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Showing 1 to 12 of 42 entries
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An Unusual Case of Metastatic Functional Thyroid Carcinoma With a Remarkable Treatment Response to Radioactive Iodine.

Journal of the Endocrine Society

Geliebter A, Brutsaert EF, Surks MI.
PMID: 29264468
J Endocr Soc. 2017 Aug 08;1(12):1440-1444. doi: 10.1210/js.2017-00296. eCollection 2017 Dec 01.

Functional thyroid carcinoma is an unusual cause of thyrotoxicosis. We describe the clinical presentation and treatment of a patient with thyrotoxicosis due to functional thyroid carcinoma and Graves disease, and discuss potential mechanisms causing the thyrotoxicosis. A 79-year-old woman...

Measuring Proviral HIV-1 DNA: Hurdles and Improvements to an Assay Monitoring Integration Events Utilising Human .

Life (Basel, Switzerland)

Malatinkova E, Thomas J, De Spiegelaere W, Rutsaert S, Geretti AM, Pollakis G, Paxton WA, Vandekerckhove L, Ruggiero A.
PMID: 34947941
Life (Basel). 2021 Dec 16;11(12). doi: 10.3390/life11121410.

Integrated HIV-1 DNA persists despite antiretroviral therapy and can fuel viral rebound following treatment interruption. Hence, methods to specifically measure the integrated HIV-1 DNA portion only are important to monitor the reservoir in eradication trials. Here, we provide an...

Severity of central sleep apnea does not affect sleeping oxygen saturation during ascent to high altitude.

Journal of applied physiology (Bethesda, Md. : 1985)

Bird JD, Kalker A, Rimke AN, Chan JS, Chan G, Saran G, Jendzjowsky NG, Wilson RJA, Brutsaert TD, Sherpa MT, Day TA.
PMID: 34435507
J Appl Physiol (1985). 2021 Nov 01;131(5):1432-1443. doi: 10.1152/japplphysiol.00363.2021. Epub 2021 Aug 26.

Central sleep apnea (CSA) is characterized by periodic breathing (PB) during sleep, defined as intermittent periods of apnea/hypopnea and hyperventilation, with associated acute fluctuations in oxyhemoglobin saturation (SO

Cardiorespiratory hysteresis during incremental high-altitude ascent-descent quantifies the magnitude of ventilatory acclimatization.

Experimental physiology

Leacy JK, Linares AM, Zouboules SM, Rampuri ZH, Bird JD, Herrington BA, Mann LM, Soriano JE, Thrall SF, Kalker A, Brutsaert TD, O'Halloran KD, Sherpa MT, Day TA.
PMID: 32421248
Exp Physiol. 2021 Jan;106(1):139-150. doi: 10.1113/EP088488. Epub 2020 Jun 30.

NEW FINDINGS: What is the central question of this study? We assessed the utility of a new metric for quantifying ventilatory acclimatization to high altitude, derived from differential ascent and descent steady-state cardiorespiratory variables (i.e. hysteresis). Furthermore, we aimed...

Benefits of antiretroviral therapy initiation during acute HIV infection.

Acta clinica Belgica

De Clercq J, Rutsaert S, De Scheerder MA, Verhofstede C, Callens S, Vandekerckhove L.
PMID: 32468932
Acta Clin Belg. 2020 May 29;1-9. doi: 10.1080/17843286.2020.1770413. Epub 2020 May 29.

OBJECTIVES: In the last decade, there has been increasing scientific and legislative focus on antiretroviral treatment (ART) for all people living with HIV. Especially early ART initiation, preferably during acute HIV infection, has been named as a promising strategy,...

Measuring Proviral HIV-1 DNA: Hurdles and Improvements to an Assay Monitoring Integration Events Utilising Human .

Life (Basel, Switzerland)

Malatinkova E, Thomas J, De Spiegelaere W, Rutsaert S, Geretti AM, Pollakis G, Paxton WA, Vandekerckhove L, Ruggiero A.
PMID: 34947941
Life (Basel). 2021 Dec 16;11(12). doi: 10.3390/life11121410.

Integrated HIV-1 DNA persists despite antiretroviral therapy and can fuel viral rebound following treatment interruption. Hence, methods to specifically measure the integrated HIV-1 DNA portion only are important to monitor the reservoir in eradication trials. Here, we provide an...

State of the art on heart failure syndrome.

Journal of cardiac failure

Sasayama S, Ross J, Brutsaert D.
PMID: 8951553
J Card Fail. 1996 Dec;2(4):V-VI. doi: 10.1016/s1071-9164(96)80051-0.

No abstract available.

Digitizing two dimensional echocardiographical images.

Acta cardiologica. Supplementum

van Ocken E, Claes VA, Brutsaert DL.
PMID: 6977969
Acta Cardiol Suppl. 1981;26:81-3.

No abstract available.

Sticking with the old seed: Input value chains and the challenges to deliver genetic gains to smallholder maize farmers.

Outlook on agriculture

Rutsaert P, Donovan J.
PMID: 32641870
Outlook Agric. 2020 Mar;49(1):39-49. doi: 10.1177/0030727019900520. Epub 2020 Jan 20.

The Kenyan maize seed sector exhibits high hybrid adoption rates, a growing number of seed companies, and an extensive agro-dealer network. Nonetheless, maize yields remain low and uptake of new, stress-tolerant varieties has been disappointing. This article investigates interactions...

Neurovascular Coupling Remains Intact During Incremental Ascent to High Altitude (4240 m) in Acclimatized Healthy Volunteers.

Frontiers in physiology

Leacy JK, Zouboules SM, Mann CR, Peltonen JDB, Saran G, Nysten CE, Nysten HE, Brutsaert TD, O'Halloran KD, Sherpa MT, Day TA.
PMID: 30546319
Front Physiol. 2018 Nov 28;9:1691. doi: 10.3389/fphys.2018.01691. eCollection 2018.

Neurovascular coupling (NVC) is the temporal link between neuronal metabolic activity and regional cerebral blood flow (CBF), supporting adequate delivery of nutrients. Exposure to high altitude (HA) imposes several stressors, including hypoxia and hypocapnia, which modulate cerebrovascular tone in...

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study.

Journal of virus eradication

Rutsaert S, Steens JM, Gineste P, Cole B, Kint S, Barrett PN, Tazi J, Scherrer D, Ehrlich HJ, Vandekerckhove L.
PMID: 30800421
J Virus Erad. 2019 Jan 01;5(1):10-22.

OBJECTIVES: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863).METHODS: Randomised, double-blind, placebo-controlled, Phase IIa study in individuals living with HIV-1 on...

A 54-year-old Philippine sailor with fever and jaundice.

Acta clinica Belgica

Van Dijck C, Van Esbroeck M, Rutsaert R.
PMID: 27075788
Acta Clin Belg. 2016 Oct;71(5):319-322. doi: 10.1080/17843286.2015.1105606. Epub 2016 Feb 03.

A 54-year-old man presented with fever, vomiting, jaundice and conjunctival injection. These clinical signs, together with the presence of mild inflammation, hepatitis and severe acute kidney injury, lead to the suspicion of leptospirosis. Infection was serologically confirmed and treatment...

Showing 1 to 12 of 42 entries