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Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization.

Polymer chemistry

Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN.
PMID: 29093759
Polym Chem. 2016 Dec 28;7(48):7514-7521. doi: 10.1039/C6PY01615D. Epub 2016 Nov 14.

The plasma membrane is a major obstacle in the development and use of biomacromolecules for intracellular therapeutic applications. Protein transduction domains (PTDs) have been used to overcome this barrier, but often require covalent conjugation to their cargo and can...

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Backlund CM, Sgolastra F, Otter R, et al. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polym Chem. 2016;7(48):7514-7521doi: 10.1039/C6PY01615D.
Backlund, C. M., Sgolastra, F., Otter, R., Minter, L., Takeuchi, T., Futaki, S., & Tew, G. N. (2016). Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polymer chemistry, 7(48), 7514-7521. https://doi.org/10.1039/C6PY01615D
Backlund, Coralie M, et al. "Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization." Polymer chemistry vol. 7,48 (2016): 7514-7521. doi: https://doi.org/10.1039/C6PY01615D
Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polym Chem. 2016 Dec 28;7(48):7514-7521. doi: 10.1039/C6PY01615D. Epub 2016 Nov 14. PMID: 29093759; PMCID: PMC5661863.
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Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80.

Inorganic chemistry

Stevenson S, Rose CB, Maslenikova JS, Villarreal JR, Mackey MA, Mercado BQ, Chen K, Olmstead MM, Balch AL.
PMID: 23214426
Inorg Chem. 2012 Dec 17;51(24):13096-102. doi: 10.1021/ic300888e. Epub 2012 Dec 06.

The successful preparation and isolation of the mixed-metal endohedral fullerene, LaSc(2)N@I(h)-C(80), and its structural characterization by single-crystal X-ray diffraction are reported. Results from chemically adjusting plasma temperature, energy, and reactivity (CAPTEAR) experiments indicate that a 10 wt % addition...

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Stevenson S, Rose CB, Maslenikova JS, et al. Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorg Chem. 2012;51(24):13096-102doi: 10.1021/ic300888e.
Stevenson, S., Rose, C. B., Maslenikova, J. S., Villarreal, J. R., Mackey, M. A., Mercado, B. Q., Chen, K., Olmstead, M. M., & Balch, A. L. (2012). Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorganic chemistry, 51(24), 13096-102. https://doi.org/10.1021/ic300888e
Stevenson, Steven, et al. "Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80." Inorganic chemistry vol. 51,24 (2012): 13096-102. doi: https://doi.org/10.1021/ic300888e
Stevenson S, Rose CB, Maslenikova JS, Villarreal JR, Mackey MA, Mercado BQ, Chen K, Olmstead MM, Balch AL. Selective synthesis, isolation, and crystallographic characterization of LaSc2N@I(h)-C80. Inorg Chem. 2012 Dec 17;51(24):13096-102. doi: 10.1021/ic300888e. Epub 2012 Dec 06. PMID: 23214426.
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Association Between Newborn Metabolic Profiles and Pediatric Kidney Disease.

Kidney international reports

Sood MM, Murphy MSQ, Hawken S, Wong CA, Potter BK, Burns KD, Tsampalieros A, Atkinson KM, Chakraborty P, Wilson K.
PMID: 29854978
Kidney Int Rep. 2018 Feb 10;3(3):691-700. doi: 10.1016/j.ekir.2018.02.001. eCollection 2018 May.

INTRODUCTION: Metabolomics offers considerable promise in early disease detection. We set out to test the hypothesis that routine newborn metabolic profiles at birth, obtained through screening for inborn errors of metabolism, would be associated with kidney disease and add...

