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Showing 1 to 12 of 214 entries
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Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.

ACS medicinal chemistry letters

Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M.
PMID: 28947941
ACS Med Chem Lett. 2017 Jul 31;8(9):941-946. doi: 10.1021/acsmedchemlett.7b00229. eCollection 2017 Sep 14.

We report the synthesis, biological evaluation, and structural study of a series of substituted heteroaryl-pyrazole carboxylic acid derivatives. These compounds have been developed as inhibitors of specific isoforms of carbonic anhydrase (CA), with potential as prototypes of a new...

First Robotic-Assisted Dual Kidney Transplant: Surgical Technique and Report of a Case With 24-month Follow-up.

Transplantation direct

Frongia M, Cadoni R, Solinas A.
PMID: 27500234
Transplant Direct. 2015 Oct 13;1(9):e34. doi: 10.1097/TXD.0000000000000547. eCollection 2015 Oct.

BACKGROUND: Open surgery is the gold standard procedure for kidney transplantation. There is a strong rationale for using minimally invasive surgery in patients with end-stage renal disease. A robotic-assisted dual kidney transplant was performed for the first time at...

Diagnostic sensitivity of thyroid autoantibodies assessed in a population-based, cross-sectional study in adults.

Auto- immunity highlights

Bosi E, Bianchi R, Ruotolo G, Bazzigaluppi E, Belloni C, Calori G, Girardi AM, Garancini MP, Scavini M.
PMID: 26000111
Auto Immun Highlights. 2010 Nov 04;1(2):83-6. doi: 10.1007/s13317-010-0012-6. eCollection 2010 Nov.

The aim of this study was to estimate the diagnostic sensitivity of thyroid autoantibodies in individuals with a case-mix of subjects with thyroid disease representing that of the general population. We measured thyroid microsome (TMA), thyroid peroxidase (TPO), thyroglobulin...

Benzoxaboroles as Efficient Inhibitors of the β-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study.

ACS medicinal chemistry letters

Nocentini A, Cadoni R, Del Prete S, Capasso C, Dumy P, Gratteri P, Supuran CT, Winum JY.
PMID: 29152053
ACS Med Chem Lett. 2017 Oct 20;8(11):1194-1198. doi: 10.1021/acsmedchemlett.7b00369. eCollection 2017 Nov 09.

A series of 6-substituted benzoxaboroles were investigated as inhibitors of the β-class carbonic anhydrase from three pathogenic fungi (

Challenges and opportunities in image guided particle therapy.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Riboldi M, Baroni G.
PMID: 26737470
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:5227-30. doi: 10.1109/EMBC.2015.7319570.

The application of biomedical imaging and image processing to radiation therapy with accelerated particles has unique challenges. The potential of particle therapy to precisely tailor the dose distribution around the target volume needs to account for the intrinsic sensitivity...

Household Food Items Toxic to Dogs and Cats.

Frontiers in veterinary science

Cortinovis C, Caloni F.
PMID: 27047944
Front Vet Sci. 2016 Mar 22;3:26. doi: 10.3389/fvets.2016.00026. eCollection 2016.

Several foods that are perfectly suitable for human consumption can be toxic to dogs and cats. Food-associated poisoning cases involving the accidental ingestion of chocolate and chocolate-based products, Allium spp. (onion, garlic, leek, and chives), macadamia nuts, Vitis vinifera...

[Claude Bernard and the boundaries of experimental physiology].

Historia, ciencias, saude--Manguinhos

Caponi G.
PMID: 11789533
Hist Cienc Saude Manguinhos. 2001 Jul-Aug;8(2):375-406. doi: 10.1590/s0104-59702001000300005.

Claude Bernard set some of the boundaries for the program developed by himself in his Introduction à l'étude de la médicine expérimentale, which seems to be questioned by the very existence of biology of evolution and biology of development....

Order-disorder character and twinning in the structure of a new synthetic titanosilicate: (Ba,Sr)4Ti6Si4O24 x H2O.

Acta crystallographica. Section B, Structural science

Cadoni M, Bloise A, Ferraris G, Merlino S.
PMID: 19029696
Acta Crystallogr B. 2008 Dec;64:669-75. doi: 10.1107/S0108768108032631. Epub 2008 Nov 08.

Prismatic crystals of the title compound, up to 100 microm long and {001} twinned by metric merohedry, were obtained as a side-product of a hydrothermal run devoted to synthesizing the heterophyllosilicate lamprophyllite. Single-crystal X-ray diffraction data were collected on...

Multidimensional characterization, Landau levels and Density of States in epitaxial graphene grown on SiC substrates.

Nanoscale research letters

Camara N, Jouault B, Jabakhanji B, Caboni A, Tiberj A, Consejo C, Godignon P, Camassel J.
PMID: 21711670
Nanoscale Res Lett. 2011 Feb 14;6(1):141. doi: 10.1186/1556-276X-6-141.

Using high-temperature annealing conditions with a graphite cap covering the C-face of, both, on axis and 8° off-axis 4H-SiC samples, large and homogeneous single epitaxial graphene layers have been grown. Raman spectroscopy shows evidence of the almost free-standing character...

Distributions of brine and bacteria in beef primal cuts injected with brine without, or before or after mechanical tenderizing.

Meat science

Gill CO, Uttaro B, Badoni M, Zawadski S.
PMID: 22062611
Meat Sci. 2008 May;79(1):181-7. doi: 10.1016/j.meatsci.2007.08.012. Epub 2007 Aug 31.

Eye of round primal cuts of beef were injected with brines containing a dye and Listeria innocua. The amounts of brine in portions of meat were determined from the concentrations of dye in the tissues, and the numbers of...

Oral cavity rare lesions: 15 years case histories.

ORAL & implantology

Bartuli FN, Luciani F, Cardoni G, Muzzi F, Caddeo F, Ottria L, Arcuri C.
PMID: 23277869
Oral Implantol (Rome). 2011 Jul;4(3):18-22. Epub 2012 Apr 15.

OBJECTIVES.: Oral cavity rare diseases include a various group of uncommon morbid conditions. For this reason they are often called "orphan diseases", as they are not interesting for research and the description of their natural history is not easy....

Expression of β-adrenergic receptors in pediatric malignant brain tumors.

Oncology letters

Sardi I, Giunti L, Bresci C, Buccoliero AM, Degl'innocenti D, Cardellicchio S, Baroni G, Castiglione F, Ros MD, Fiorini P, Giglio S, Genitori L, Aricò M, Filippi L.
PMID: 23255924
Oncol Lett. 2013 Jan;5(1):221-225. doi: 10.3892/ol.2012.989. Epub 2012 Oct 23.

β-adrenergic receptors (β-ARs) are G protein-coupled receptors that activate signal transduction pathways involved in angiogenesis, resulting in enhanced tumor vascularization and more aggressive growth. In this study, we evaluated the expression of β-ARs in a population of 12 children...

Showing 1 to 12 of 214 entries