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Showing 1 to 12 of 17 entries
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Genesis of myocardial repair with cardiac progenitor cells and tissue engineering.

Heart Asia

Sim EK, Haider HKh, Lila N, Schussler O, Chachques JC, Ye L.
PMID: 27325955
Heart Asia. 2010 Sep 18;2(1):109-11. doi: 10.1136/ha.2009.001651. eCollection 2010.

BACKGROUND: There is mounting evidence to suggest that the heart has regenerative potential in the event of myocardial injury. Recent studies have shown that a resident population of cardiac progenitor cells (CPCs) in the heart contains both vasculogenic and...

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Sim EK, Haider HKh, Lila N, et al. Genesis of myocardial repair with cardiac progenitor cells and tissue engineering. Heart Asia. 2010;2(1):109-11doi: 10.1136/ha.2009.001651.
Sim, E. K., Haider, H. K. h., Lila, N., Schussler, O., Chachques, J. C., & Ye, L. (2010). Genesis of myocardial repair with cardiac progenitor cells and tissue engineering. Heart Asia, 2(1), 109-11. https://doi.org/10.1136/ha.2009.001651
Sim, Eugene K W, et al. "Genesis of myocardial repair with cardiac progenitor cells and tissue engineering." Heart Asia vol. 2,1 (2010): 109-11. doi: https://doi.org/10.1136/ha.2009.001651
Sim EK, Haider HKh, Lila N, Schussler O, Chachques JC, Ye L. Genesis of myocardial repair with cardiac progenitor cells and tissue engineering. Heart Asia. 2010 Sep 18;2(1):109-11. doi: 10.1136/ha.2009.001651. eCollection 2010. PMID: 27325955; PMCID: PMC4898522.
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Development of bioartificial myocardium using stem cells and nanobiotechnology templates.

Cardiology research and practice

Chachques JC.
PMID: 21253535
Cardiol Res Pract. 2010 Dec 29;2011:806795. doi: 10.4061/2011/806795.

Cell-based regenerative therapy is undergoing experimental and clinical trials in cardiology, in order to limit the consequences of decreased contractile function and compliance of damaged ventricles following myocardial infarction. Over 1000 patients have been treated worldwide with cell-based procedures...

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Chachques JC. Development of bioartificial myocardium using stem cells and nanobiotechnology templates. Cardiol Res Pract. 2010;2011:806795doi: 10.4061/2011/806795.
Chachques, J. C. (2010). Development of bioartificial myocardium using stem cells and nanobiotechnology templates. Cardiology research and practice, 2011806795. https://doi.org/10.4061/2011/806795
Chachques, Juan Carlos. "Development of bioartificial myocardium using stem cells and nanobiotechnology templates." Cardiology research and practice vol. 2011 (2010): 806795. doi: https://doi.org/10.4061/2011/806795
Chachques JC. Development of bioartificial myocardium using stem cells and nanobiotechnology templates. Cardiol Res Pract. 2010 Dec 29;2011:806795. doi: 10.4061/2011/806795. PMID: 21253535; PMCID: PMC3021848.
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Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation.

Biomimetics (Basel, Switzerland)

Nappi F, Nenna A, Lemmo F, Chello M, Chachques JC, Acar C, Larobina D.
PMID: 32756408
Biomimetics (Basel). 2020 Aug 03;5(3). doi: 10.3390/biomimetics5030037.

Ross operation might be a valid option for congenital and acquired left ventricular outflow tract disease in selected cases. As the pulmonary autograft is a living substitute for the aortic root that bioinspired the Ross operation, we have created...

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Nappi F, Nenna A, Lemmo F, et al. Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation. Biomimetics (Basel). 2020;5(3)doi: 10.3390/biomimetics5030037.
Nappi, F., Nenna, A., Lemmo, F., Chello, M., Chachques, J. C., Acar, C., & Larobina, D. (2020). Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation. Biomimetics (Basel, Switzerland), 5(3), . https://doi.org/10.3390/biomimetics5030037
Nappi, Francesco, et al. "Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation." Biomimetics (Basel, Switzerland) vol. 5,3 (2020). doi: https://doi.org/10.3390/biomimetics5030037
Nappi F, Nenna A, Lemmo F, Chello M, Chachques JC, Acar C, Larobina D. Finite Element Analysis Investigate Pulmonary Autograft Root and Leaflet Stresses to Understand Late Durability of Ross Operation. Biomimetics (Basel). 2020 Aug 03;5(3). doi: 10.3390/biomimetics5030037. PMID: 32756408; PMCID: PMC7559879.
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Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction.

Journal of cardiovascular translational research

Schussler O, Chachques JC, Alifano M, Lecarpentier Y.
PMID: 34342855
J Cardiovasc Transl Res. 2021 Aug 03; doi: 10.1007/s12265-021-10154-4. Epub 2021 Aug 03.