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Sood MM, Murphy MSQ, Hawken S, et al. Association Between Newborn Metabolic Profiles and Pediatric Kidney Disease. Kidney Int Rep. 2018;3(3):691-700doi: 10.1016/j.ekir.2018.02.001.
Sood, M. M., Murphy, M. S. Q., Hawken, S., Wong, C. A., Potter, B. K., Burns, K. D., Tsampalieros, A., Atkinson, K. M., Chakraborty, P., & Wilson, K. (2018). Association Between Newborn Metabolic Profiles and Pediatric Kidney Disease. Kidney international reports, 3(3), 691-700. https://doi.org/10.1016/j.ekir.2018.02.001
Sood, Manish M, et al. "Association Between Newborn Metabolic Profiles and Pediatric Kidney Disease." Kidney international reports vol. 3,3 (2018): 691-700. doi: https://doi.org/10.1016/j.ekir.2018.02.001
Sood MM, Murphy MSQ, Hawken S, Wong CA, Potter BK, Burns KD, Tsampalieros A, Atkinson KM, Chakraborty P, Wilson K. Association Between Newborn Metabolic Profiles and Pediatric Kidney Disease. Kidney Int Rep. 2018 Feb 10;3(3):691-700. doi: 10.1016/j.ekir.2018.02.001. eCollection 2018 May. PMID: 29854978; PMCID: PMC5976820.
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Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography: Reproducibility and Lack of Consensus Impacts on Clinical Decisions.

Aorta (Stamford, Conn.)

Mora CE, Marcus CD, Barbe CM, Ecarnot FB, Long AL.
PMID: 26798757
Aorta (Stamford). 2015 Apr 01;3(2):47-55. doi: 10.12945/j.aorta.2015.14-059. eCollection 2015 Apr.

BACKGROUND: Computed tomography angiography (CTA) is the reference technique for the measurement of native maximum abdominal aortic aneurysm (AAA) diameter when surgery is being considered. However, there is a wide choice available for the methodology of maximum AAA diameter...

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Mora CE, Marcus CD, Barbe CM, et al. Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography: Reproducibility and Lack of Consensus Impacts on Clinical Decisions. Aorta (Stamford). 2015;3(2):47-55doi: 10.12945/j.aorta.2015.14-059.
Mora, C. E., Marcus, C. D., Barbe, C. M., Ecarnot, F. B., & Long, A. L. (2015). Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography: Reproducibility and Lack of Consensus Impacts on Clinical Decisions. Aorta (Stamford, Conn.), 3(2), 47-55. https://doi.org/10.12945/j.aorta.2015.14-059
Mora, Caroline E, et al. "Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography: Reproducibility and Lack of Consensus Impacts on Clinical Decisions." Aorta (Stamford, Conn.) vol. 3,2 (2015): 47-55. doi: https://doi.org/10.12945/j.aorta.2015.14-059
Mora CE, Marcus CD, Barbe CM, Ecarnot FB, Long AL. Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography: Reproducibility and Lack of Consensus Impacts on Clinical Decisions. Aorta (Stamford). 2015 Apr 01;3(2):47-55. doi: 10.12945/j.aorta.2015.14-059. eCollection 2015 Apr. PMID: 26798757; PMCID: PMC4686349.
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L'autophagie sélective au cours des infections virales.

Virologie (Montrouge, France)

Daussy CF, Espert L.
PMID: 32260032
Virologie (Montrouge). 2016 Aug 01;20(4):196-206. doi: 10.1684/vir.2016.0665.

Autophagy is a major catabolic pathway involved in several important cellular functions including homeostasis, development, differentiation and immunity. Consequently, deregulations of this process have been observed in several pathologies. Autophagy leads to the lysosomal degradation of cellular components after...

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Daussy CF, Espert L. Selective autophagy during viral infections. L'autophagie sélective au cours des infections virales. Virologie (Montrouge). 2016;20(4):196-206doi: 10.1684/vir.2016.0665.
Daussy, C. F., & Espert, L. (2016). Selective autophagy during viral infections. L'autophagie sélective au cours des infections virales. Virologie (Montrouge, France), 20(4), 196-206. https://doi.org/10.1684/vir.2016.0665
Daussy, Coralie F, and Espert, Lucile. "Selective autophagy during viral infections." L'autophagie sélective au cours des infections virales. Virologie (Montrouge, France) vol. 20,4 (2016): 196-206. doi: https://doi.org/10.1684/vir.2016.0665
Daussy CF, Espert L. Selective autophagy during viral infections. L'autophagie sélective au cours des infections virales. Virologie (Montrouge). 2016 Aug 01;20(4):196-206. doi: 10.1684/vir.2016.0665. PMID: 32260032.
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Transport of Vitamin C in Cancer.

