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Reductive activation of E. coli respiratory nitrate reductase.

Biochimica et biophysica acta

Ceccaldi P, Rendon J, Léger C, Toci R, Guigliarelli B, Magalon A, Grimaldi S, Fourmond V.
PMID: 26073890
Biochim Biophys Acta. 2015 Oct;1847(10):1055-63. doi: 10.1016/j.bbabio.2015.06.007. Epub 2015 Jun 11.

Over the past decades, a number of authors have reported the presence of inactive species in as-prepared samples of members of the Mo/W-bisPGD enzyme family. This greatly complicated the spectroscopic studies of these enzymes, since it is impossible to...

Pregnancy and vascular liver disease.

Journal of clinical and experimental hepatology

Bissonnette J, Durand F, de Raucourt E, Ceccaldi PF, Plessier A, Valla D, Rautou PE.
PMID: 25941432
J Clin Exp Hepatol. 2015 Mar;5(1):41-50. doi: 10.1016/j.jceh.2014.12.007. Epub 2015 Jan 06.

Vascular disorders of the liver frequently affect women of childbearing age. Pregnancy and the postpartum are prothrombotic states. Pregnancy seems to be a trigger for Budd-Chiari syndrome in patients with an underlying prothrombotic disorder. Whether pregnancy is a risk...

Recommendations for the use of Serious Games in people with Alzheimer's Disease, related disorders and frailty.

Frontiers in aging neuroscience

Robert PH, König A, Amieva H, Andrieu S, Bremond F, Bullock R, Ceccaldi M, Dubois B, Gauthier S, Kenigsberg PA, Nave S, Orgogozo JM, Piano J, Benoit M, Touchon J, Vellas B, Yesavage J, Manera V.
PMID: 24715864
Front Aging Neurosci. 2014 Mar 24;6:54. doi: 10.3389/fnagi.2014.00054. eCollection 2014.

Alzheimer's disease and other related disorders (ADRD) represent a major challenge for health care systems within the aging population. It is therefore important to develop better instruments to assess the disease severity and progression, as well as to improve...

Functional role of p-glycoprotein and binding protein effect on the placental transfer of lopinavir/ritonavir in the ex vivo human perfusion model.

Obstetrics and gynecology international

Ceccaldi PF, Gavard L, Mandelbrot L, Rey E, Farinotti R, Treluyer JM, Gil S.
PMID: 19960055
Obstet Gynecol Int. 2009;2009:726593. doi: 10.1155/2009/726593. Epub 2009 May 18.

Aims. To study the influence of P-glycoprotein (P-glycoprotein, ABCB1, MDR1) function on placental transfer of lopinavir with ritonavir at different albumin concentrations. Methods. Cotyledons were perfused with lopinavir, ritonavir, and the internal control antipyrin, at various albumin concentrations (10,...

Pure progressive amnesia: An atypical amnestic syndrome?.

Cognitive neuropsychology

Barbeau EJ, Didic M, Felician O, Tramoni E, Guedj E, Ceccaldi M, Poncet M.
PMID: 21049376
Cogn Neuropsychol. 2006 Dec 01;23(8):1230-47. doi: 10.1080/02643290600893594.

We report on M.S., an 83-year-old patient with isolated pure progressive amnesia. This rare, recently identified, form of amnesia has been described in elderly patients. Neuropathological studies suggest that this syndrome is an atypical clinical presentation of Alzheimer's disease....

Editorial: Facing up to the complexity of neuro degenerative disorders in order to deal with them more effectively.

Current opinion in neurology

Ceccaldi M.
PMID: 30694924
Curr Opin Neurol. 2019 Apr;32(2):253-254. doi: 10.1097/WCO.0000000000000670.

No abstract available.

Mother-to-Child Transmission of Arboviruses during Breastfeeding: From Epidemiology to Cellular Mechanisms.

Viruses

Desgraupes S, Hubert M, Gessain A, Ceccaldi PE, Vidy A.
PMID: 34372518
Viruses. 2021 Jul 07;13(7). doi: 10.3390/v13071312.

Most viruses use several entry sites and modes of transmission to infect their host (parenteral, sexual, respiratory, oro-fecal, transplacental, transcutaneous, etc.). Some of them are known to be essentially transmitted via arthropod bites (mosquitoes, ticks, phlebotomes, sandflies, etc.), and...

A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.

Nature cancer

Zhou J, Gelot C, Pantelidou C, Li A, Yücel H, Davis RE, Farkkila A, Kochupurakkal B, Syed A, Shapiro GI, Tainer JA, Blagg BSJ, Ceccaldi R, D'Andrea AD.
PMID: 34179826
Nat Cancer. 2021 Jun;2(6):598-610. doi: 10.1038/s43018-021-00203-x. Epub 2021 Jun 17.

DNA polymerase theta (POLθ) is synthetic lethal with Homologous Recombination (HR) deficiency and thus a candidate target for HR-deficient cancers. Through high-throughput small molecule screens we identified the antibiotic Novobiocin (NVB) as a specific POLθ inhibitor that selectively kills...

Evidence That Zika Virus Is Transmitted by Breastfeeding to Newborn A129 (.

Frontiers in microbiology

Hubert M, Jeannin P, Burlaud-Gaillard J, Roingeard P, Gessain A, Ceccaldi PE, Vidy A.
PMID: 33193119
Front Microbiol. 2020 Oct 22;11:524678. doi: 10.3389/fmicb.2020.524678. eCollection 2020.

Zika virus (ZIKV) belongs to the

Association of Placental Mesenchymal Dysplasia With a Live Female Fetus and Complete Hydatidiform Mole: Report of a Challenging Case Confirmed by Molecular Genotyping Analysis.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

Hamard A, Heitzmann A, Ceccaldi C, Descriaud C, Mauduit C, Gaillot-Durand L, Hajri T, Massardier J, Vinas R, Allias F.
PMID: 33811206
Int J Gynecol Pathol. 2021 Apr 01; doi: 10.1097/PGP.0000000000000786. Epub 2021 Apr 01.

Placental mesenchymal dysplasia (PMD) and complete hydatidiform mole (CHM) with a coexisting fetus are 2 rare placental abnormalities characterized by lacunar placenta and presence of an embryo on ultrasound examination. We report the case of a 34-yr-old woman referred...

An Emotional Agent for Moral Impairment Rehabilitation in TBI Patients.

Frontiers in psychology

Ceccaldi E, Damiano R, Battaglino C, Galetto V, Zettin M.
PMID: 32695038
Front Psychol. 2020 Jun 30;11:1102. doi: 10.3389/fpsyg.2020.01102. eCollection 2020.

The ability to identify the emotions of others is a key component of what is known as social cognition. Narratives exploit this mechanism to create an emotional bond with the characters and to maintain the engagement of the audience...

Step-by-step development and evaluation of a 3D printed home-made low-cost pediatric tracheobronchial tree for foreign body aspiration extractions.

International journal of pediatric otorhinolaryngology

Chebib E, Lemarteleur V, Azalé M, Deneufbourg L, Ceccaldi PF, Teissier N.
PMID: 35026720
Int J Pediatr Otorhinolaryngol. 2022 Jan 07;153:111040. doi: 10.1016/j.ijporl.2022.111040. Epub 2022 Jan 07.

OBJECTIVES: The management of foreign body aspirations (FBA) is dreaded by pediatric physicians due to the high risk of respiratory distress and a potential fatal outcome, favored by a lack of experience of young specialists. Furthermore, there has been...

Showing 1 to 12 of 50 entries