Cardiac cells interact with the extracellular matrix (ECM) proteins through integrin mechanoreceptors that control many cellular events such as cell survival, apoptosis, differentiation, migration, and proliferation. Integrins play a crucial role in cardiac development as well as in cardiac...

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Schussler O, Chachques JC, Alifano M, et al. Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction. J Cardiovasc Transl Res. 2021;doi: 10.1007/s12265-021-10154-4.
Schussler, O., Chachques, J. C., Alifano, M., & Lecarpentier, Y. (2021). Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction. Journal of cardiovascular translational research, . https://doi.org/10.1007/s12265-021-10154-4
Schussler, Olivier, et al. "Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction." Journal of cardiovascular translational research vol. (2021). doi: https://doi.org/10.1007/s12265-021-10154-4
Schussler O, Chachques JC, Alifano M, Lecarpentier Y. Key Roles of RGD-Recognizing Integrins During Cardiac Development, on Cardiac Cells, and After Myocardial Infarction. J Cardiovasc Transl Res. 2021 Aug 03; doi: 10.1007/s12265-021-10154-4. Epub 2021 Aug 03. PMID: 34342855.
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Possible Treatment of Myocardial Infarct Based on Tissue Engineering Using a Cellularized Solid Collagen Scaffold Functionalized with Arg-Glyc-Asp (RGD) Peptide.

International journal of molecular sciences

Schussler O, Falcoz PE, Chachques JC, Alifano M, Lecarpentier Y.
PMID: 34830447
Int J Mol Sci. 2021 Nov 22;22(22). doi: 10.3390/ijms222212563.

Currently, the clinical impact of cell therapy after a myocardial infarction (MI) is limited by low cell engraftment due to low cell retention, cell death in inflammatory and poor angiogenic infarcted areas, secondary migration. Cells interact with their microenvironment...

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Schussler O, Falcoz PE, Chachques JC, et al. Possible Treatment of Myocardial Infarct Based on Tissue Engineering Using a Cellularized Solid Collagen Scaffold Functionalized with Arg-Glyc-Asp (RGD) Peptide. Int J Mol Sci. 2021;22(22)doi: 10.3390/ijms222212563.
Schussler, O., Falcoz, P. E., Chachques, J. C., Alifano, M., & Lecarpentier, Y. (2021). Possible Treatment of Myocardial Infarct Based on Tissue Engineering Using a Cellularized Solid Collagen Scaffold Functionalized with Arg-Glyc-Asp (RGD) Peptide. International journal of molecular sciences, 22(22), . https://doi.org/10.3390/ijms222212563
Schussler, Olivier, et al. "Possible Treatment of Myocardial Infarct Based on Tissue Engineering Using a Cellularized Solid Collagen Scaffold Functionalized with Arg-Glyc-Asp (RGD) Peptide." International journal of molecular sciences vol. 22,22 (2021). doi: https://doi.org/10.3390/ijms222212563
Schussler O, Falcoz PE, Chachques JC, Alifano M, Lecarpentier Y. Possible Treatment of Myocardial Infarct Based on Tissue Engineering Using a Cellularized Solid Collagen Scaffold Functionalized with Arg-Glyc-Asp (RGD) Peptide. Int J Mol Sci. 2021 Nov 22;22(22). doi: 10.3390/ijms222212563. PMID: 34830447; PMCID: PMC8620820.
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Mesenchymal stem cell therapy in nonhematopoietic diseases.

Stem cells international

de Carvalho KA, Steinhoff G, Chachques JC.
PMID: 25815015
Stem Cells Int. 2015;2015:676903. doi: 10.1155/2015/676903. Epub 2015 Mar 01.

No abstract available.

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de Carvalho KA, Steinhoff G, Chachques JC. Mesenchymal stem cell therapy in nonhematopoietic diseases. Stem Cells Int. 2015;2015:676903doi: 10.1155/2015/676903.
de Carvalho, K. A., Steinhoff, G., & Chachques, J. C. (2015). Mesenchymal stem cell therapy in nonhematopoietic diseases. Stem cells international, 2015676903. https://doi.org/10.1155/2015/676903
de Carvalho, Katherine Athayde Teixeira, et al. "Mesenchymal stem cell therapy in nonhematopoietic diseases." Stem cells international vol. 2015 (2015): 676903. doi: https://doi.org/10.1155/2015/676903
de Carvalho KA, Steinhoff G, Chachques JC. Mesenchymal stem cell therapy in nonhematopoietic diseases. Stem Cells Int. 2015;2015:676903. doi: 10.1155/2015/676903. Epub 2015 Mar 01. PMID: 25815015; PMCID: PMC4359802.
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Engineered 3D bioimplants using elastomeric scaffold, self-assembling peptide hydrogel, and adipose tissue-derived progenitor cells for cardiac regeneration.