Antioxidants & redox signaling

Muñoz-Montesino C, Peña E, Roa FJ, Sotomayor K, Escobar E, Rivas CI.
PMID: 33607936
Antioxid Redox Signal. 2021 Jul;35(1):61-74. doi: 10.1089/ars.2020.8166. Epub 2021 Apr 23.

No abstract available.

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Muñoz-Montesino C, Peña E, Roa FJ, et al. Transport of Vitamin C in Cancer. Antioxid Redox Signal. 2021;35(1):61-74doi: 10.1089/ars.2020.8166.
Muñoz-Montesino, C., Peña, E., Roa, F. J., Sotomayor, K., Escobar, E., & Rivas, C. I. (2021). Transport of Vitamin C in Cancer. Antioxidants & redox signaling, 35(1), 61-74. https://doi.org/10.1089/ars.2020.8166
Muñoz-Montesino, Carola, et al. "Transport of Vitamin C in Cancer." Antioxidants & redox signaling vol. 35,1 (2021): 61-74. doi: https://doi.org/10.1089/ars.2020.8166
Muñoz-Montesino C, Peña E, Roa FJ, Sotomayor K, Escobar E, Rivas CI. Transport of Vitamin C in Cancer. Antioxid Redox Signal. 2021 Jul;35(1):61-74. doi: 10.1089/ars.2020.8166. Epub 2021 Apr 23. PMID: 33607936.
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Gonadotropins as novel active partners in vascular diseases: Insight from angiogenic properties and thrombotic potential of endothelial colony-forming cells.

Journal of thrombosis and haemostasis : JTH

Détriché G, Gendron N, Philippe A, Gruest M, Billoir P, Rossi E, Guerin CL, Lokajczyk A, Brabant S, Prié D, Mirault T, Smadja DM.
PMID: 34623025
J Thromb Haemost. 2022 Jan;20(1):230-237. doi: 10.1111/jth.15549. Epub 2021 Oct 29.

BACKGROUND: The impact of estrogen and testosterone on atherosclerotic cardiovascular disease is well known, but the role of the gonadotropins follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL) to some extent remain less studied.OBJECTIVES: To explore the angiogenic...

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Détriché G, Gendron N, Philippe A, et al. Gonadotropins as novel active partners in vascular diseases: Insight from angiogenic properties and thrombotic potential of endothelial colony-forming cells. J Thromb Haemost. 2021;20(1):230-237doi: 10.1111/jth.15549.
Détriché, G., Gendron, N., Philippe, A., Gruest, M., Billoir, P., Rossi, E., Guerin, C. L., Lokajczyk, A., Brabant, S., Prié, D., Mirault, T., & Smadja, D. M. (2022). Gonadotropins as novel active partners in vascular diseases: Insight from angiogenic properties and thrombotic potential of endothelial colony-forming cells. Journal of thrombosis and haemostasis : JTH, 20(1), 230-237. https://doi.org/10.1111/jth.15549
Détriché, Grégoire, et al. "Gonadotropins as novel active partners in vascular diseases: Insight from angiogenic properties and thrombotic potential of endothelial colony-forming cells." Journal of thrombosis and haemostasis : JTH vol. 20,1 (2022): 230-237. doi: https://doi.org/10.1111/jth.15549
Détriché G, Gendron N, Philippe A, Gruest M, Billoir P, Rossi E, Guerin CL, Lokajczyk A, Brabant S, Prié D, Mirault T, Smadja DM. Gonadotropins as novel active partners in vascular diseases: Insight from angiogenic properties and thrombotic potential of endothelial colony-forming cells. J Thromb Haemost. 2022 Jan;20(1):230-237. doi: 10.1111/jth.15549. Epub 2021 Oct 29. PMID: 34623025.
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Endothelial Colony-Forming Cells from Idiopathic Pulmonary Fibrosis Patients Have a High Procoagulant Potential.

Stem cell reviews and reports

Billoir P, Blandinières A, Gendron N, Chocron R, Gunther S, Philippe A, Guerin CL, Israël-Biet D, Smadja DM.
PMID: 32970229
Stem Cell Rev Rep. 2021 Apr;17(2):694-699. doi: 10.1007/s12015-020-10043-4. Epub 2020 Sep 24.

