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DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

NPJ breast cancer

Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L.
PMID: 28948212
NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017.

Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature. However, not all triple negative patients achieved pathologic complete response...

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Wolf DM, Yau C, Sanil A, et al. DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. NPJ Breast Cancer. 2017;3:31doi: 10.1038/s41523-017-0025-7.
Wolf, D. M., Yau, C., Sanil, A., Glas, A., Petricoin, E., Wulfkuhle, J., Severson, T. M., Linn, S., Brown-Swigart, L., Hirst, G., Buxton, M., DeMichele, A., Hylton, N., Symmans, F., Yee, D., Paoloni, M., Esserman, L., Berry, D., Rugo, H., Olopade, O., & van 't Veer, L. (2017). DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. NPJ breast cancer, 331. https://doi.org/10.1038/s41523-017-0025-7
Wolf, Denise M, et al. "DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial." NPJ breast cancer vol. 3 (2017): 31. doi: https://doi.org/10.1038/s41523-017-0025-7
Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L. DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017. PMID: 28948212; PMCID: PMC5572474.
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OC-15 - Risk factors for cancer development after idiopathic venous thromboembolism.

Thrombosis research

Cosmi B, Legnani C, Ghirarduzzi A, De Micheli V, Pengo V, Testa S, Poli D, Antonucci E, Prisco D, Tripodi A, Prandoni P, Palareti G.
PMID: 27161686
Thromb Res. 2016 Apr;140:S174. doi: 10.1016/S0049-3848(16)30132-3. Epub 2016 Apr 08.

INTRODUCTION: Idiopathic venous thromboembolism (VTE) is associated with the risk of cancer but the risk factors for cancer development in such patients are still uncertain.AIM: To assess risk factors for the development of cancer after a standard course of...

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Cosmi B, Legnani C, Ghirarduzzi A, et al. OC-15 - Risk factors for cancer development after idiopathic venous thromboembolism. Thromb Res. 2016;140:S174doi: 10.1016/S0049-3848(16)30132-3.
Cosmi, B., Legnani, C., Ghirarduzzi, A., De Micheli, V., Pengo, V., Testa, S., Poli, D., Antonucci, E., Prisco, D., Tripodi, A., Prandoni, P., Palareti, G. (2016). OC-15 - Risk factors for cancer development after idiopathic venous thromboembolism. Thrombosis research, 140S174. https://doi.org/10.1016/S0049-3848(16)30132-3
Cosmi, B, et al. "OC-15 - Risk factors for cancer development after idiopathic venous thromboembolism." Thrombosis research vol. 140 (2016): S174. doi: https://doi.org/10.1016/S0049-3848(16)30132-3
Cosmi B, Legnani C, Ghirarduzzi A, De Micheli V, Pengo V, Testa S, Poli D, Antonucci E, Prisco D, Tripodi A, Prandoni P, Palareti G. OC-15 - Risk factors for cancer development after idiopathic venous thromboembolism. Thromb Res. 2016 Apr;140:S174. doi: 10.1016/S0049-3848(16)30132-3. Epub 2016 Apr 08. PMID: 27161686.
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Multimodal hazard rate for relapse in breast cancer: quality of data and calibration of computer simulation.

Cancers

Retsky M, Demicheli R.
PMID: 25437254
Cancers (Basel). 2014 Nov 27;6(4):2343-55. doi: 10.3390/cancers6042343.

Much has occurred since our 2010 report in Cancers. In the past few years we published several extensive reviews of our research so a brief review is all that will be provided here. We proposed in the earlier reports...

