-Directed Mutagenesis Using Two-PCR-Generated DNA Fragments Reproducing the Plasmid Template." Journal of biomedicine & biotechnology vol. 2003,3 (2003): 202-207. doi: https://doi.org/10.1155/S1110724303209141
Allemandou F, Nussberger J, Brunner HR, Brakch N. Rapid Site-Directed Mutagenesis Using Two-PCR-Generated DNA Fragments Reproducing the Plasmid Template. J Biomed Biotechnol. 2003;2003(3):202-207. doi: 10.1155/S1110724303209141. PMID: 12975535; PMCID: PMC400210.
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Forestry's fertile crescent: the application of biotechnology to forest trees.

Plant biotechnology journal

Campbell MM, Brunner AM, Jones HM, Strauss SH.
PMID: 17156028
Plant Biotechnol J. 2003 May;1(3):141-54. doi: 10.1046/j.1467-7652.2003.00020.x.

Relative to crop plants, the domestication of forest trees is still in its infancy. For example, the domestication of many crop plants was initiated some 10,000 years ago in the so-called 'Fertile Crescent' of the Middle East. By contrast,...

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Campbell MM, Brunner AM, Jones HM, et al. Forestry's fertile crescent: the application of biotechnology to forest trees. Plant Biotechnol J. 2003;1(3):141-54doi: 10.1046/j.1467-7652.2003.00020.x.
Campbell, M. M., Brunner, A. M., Jones, H. M., & Strauss, S. H. (2003). Forestry's fertile crescent: the application of biotechnology to forest trees. Plant biotechnology journal, 1(3), 141-54. https://doi.org/10.1046/j.1467-7652.2003.00020.x
Campbell, Malcolm M, et al. "Forestry's fertile crescent: the application of biotechnology to forest trees." Plant biotechnology journal vol. 1,3 (2003): 141-54. doi: https://doi.org/10.1046/j.1467-7652.2003.00020.x
Campbell MM, Brunner AM, Jones HM, Strauss SH. Forestry's fertile crescent: the application of biotechnology to forest trees. Plant Biotechnol J. 2003 May;1(3):141-54. doi: 10.1046/j.1467-7652.2003.00020.x. PMID: 17156028.
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Sleep and periodic limb movements in corticobasal degeneration.

Sleep medicine

Wetter TC, Brunner H, Collado-Seidel V, Trenkwalder C, Winkelmann J.
PMID: 14592251
Sleep Med. 2002 Jan;3(1):33-6. doi: 10.1016/s1389-9457(01)00097-1.

Corticobasal degeneration (CBD) exhibits distinct features of akinesia, the 'alien limb' sign and cortical myoclonus. We report a 63-year old woman with a history of CBD for 18 months who was studied twice using all-night polysomnography with an interval...

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Wetter TC, Brunner H, Collado-Seidel V, et al. Sleep and periodic limb movements in corticobasal degeneration. Sleep Med. 2002;3(1):33-6doi: 10.1016/s1389-9457(01)00097-1.
Wetter, T. C., Brunner, H., Collado-Seidel, V., Trenkwalder, C., & Winkelmann, J. (2002). Sleep and periodic limb movements in corticobasal degeneration. Sleep medicine, 3(1), 33-6. https://doi.org/10.1016/s1389-9457(01)00097-1
Wetter, Thomas C, et al. "Sleep and periodic limb movements in corticobasal degeneration." Sleep medicine vol. 3,1 (2002): 33-6. doi: https://doi.org/10.1016/s1389-9457(01)00097-1
Wetter TC, Brunner H, Collado-Seidel V, Trenkwalder C, Winkelmann J. Sleep and periodic limb movements in corticobasal degeneration. Sleep Med. 2002 Jan;3(1):33-6. doi: 10.1016/s1389-9457(01)00097-1. PMID: 14592251.
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Tandem cyclopropanation with dibromomethane under Grignard conditions.