American journal of translational research

Soler-Botija C, Bagó JR, Llucià-Valldeperas A, Vallés-Lluch A, Castells-Sala C, Martínez-Ramos C, Fernández-Muiños T, Chachques JC, Pradas MM, Semino CE, Bayes-Genis A.
PMID: 24936221
Am J Transl Res. 2014 May 15;6(3):291-301. eCollection 2014.

Contractile restoration of myocardial scars remains a challenge with important clinical implications. Here, a combination of porous elastomeric membrane, peptide hydrogel, and subcutaneous adipose tissue-derived progenitor cells (subATDPCs) was designed and evaluated as a bioimplant for cardiac regeneration in...

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Soler-Botija C, Bagó JR, Llucià-Valldeperas A, et al. Engineered 3D bioimplants using elastomeric scaffold, self-assembling peptide hydrogel, and adipose tissue-derived progenitor cells for cardiac regeneration. Am J Transl Res. 2014;6(3):291-301
Soler-Botija, C., Bagó, J. R., Llucià-Valldeperas, A., Vallés-Lluch, A., Castells-Sala, C., Martínez-Ramos, C., Fernández-Muiños, T., Chachques, J. C., Pradas, M. M., Semino, C. E., & Bayes-Genis, A. (2014). Engineered 3D bioimplants using elastomeric scaffold, self-assembling peptide hydrogel, and adipose tissue-derived progenitor cells for cardiac regeneration. American journal of translational research, 6(3), 291-301.
Soler-Botija, Carolina, et al. "Engineered 3D bioimplants using elastomeric scaffold, self-assembling peptide hydrogel, and adipose tissue-derived progenitor cells for cardiac regeneration." American journal of translational research vol. 6,3 (2014): 291-301.
Soler-Botija C, Bagó JR, Llucià-Valldeperas A, Vallés-Lluch A, Castells-Sala C, Martínez-Ramos C, Fernández-Muiños T, Chachques JC, Pradas MM, Semino CE, Bayes-Genis A. Engineered 3D bioimplants using elastomeric scaffold, self-assembling peptide hydrogel, and adipose tissue-derived progenitor cells for cardiac regeneration. Am J Transl Res. 2014 May 15;6(3):291-301. eCollection 2014. PMID: 24936221; PMCID: PMC4058310.
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Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction.

ISRN cardiology

Shafy A, Molinié V, Cortes-Morichetti M, Hupertan V, Lila N, Chachques JC.
PMID: 22462024
ISRN Cardiol. 2012;2012:326809. doi: 10.5402/2012/326809. Epub 2012 Mar 14.

Adenosine and inosine are both key intracellular energy substrates for nucleotide synthesis by salvage pathways, especially during ischemic stress conditions. Additionally they both possess cell protective and cell repair properties. The objective of this study is to detect potential...

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Shafy A, Molinié V, Cortes-Morichetti M, et al. Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction. ISRN Cardiol. 2012;2012:326809doi: 10.5402/2012/326809.
Shafy, A., Molinié, V., Cortes-Morichetti, M., Hupertan, V., Lila, N., & Chachques, J. C. (2012). Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction. ISRN cardiology, 2012326809. https://doi.org/10.5402/2012/326809
Shafy, Abdel, et al. "Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction." ISRN cardiology vol. 2012 (2012): 326809. doi: https://doi.org/10.5402/2012/326809
Shafy A, Molinié V, Cortes-Morichetti M, Hupertan V, Lila N, Chachques JC. Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction. ISRN Cardiol. 2012;2012:326809. doi: 10.5402/2012/326809. Epub 2012 Mar 14. PMID: 22462024; PMCID: PMC3312546.
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Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells.

Heart international

Haneef K, Lila N, Benadda S, Legrand F, Carpentier A, Chachques JC.
PMID: 23185681
Heart Int. 2012 Jun 05;7(2):e14. doi: 10.4081/hi.2012.e14. Epub 2012 Sep 18.

Electrostimulation (ES) can be defined as a safe physical method to induce stem cell differentiation. The aim of this study is to evaluate the effectiveness of ES on bone marrow mesenchymal stem cells (BMSCs) seeded in collagen scaffolds in...

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Haneef K, Lila N, Benadda S, et al. Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells. Heart Int. 2012;7(2):e14doi: 10.4081/hi.2012.e14.
Haneef, K., Lila, N., Benadda, S., Legrand, F., Carpentier, A., & Chachques, J. C. (2012). Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells. Heart international, 7(2), e14. https://doi.org/10.4081/hi.2012.e14
Haneef, Kanwal, et al. "Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells." Heart international vol. 7,2 (2012): e14. doi: https://doi.org/10.4081/hi.2012.e14
Haneef K, Lila N, Benadda S, Legrand F, Carpentier A, Chachques JC. Development of bioartificial myocardium by electrostimulation of 3D collagen scaffolds seeded with stem cells. Heart Int. 2012 Jun 05;7(2):e14. doi: 10.4081/hi.2012.e14. Epub 2012 Sep 18. PMID: 23185681; PMCID: PMC3504306.
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Preconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1α Promotes Cytoprotective Effects against Oxidative and Anoxic Stress.