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Retsky M, Demicheli R. Multimodal hazard rate for relapse in breast cancer: quality of data and calibration of computer simulation. Cancers (Basel). 2014;6(4):2343-55doi: 10.3390/cancers6042343.
Retsky, M., & Demicheli, R. (2014). Multimodal hazard rate for relapse in breast cancer: quality of data and calibration of computer simulation. Cancers, 6(4), 2343-55. https://doi.org/10.3390/cancers6042343
Retsky, Michael, and Demicheli, Romano. "Multimodal hazard rate for relapse in breast cancer: quality of data and calibration of computer simulation." Cancers vol. 6,4 (2014): 2343-55. doi: https://doi.org/10.3390/cancers6042343
Retsky M, Demicheli R. Multimodal hazard rate for relapse in breast cancer: quality of data and calibration of computer simulation. Cancers (Basel). 2014 Nov 27;6(4):2343-55. doi: 10.3390/cancers6042343. PMID: 25437254; PMCID: PMC4276970.
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Breast DCE-MRI Kinetic Heterogeneity Tumor Markers: Preliminary Associations With Neoadjuvant Chemotherapy Response.

Translational oncology

Ashraf A, Gaonkar B, Mies C, DeMichele A, Rosen M, Davatzikos C, Kontos D, Bourke T, Ryan M.
PMID: 26055172
Transl Oncol. 2015 Jun;8(3):154-62. doi: 10.1016/j.tranon.2015.03.005.

The ability to predict response to neoadjuvant chemotherapy for women diagnosed with breast cancer, either before or early on in treatment, is critical to judicious patient selection and tailoring the treatment regimen. In this paper, we investigate the role...

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Ashraf A, Gaonkar B, Mies C, et al. Breast DCE-MRI Kinetic Heterogeneity Tumor Markers: Preliminary Associations With Neoadjuvant Chemotherapy Response. Transl Oncol. 2015;8(3):154-62doi: 10.1016/j.tranon.2015.03.005.
Ashraf, A., Gaonkar, B., Mies, C., DeMichele, A., Rosen, M., Davatzikos, C., Kontos, D., Bourke, T., & Ryan, M. (2015). Breast DCE-MRI Kinetic Heterogeneity Tumor Markers: Preliminary Associations With Neoadjuvant Chemotherapy Response. Translational oncology, 8(3), 154-62. https://doi.org/10.1016/j.tranon.2015.03.005
Ashraf, Ahmed, et al. "Breast DCE-MRI Kinetic Heterogeneity Tumor Markers: Preliminary Associations With Neoadjuvant Chemotherapy Response." Translational oncology vol. 8,3 (2015): 154-62. doi: https://doi.org/10.1016/j.tranon.2015.03.005
Ashraf A, Gaonkar B, Mies C, DeMichele A, Rosen M, Davatzikos C, Kontos D, Bourke T, Ryan M. Breast DCE-MRI Kinetic Heterogeneity Tumor Markers: Preliminary Associations With Neoadjuvant Chemotherapy Response. Transl Oncol. 2015 Jun;8(3):154-62. doi: 10.1016/j.tranon.2015.03.005. PMID: 26055172; PMCID: PMC4487265.
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Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents.

Bioinorganic chemistry and applications

Silva SR, Duarte ÉC, Ramos GS, Kock FV, Andrade FD, Frézard F, Colnago LA, Demicheli C.
PMID: 26347596
Bioinorg Chem Appl. 2015;2015:942147. doi: 10.1155/2015/942147. Epub 2015 Aug 10.

Complexes of gadolinium(III) with N-octanoyl-N-methylglucamine (L8) and N-decanoyl-N-methylglucamine (L10) with 1 : 2 stoichiometry were synthesized and characterized by elemental analysis, electrospray ionization-tandem mass spectrometry (ESI-MS), infrared (IR) spectroscopy, and molar conductivity measurements. The transverse (r 2) and longitudinal...

