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Nova Regulates GABAA Receptor γ2 Alternative Splicing via a Distal Downstream UCAU-Rich Intronic Splicing Enhancer

STEM and diversify

Darnell RB.
GSID: 9u3ATHcGOPoJ
BK Dredge, RB Darnell - Molecular and cellular biology, 2003 - Am Soc Microbiol

… , acting at multiple levels to regulate and diversify gene expression, and such functions are … characterized by loss of inhibitory control of motor neurons in the spinal cord and brainstem. …

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Dredge, B. K., & Darnell, R. B. (2003). Nova regulates GABAA receptor γ2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer. Molecular and cellular biology, 23(13), 4687-4700.
Dredge, B. Kate, and Robert B. Darnell. "Nova regulates GABAA receptor γ2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer." Molecular and cellular biology 23.13 (2003): 4687-4700.
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Quasi-Experimental Study of Functional Family Therapy Effectiveness for Juvenile Justice Aftercare in a Racially and Ethnically Diverse Community Sample.

Children and youth services review

Darnell AJ, Schuler MS.
PMID: 25767310
Child Youth Serv Rev. 2015 Mar;50:75-82. doi: 10.1016/j.childyouth.2015.01.013.

Functional Family Therapy (FFT) is an intensive community-based treatment program designed to reduce youth behavior problems such as violence, drug use, and other delinquency. Although there is evidence of FFT efficacy and effectiveness with predominantly White samples, there is...

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Darnell AJ, Schuler MS. Quasi-Experimental Study of Functional Family Therapy Effectiveness for Juvenile Justice Aftercare in a Racially and Ethnically Diverse Community Sample. Child Youth Serv Rev. 2015;50:75-82doi: 10.1016/j.childyouth.2015.01.013.
Darnell, A. J., & Schuler, M. S. (2015). Quasi-Experimental Study of Functional Family Therapy Effectiveness for Juvenile Justice Aftercare in a Racially and Ethnically Diverse Community Sample. Children and youth services review, 5075-82. https://doi.org/10.1016/j.childyouth.2015.01.013
Darnell, Adam J, and Schuler, Megan S. "Quasi-Experimental Study of Functional Family Therapy Effectiveness for Juvenile Justice Aftercare in a Racially and Ethnically Diverse Community Sample." Children and youth services review vol. 50 (2015): 75-82. doi: https://doi.org/10.1016/j.childyouth.2015.01.013
Darnell AJ, Schuler MS. Quasi-Experimental Study of Functional Family Therapy Effectiveness for Juvenile Justice Aftercare in a Racially and Ethnically Diverse Community Sample. Child Youth Serv Rev. 2015 Mar;50:75-82. doi: 10.1016/j.childyouth.2015.01.013. PMID: 25767310; PMCID: PMC4354807.
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Disease variants in genomes of 44 centenarians.

Molecular genetics & genomic medicine

Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P.
PMID: 25333069
Mol Genet Genomic Med. 2014 Sep;2(5):438-50. doi: 10.1002/mgg3.86. Epub 2014 Jun 15.

To identify previously reported disease mutations that are compatible with extraordinary longevity, we screened the coding regions of the genomes of 44 Ashkenazi Jewish centenarians. Individual genome sequences were generated with 30× coverage on the Illumina HiSeq 2000 and...

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Freudenberg-Hua Y, Freudenberg J, Vacic V, et al. Disease variants in genomes of 44 centenarians. Mol Genet Genomic Med. 2014;2(5):438-50doi: 10.1002/mgg3.86.
Freudenberg-Hua, Y., Freudenberg, J., Vacic, V., Abhyankar, A., Emde, A. K., Ben-Avraham, D., Barzilai, N., Oschwald, D., Christen, E., Koppel, J., Greenwald, B., Darnell, R. B., Germer, S., Atzmon, G., & Davies, P. (2014). Disease variants in genomes of 44 centenarians. Molecular genetics & genomic medicine, 2(5), 438-50. https://doi.org/10.1002/mgg3.86
Freudenberg-Hua, Yun, et al. "Disease variants in genomes of 44 centenarians." Molecular genetics & genomic medicine vol. 2,5 (2014): 438-50. doi: https://doi.org/10.1002/mgg3.86
Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P. Disease variants in genomes of 44 centenarians. Mol Genet Genomic Med. 2014 Sep;2(5):438-50. doi: 10.1002/mgg3.86. Epub 2014 Jun 15. PMID: 25333069; PMCID: PMC4190879.
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Edward Sapir's thought experiment in the interdisciplines of cultural anthropology and psychiatry.