International journal of stem cells

Elmadbouh I, Haider HKh, Ashraf M, Chachques JC.
PMID: 24298334
Int J Stem Cells. 2011 Jun;4(1):50-60. doi: 10.15283/ijsc.2011.4.1.50.

BACKGROUND AND OBJECTIVES: The incidence of human autologous transplanted skeletal myoblast (SkM) cell death in ischemic myocardium was higher in the first few days after cell therapy. We proposed that human SkM treated by human stromal cell-derived factor (SDF-1α)...

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Elmadbouh I, Haider HKh, Ashraf M, et al. Preconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1α Promotes Cytoprotective Effects against Oxidative and Anoxic Stress. Int J Stem Cells. 2011;4(1):50-60doi: 10.15283/ijsc.2011.4.1.50.
Elmadbouh, I., Haider, H. K. h., Ashraf, M., & Chachques, J. C. (2011). Preconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1α Promotes Cytoprotective Effects against Oxidative and Anoxic Stress. International journal of stem cells, 4(1), 50-60. https://doi.org/10.15283/ijsc.2011.4.1.50
Elmadbouh, Ibrahim, et al. "Preconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1α Promotes Cytoprotective Effects against Oxidative and Anoxic Stress." International journal of stem cells vol. 4,1 (2011): 50-60. doi: https://doi.org/10.15283/ijsc.2011.4.1.50
Elmadbouh I, Haider HKh, Ashraf M, Chachques JC. Preconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1α Promotes Cytoprotective Effects against Oxidative and Anoxic Stress. Int J Stem Cells. 2011 Jun;4(1):50-60. doi: 10.15283/ijsc.2011.4.1.50. PMID: 24298334; PMCID: PMC3840971.
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Abdominal aortic aneurysmectomy in renal transplant patients.

Texas Heart Institute journal

Jebara VA, Fabiani JN, Moulonguet-Deloris L, Acar C, Debauchez M, Chachques JC, Glotz D, Duboust A, Langanay T, Carpentier A.
PMID: 15227179
Tex Heart Inst J. 1990;17(3):240-4.

Because renal transplantation is allowing an increased number of patients to survive for prolonged periods, abdominal aortic aneurysms can be expected to occur with growing frequency in these patients. Surgical management of such cases involves the provision of allograft...

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Jebara VA, Fabiani JN, Moulonguet-Deloris L, et al. Abdominal aortic aneurysmectomy in renal transplant patients. Tex Heart Inst J. 1990;17(3):240-4
Jebara, V. A., Fabiani, J. N., Moulonguet-Deloris, L., Acar, C., Debauchez, M., Chachques, J. C., Glotz, D., Duboust, A., Langanay, T., & Carpentier, A. (1990). Abdominal aortic aneurysmectomy in renal transplant patients. Texas Heart Institute journal, 17(3), 240-4.
Jebara, V A, et al. "Abdominal aortic aneurysmectomy in renal transplant patients." Texas Heart Institute journal vol. 17,3 (1990): 240-4.
Jebara VA, Fabiani JN, Moulonguet-Deloris L, Acar C, Debauchez M, Chachques JC, Glotz D, Duboust A, Langanay T, Carpentier A. Abdominal aortic aneurysmectomy in renal transplant patients. Tex Heart Inst J. 1990;17(3):240-4. PMID: 15227179; PMCID: PMC324925.
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Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?.

Journal of clinical medicine

Gardin C, Ferroni L, Chachques JC, Zavan B.
PMID: 32858940
J Clin Med. 2020 Aug 26;9(9). doi: 10.3390/jcm9092762.

Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severe form of the disease is often associated with acute respiratory distress...

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Gardin C, Ferroni L, Chachques JC, et al. Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?. J Clin Med. 2020;9(9)doi: 10.3390/jcm9092762.
Gardin, C., Ferroni, L., Chachques, J. C., & Zavan, B. (2020). Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?. Journal of clinical medicine, 9(9), . https://doi.org/10.3390/jcm9092762
Gardin, Chiara, et al. "Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?." Journal of clinical medicine vol. 9,9 (2020). doi: https://doi.org/10.3390/jcm9092762
Gardin C, Ferroni L, Chachques JC, Zavan B. Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?. J Clin Med. 2020 Aug 26;9(9). doi: 10.3390/jcm9092762. PMID: 32858940; PMCID: PMC7565764.
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Showing 1 to 12 of 17 entries