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Silva SR, Duarte ÉC, Ramos GS, et al. Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents. Bioinorg Chem Appl. 2015;2015:942147doi: 10.1155/2015/942147.
Silva, S. R., Duarte, �. �. C., Ramos, G. S., Kock, F. V., Andrade, F. D., Frézard, F., Colnago, L. A., & Demicheli, C. (2015). Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents. Bioinorganic chemistry and applications, 2015942147. https://doi.org/10.1155/2015/942147
Silva, Simone Rodrigues, et al. "Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents." Bioinorganic chemistry and applications vol. 2015 (2015): 942147. doi: https://doi.org/10.1155/2015/942147
Silva SR, Duarte ÉC, Ramos GS, Kock FV, Andrade FD, Frézard F, Colnago LA, Demicheli C. Gadolinium(III) Complexes with N-Alkyl-N-methylglucamine Surfactants Incorporated into Liposomes as Potential MRI Contrast Agents. Bioinorg Chem Appl. 2015;2015:942147. doi: 10.1155/2015/942147. Epub 2015 Aug 10. PMID: 26347596; PMCID: PMC4546952.
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Anomalous dynamics of intruders in a crowded environment of mobile obstacles.

Nature communications

Sentjabrskaja T, Zaccarelli E, De Michele C, Sciortino F, Tartaglia P, Voigtmann T, Egelhaaf SU, Laurati M.
PMID: 27041068
Nat Commun. 2016 Apr 04;7:11133. doi: 10.1038/ncomms11133.

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collectives and vehicular traffic conditions. These are examples of motion through crowded environments,...

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Sentjabrskaja T, Zaccarelli E, De Michele C, et al. Anomalous dynamics of intruders in a crowded environment of mobile obstacles. Nat Commun. 2016;7:11133doi: 10.1038/ncomms11133.
Sentjabrskaja, T., Zaccarelli, E., De Michele, C., Sciortino, F., Tartaglia, P., Voigtmann, T., Egelhaaf, S. U., & Laurati, M. (2016). Anomalous dynamics of intruders in a crowded environment of mobile obstacles. Nature communications, 711133. https://doi.org/10.1038/ncomms11133
Sentjabrskaja, Tatjana, et al. "Anomalous dynamics of intruders in a crowded environment of mobile obstacles." Nature communications vol. 7 (2016): 11133. doi: https://doi.org/10.1038/ncomms11133
Sentjabrskaja T, Zaccarelli E, De Michele C, Sciortino F, Tartaglia P, Voigtmann T, Egelhaaf SU, Laurati M. Anomalous dynamics of intruders in a crowded environment of mobile obstacles. Nat Commun. 2016 Apr 04;7:11133. doi: 10.1038/ncomms11133. PMID: 27041068; PMCID: PMC4822008.
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Phase-matched second harmonic generation with on-chip GaN-on-Si microdisks.

Scientific reports

Roland I, Gromovyi M, Zeng Y, El Kurdi M, Sauvage S, Brimont C, Guillet T, Gayral B, Semond F, Duboz JY, de Micheli M, Checoury X, Boucaud P.
PMID: 27687007
Sci Rep. 2016 Sep 30;6:34191. doi: 10.1038/srep34191.

We demonstrate phase-matched second harmonic generation in gallium nitride on silicon microdisks. The microdisks are integrated with side-coupling bus waveguides in a two-dimensional photonic circuit. The second harmonic generation is excited with a continuous wave laser in the telecom...

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Roland I, Gromovyi M, Zeng Y, et al. Phase-matched second harmonic generation with on-chip GaN-on-Si microdisks. Sci Rep. 2016;6:34191doi: 10.1038/srep34191.
Roland, I., Gromovyi, M., Zeng, Y., El Kurdi, M., Sauvage, S., Brimont, C., Guillet, T., Gayral, B., Semond, F., Duboz, J. Y., de Micheli, M., Checoury, X., & Boucaud, P. (2016). Phase-matched second harmonic generation with on-chip GaN-on-Si microdisks. Scientific reports, 634191. https://doi.org/10.1038/srep34191
Roland, I, et al. "Phase-matched second harmonic generation with on-chip GaN-on-Si microdisks." Scientific reports vol. 6 (2016): 34191. doi: https://doi.org/10.1038/srep34191
Roland I, Gromovyi M, Zeng Y, El Kurdi M, Sauvage S, Brimont C, Guillet T, Gayral B, Semond F, Duboz JY, de Micheli M, Checoury X, Boucaud P. Phase-matched second harmonic generation with on-chip GaN-on-Si microdisks. Sci Rep. 2016 Sep 30;6:34191. doi: 10.1038/srep34191. PMID: 27687007; PMCID: PMC5043238.
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Hit and go CAS9 delivered through a lentiviral based self-limiting circuit.