Psychiatry

Darnell R.
PMID: 11383437
Psychiatry. 2001;64(1):17-22. doi: 10.1521/psyc.64.1.17.18234.

No abstract available.

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Darnell R. Edward Sapir's thought experiment in the interdisciplines of cultural anthropology and psychiatry. Psychiatry. 2001;64(1):17-22doi: 10.1521/psyc.64.1.17.18234.
Darnell, R. (2001). Edward Sapir's thought experiment in the interdisciplines of cultural anthropology and psychiatry. Psychiatry, 64(1), 17-22. https://doi.org/10.1521/psyc.64.1.17.18234
Darnell, R. "Edward Sapir's thought experiment in the interdisciplines of cultural anthropology and psychiatry." Psychiatry vol. 64,1 (2001): 17-22. doi: https://doi.org/10.1521/psyc.64.1.17.18234
Darnell R. Edward Sapir's thought experiment in the interdisciplines of cultural anthropology and psychiatry. Psychiatry. 2001;64(1):17-22. doi: 10.1521/psyc.64.1.17.18234. PMID: 11383437.
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Physique and temperament of women delinquents compared with women undergraduates.

The British journal of medical psychology

EPPS P, PARNELL RW.
PMID: 13019010
Br J Med Psychol. 1952;25(4):249-55. doi: 10.1111/j.2044-8341.1952.tb00426.x.

No abstract available.

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EPPS P, PARNELL RW. Physique and temperament of women delinquents compared with women undergraduates. Br J Med Psychol. 1952;25(4):249-55doi: 10.1111/j.2044-8341.1952.tb00426.x.
EPPS, P., & PARNELL, R. W. (1952). Physique and temperament of women delinquents compared with women undergraduates. The British journal of medical psychology, 25(4), 249-55. https://doi.org/10.1111/j.2044-8341.1952.tb00426.x
EPPS, P, and PARNELL, R W. "Physique and temperament of women delinquents compared with women undergraduates." The British journal of medical psychology vol. 25,4 (1952): 249-55. doi: https://doi.org/10.1111/j.2044-8341.1952.tb00426.x
EPPS P, PARNELL RW. Physique and temperament of women delinquents compared with women undergraduates. Br J Med Psychol. 1952;25(4):249-55. doi: 10.1111/j.2044-8341.1952.tb00426.x. PMID: 13019010.
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THE LANGUAGE OF CLERGYMEN.

Science (New York, N.Y.)

Darnell TW, Allen ES.
PMID: 17735347
Science. 1931 Jan 16;73(1881):68. doi: 10.1126/science.73.1881.68.

No abstract available.

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Darnell TW, Allen ES. THE LANGUAGE OF CLERGYMEN. Science. 1931;73(1881):68doi: 10.1126/science.73.1881.68.
Darnell, T. W., & Allen, E. S. (1931). THE LANGUAGE OF CLERGYMEN. Science (New York, N.Y.), 73(1881), 68. https://doi.org/10.1126/science.73.1881.68
Darnell, T W, and Allen, E S. "THE LANGUAGE OF CLERGYMEN." Science (New York, N.Y.) vol. 73,1881 (1931): 68. doi: https://doi.org/10.1126/science.73.1881.68
Darnell TW, Allen ES. THE LANGUAGE OF CLERGYMEN. Science. 1931 Jan 16;73(1881):68. doi: 10.1126/science.73.1881.68. PMID: 17735347.
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Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma.