The Journal of organic chemistry

Brunner G, Eberhard L, Oetiker J, Schröder F.
PMID: 18783276
J Org Chem. 2008 Oct 03;73(19):7543-54. doi: 10.1021/jo8007397. Epub 2008 Sep 11.

Tertiary Grignard reagents and dibromomethane efficiently cyclopropanate allylic (and certain homoallylic) magnesium and lithium alcoholates at ambient temperature in ether solvents. Lithium (homo)allyl alcoholates are directly cyclopropanated with magnesium and CH2Br2 under Barbier conditions at higher temperatures. The reaction...

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Brunner G, Eberhard L, Oetiker J, et al. Tandem cyclopropanation with dibromomethane under Grignard conditions. J Org Chem. 2008;73(19):7543-54doi: 10.1021/jo8007397.
Brunner, G., Eberhard, L., Oetiker, J., & Schröder, F. (2008). Tandem cyclopropanation with dibromomethane under Grignard conditions. The Journal of organic chemistry, 73(19), 7543-54. https://doi.org/10.1021/jo8007397
Brunner, Gerhard, et al. "Tandem cyclopropanation with dibromomethane under Grignard conditions." The Journal of organic chemistry vol. 73,19 (2008): 7543-54. doi: https://doi.org/10.1021/jo8007397
Brunner G, Eberhard L, Oetiker J, Schröder F. Tandem cyclopropanation with dibromomethane under Grignard conditions. J Org Chem. 2008 Oct 03;73(19):7543-54. doi: 10.1021/jo8007397. Epub 2008 Sep 11. PMID: 18783276.
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Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs.

Viruses

Wainberg MA, Brenner BG.
PMID: 21994627
Viruses. 2010 Nov;2(11):2493-508. doi: 10.3390/v2112493. Epub 2010 Nov 11.

Despite the fact that over 90% of HIV-1 infected people worldwide harbor non-subtype B variants of HIV-1, knowledge of resistance mutations in non-B HIV-1 and their clinical relevance is limited. Due to historical delays in access to antiretroviral therapy...

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Wainberg MA, Brenner BG. Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs. Viruses. 2010;2(11):2493-508doi: 10.3390/v2112493.
Wainberg, M. A., & Brenner, B. G. (2010). Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs. Viruses, 2(11), 2493-508. https://doi.org/10.3390/v2112493
Wainberg, Mark A, and Brenner, Bluma G. "Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs." Viruses vol. 2,11 (2010): 2493-508. doi: https://doi.org/10.3390/v2112493
Wainberg MA, Brenner BG. Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs. Viruses. 2010 Nov;2(11):2493-508. doi: 10.3390/v2112493. Epub 2010 Nov 11. PMID: 21994627; PMCID: PMC3185584.
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Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language.

Nature communications

Blok LS, Rousseau J, Twist J, Ehresmann S, Takaku M, Venselaar H, Rodan LH, Nowak CB, Douglas J, Swoboda KJ, Steeves MA, Sahai I, Stumpel CTRM, Stegmann APA, Wheeler P, Willing M, Fiala E, Kochhar A, Gibson WT, Cohen ASA, Agbahovbe R, Innes AM, Au PYB, Rankin J, Anderson IJ, Skinner SA, Louie RJ, Warren HE, Afenjar A, Keren B, Nava C, Buratti J, Isapof A, Rodriguez D, Lewandowski R, Propst J, van Essen T, Choi M, Lee S, Chae JH, Price S, Schnur RE, Douglas G, Wentzensen IM, Zweier C, Reis A, Bialer MG, Moore C, Koopmans M, Brilstra EH, Monroe GR, van Gassen KLI, van Binsbergen E, Newbury-Ecob R, Bownass L, Bader I, Mayr JA, Wortmann SB, Jakielski KJ, Strand EA, Kloth K, Bierhals T, Roberts JD, Petrovich RM, Machida S, Kurumizaka H, Lelieveld S, Pfundt R, Jansen S, Deriziotis P, Faivre L, Thevenon J, Assoum M, Shriberg L, Kleefstra T, Brunner HG, Wade PA, Fisher SE, Campeau PM.
PMID: 30770872
Nat Commun. 2019 Feb 15;10(1):883. doi: 10.1038/s41467-019-08800-2.