Idiopathic pulmonary fibrosis (IPF) is a severe, progressive and irreversible lung disease constantly associated with a major vascular remodeling process. Endothelial colony-forming cells (ECFCs) are human vasculogenic cells proposed as a cell therapy product or liquid biopsy in vascular...

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Billoir P, Blandinières A, Gendron N, et al. Endothelial Colony-Forming Cells from Idiopathic Pulmonary Fibrosis Patients Have a High Procoagulant Potential. Stem Cell Rev Rep. 2020;17(2):694-699doi: 10.1007/s12015-020-10043-4.
Billoir, P., Blandinières, A., Gendron, N., Chocron, R., Gunther, S., Philippe, A., Guerin, C. L., Israël-Biet, D., & Smadja, D. M. (2021). Endothelial Colony-Forming Cells from Idiopathic Pulmonary Fibrosis Patients Have a High Procoagulant Potential. Stem cell reviews and reports, 17(2), 694-699. https://doi.org/10.1007/s12015-020-10043-4
Billoir, Paul, et al. "Endothelial Colony-Forming Cells from Idiopathic Pulmonary Fibrosis Patients Have a High Procoagulant Potential." Stem cell reviews and reports vol. 17,2 (2021): 694-699. doi: https://doi.org/10.1007/s12015-020-10043-4
Billoir P, Blandinières A, Gendron N, Chocron R, Gunther S, Philippe A, Guerin CL, Israël-Biet D, Smadja DM. Endothelial Colony-Forming Cells from Idiopathic Pulmonary Fibrosis Patients Have a High Procoagulant Potential. Stem Cell Rev Rep. 2021 Apr;17(2):694-699. doi: 10.1007/s12015-020-10043-4. Epub 2020 Sep 24. PMID: 32970229.
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Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam.

Journal of controlled release : official journal of the Controlled Release Society

Chen YC, Moseson DE, Richard CA, Swinney MR, Horava SD, Oucherif KA, Cox AL, Hawkins ED, Li Y, DeNeve DF, Lomeo J, Zhu A, Lyle LT, Munson EJ, Taylor LS, Park K, Yeo Y.
PMID: 34990702
J Control Release. 2022 Jan 03;342:189-200. doi: 10.1016/j.jconrel.2021.12.038. Epub 2022 Jan 03.

For effective resolution of regional subacute inflammation and prevention of biofouling formation, we have developed a polymeric implant that can release meloxicam, a selective cyclooxygenase (COX)-2 inhibitor, in a sustained manner. Meloxicam-loaded polymer matrices were produced by hot-melt extrusion,...

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Chen YC, Moseson DE, Richard CA, et al. Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam. J Control Release. 2022;342:189-200doi: 10.1016/j.jconrel.2021.12.038.
Chen, Y. C., Moseson, D. E., Richard, C. A., Swinney, M. R., Horava, S. D., Oucherif, K. A., Cox, A. L., Hawkins, E. D., Li, Y., DeNeve, D. F., Lomeo, J., Zhu, A., Lyle, L. T., Munson, E. J., Taylor, L. S., Park, K., & Yeo, Y. (2022). Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam. Journal of controlled release : official journal of the Controlled Release Society, 342189-200. https://doi.org/10.1016/j.jconrel.2021.12.038
Chen, Yun-Chu, et al. "Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam." Journal of controlled release : official journal of the Controlled Release Society vol. 342 (2022): 189-200. doi: https://doi.org/10.1016/j.jconrel.2021.12.038
Chen YC, Moseson DE, Richard CA, Swinney MR, Horava SD, Oucherif KA, Cox AL, Hawkins ED, Li Y, DeNeve DF, Lomeo J, Zhu A, Lyle LT, Munson EJ, Taylor LS, Park K, Yeo Y. Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam. J Control Release. 2022 Jan 03;342:189-200. doi: 10.1016/j.jconrel.2021.12.038. Epub 2022 Jan 03. PMID: 34990702.
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Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.

Nature cancer

Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T.
PMID: 34738089
Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30.

Immune evasion is a hallmark of cancer, and therapies that restore immune surveillance have proven highly effective in cancers with high tumor mutation burden (TMB) (e.g., those with microsatellite instability (MSI)). Whether low TMB cancers, which are largely refractory...