Nature communications

Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, Zasso J, Conti L, Demichelis F, Cereseto A.
PMID: 28530235
Nat Commun. 2017 May 22;8:15334. doi: 10.1038/ncomms15334.

In vivo application of the CRISPR-Cas9 technology is still limited by unwanted Cas9 genomic cleavages. Long-term expression of Cas9 increases the number of genomic loci non-specifically cleaved by the nuclease. Here we develop a Self-Limiting Cas9 circuit for Enhanced...

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Petris G, Casini A, Montagna C, et al. Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Nat Commun. 2017;8:15334doi: 10.1038/ncomms15334.
Petris, G., Casini, A., Montagna, C., Lorenzin, F., Prandi, D., Romanel, A., Zasso, J., Conti, L., Demichelis, F., & Cereseto, A. (2017). Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Nature communications, 815334. https://doi.org/10.1038/ncomms15334
Petris, Gianluca, et al. "Hit and go CAS9 delivered through a lentiviral based self-limiting circuit." Nature communications vol. 8 (2017): 15334. doi: https://doi.org/10.1038/ncomms15334
Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, Zasso J, Conti L, Demichelis F, Cereseto A. Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Nat Commun. 2017 May 22;8:15334. doi: 10.1038/ncomms15334. PMID: 28530235; PMCID: PMC5458126.
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High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs).

Journal of the Optical Society of America. A, Optics, image science, and vision

Laberdesque R, Gauthier-Lafaye O, Camon H, Monmayrant A, Petit M, Demichel O, Cluzel B.
PMID: 26560912
J Opt Soc Am A Opt Image Sci Vis. 2015 Nov 01;32(11):1973-81. doi: 10.1364/JOSAA.32.001973.

Cavity-resonator-integrated guided-mode resonance filters (CRIGFs) are optical filters based on weak coupling by a grating between a free-space propagating optical mode and a guided mode, like guided-mode resonance filters (GMRFs). As compared to GMRFs they offer narrowband reflection with...

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Laberdesque R, Gauthier-Lafaye O, Camon H, et al. High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs). J Opt Soc Am A Opt Image Sci Vis. 2015;32(11):1973-81doi: 10.1364/JOSAA.32.001973.
Laberdesque, R., Gauthier-Lafaye, O., Camon, H., Monmayrant, A., Petit, M., Demichel, O., & Cluzel, B. (2015). High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs). Journal of the Optical Society of America. A, Optics, image science, and vision, 32(11), 1973-81. https://doi.org/10.1364/JOSAA.32.001973
Laberdesque, R, et al. "High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs)." Journal of the Optical Society of America. A, Optics, image science, and vision vol. 32,11 (2015): 1973-81. doi: https://doi.org/10.1364/JOSAA.32.001973
Laberdesque R, Gauthier-Lafaye O, Camon H, Monmayrant A, Petit M, Demichel O, Cluzel B. High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs). J Opt Soc Am A Opt Image Sci Vis. 2015 Nov 01;32(11):1973-81. doi: 10.1364/JOSAA.32.001973. PMID: 26560912.
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[Usefulness of vector analysis of the electrocardiogram].

Archivos de cardiologia de Mexico

de Micheli A, Medrano GA.
PMID: 11665661
Arch Cardiol Mex. 2001 Jul-Sep;71(3):237-40.

An electrocardiogram corresponding to an obese, hypertensive woman 52 years old, is presented. It shows a left bundle branch block of advanced degree and the AQRSF at 70 degrees. In this case, the key of the electrocardiographic diagnosis is...

