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Showing 1 to 12 of 67 entries
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Gait Is Associated with Cognitive Flexibility: A Dual-Tasking Study in Healthy Older People.

Frontiers in aging neuroscience

Hobert MA, Meyer SI, Hasmann SE, Metzger FG, Suenkel U, Eschweiler GW, Berg D, Maetzler W.
PMID: 28596731
Front Aging Neurosci. 2017 May 24;9:154. doi: 10.3389/fnagi.2017.00154. eCollection 2017.

No abstract available.

Intake of silica nanoparticles by giant lipid vesicles: influence of particle size and thermodynamic membrane state.

Beilstein journal of nanotechnology

Strobl FG, Seitz F, Westerhausen C, Reller A, Torrano AA, Bräuchle C, Wixforth A, Schneider MF.
PMID: 25671142
Beilstein J Nanotechnol. 2014 Dec 23;5:2468-78. doi: 10.3762/bjnano.5.256. eCollection 2014.

The uptake of nanoparticles into cells often involves their engulfment by the plasma membrane and a fission of the latter. Understanding the physical mechanisms underlying these uptake processes may be achieved by the investigation of simple model systems that...

Pharmacochemistry of the platelet purinergic receptors.

Purinergic signalling

Jacobson KA, Deflorian F, Mishra S, Costanzi S.
PMID: 21484092
Purinergic Signal. 2011 Sep;7(3):305-24. doi: 10.1007/s11302-011-9216-0. Epub 2011 Feb 18.

Platelets contain at least five purinergic G protein-coupled receptors, e.g., the pro-aggregatory P2Y(1) and P2Y(12) receptors, a P2Y(14) receptor (GPR105) of unknown function, and anti-aggregatory A(2A) and A(2B) adenosine receptor (ARs), in addition to the ligand-gated P2X1 ion channel....

Combining ligand-based and structure-based drug design in the virtual screening arena.

Expert opinion on drug discovery

Moro S, Bacilieri M, Deflorian F.
PMID: 23496036
Expert Opin Drug Discov. 2007 Jan;2(1):37-49. doi: 10.1517/17460441.2.1.37.

The aim of virtual high-throughput screening is the identification of biologically relevant molecules among either tangible or virtual (large) collections of compounds. Likewise, high-throughput screening (HTS) and high-throughput virtual screening (HTVS) methods are becoming very important within the drug...

Polarized parton distributions.

Physical review. D, Particles and fields

de Florian D, Epele LN, Fanchiotti H, García Canal CA, Sassot R.
PMID: 10018269
Phys Rev D Part Fields. 1995 Jan 01;51(1):37-43. doi: 10.1103/physrevd.51.37.

No abstract available.

Glutamate Signaling in the Fly Visual System.

iScience

Richter FG, Fendl S, Haag J, Drews MS, Borst A.
PMID: 30267688
iScience. 2018 Sep 28;7:85-95. doi: 10.1016/j.isci.2018.08.019. Epub 2018 Aug 29.

For a proper understanding of neural circuit function, it is important to know which signals neurons relay to their downstream partners. Calcium imaging with genetically encoded calcium sensors like GCaMP has become the default approach for mapping these responses....

Effect of the Organic Functional Group on the Grafting Ability of Trialkoxysilanes onto Graphene Oxide: A Combined NMR, XRD, and ESR Study.

Materials (Basel, Switzerland)

Calovi M, Callone E, Ceccato R, Deflorian F, Rossi S, Dirè S.
PMID: 31766378
Materials (Basel). 2019 Nov 21;12(23). doi: 10.3390/ma12233828.

The functional properties displayed by graphene oxide (GO)-polymer nanocomposites are strongly affected by the dispersion ability of GO sheets in the polymeric matrix, which can be largely improved by functionalization with organosilanes. The grafting to GO of organosilanes with...

Expert-based medication reviews to reduce polypharmacy in older patients in primary care: a northern-Italian cluster-randomised controlled trial.

BMC geriatrics

Mahlknecht A, Wiedermann CJ, Sandri M, Engl A, Valentini M, Vögele A, Schmid S, Deflorian F, Montalbano C, Koper D, Bellmann R, Sönnichsen A, Piccoliori G.
PMID: 34814835
BMC Geriatr. 2021 Nov 23;21(1):659. doi: 10.1186/s12877-021-02612-0.

BACKGROUND: Evidence regarding clinically relevant effects of interventions aiming at reducing polypharmacy is weak, especially for the primary care setting. This study was initiated with the objective to achieve clinical benefits for older patients (aged 75+) by means of...

Monocyte chemoattractant protein-1 predicts the development of diabetic nephropathy.

Diabetes/metabolism research and reviews

Scurt FG, Menne J, Brandt S, Bernhardt A, Mertens PR, Haller H, Chatzikyrkou C.
PMID: 34541760
Diabetes Metab Res Rev. 2021 Sep 20;e3497. doi: 10.1002/dmrr.3497. Epub 2021 Sep 20.

AIM: Diabetic nephropathy (DN) is a devastating complication of diabetes mellitus (DM). Therefore, screening strategies in order to prevent its development and/or retard its progression are of paramount importance. We investigated if monocyte chemoattractant protein-1 (MCP-1) was associated with...

Systemic Inflammation Precedes Microalbuminuria in Diabetes.

Kidney international reports

Scurt FG, Menne J, Brandt S, Bernhardt A, Mertens PR, Haller H, Chatzikyrkou C.
PMID: 31701047
Kidney Int Rep. 2019 Jun 21;4(10):1373-1386. doi: 10.1016/j.ekir.2019.06.005. eCollection 2019 Oct.

AIM: The aim of the case-control study was to investigate if serum biomarkers indicative of vascular inflammation and endothelial dysfunction can predict the development of microalbuminuria in patients with diabetes mellitus type 2.METHODS: Among participants enrolled in the ROADMAP...

HDAC8: A Promising Therapeutic Target for Acute Myeloid Leukemia.

Frontiers in cell and developmental biology

Spreafico M, Gruszka AM, Valli D, Mazzola M, Deflorian G, Quintè A, Totaro MG, Battaglia C, Alcalay M, Marozzi A, Pistocchi A.
PMID: 33015043
Front Cell Dev Biol. 2020 Sep 04;8:844. doi: 10.3389/fcell.2020.00844. eCollection 2020.

Histone deacetylase 8 (HDAC8), a class I HDAC that modifies non-histone proteins such as p53, is highly expressed in different hematological neoplasms including a subtype of acute myeloid leukemia (AML) bearing inversion of chromosome 16 [inv(16)]. To investigate HDAC8...

Healing of Post-Extraction Sockets Filled with Anorganic Bovine Bone and Covered with a Xenogeneic Collagen Matrix. Radiological 2D and 3D Results of a Pilot Study to Assess Dimensional Stability.

Materials (Basel, Switzerland)

Testori T, Deflorian MA, Mandelli F, Attardo G, Maiorana C, Del Fabbro M, Vinci R.
PMID: 34064679
Materials (Basel). 2021 May 11;14(10). doi: 10.3390/ma14102473.

Analysis of short-term results regarding dimensional stability of post-extraction sockets managed via a preservation protocol using deproteinized bovine bone matrix and a xenogeneic collagen matrix. Materials and methods Fifteen patients needing extraction of one single-rooted premolar tooth were treated...

Showing 1 to 12 of 67 entries