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Showing 1 to 12 of 63 entries
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Sudden cardiac death in adults with congenitally corrected transposition of the great arteries.

Open heart

McCombe A, Touma F, Jackson D, Canniffe C, Choudhary P, Pressley L, Tanous D, Robinson PJ, Celermajer D.
PMID: 27493760
Open Heart. 2016 Jul 11;3(2):e000407. doi: 10.1136/openhrt-2016-000407. eCollection 2016.

BACKGROUND: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart disease. There have been only few reports of sudden cardiac death (SCD) in patients with ccTGA and reasonable ventricular function.METHODS: A retrospective review of the...

Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study.

Open heart

Arnott C, Skilton MR, Ruohonen S, Juonala M, Viikari JS, Kähönen M, Lehtimäki T, Laitinen T, Celermajer DS, Raitakari OT.
PMID: 26339495
Open Heart. 2015 Aug 28;2(1):e000265. doi: 10.1136/openhrt-2015-000265. eCollection 2015.

BACKGROUND AND OBJECTIVES: Impaired fetal growth is associated with increased cardiovascular morbidity and mortality in adulthood. We sought to determine whether adults born with intrauterine growth restriction have primary maladaptive changes in cardiac structure.METHODS: Study participants were adults (34-49...

Survival outcomes in severe congenital versus non-congenital pulmonary hypertension.

Heart Asia

Arnott C, Boehm C, Lau E, Celermajer DS.
PMID: 27326222
Heart Asia. 2016 Jan 19;8(1):3-7. doi: 10.1136/heartasia-2015-010702. eCollection 2016.

OBJECTIVE: Since 2006, our institution has cared for 70 patients with pulmonary arterial hypertension (PAH) and severe right ventricular (RV) hypertension; 44 with congenital heart disease (CHD) had Eisenmenger syndrome (ES) and 26 had PAH without CHD. We sought...

The role of cardiac MRI in the diagnosis and management of sinus venosus atrial septal defect.

Annals of pediatric cardiology

Ganigara M, Tanous D, Celermajer D, Puranik R.
PMID: 24987269
Ann Pediatr Cardiol. 2014 May;7(2):160-2. doi: 10.4103/0974-2069.132509.

Sinus venosus atrial septal defects (SV-ASDs) are inter-atrial communications caused by a deficiency of the common wall between the superior or inferior vena cava and the right-sided pulmonary veins. The diagnosis can be challenging, especially in adults with delayed...

The Effect of Nitric Oxide Inhibition in Spinal Cord Injured Humans with and without Preserved Sympathetic Control of the Vasculature.

Frontiers in neuroscience

Brown R, Celermajer D, Macefield V, Sander M.
PMID: 27013957
Front Neurosci. 2016 Mar 10;10:95. doi: 10.3389/fnins.2016.00095. eCollection 2016.

UNLABELLED: Systemic pharmacological inhibition of nitric oxide (NO) causes a hypertensive response, which has been attributed both to inhibition of peripheral NO-mediated vasodilatation and to inhibition of central nervous NO-production leading to a later onset sympathetic vasoconstriction. In the...

Optical coherence tomography for serial in vivo imaging of aortic plaque in the rabbit: a preliminary experience.

Open heart

Fulcher J, Patel S, Nicholls SJ, Bao S, Celermajer D.
PMID: 26468403
Open Heart. 2015 Oct 08;2(1):e000314. doi: 10.1136/openhrt-2015-000314. eCollection 2015.

BACKGROUND: In this pilot feasibility study, we aimed to establish a reproducible means of performing serial optical coherence tomography (OCT) procedures in the abdominal aorta of the cholesterol-fed rabbit.METHODS: Eight cholesterol-fed New Zealand White rabbits were assigned to abdominal...

Nitric oxide does not mediate the vasodilation of early human pregnancy.

Heart, lung & circulation

Langenfeld MR, Simmons LA, McCrohon JA, Raitakari OT, Lattimore JD, Hennessy A, Celermajer DS.
PMID: 16352123
Heart Lung Circ. 2003;12(3):142-8. doi: 10.1046/j.1444-2892.2003.00206.x.

BACKGROUND: In early pregnancy, a substantial drop in arterial blood pressure occurs, that might be attributed to enhanced vascular nitric oxide synthesis. We investigated whether nitric oxide mediates the vasodilation that occurs in early human pregnancy.METHODS: Resting and stimulated...

Myocardial tissue velocities in the normal left and right ventricle: relationships and predictors.

Heart, lung & circulation

Greaves K, Puranik R, O'Leary JJ, Celermajer DS.
PMID: 16352219
Heart Lung Circ. 2004 Dec;13(4):367-73. doi: 10.1016/j.hlc.2004.09.009.

OBJECTIVES: (1) To document, using tissue Doppler echocardiography (TDE), the regional variations in myocardial velocities (MV) in the left and right ventricles (LV and RV) in healthy young adults. (2) To determine the factors predicting MV.BACKGROUND: The pattern of...

Corrigendum to: "The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation" [Atherosclerosis. 2018 Feb;269:262-271].

Atherosclerosis

Martínez GJ, Celermajer DS, Patel S.
PMID: 29655831
Atherosclerosis. 2018 Jun;273:157. doi: 10.1016/j.atherosclerosis.2018.03.043. Epub 2018 Apr 11.

No abstract available.

Clarion call for histopathological clot analysis in "cryptogenic" ischemic stroke: implications for diagnosis and treatment.

Annals of clinical and translational neurology

Bhaskar S, Cordato D, Cappelen-Smith C, Cheung A, Ledingham D, Celermajer D, Levi C.
PMID: 29296623
Ann Clin Transl Neurol. 2017 Nov 12;4(12):926-930. doi: 10.1002/acn3.500. eCollection 2017 Dec.

Diagnosis, treatment, and secondary management of cryptogenic stroke patients pose a formidable challenge. The scenario is further complicated in patients with native and prosthetic valvular heart disease. We present a case study of a 36-year-old man who received intravenous...

The common carotid artery provides significant pressure wave dampening in the young adult sheep.

International journal of cardiology. Heart & vasculature

James NL, Milijasevic Z, Ujhazy A, Edwards G, Jermyn K, Mynard JP, Celermajer DS.
PMID: 31321284
Int J Cardiol Heart Vasc. 2019 Mar 22;23:100343. doi: 10.1016/j.ijcha.2019.03.003. eCollection 2019 Jun.

BACKGROUND: It has been established that the central elastic arteries of the mammalian circulation dampen the high pulse pressure emanating from the left ventricle, so that the pulsations in distal arterioles, such as in the cerebral circulation, are of...

Prevalence and Outcomes of Low-Gradient Severe Aortic Stenosis-From the National Echo Database of Australia.

Journal of the American Heart Association

Snir AD, Ng MK, Strange G, Playford D, Stewart S, Celermajer DS.
PMID: 34719256
J Am Heart Assoc. 2021 Nov 16;10(22):e021126. doi: 10.1161/JAHA.121.021126. Epub 2021 Oct 30.

Background The prevalence and outcomes of the different subtypes of severe low-gradient aortic stenosis (AS) in routine clinical cardiology practice have not been well characterized. Methods and Results Data were derived from the National Echocardiography Database of Australia. Of...

Showing 1 to 12 of 63 entries