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de Micheli A, Medrano GA. Utilidad del análisis vectorial del electrocardiograma. [Usefulness of vector analysis of the electrocardiogram]. Arch Cardiol Mex. 2001;71(3):237-40
de Micheli, A., & Medrano, G. A. (2001). Utilidad del análisis vectorial del electrocardiograma. [Usefulness of vector analysis of the electrocardiogram]. Archivos de cardiologia de Mexico, 71(3), 237-40.
de Micheli, A, and Medrano, G A. "Utilidad del análisis vectorial del electrocardiograma." [Usefulness of vector analysis of the electrocardiogram]. Archivos de cardiologia de Mexico vol. 71,3 (2001): 237-40.
de Micheli A, Medrano GA. Utilidad del análisis vectorial del electrocardiograma. [Usefulness of vector analysis of the electrocardiogram]. Arch Cardiol Mex. 2001 Jul-Sep;71(3):237-40. Spanish. PMID: 11665661.
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[Chronic osteomyelitis: a new therapeutical idea].

Reumatismo

Carlino G, Trande P, Muratore M, De Micheli E, Santacesaria G.
PMID: 12089625
Reumatismo. 2001;53(4):309-311. doi: 10.4081/reumatismo.2001.309.

We studied the case of a male patient aged 43 affected by post-traumatic chronic osteomyelitis with frequent relapses. Having supposed an insufficiency of the arterial and venous microcirculation in perilesional bone and soft tissue we decided for a therapy...

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Carlino G, Trande P, Muratore M, et al. Osteomielite cronica: una nuova idea terapeutica. [Chronic osteomyelitis: a new therapeutical idea]. Reumatismo. 2001;53(4):309-311doi: 10.4081/reumatismo.2001.309.
Carlino, G., Trande, P., Muratore, M., De Micheli, E., & Santacesaria, G. (2001). Osteomielite cronica: una nuova idea terapeutica. [Chronic osteomyelitis: a new therapeutical idea]. Reumatismo, 53(4), 309-311. https://doi.org/10.4081/reumatismo.2001.309
Carlino, G., et al. "Osteomielite cronica: una nuova idea terapeutica." [Chronic osteomyelitis: a new therapeutical idea]. Reumatismo vol. 53,4 (2001): 309-311. doi: https://doi.org/10.4081/reumatismo.2001.309
Carlino G, Trande P, Muratore M, De Micheli E, Santacesaria G. Osteomielite cronica: una nuova idea terapeutica. [Chronic osteomyelitis: a new therapeutical idea]. Reumatismo. 2001;53(4):309-311. doi: 10.4081/reumatismo.2001.309. Italian. PMID: 12089625.
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[The centennial of the Einthoven electrocardiograph. Part I].

Archivos de cardiologia de Mexico

de Micheli A.
PMID: 11565309
Arch Cardiol Mex. 2001 Apr-Jun;71(2):160-6.

The initial studies about the "irritability" of animal tissues by iatrophysic or iatromechanic scientists are reviewed. These studies led to discover the so called animal electricity envisaged by Luigi Galvani in the XVIII century and demonstrated by Carlo Matteucci...

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de Micheli A. El centenario del electrocardiógrafo de Einthoven. Parte I. [The centennial of the Einthoven electrocardiograph. Part I]. Arch Cardiol Mex. 2001;71(2):160-6
de Micheli, A. (2001). El centenario del electrocardiógrafo de Einthoven. Parte I. [The centennial of the Einthoven electrocardiograph. Part I]. Archivos de cardiologia de Mexico, 71(2), 160-6.
de Micheli, A. "El centenario del electrocardiógrafo de Einthoven. Parte I." [The centennial of the Einthoven electrocardiograph. Part I]. Archivos de cardiologia de Mexico vol. 71,2 (2001): 160-6.
de Micheli A. El centenario del electrocardiógrafo de Einthoven. Parte I. [The centennial of the Einthoven electrocardiograph. Part I]. Arch Cardiol Mex. 2001 Apr-Jun;71(2):160-6. Spanish. PMID: 11565309.
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Showing 1 to 12 of 259 entries