HPB : the official journal of the International Hepato Pancreato Biliary Association

Baskin-Bey ES, Devarbhavi HC, Nagorney DM, Farnell MB, Donohue JH, Sanderson SO, Stadheim LM, Gores GJ.
PMID: 18333208
HPB (Oxford). 2005;7(4):283-8. doi: 10.1080/13651820500292954.

OBJECTIVE: Distinguishing between malignant and benign biliary strictures remains problematic. The aim of this study was to compare and contrast the clinical features of patients with benign and malignant biliary strictures.METHODS: Medical records of patients who underwent surgical resection...

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Baskin-Bey ES, Devarbhavi HC, Nagorney DM, et al. Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma. HPB (Oxford). 2005;7(4):283-8doi: 10.1080/13651820500292954.
Baskin-Bey, E. S., Devarbhavi, H. C., Nagorney, D. M., Farnell, M. B., Donohue, J. H., Sanderson, S. O., Stadheim, L. M., & Gores, G. J. (2005). Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma. HPB : the official journal of the International Hepato Pancreato Biliary Association, 7(4), 283-8. https://doi.org/10.1080/13651820500292954
Baskin-Bey, E S, et al. "Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma." HPB : the official journal of the International Hepato Pancreato Biliary Association vol. 7,4 (2005): 283-8. doi: https://doi.org/10.1080/13651820500292954
Baskin-Bey ES, Devarbhavi HC, Nagorney DM, Farnell MB, Donohue JH, Sanderson SO, Stadheim LM, Gores GJ. Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma. HPB (Oxford). 2005;7(4):283-8. doi: 10.1080/13651820500292954. PMID: 18333208; PMCID: PMC2043108.
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Surgery 2010: Finding the silver lining on a cloud of regulation.

Journal of the American College of Surgeons

Farnell MB.
PMID: 21700172
J Am Coll Surg. 2011 Jul;213(1):1-9. doi: 10.1016/j.jamcollsurg.2011.01.011.

No abstract available.

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Farnell MB. Surgery 2010: Finding the silver lining on a cloud of regulation. J Am Coll Surg. 2011;213(1):1-9doi: 10.1016/j.jamcollsurg.2011.01.011.
Farnell, M. B. (2011). Surgery 2010: Finding the silver lining on a cloud of regulation. Journal of the American College of Surgeons, 213(1), 1-9. https://doi.org/10.1016/j.jamcollsurg.2011.01.011
Farnell, Michael B. "Surgery 2010: Finding the silver lining on a cloud of regulation." Journal of the American College of Surgeons vol. 213,1 (2011): 1-9. doi: https://doi.org/10.1016/j.jamcollsurg.2011.01.011
Farnell MB. Surgery 2010: Finding the silver lining on a cloud of regulation. J Am Coll Surg. 2011 Jul;213(1):1-9. doi: 10.1016/j.jamcollsurg.2011.01.011. PMID: 21700172.
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Bismuth in the Treatment of Syphilis.

Proceedings of the Royal Society of Medicine

Parnell RJ.
PMID: 19984212
Proc R Soc Med. 1924;17:19-26.

No abstract available.

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Parnell RJ. Bismuth in the Treatment of Syphilis. Proc R Soc Med. 1924;17:19-26
Parnell, R. J. (1924). Bismuth in the Treatment of Syphilis. Proceedings of the Royal Society of Medicine, 1719-26.
Parnell, R J. "Bismuth in the Treatment of Syphilis." Proceedings of the Royal Society of Medicine vol. 17 (1924): 19-26.
Parnell RJ. Bismuth in the Treatment of Syphilis. Proc R Soc Med. 1924;17:19-26. PMID: 19984212; PMCID: PMC2201253.
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Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women.

Nutrition & metabolism

Alvarez JA, Bush NC, Choquette SS, Hunter GR, Darnell BE, Oster RA, Gower BA.
PMID: 20398267
Nutr Metab (Lond). 2010 Apr 14;7:28. doi: 10.1186/1743-7075-7-28.