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Westcott PMK, Sacks NJ, Schenkel JM, et al. Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer. Nat Cancer. 2021;2(10):1071-1085doi: 10.1038/s43018-021-00247-z.
Westcott, P. M. K., Sacks, N. J., Schenkel, J. M., Ely, Z. A., Smith, O., Hauck, H., Jaeger, A. M., Zhang, D., Backlund, C. M., Beytagh, M. C., Patten, J. J., Elbashir, R., Eng, G., Irvine, D. J., Yilmaz, O. H., & Jacks, T. (2021). Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer. Nature cancer, 2(10), 1071-1085. https://doi.org/10.1038/s43018-021-00247-z
Westcott, Peter M K, et al. "Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer." Nature cancer vol. 2,10 (2021): 1071-1085. doi: https://doi.org/10.1038/s43018-021-00247-z
Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T. Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer. Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30. PMID: 34738089; PMCID: PMC8562866.
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Data on SVCT2 transporter expression and localization in cancer cell lines and tissues.

Data in brief

Roa FJ, Peña E, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI.
PMID: 31249848
Data Brief. 2019 May 06;25:103972. doi: 10.1016/j.dib.2019.103972. eCollection 2019 Aug.

The data presented in this article are related to the research paper entitled "Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer", available in Free Radical Biology and Medicine Journal [1]. In...

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Roa FJ, Peña E, Inostroza E, et al. Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data Brief. 2019;25:103972doi: 10.1016/j.dib.2019.103972.
Roa, F. J., Peña, E., Inostroza, E., Sotomayor, K., González, M., Gutierrez-Castro, F. A., Maurin, M., Sweet, K., Labrousse, C., Gatica, M., Aylwin, C. F., Mendoza, P., Maldonado, M., Delgado, C., Madariaga, J., Panes, J., Silva-Grecchi, T., Concha, I. I., Moraga-Cid, G., Reyes, A. M., Muñoz-Montesino, C., Vera, J. C., & Rivas, C. I. (2019). Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data in brief, 25103972. https://doi.org/10.1016/j.dib.2019.103972
Roa, Francisco J, et al. "Data on SVCT2 transporter expression and localization in cancer cell lines and tissues." Data in brief vol. 25 (2019): 103972. doi: https://doi.org/10.1016/j.dib.2019.103972
Roa FJ, Peña E, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI. Data on SVCT2 transporter expression and localization in cancer cell lines and tissues. Data Brief. 2019 May 06;25:103972. doi: 10.1016/j.dib.2019.103972. eCollection 2019 Aug. PMID: 31249848; PMCID: PMC6586595.
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Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham.

Korean journal for food science of animal resources

Kim SW, Garcia CV, Lee BN, Kwon HJ, Kim JT.
PMID: 29725211
Korean J Food Sci Anim Resour. 2017;37(6):889-897. doi: 10.5851/kosfa.2017.37.6.889. Epub 2017 Dec 31.

In this study, a nanoemulsion formulation for encapsulating turmeric extract was developed and its physicochemical characteristics including particle diameter, zeta potential, polydispersity index, and stability were determined. The turmeric nanoemulsion (TE-NE) droplets exhibited small diameter (165 nm), low PDI...

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Kim SW, Garcia CV, Lee BN, et al. Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham. Korean J Food Sci Anim Resour. 2017;37(6):889-897doi: 10.5851/kosfa.2017.37.6.889.
Kim, S. W., Garcia, C. V., Lee, B. N., Kwon, H. J., & Kim, J. T. (2017). Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham. Korean journal for food science of animal resources, 37(6), 889-897. https://doi.org/10.5851/kosfa.2017.37.6.889
Kim, Seung Wook, et al. "Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham." Korean journal for food science of animal resources vol. 37,6 (2017): 889-897. doi: https://doi.org/10.5851/kosfa.2017.37.6.889
Kim SW, Garcia CV, Lee BN, Kwon HJ, Kim JT. Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham. Korean J Food Sci Anim Resour. 2017;37(6):889-897. doi: 10.5851/kosfa.2017.37.6.889. Epub 2017 Dec 31. PMID: 29725211; PMCID: PMC5932933.
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