The original version of this Article contained an error in the spelling of the author Laurence Faivre, which was incorrectly given as Laurence Faive. This has now been corrected in both the PDF and HTML versions of the Article.

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Blok LS, Rousseau J, Twist J, et al. Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language. Nat Commun. 2019;10(1):883doi: 10.1038/s41467-019-08800-2.
Blok, L. S., Rousseau, J., Twist, J., Ehresmann, S., Takaku, M., Venselaar, H., Rodan, L. H., Nowak, C. B., Douglas, J., Swoboda, K. J., Steeves, M. A., Sahai, I., Stumpel, C. T. R. M., Stegmann, A. P. A., Wheeler, P., Willing, M., Fiala, E., Kochhar, A., Gibson, W. T., Cohen, A. S. A., Agbahovbe, R., Innes, A. M., Au, P. Y. B., Rankin, J., Anderson, I. J., Skinner, S. A., Louie, R. J., Warren, H. E., Afenjar, A., Keren, B., Nava, C., Buratti, J., Isapof, A., Rodriguez, D., Lewandowski, R., Propst, J., van Essen, T., Choi, M., Lee, S., Chae, J. H., Price, S., Schnur, R. E., Douglas, G., Wentzensen, I. M., Zweier, C., Reis, A., Bialer, M. G., Moore, C., Koopmans, M., Brilstra, E. H., Monroe, G. R., van Gassen, K. L. I., van Binsbergen, E., Newbury-Ecob, R., Bownass, L., Bader, I., Mayr, J. A., Wortmann, S. B., Jakielski, K. J., Strand, E. A., Kloth, K., Bierhals, T., Roberts, J. D., Petrovich, R. M., Machida, S., Kurumizaka, H., Lelieveld, S., Pfundt, R., Jansen, S., Deriziotis, P., Faivre, L., Thevenon, J., Assoum, M., Shriberg, L., Kleefstra, T., Brunner, H. G., Wade, P. A., Fisher, S. E., & Campeau, P. M. (2019). Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language. Nature communications, 10(1), 883. https://doi.org/10.1038/s41467-019-08800-2
Blok, Lot Snijders, et al. "Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language." Nature communications vol. 10,1 (2019): 883. doi: https://doi.org/10.1038/s41467-019-08800-2
Blok LS, Rousseau J, Twist J, Ehresmann S, Takaku M, Venselaar H, Rodan LH, Nowak CB, Douglas J, Swoboda KJ, Steeves MA, Sahai I, Stumpel CTRM, Stegmann APA, Wheeler P, Willing M, Fiala E, Kochhar A, Gibson WT, Cohen ASA, Agbahovbe R, Innes AM, Au PYB, Rankin J, Anderson IJ, Skinner SA, Louie RJ, Warren HE, Afenjar A, Keren B, Nava C, Buratti J, Isapof A, Rodriguez D, Lewandowski R, Propst J, van Essen T, Choi M, Lee S, Chae JH, Price S, Schnur RE, Douglas G, Wentzensen IM, Zweier C, Reis A, Bialer MG, Moore C, Koopmans M, Brilstra EH, Monroe GR, van Gassen KLI, van Binsbergen E, Newbury-Ecob R, Bownass L, Bader I, Mayr JA, Wortmann SB, Jakielski KJ, Strand EA, Kloth K, Bierhals T, Roberts JD, Petrovich RM, Machida S, Kurumizaka H, Lelieveld S, Pfundt R, Jansen S, Deriziotis P, Faivre L, Thevenon J, Assoum M, Shriberg L, Kleefstra T, Brunner HG, Wade PA, Fisher SE, Campeau PM. Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language. Nat Commun. 2019 Feb 15;10(1):883. doi: 10.1038/s41467-019-08800-2. PMID: 30770872; PMCID: PMC6377600.
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