BACKGROUND: The prevalence of type 2 diabetes is higher among African Americans (AA) vs European Americans (EA), independent of obesity and other known confounders. Although the reason for this disparity is not known, it is possible that relatively low...

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Alvarez JA, Bush NC, Choquette SS, et al. Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women. Nutr Metab (Lond). 2010;7:28doi: 10.1186/1743-7075-7-28.
Alvarez, J. A., Bush, N. C., Choquette, S. S., Hunter, G. R., Darnell, B. E., Oster, R. A., & Gower, B. A. (2010). Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women. Nutrition & metabolism, 728. https://doi.org/10.1186/1743-7075-7-28
Alvarez, Jessica A, et al. "Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women." Nutrition & metabolism vol. 7 (2010): 28. doi: https://doi.org/10.1186/1743-7075-7-28
Alvarez JA, Bush NC, Choquette SS, Hunter GR, Darnell BE, Oster RA, Gower BA. Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women. Nutr Metab (Lond). 2010 Apr 14;7:28. doi: 10.1186/1743-7075-7-28. PMID: 20398267; PMCID: PMC2868016.
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The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite.

Frontiers in neural circuits

Racca C, Gardiol A, Eom T, Ule J, Triller A, Darnell RB.
PMID: 20407637
Front Neural Circuits. 2010 Mar 03;4:5. doi: 10.3389/neuro.04.005.2010. eCollection 2010.

Nova proteins are neuron-specific RNA binding proteins targeted by autoantibodies in a disorder manifest by failure of motor inhibition, and they regulate splicing and alternative 3' processing. Nova regulates splicing of RNAs encoding synaptic proteins, including the inhibitory glycine...

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Racca C, Gardiol A, Eom T, et al. The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Front Neural Circuits. 2010;4:5doi: 10.3389/neuro.04.005.2010.
Racca, C., Gardiol, A., Eom, T., Ule, J., Triller, A., & Darnell, R. B. (2010). The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Frontiers in neural circuits, 45. https://doi.org/10.3389/neuro.04.005.2010
Racca, Claudia, et al. "The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite." Frontiers in neural circuits vol. 4 (2010): 5. doi: https://doi.org/10.3389/neuro.04.005.2010
Racca C, Gardiol A, Eom T, Ule J, Triller A, Darnell RB. The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Front Neural Circuits. 2010 Mar 03;4:5. doi: 10.3389/neuro.04.005.2010. eCollection 2010. PMID: 20407637; PMCID: PMC2856630.
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RNA regulation in neurologic disease and cancer.

Cancer research and treatment

Darnell RB.
PMID: 20948916
Cancer Res Treat. 2010 Sep;42(3):125-9. doi: 10.4143/crt.2010.42.3.125. Epub 2010 Sep 30.

The paraneoplastic neurologic diseases (PNDs) are brain degenerations that develop in the setting of clinically inapparent cancers. PNDs arise when common cancers express brain proteins, triggering an anti-tumor immune response and tumor immunity. Research on these brain-cancer proteins has...

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Darnell RB. RNA regulation in neurologic disease and cancer. Cancer Res Treat. 2010;42(3):125-9doi: 10.4143/crt.2010.42.3.125.
Darnell, R. B. (2010). RNA regulation in neurologic disease and cancer. Cancer research and treatment, 42(3), 125-9. https://doi.org/10.4143/crt.2010.42.3.125
Darnell, Robert B. "RNA regulation in neurologic disease and cancer." Cancer research and treatment vol. 42,3 (2010): 125-9. doi: https://doi.org/10.4143/crt.2010.42.3.125
Darnell RB. RNA regulation in neurologic disease and cancer. Cancer Res Treat. 2010 Sep;42(3):125-9. doi: 10.4143/crt.2010.42.3.125. Epub 2010 Sep 30. PMID: 20948916; PMCID: PMC2953774.
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Showing 1 to 12 of 94 entries